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Search results 1 to 89 out of 89 for Slfn5

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Hits by Strain

Type Details Score
Gene
162394 | SLFN5
Type: gene
Organism: human
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Gene
303377 | Slfn5
Type: gene
Organism: rat
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Gene
468216 | SLFN5
Type: gene
Organism: chimpanzee
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Gene
100686194 | SLFN5
Type: gene
Organism: dog, domestic
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Gene
715462 | SLFN5
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1329004 | Slfn5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR029671 | Slfn5
Type: Family
Description: The Schlafen (SLFN) family includes several mouse and human member genes that have been implicated in important functions, such as the control of cell proliferation, induction of immune responses, and the regulation of viral replication [, , , ]. Mouse and human SLFN proteins are regulated by interferons (IFNs) []. All SLFNs contain an unique Slfn box. SLFN family is comprised of 3 groups, based on the size of the encoded proteins [, , , ]:Group1: Slfn1, Slfn2, and Slfn Like 1.Group2: Slfn3, Slfn4 and Slfn12.Group3: Slfn5, Slfn8-11, Slfn13 and Slfn14.Comparing to group1 proteins, group2 and 3 proteins contain an extra SWADL domain C terminus to the AAA domain. Group3 proteins also possess a large extension C terminus to their SWADL domain. This C-terminal extension is homologous to the superfamily I of DNA/RNA helicases []. It has been proposed that the divergent AAA ATPase domain may function as an RNA-binding domain []. Slfn5 has a role in hematopoietic cell differentiation []. Human Slfn5 has been shown to exhibit negative regulatory effects on anchorage-independent malignant melanoma cell growth and invasion in collagen [].
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Publication
18355440 | J:134155
First Author: Neumann B
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Subcellular localization of the Schlafen protein family.
Volume: 370
Issue: 1
Pages: 62-6
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Publication
15351786 | J:93660
First Author: Geserick P
Year: 2004
Journal: Int Immunol
Title: Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif.
Volume: 16
Issue: 10
Pages: 1535-48
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Publication
20956525 | -
First Author: Katsoulidis E
Year: 2010
Journal: J Biol Chem
Title: Role of interferon {alpha} (IFN{alpha})-inducible Schlafen-5 in regulation of anchorage-independent growth and invasion of malignant melanoma cells.
Volume: 285
Issue: 51
Pages: 40333-41
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Protein
A0A1G5SJC9
Organism: Mus musculus/domesticus
Length: 399  
Fragment?: false
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Protein
Q3V3J5
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: true
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Protein
F8WH72
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: true
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Protein
Q3TAE9
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: true
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Protein
Q8CBA2
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Protein
A0A1G5SJC0
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Protein
A0A1G5SK44
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Protein
A0A1G5SJR4
Organism: Mus musculus/domesticus
Length: 884  
Fragment?: false
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Publication
23570387 | -
First Author: Mavrommatis E
Year: 2013
Journal: J Interferon Cytokine Res
Title: The schlafen family of proteins and their regulation by interferons.
Volume: 33
Issue: 4
Pages: 206-10
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Publication
34707099 | -
First Author: Chen J
Year: 2021
Journal: Nat Commun
Title: Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells.
Volume: 12
Issue: 1
Pages: 6204
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Publication
34272366 | -
First Author: Garvie CW
Year: 2021
Journal: Nat Commun
Title: Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Volume: 12
Issue: 1
Pages: 4375
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Publication
28460425 | -
First Author: Liu F
Year: 2018
Journal: Cell Biol Int
Title: The Schlafen family: complex roles in different cell types and virus replication.
Volume: 42
Issue: 1
Pages: 2-8
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Protein Coding Gene
MGP_CAROLIEiJ_G0016862 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018836 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018803 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018773 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018776 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018590 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1329004 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019228 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018145 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018561 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018669 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018658 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018739 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018685 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019268 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017915 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018197 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017999 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017706 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:2671205
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2671494
Age: postnatal adult
Specimen Label: brain
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2671205
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2671494
Age: postnatal adult
Specimen Label: heart
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2671205
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2671494
Age: postnatal adult
Specimen Label: kidney
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2671205
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2671494
Age: postnatal adult
Specimen Label: liver
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2671205
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2671494
Age: postnatal adult
Specimen Label: lung
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2671205
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:2671494
Age: postnatal adult
Specimen Label: ovary
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2671205
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2671494
Age: postnatal adult
Specimen Label: spleen
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:2671205
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2671494
Age: postnatal adult
Specimen Label: testis
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:2671205
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2671494
Age: postnatal adult
Specimen Label: thymus
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:2671205
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:2671494
Age: embryonic day 14.5
Specimen Label: E14.5 dpc
Detected: false
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:2671205
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:2671494
Age: embryonic day 10.5
Specimen Label: E10.5 dpc
Detected: false
Specimen Num: 11
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Publication
- | J:85248
   
First Author: Zerrahn J
Year: 2003
Journal: GenBank Submission
Title: Mus musculus strain C57BL/6 schlafen 5 (Slfn5) mRNA, complete cds
Pages: AY261804
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Publication
- | J:85249
   
First Author: Zerrahn J
Year: 2003
Journal: GenBank Submission
Title: Mus musculus strain 129/SvJ schlafen 5 (Slfn5) mRNA, complete cds
Pages: AY261805
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Publication
29528433 | J:258797
First Author: Nakagawa K
Year: 2018
Journal: Int Immunol
Title: Schlafen-8 is essential for lymphatic endothelial cell activation in experimental autoimmune encephalomyelitis.
Volume: 30
Issue: 2
Pages: 69-78
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Publication
9846487 | J:51308
First Author: Schwarz DA
Year: 1998
Journal: Immunity
Title: Schlafen, a new family of growth regulatory genes that affect thymocyte development.
Volume: 9
Issue: 5
Pages: 657-68
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Publication
19619625 | J:152085
First Author: Bustos O
Year: 2009
Journal: Gene
Title: Evolution of the Schlafen genes, a gene family associated with embryonic lethality, meiotic drive, immune processes and orthopoxvirus virulence.
Volume: 447
Issue: 1
Pages: 1-11
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Publication
12383505 | J:79580
First Author: Le Bras S
Year: 2002
Journal: Gene
Title: Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome.
Volume: 296
Issue: 1-2
Pages: 75-86
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Slfn5<em1Smoc> | MGI:7292459
Name: schlafen 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7718268 | C57BL/6JSmoc-Slfn5<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
34710177 | J:313661
First Author: Vomhof-DeKrey EE
Year: 2021
Journal: PLoS One
Title: Vil-Cre specific Schlafen 3 knockout mice exhibit sex-specific differences in intestinal differentiation markers and Schlafen family members expression levels.
Volume: 16
Issue: 10
Pages: e0259195
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Publication
38076659 | J:344682
 
First Author: Vomhof-DeKrey EE
Year: 2023
Journal: Biochem Biophys Rep
Title: Vil-Cre specific Slfn3KO mice exhibit sex-specific differences in lung, stomach, cecum, kidney, and proximal colon differentiation markers and Slfn family members expression levels.
Volume: 36
Pages: 101552
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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