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Search results 1 to 67 out of 67 for Slfnl1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: The Schlafen (SLFN) family includes several mouse and human member genes that have been implicated in important functions, such as the control of cell proliferation, induction of immune responses, and the regulation of viral replication [, , , ]. Mouse and human SLFN proteins are regulated by interferons (IFNs) []. All SLFNs contain an unique Slfn box. SLFN family is comprised of 3 groups, based on the size of the encoded proteins [, , , ]:Group1: Slfn1, Slfn2, and Slfn Like 1.Group2: Slfn3, Slfn4 and Slfn12.Group3: Slfn5, Slfn8-11, Slfn13 and Slfn14.Comparing to group1 proteins, group2 and 3 proteins contain an extra SWADL domain C terminus to the AAA domain. Group3 proteins also possess a large extension C terminus to their SWADL domain. This C-terminal extension is homologous to the superfamily I of DNA/RNA helicases []. It has been proposed that the divergent AAA ATPase domain may function as an RNA-binding domain []. This entry represents SlfnL1 protein. Its function is not clear.
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 410  
Fragment?: false
Publication
First Author: Geserick P
Year: 2004
Journal: Int Immunol
Title: Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif.
Volume: 16
Issue: 10
Pages: 1535-48
Publication
First Author: Mavrommatis E
Year: 2013
Journal: J Interferon Cytokine Res
Title: The schlafen family of proteins and their regulation by interferons.
Volume: 33
Issue: 4
Pages: 206-10
Publication
First Author: Neumann B
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Subcellular localization of the Schlafen protein family.
Volume: 370
Issue: 1
Pages: 62-6
Publication
First Author: Chen J
Year: 2021
Journal: Nat Commun
Title: Structure of PDE3A-SLFN12 complex and structure-based design for a potent apoptosis inducer of tumor cells.
Volume: 12
Issue: 1
Pages: 6204
Publication
First Author: Garvie CW
Year: 2021
Journal: Nat Commun
Title: Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase.
Volume: 12
Issue: 1
Pages: 4375
Publication
First Author: Liu F
Year: 2018
Journal: Cell Biol Int
Title: The Schlafen family: complex roles in different cell types and virus replication.
Volume: 42
Issue: 1
Pages: 2-8
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:3619742
Assay Type: RT-PCR
Annotation Date: 2006-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3619902
Age: postnatal adult
Image: 1
Specimen Label: Kidney
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3619742
Assay Type: RT-PCR
Annotation Date: 2006-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3619902
Age: postnatal adult
Image: 1
Specimen Label: Lung
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:3619742
Assay Type: RT-PCR
Annotation Date: 2006-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3619902
Age: postnatal adult
Image: 1
Specimen Label: Heart
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:3619742
Assay Type: RT-PCR
Annotation Date: 2006-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3619902
Age: postnatal adult
Image: 1
Specimen Label: Liver
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3619742
Assay Type: RT-PCR
Annotation Date: 2006-04-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3619902
Age: postnatal adult
Image: 1
Specimen Label: Testis
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3619742
Assay Type: RT-PCR
Annotation Date: 2006-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:3619902
Age: postnatal adult
Image: 1
Specimen Label: Intestine
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:3619742
Assay Type: RT-PCR
Annotation Date: 2006-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:3619902
Age: postnatal adult
Image: 1
Specimen Label: Muscle
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:3619742
Assay Type: RT-PCR
Annotation Date: 2006-04-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3619902
Age: postnatal adult
Image: 1
Specimen Label: Brain
Detected: false
Specimen Num: 1
Publication
First Author: Park S
Year: 2020
Journal: Biol Reprod
Title: CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity.
Volume: 103
Issue: 2
Pages: 195-204
Publication
First Author: Ferguson DA
Year: 2005
Journal: Gene Expr Patterns
Title: eXPRESSION: an in silico tool to predict patterns of gene expression.
Volume: 5
Issue: 5
Pages: 619-28
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform