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Search results 1 to 100 out of 122 for Slu7

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
10569 | SLU7
Type: gene
Organism: human
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Gene
733806 | slu7
Type: gene
Organism: frog, western clawed
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Gene
479308 | SLU7
Type: gene
Organism: dog, domestic
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Gene
303057 | Slu7
Type: gene
Organism: rat
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Gene
737318 | SLU7
Type: gene
Organism: chimpanzee
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Gene
512318 | SLU7
Type: gene
Organism: cattle
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Gene
416157 | SLU7
Type: gene
Organism: chicken
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Gene
492495 | slu7
Type: gene
Organism: zebrafish
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Gene
696023 | SLU7
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2385598 | Slu7
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24865429 | J:213277
First Author: Elizalde M
Year: 2014
Journal: J Clin Invest
Title: Splicing regulator SLU7 is essential for maintaining liver homeostasis.
Volume: 124
Issue: 7
Pages: 2909-20
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Publication
34170569 | J:345496
First Author: Gárate-Rascón M
Year: 2021
Journal: Hepatology
Title: Splicing Factor SLU7 Prevents Oxidative Stress-Mediated Hepatocyte Nuclear Factor 4α Degradation, Preserving Hepatic Differentiation and Protecting From Liver Damage.
Volume: 74
Issue: 5
Pages: 2791-2807
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Publication
17804646 | J:127368
First Author: Alberstein M
Year: 2007
Journal: RNA
Title: Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing.
Volume: 13
Issue: 11
Pages: 1988-99
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Protein Coding Gene
MGP_CAROLIEiJ_G0016222 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018144 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018108 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017926 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2385598 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018567 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017490 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017899 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018009 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018003 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018081 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018027 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018606 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017271 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017539 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017358 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017063 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:3764968
Assay Type: RNA in situ
Annotation Date: 2007-12-20
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1716128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3764969
Age: postnatal day 15
Specimen Label: not specified
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3764968
Assay Type: RNA in situ
Annotation Date: 2007-12-20
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3764969
Age: postnatal day 15
Specimen Label: 1B2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3764968
Assay Type: RNA in situ
Annotation Date: 2007-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3764969
Age: embryonic day 12.5
Specimen Label: 1C1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3764968
Assay Type: RNA in situ
Annotation Date: 2007-12-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3286620
Stage: TS20
Assay Id: MGI:3764969
Age: embryonic day 12.5
Specimen Label: 1C2
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3764968
Assay Type: RNA in situ
Annotation Date: 2007-12-20
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3764969
Age: postnatal day 15
Specimen Label: 1B2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3764968
Assay Type: RNA in situ
Annotation Date: 2007-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3764969
Age: embryonic day 12.5
Specimen Label: 1C2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3764968
Assay Type: RNA in situ
Annotation Date: 2007-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3764969
Age: postnatal day 30
Specimen Label: 1B1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3764968
Assay Type: RNA in situ
Annotation Date: 2007-12-20
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3764969
Age: postnatal day 15
Specimen Label: 1B2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3764968
Assay Type: RNA in situ
Annotation Date: 2007-12-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3565128
Stage: TS28
Assay Id: MGI:3764969
Age: postnatal day 30
Note: No expression in acinar exocrine cells.
Specimen Label: 1B1
Detected: false
Specimen Num: 1
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Protein
B0QZT9
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
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Protein
Q8BHJ9
Organism: Mus musculus/domesticus
Length: 585  
Fragment?: false
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Protein
Q8R3A1
Organism: Mus musculus/domesticus
Length: 225  
Fragment?: false
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Protein
Z4YM25
Organism: Mus musculus/domesticus
Length: 497  
Fragment?: true
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Publication
24586484 | J:213437
First Author: Storbeck M
Year: 2014
Journal: PLoS One
Title: Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain.
Volume: 9
Issue: 2
Pages: e89020
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Publication
- | J:29126
     
First Author: The Jackson Laboratory DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX Interspecific Backcross BSS and BSB Public Mapping Data
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Publication
9371744 | J:44483
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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UniProt Feature
UniProt Feature
Begin: 2
Description: Pre-mRNA-splicing factor SLU7
Type: chain
End: 585
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Publication
30657957 | J:273846
First Author: Jiménez M
Year: 2019
Journal: Nucleic Acids Res
Title: Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins.
Volume: 47
Issue: 7
Pages: 3450-3466
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Protein Domain
IPR039974 | Splicing_factor_SLU7
Type: Family
Description: The spliceosome, an assembly of snRNAs (U1, U2, U4/U6, and U5) and proteins, catalyses the excision of introns from pre-mRNAs in two successive trans-esterification reactions []. Step 2 depends upon integral spliceosome constituents such as U5 snRNA and Prp8 and non-spliceosomal proteins Prp16, Slu7,Prp18, and Prp22. ATP hydrolysis by the DEAH-box enzyme Prp16 promotes a conformational change in the spliceosome that leads to protection of the 3' splice site from targeted RNase H cleavage. This change, which probably reflects binding of the 3' splice site PyAG in the catalytic centre of the spliceosome, requires the ordered recruitment of Slu7, Prp18, and Prp22 to the spliceosome. There is a close functional relationship between Prp8, Prp18, and Slu7, and Prp18 interacts with Slu7, so that together they recruit Prp22 to the spliceosome. Most members of the family carry a zinc-finger of the CCHC-type; this retains the protein within the nucleus [].
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Protein Domain
IPR021715 | Slu7_dom
Type: Domain
Description: The spliceosome, an assembly of snRNAs (U1, U2, U4/U6, and U5) and proteins, catalyses the excision of introns from pre-mRNAs in two successive trans-esterification reactions []. Step 2 depends upon integral spliceosome constituents such as U5 snRNA and Prp8 and non-spliceosomal proteins Prp16, Slu7, Prp18, and Prp22. ATP hydrolysis by the DEAH-box enzyme Prp16 promotes a conformational change in the spliceosome that leads to protection of the 3' splice site from targeted RNase H cleavage. This change, which probably reflects binding of the 3' splice site PyAG in the catalytic centre of the spliceosome, requires the ordered recruitment of Slu7, Prp18, and Prp22 to the spliceosome. There is a close functional relationship between Prp8, Prp18, and Slu7, and Prp18 interacts with Slu7, so that together they recruit Prp22 to the spliceosome. Most members of the family carry a zinc-finger of the CCHC-type upstream of this domain; this retains the protein within the nucleus [].
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Gene
432205 | slu7.L
Type: gene
Organism: frog, African clawed
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Publication
10197984 | -
First Author: Chua K
Year: 1999
Journal: Genes Dev
Title: Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing.
Volume: 13
Issue: 7
Pages: 841-50
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Publication
15181151 | -
First Author: Shomron N
Year: 2004
Journal: Mol Biol Cell
Title: Splicing factor hSlu7 contains a unique functional domain required to retain the protein within the nucleus.
Volume: 15
Issue: 8
Pages: 3782-95
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Allele
Slu7<+> | MGI:2435854
   
Name: SLU7 splicing factor homolog (S. cerevisiae); wild type
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Allele
Slu7<Gt(XR0469)Wtsi> | MGI:3872327
 
Name: SLU7 splicing factor homolog (S. cerevisiae); gene trap XR0469, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Slu7<Gt(OST205210)Lex> | MGI:4231278
 
Name: SLU7 splicing factor homolog (S. cerevisiae); gene trap OST205210, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Slu7<Gt(XR0575)Wtsi> | MGI:4338260
 
Name: SLU7 splicing factor homolog (S. cerevisiae); gene trap XR0575, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Slu7<Gt(AN0639)Wtsi> | MGI:4345575
 
Name: SLU7 splicing factor homolog (S. cerevisiae); gene trap AN0639, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
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Allele
Slu7<tm1e(KOMP)Wtsi> | MGI:4362622
Name: SLU7 splicing factor homolog (S. cerevisiae); targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Slu7<tm1a(KOMP)Wtsi> | MGI:4363740
Name: SLU7 splicing factor homolog (S. cerevisiae); targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Slu7<em1Cya> | MGI:7586689
Name: SLU7 splicing factor homolog (S. cerevisiae); endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Slu7<em2Cya> | MGI:7796275
Name: SLU7 splicing factor homolog (S. cerevisiae); endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Slu7<em3Cya> | MGI:7796276
Name: SLU7 splicing factor homolog (S. cerevisiae); endonuclease-mediated mutation 3, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:5705891 | C57BL/6N-Slu7<tm1a(KOMP)Wtsi>/Wtsi
Attribute String: coisogenic, targeted mutation
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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