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Search results 1 to 100 out of 219 for Slx4

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0.021s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Wilson JS
Year: 2013
Journal: Cell Rep
Title: Localization-dependent and -independent roles of SLX4 in regulating telomeres.
Volume: 4
Issue: 5
Pages: 853-60
Publication
First Author: Hodskinson MR
Year: 2014
Journal: Mol Cell
Title: Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair.
Volume: 54
Issue: 3
Pages: 472-84
Publication
First Author: Lachaud C
Year: 2014
Journal: J Cell Sci
Title: Distinct functional roles for the two SLX4 ubiquitin-binding UBZ domains mutated in Fanconi anemia.
Volume: 127
Issue: Pt 13
Pages: 2811-7
Gene
Type: gene
Organism: human
Publication      
First Author: Chen Z
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for slim
Publication
First Author: Crossan GP
Year: 2011
Journal: Nat Genet
Title: Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia.
Volume: 43
Issue: 2
Pages: 147-52
Publication
First Author: Castor D
Year: 2013
Journal: Mol Cell
Title: Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases.
Volume: 52
Issue: 2
Pages: 221-33
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Protein
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: false
Publication
First Author: Holloway JK
Year: 2011
Journal: PLoS Genet
Title: Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis.
Volume: 7
Issue: 6
Pages: e1002094
Publication
First Author: Garaycoechea JI
Year: 2012
Journal: Nature
Title: Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.
Volume: 489
Issue: 7417
Pages: 571-5
Publication
First Author: Lachaud C
Year: 2016
Journal: Genes Dev
Title: Karyomegalic interstitial nephritis and DNA damage-induced polyploidy in Fan1 nuclease-defective knock-in mice.
Volume: 30
Issue: 6
Pages: 639-44
Publication
First Author: Thongthip S
Year: 2016
Journal: Genes Dev
Title: Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.
Volume: 30
Issue: 6
Pages: 645-59
Publication
First Author: Vannier JB
Year: 2012
Journal: Cell
Title: RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity.
Volume: 149
Issue: 4
Pages: 795-806
Publication
First Author: Lyndaker AM
Year: 2013
Journal: PLoS Genet
Title: Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance.
Volume: 9
Issue: 2
Pages: e1003320
Publication
First Author: Kim Y
Year: 2011
Journal: Nat Genet
Title: Mutations of the SLX4 gene in Fanconi anemia.
Volume: 43
Issue: 2
Pages: 142-6
Publication
First Author: Alavattam KG
Year: 2016
Journal: Cell Rep
Title: Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.
Volume: 17
Issue: 4
Pages: 1141-1157
Publication
First Author: Perez-Oliva AB
Year: 2015
Journal: EMBO J
Title: USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses.
Volume: 34
Issue: 3
Pages: 326-43
Protein
Organism: Mus musculus/domesticus
Length: 1379  
Fragment?: true
Publication      
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
Publication      
First Author: The Jackson Laboratory DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX Interspecific Backcross BSS and BSB Public Mapping Data
Publication
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Protein
Organism: Mus musculus/domesticus
Length: 1565  
Fragment?: false
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Publication
First Author: Fekairi S
Year: 2009
Journal: Cell
Title: Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.
Volume: 138
Issue: 1
Pages: 78-89
Publication
First Author: Muñoz IM
Year: 2009
Journal: Mol Cell
Title: Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.
Volume: 35
Issue: 1
Pages: 116-27
Publication
First Author: Stoepker C
Year: 2011
Journal: Nat Genet
Title: SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype.
Volume: 43
Issue: 2
Pages: 138-41
Protein Domain
Type: Family
Description: The Slx4 protein is a heteromeric structure-specific endonuclease found from fungi to mammals. Slx4 is a regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination [, ]. The SLX1-SLX4 complex has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs) [, ]. Defects in SLX4 are the cause of Fanconi anemia complementation group P (FANCP), which is a disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia [, ].
UniProt Feature
Begin: 1
Description: Structure-specific endonuclease subunit SLX4
Type: chain
End: 1565
Allele
Name: SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae); endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: Bakker JL
Year: 2013
Journal: Hum Mutat
Title: Analysis of the novel fanconi anemia gene SLX4/FANCP in familial breast cancer cases.
Volume: 34
Issue: 1
Pages: 70-3