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Search results 1 to 100 out of 1397 for Smad2

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Meng XM
Year: 2010
Journal: J Am Soc Nephrol
Title: Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.
Volume: 21
Issue: 9
Pages: 1477-87
Publication
First Author: Martinez GJ
Year: 2010
Journal: J Biol Chem
Title: Smad2 positively regulates the generation of Th17 cells.
Volume: 285
Issue: 38
Pages: 29039-43
Publication
First Author: Itman C
Year: 2009
Journal: Dev Dyn
Title: Developmentally regulated SMAD2 and SMAD3 utilization directs activin signaling outcomes.
Volume: 238
Issue: 7
Pages: 1688-700
Publication
First Author: Cui XM
Year: 2005
Journal: Dev Biol
Title: Overexpression of Smad2 in Tgf-beta3-null mutant mice rescues cleft palate.
Volume: 278
Issue: 1
Pages: 193-202
Publication
First Author: Malhotra N
Year: 2010
Journal: J Biol Chem
Title: SMAD2 is essential for TGF beta-mediated Th17 cell generation.
Volume: 285
Issue: 38
Pages: 29044-8
Publication
First Author: Nomura M
Year: 1998
Journal: Nature
Title: Smad2 role in mesoderm formation, left-right patterning and craniofacial development.
Volume: 393
Issue: 6687
Pages: 786-90
Publication
First Author: Liu Y
Year: 2004
Journal: Dev Biol
Title: Smad2 and Smad3 coordinately regulate craniofacial and endodermal development.
Volume: 270
Issue: 2
Pages: 411-26
Publication
First Author: Dunn NR
Year: 2005
Journal: Genes Dev
Title: Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile.
Volume: 19
Issue: 1
Pages: 152-63
Publication
First Author: Liu Y
Year: 2004
Journal: Genesis
Title: Generation of novel conditional and hypomorphic alleles of the Smad2 gene.
Volume: 40
Issue: 2
Pages: 118-123
Publication
First Author: Bai Y
Year: 2004
Journal: Mol Cell
Title: Itch E3 ligase-mediated regulation of TGF-beta signaling by modulating smad2 phosphorylation.
Volume: 15
Issue: 5
Pages: 825-31
Publication
First Author: Burdette JE
Year: 2007
Journal: Endocrinology
Title: Ovarian epithelial inclusion cysts in chronically superovulated CD1 and Smad2 dominant-negative mice.
Volume: 148
Issue: 8
Pages: 3595-604
Publication
First Author: Pessah M
Year: 2002
Journal: J Biol Chem
Title: c-Jun associates with the oncoprotein Ski and suppresses Smad2 transcriptional activity.
Volume: 277
Issue: 32
Pages: 29094-100
Publication
First Author: Kashiwagi I
Year: 2015
Journal: Immunity
Title: Smad2 and Smad3 Inversely Regulate TGF-β Autoinduction in Clostridium butyricum-Activated Dendritic Cells.
Volume: 43
Issue: 1
Pages: 65-79
GXD Expression  
Probe: MGI:6117786
Assay Type: Immunohistochemistry
Annotation Date: 2018-02-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1736322
Stage: TS22
Assay Id: MGI:6117806
Age: embryonic day 14.5
Image: 2n
Note: Author state prefusion wild-type palatal shelves show no Smad2 activation.
Detected: false
Specimen Num: 8
Publication
First Author: Waldrip WR
Year: 1998
Journal: Cell
Title: Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo.
Volume: 92
Issue: 6
Pages: 797-808
Publication
First Author: Cui XM
Year: 2003
Journal: Dev Dyn
Title: TGF-beta3-dependent SMAD2 phosphorylation and inhibition of MEE proliferation during palatal fusion.
Volume: 227
Issue: 3
Pages: 387-94
Publication
First Author: Hoot KE
Year: 2010
Journal: J Clin Invest
Title: HGF upregulation contributes to angiogenesis in mice with keratinocyte-specific Smad2 deletion.
Volume: 120
Issue: 10
Pages: 3606-16
Publication  
First Author: AlMegbel AM
Year: 2020
Journal: Differentiation
Title: SMAD2 overexpression rescues the TGF-β3 null mutant mice cleft palate by increased apoptosis.
Volume: 111
Pages: 60-69
Publication
First Author: Dick A
Year: 1998
Journal: Dev Dyn
Title: Expression of Smad1 and Smad2 during embryogenesis suggests a role in organ development.
Volume: 211
Issue: 4
Pages: 293-305
Publication
First Author: de Sousa Lopes SM
Year: 2003
Journal: Gene Expr Patterns
Title: Distribution of phosphorylated Smad2 identifies target tissues of TGF beta ligands in mouse development.
Volume: 3
Issue: 3
Pages: 355-60
Publication
First Author: Zhou J
Year: 2002
Journal: Sci China C Life Sci
Title: Establishment of Smad2 conditional gene targeting mice based on the Cre-LoxP system.
Volume: 45
Issue: 2
Pages: 129-37
Publication
First Author: Ito Y
Year: 2001
Journal: Dev Biol
Title: Overexpression of Smad2 reveals its concerted action with Smad4 in regulating TGF-beta-mediated epidermal homeostasis.
Volume: 236
Issue: 1
Pages: 181-94
Publication
First Author: Tannehill-Gregg SH
Year: 2004
Journal: Vet Pathol
Title: The roles of Smad2 and Smad3 in the development of chemically induced skin tumors in mice.
Volume: 41
Issue: 3
Pages: 278-82
Publication  
First Author: Higa R
Year: 2018
Journal: Mol Cell Endocrinol
Title: CD105 maintains the thermogenic program of beige adipocytes by regulating Smad2 signaling.
Volume: 474
Pages: 184-193
Publication
First Author: Wang W
Year: 2016
Journal: PLoS Genet
Title: Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate.
Volume: 12
Issue: 10
Pages: e1006352
Publication    
First Author: Coda DM
Year: 2017
Journal: Elife
Title: Distinct modes of SMAD2 chromatin binding and remodeling shape the transcriptional response to NODAL/Activin signaling.
Volume: 6
Publication
First Author: Wang A
Year: 2013
Journal: J Immunol
Title: Cutting edge: Smad2 and Smad4 regulate TGF-β-mediated Il9 gene expression via EZH2 displacement.
Volume: 191
Issue: 10
Pages: 4908-12
Publication
First Author: Labbé E
Year: 1998
Journal: Mol Cell
Title: Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2.
Volume: 2
Issue: 1
Pages: 109-20
Publication  
First Author: Dupuis LE
Year: 2013
Journal: J Mol Cell Cardiol
Title: Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves.
Volume: 60
Pages: 50-9
Publication
First Author: Ju W
Year: 2006
Journal: Mol Cell Biol
Title: Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation.
Volume: 26
Issue: 2
Pages: 654-67
Publication
First Author: Duan WJ
Year: 2014
Journal: Am J Pathol
Title: Opposing roles for Smad2 and Smad3 in peritoneal fibrosis in vivo and in vitro.
Volume: 184
Issue: 8
Pages: 2275-84
Publication
First Author: Hoot KE
Year: 2008
Journal: J Clin Invest
Title: Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression.
Volume: 118
Issue: 8
Pages: 2722-32
Publication
First Author: Feldmann K
Year: 2002
Journal: Eur J Immunol
Title: Resistance to TGF-beta1-mediated growth inhibition correlates with sustained Smad2 phosphorylation in primary murine splenocytes.
Volume: 32
Issue: 5
Pages: 1393-402
Publication
First Author: Ito Y
Year: 2001
Journal: J Biol Chem
Title: Antagonistic effects of Smad2 versus Smad7 are sensitive to their expression level during tooth development.
Volume: 276
Issue: 47
Pages: 44163-72
Publication  
First Author: Wang Y
Year: 2016
Journal: Mol Cell Endocrinol
Title: Endogenous inhibins regulate steroidogenesis in mouse TM3 Leydig cells by altering SMAD2 signalling.
Volume: 436
Pages: 68-77
Publication
First Author: Li Q
Year: 2008
Journal: Mol Cell Biol
Title: Redundant roles of SMAD2 and SMAD3 in ovarian granulosa cells in vivo.
Volume: 28
Issue: 23
Pages: 7001-11
Publication
First Author: Dunn NR
Year: 2004
Journal: Development
Title: Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo.
Volume: 131
Issue: 8
Pages: 1717-28
Publication
First Author: Xie WB
Year: 2013
Journal: Circ Res
Title: Smad2 and myocardin-related transcription factor B cooperatively regulate vascular smooth muscle differentiation from neural crest cells.
Volume: 113
Issue: 8
Pages: e76-86
Publication
First Author: Tu AW
Year: 2007
Journal: J Biol Chem
Title: Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response.
Volume: 282
Issue: 29
Pages: 21187-96
Publication
First Author: Ueberham U
Year: 2009
Journal: Int J Dev Neurosci
Title: Smad2 isoforms are differentially expressed during mouse brain development and aging.
Volume: 27
Issue: 5
Pages: 501-10
Publication
First Author: Hamamoto T
Year: 2002
Journal: Cancer Res
Title: Compound disruption of smad2 accelerates malignant progression of intestinal tumors in apc knockout mice.
Volume: 62
Issue: 20
Pages: 5955-61
Publication
First Author: Osaki M
Year: 1999
Journal: Endocr J
Title: cDNA cloning and chromosomal mapping of rat Smad2 and Smad4 and their expression in cultured rat articular chondrocytes.
Volume: 46
Issue: 5
Pages: 695-701
Publication
First Author: Klein J
Year: 2006
Journal: J Immunol
Title: B cell-specific deficiency for Smad2 in vivo leads to defects in TGF-beta-directed IgA switching and changes in B cell fate.
Volume: 176
Issue: 4
Pages: 2389-96
Publication
First Author: Takaku K
Year: 2002
Journal: Cancer Res
Title: No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in Apc(delta716) knockout mice.
Volume: 62
Issue: 16
Pages: 4558-61
Publication
First Author: Wang L
Year: 2011
Journal: J Biol Chem
Title: Smad2 protein disruption in the central nervous system leads to aberrant cerebellar development and early postnatal ataxia in mice.
Volume: 286
Issue: 21
Pages: 18766-74
Publication
First Author: Fortin J
Year: 2014
Journal: FASEB J
Title: Follicle-stimulating hormone synthesis and fertility are intact in mice lacking SMAD3 DNA binding activity and SMAD2 in gonadotrope cells.
Volume: 28
Issue: 3
Pages: 1474-85
Publication
First Author: Sugiyama Y
Year: 2012
Journal: Int Immunol
Title: Smad2 and Smad3 are redundantly essential for the suppression of iNOS synthesis in macrophages by regulating IRF3 and STAT1 pathways.
Volume: 24
Issue: 4
Pages: 253-65
Publication
First Author: Devereux TR
Year: 1997
Journal: Carcinogenesis
Title: Smad4 (homolog of human DPC4) and Smad2 (homolog of human JV18-1): candidates for murine lung tumor resistance and suppressor genes.
Volume: 18
Issue: 9
Pages: 1751-5
Publication
First Author: Yamamoto M
Year: 2009
Journal: J Cell Biol
Title: Antagonism between Smad1 and Smad2 signaling determines the site of distal visceral endoderm formation in the mouse embryo.
Volume: 184
Issue: 2
Pages: 323-34
Publication
First Author: Wu Q
Year: 2015
Journal: Development
Title: SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice.
Volume: 142
Issue: 3
Pages: 575-86
Publication
First Author: Yang J
Year: 2014
Journal: Cardiovasc Res
Title: Epicardial calcineurin-NFAT signals through Smad2 to direct coronary smooth muscle cell and arterial wall development.
Volume: 101
Issue: 1
Pages: 120-9
Publication
First Author: Nomura M
Year: 2014
Journal: Diabetologia
Title: SMAD2 disruption in mouse pancreatic beta cells leads to islet hyperplasia and impaired insulin secretion due to the attenuation of ATP-sensitive K+ channel activity.
Volume: 57
Issue: 1
Pages: 157-66
Publication
First Author: Vivian JL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: An allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N- nitrosourea-mutagenized mouse embryonic stem cells.
Volume: 99
Issue: 24
Pages: 15542-7
Publication
First Author: Goto Y
Year: 2007
Journal: Dev Dyn
Title: Genetic interactions between activin type IIB receptor and Smad2 genes in asymmetrical patterning of the thoracic organs and the development of pancreas islets.
Volume: 236
Issue: 10
Pages: 2865-74
Allele
Name: SMAD family member 2; targeted mutation 5, Elizabeth Robertson
Allele Type: Targeted
Attribute String: Inserted expressed sequence
Publication categories: ProxyCollection
Publication
First Author: Kriseman M
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Uterine double-conditional inactivation of Smad2 and Smad3 in mice causes endometrial dysregulation, infertility, and uterine cancer.
Volume: 116
Issue: 9
Pages: 3873-3882
Publication
First Author: Quartuccio SM
Year: 2013
Journal: PLoS One
Title: Conditional inactivation of p53 in mouse ovarian surface epithelium does not alter MIS driven Smad2-dominant negative epithelium-lined inclusion cysts or teratomas.
Volume: 8
Issue: 5
Pages: e65067
Strain
Attribute String: mutant stock, targeted mutation
Publication
First Author: Carvalho RL
Year: 2007
Journal: J Cell Sci
Title: Compensatory signalling induced in the yolk sac vasculature by deletion of TGFbeta receptors in mice.
Volume: 120
Issue: Pt 24
Pages: 4269-77
Strain
Attribute String: targeted mutation, mutant stock
Publication
First Author: Yang X
Year: 2011
Journal: J Biol Chem
Title: Delayed re-epithelialization in Ppm1a gene-deficient mice is mediated by enhanced activation of Smad2.
Volume: 286
Issue: 49
Pages: 42267-73
Publication
First Author: Rosendahl A
Year: 2003
Journal: Int Immunol
Title: Transforming growth factor-beta- and Activin-Smad signaling pathways are activated at distinct maturation stages of the thymopoeisis.
Volume: 15
Issue: 12
Pages: 1401-14
Publication
First Author: Jiang H
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Inhibition of lncRNA PFRL prevents pulmonary fibrosis by disrupting the miR-26a/smad2 loop.
Volume: 315
Issue: 4
Pages: L563-L575
Publication
First Author: Xiao X
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7.
Volume: 111
Issue: 13
Pages: E1211-20
Publication
First Author: Heyer J
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis.
Volume: 96
Issue: 22
Pages: 12595-600
Publication
First Author: Ring C
Year: 2002
Journal: Genes Dev
Title: The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling.
Volume: 16
Issue: 7
Pages: 820-35
Publication
First Author: Zhang Y
Year: 2017
Journal: Cell Rep
Title: Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing.
Volume: 18
Issue: 2
Pages: 545-556
Publication
First Author: Chung AC
Year: 2010
Journal: J Am Soc Nephrol
Title: miR-192 mediates TGF-beta/Smad3-driven renal fibrosis.
Volume: 21
Issue: 8
Pages: 1317-25
Publication
First Author: Weinstein M
Year: 2000
Journal: Cytokine Growth Factor Rev
Title: Functions of mammalian Smad genes as revealed by targeted gene disruption in mice.
Volume: 11
Issue: 1-2
Pages: 49-58
Publication
First Author: Miura S
Year: 2000
Journal: Mol Cell Biol
Title: Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.
Volume: 20
Issue: 24
Pages: 9346-55
Publication  
First Author: Yoon JH
Year: 2015
Journal: Nat Commun
Title: Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation.
Volume: 6
Pages: 7600
Publication
First Author: Lee BH
Year: 2007
Journal: J Biol Chem
Title: Biological cross-talk between WNK1 and the transforming growth factor beta-Smad signaling pathway.
Volume: 282
Issue: 25
Pages: 17985-96
Publication
First Author: Ichiyama K
Year: 2011
Journal: Immunity
Title: Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin.
Volume: 34
Issue: 5
Pages: 741-54
Publication
First Author: Zhang L
Year: 2013
Journal: Mol Cell
Title: TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.
Volume: 51
Issue: 5
Pages: 559-72
Publication
First Author: Lin AH
Year: 2005
Journal: J Immunol
Title: Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury.
Volume: 175
Issue: 1
Pages: 547-54
Publication
First Author: Ito Y
Year: 2002
Journal: Dev Dyn
Title: Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development.
Volume: 224
Issue: 1
Pages: 69-78
Publication
First Author: Tremblay KD
Year: 2000
Journal: Development
Title: Formation of the definitive endoderm in mouse is a Smad2-dependent process.
Volume: 127
Issue: 14
Pages: 3079-90
Publication
First Author: Ueberham U
Year: 2014
Journal: Neuropathol Appl Neurobiol
Title: Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease.
Volume: 40
Issue: 7
Pages: 815-32
Publication
First Author: Lee CH
Year: 2003
Journal: Exp Cell Res
Title: Nordihydroguaiaretic acid, an antioxidant, inhibits transforming growth factor-beta activity through the inhibition of Smad signaling pathway.
Volume: 289
Issue: 2
Pages: 335-41
Publication
First Author: Weinstein M
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2.
Volume: 95
Issue: 16
Pages: 9378-83
Publication
First Author: Wilkinson DS
Year: 2005
Journal: Mol Cell Biol
Title: A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene.
Volume: 25
Issue: 3
Pages: 1200-12
Publication
First Author: Londesborough A
Year: 2008
Journal: Development
Title: LKB1 in endothelial cells is required for angiogenesis and TGFbeta-mediated vascular smooth muscle cell recruitment.
Volume: 135
Issue: 13
Pages: 2331-8
Publication
First Author: Cooley BC
Year: 2014
Journal: Sci Transl Med
Title: TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling.
Volume: 6
Issue: 227
Pages: 227ra34
Publication
First Author: Mishra B
Year: 2004
Journal: Liver Int
Title: Loss of cooperative function of transforming growth factor-beta signaling proteins, smad3 with embryonic liver fodrin, a beta-spectrin, in primary biliary cirrhosis.
Volume: 24
Issue: 6
Pages: 637-45
Publication
First Author: Melchior-Becker A
Year: 2011
Journal: J Biol Chem
Title: Deficiency of biglycan causes cardiac fibroblasts to differentiate into a myofibroblast phenotype.
Volume: 286
Issue: 19
Pages: 17365-75
Publication
First Author: Chang HM
Year: 2014
Journal: PLoS One
Title: The FYVE domain of Smad Anchor for Receptor Activation (SARA) is required to prevent skin carcinogenesis, but not in mouse development.
Volume: 9
Issue: 8
Pages: e105299
Publication
First Author: Chen S
Year: 2004
Journal: Circ Res
Title: Transforming growth factor-beta-induced differentiation of smooth muscle from a neural crest stem cell line.
Volume: 94
Issue: 9
Pages: 1195-202
Publication
First Author: Das R
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Upregulation of mitochondrial Nox4 mediates TGF-β-induced apoptosis in cultured mouse podocytes.
Volume: 306
Issue: 2
Pages: F155-67
Publication
First Author: Mohan S
Year: 2008
Journal: Bone
Title: A chemical mutagenesis screen to identify modifier genes that interact with growth hormone and TGF-beta signaling pathways.
Volume: 42
Issue: 2
Pages: 388-95
Publication
First Author: Senft AD
Year: 2019
Journal: Nat Commun
Title: Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse.
Volume: 10
Issue: 1
Pages: 1089
Publication  
First Author: Wu C
Year: 2015
Journal: Nat Commun
Title: Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis.
Volume: 6
Pages: 7531
Publication
First Author: Weinstein M
Year: 2001
Journal: Mol Cell Biol
Title: Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development.
Volume: 21
Issue: 15
Pages: 5122-31
Publication
First Author: Liu B
Year: 1999
Journal: Mol Cell Biol
Title: FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor beta signals.
Volume: 19
Issue: 1
Pages: 424-30
Publication
First Author: Ichise T
Year: 2014
Journal: J Cell Sci
Title: FGF2-induced Ras-MAPK signalling maintains lymphatic endothelial cell identity by upregulating endothelial-cell-specific gene expression and suppressing TGFβ signalling through Smad2.
Volume: 127
Issue: Pt 4
Pages: 845-57
Publication
First Author: Tamiya T
Year: 2013
Journal: J Immunol
Title: Smad2/3 and IRF4 play a cooperative role in IL-9-producing T cell induction.
Volume: 191
Issue: 5
Pages: 2360-71
Publication
First Author: Terakawa J
Year: 2016
Journal: Mol Endocrinol
Title: FGFR2IIIb-MAPK Activity Is Required for Epithelial Cell Fate Decision in the Lower Müllerian Duct.
Volume: 30
Issue: 7
Pages: 783-95