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Search results 1 to 100 out of 1588 for Smad5

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
4090 | SMAD5
Type: gene
Organism: human
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Gene
481520 | SMAD5
Type: gene
Organism: dog, domestic
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Gene
768050 | SMAD5
Type: gene
Organism: cattle
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Gene
395679 | SMAD5
Type: gene
Organism: chicken
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Gene
30641 | smad5
Type: gene
Organism: zebrafish
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Gene
712645 | SMAD5
Type: gene
Organism: macaque, rhesus
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Gene
59328 | Smad5
Type: gene
Organism: rat
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Gene
745633 | SMAD5
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1328787 | Smad5
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
9597 | SMAD5-AS1
Type: gene
Organism: human
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GXD Expression
GXD Expression
Probe: MGI:1333122
Assay Type: RNA in situ
Annotation Date: 1999-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610513
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:1334498
Age: embryonic day 8.5
Image: 4. Smad5
Note: Expression is detected in the myocardiac progenitor cells.
Specimen Label: 4. Smad5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1333122
Assay Type: RNA in situ
Annotation Date: 1999-04-20
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1604213
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:1334498
Age: embryonic day 8.5
Image: 4. Smad5
Note: Expression is very high in aggregates of cells on the amnion. Expression detected in the allantois.
Specimen Label: 4. Smad5
Detected: true
Specimen Num: 2
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Publication
16896158 | J:140441
First Author: Singbrant S
Year: 2006
Journal: Blood
Title: Smad5 is dispensable for adult murine hematopoiesis.
Volume: 108
Issue: 12
Pages: 3707-12
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Publication
19067324 | J:162604
First Author: Yang SM
Year: 2009
Journal: Dev Neurobiol
Title: Smad5 haploinsufficiency leads to hair cell and hearing loss.
Volume: 69
Issue: 2-3
Pages: 153-61
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Publication
10677256 | J:60975
First Author: Chang H
Year: 2000
Journal: Dev Biol
Title: Smad5 is essential for left-right asymmetry in mice.
Volume: 219
Issue: 1
Pages: 71-8
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Publication
11404080 | J:70069
First Author: Chang H
Year: 2001
Journal: Mech Dev
Title: Smad5 is required for mouse primordial germ cell development.
Volume: 104
Issue: 1-2
Pages: 61-7
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Publication
15878335 | J:105104
First Author: Sun Y
Year: 2005
Journal: Exp Cell Res
Title: Disruption of Smad5 gene induces mitochondria-dependent apoptosis in cardiomyocytes.
Volume: 306
Issue: 1
Pages: 85-93
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Publication
17456754 | J:121072
First Author: Umans L
Year: 2007
Journal: Am J Pathol
Title: Inactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasis.
Volume: 170
Issue: 5
Pages: 1460-72
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Publication
9288787 | J:42808
First Author: Hejlik DP
Year: 1997
Journal: Cancer Res
Title: Localization of SMAD5 and its evaluation as a candidate myeloid tumor suppressor.
Volume: 57
Issue: 17
Pages: 3779-83
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Publication
16765933 | J:119296
First Author: Arnold SJ
Year: 2006
Journal: Dev Biol
Title: Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo.
Volume: 296
Issue: 1
Pages: 104-18
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Publication
10079226 | J:53293
First Author: Chang H
Year: 1999
Journal: Development
Title: Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects.
Volume: 126
Issue: 8
Pages: 1631-42
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Publication
27426726 | J:235942
First Author: Fang T
Year: 2016
Journal: Exp Cell Res
Title: miR-106b-5p and miR-17-5p suppress osteogenic differentiation by targeting Smad5 and inhibit bone formation.
Volume: 347
Issue: 1
Pages: 74-82
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Publication
20133617 | J:157573
First Author: Rai D
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis.
Volume: 107
Issue: 7
Pages: 3111-6
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Publication
12393578 | J:81128
First Author: Liu B
Year: 2003
Journal: Blood
Title: Disruption of Smad5 gene leads to enhanced proliferation of high-proliferative potential precursors during embryonic hematopoiesis.
Volume: 101
Issue: 1
Pages: 124-33
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Publication
14502571 | J:86157
First Author: Umans L
Year: 2003
Journal: Genesis
Title: Generation of a floxed allele of Smad5 for cre-mediated conditional knockout in the mouse.
Volume: 37
Issue: 1
Pages: 5-11
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Publication
25870111 | J:316445
First Author: Marks-Bluth J
Year: 2015
Journal: Mol Cell Biol
Title: SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development.
Volume: 35
Issue: 12
Pages: 2165-72
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Publication
16887830 | J:112229
First Author: Bosman EA
Year: 2006
Journal: Development
Title: Smad5 determines murine amnion fate through the control of bone morphogenetic protein expression and signalling levels.
Volume: 133
Issue: 17
Pages: 3399-409
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Publication
21212325 | J:171163
First Author: Allaire JM
Year: 2011
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Loss of Smad5 leads to the disassembly of the apical junctional complex and increased susceptibility to experimental colitis.
Volume: 300
Issue: 4
Pages: G586-97
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GXD Expression
GXD Expression
   
Probe: MGI:6183814
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191343
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Smad5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6183814
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191343
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Smad5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6183814
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191343
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Smad5
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6183814
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191343
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Smad5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6183814
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191343
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Smad5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6183814
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191343
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Smad5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6183814
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191343
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Smad5
Detected: true
Specimen Num: 6
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Publication
14711801 | J:97483
First Author: Shi W
Year: 2004
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Overexpression of Smurf1 negatively regulates mouse embryonic lung branching morphogenesis by specifically reducing Smad1 and Smad5 proteins.
Volume: 286
Issue: 2
Pages: L293-300
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Publication
19224984 | J:147287
First Author: Retting KN
Year: 2009
Journal: Development
Title: BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation.
Volume: 136
Issue: 7
Pages: 1093-104
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Publication
17967875 | J:128934
First Author: Pangas SA
Year: 2008
Journal: Mol Cell Biol
Title: Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice.
Volume: 28
Issue: 1
Pages: 248-57
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Publication
11451567 | J:70581
First Author: Zwijsen A
Year: 2001
Journal: Mol Cell Endocrinol
Title: Transforming growth factor beta signalling in vitro and in vivo: activin ligand-receptor interaction, Smad5 in vasculogenesis, and repression of target genes by the deltaEF1/ZEB-related SIP1 in the vertebrate embryo.
Volume: 180
Issue: 1-2
Pages: 13-24
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Publication
18060457 | J:128616
First Author: Hegde S
Year: 2007
Journal: Mamm Genome
Title: An intronic sequence mutated in flexed-tail mice regulates splicing of Smad5.
Volume: 18
Issue: 12
Pages: 852-60
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Publication
15591122 | J:98445
First Author: Lenox LE
Year: 2005
Journal: Blood
Title: BMP4 and Madh5 regulate the erythroid response to acute anemia.
Volume: 105
Issue: 7
Pages: 2741-8
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Publication
32210087 | J:304666
 
First Author: Benn A
Year: 2020
Journal: Biomolecules
Title: BMP-SMAD1/5 Signaling Regulates Retinal Vascular Development.
Volume: 10
Issue: 3
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Publication
24136167 | J:331338
First Author: Jiang D
Year: 2014
Journal: Blood
Title: MicroRNA-155 controls RB phosphorylation in normal and malignant B lymphocytes via the noncanonical TGF-β1/SMAD5 signaling module.
Volume: 123
Issue: 1
Pages: 86-93
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Publication
18615729 | J:138587
First Author: Monteiro RM
Year: 2008
Journal: Genesis
Title: Real time monitoring of BMP Smads transcriptional activity during mouse development.
Volume: 46
Issue: 7
Pages: 335-46
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Publication
10708952 | J:61302
First Author: Weinstein M
Year: 2000
Journal: Cytokine Growth Factor Rev
Title: Functions of mammalian Smad genes as revealed by targeted gene disruption in mice.
Volume: 11
Issue: 1-2
Pages: 49-58
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Publication
20371744 | J:161541
First Author: Singbrant S
Year: 2010
Journal: Blood
Title: Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.
Volume: 115
Issue: 23
Pages: 4689-98
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Publication
10079220 | J:53289
First Author: Yang X
Year: 1999
Journal: Development
Title: Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5.
Volume: 126
Issue: 8
Pages: 1571-80
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Publication
24023003 | J:206767
First Author: Kandyba E
Year: 2014
Journal: Stem Cells
Title: Smad1 and 5 but not Smad8 establish stem cell quiescence which is critical to transform the premature hair follicle during morphogenesis toward the postnatal state.
Volume: 32
Issue: 2
Pages: 534-47
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Publication
25165122 | J:218309
First Author: Mansouri-Attia N
Year: 2014
Journal: Biol Reprod
Title: Soy promotes juvenile granulosa cell tumor development in mice and in the human granulosa cell tumor-derived COV434 cell line.
Volume: 91
Issue: 4
Pages: 100
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Publication
21270055 | J:169137
First Author: Xu B
Year: 2011
Journal: Development
Title: Smad1 and its target gene Wif1 coordinate BMP and Wnt signaling activities to regulate fetal lung development.
Volume: 138
Issue: 5
Pages: 925-35
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Publication
21239498 | J:170631
First Author: Hisa I
Year: 2011
Journal: J Biol Chem
Title: Parathyroid hormone-responsive Smad3-related factor, Tmem119, promotes osteoblast differentiation and interacts with the bone morphogenetic protein-Runx2 pathway.
Volume: 286
Issue: 11
Pages: 9787-96
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Publication
28438754 | J:243338
First Author: Wang CY
Year: 2017
Journal: Blood
Title: Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice.
Volume: 130
Issue: 1
Pages: 73-83
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Publication
21297990 | J:180944
First Author: Keller B
Year: 2011
Journal: PLoS One
Title: Interaction of TGFβ and BMP signaling pathways during chondrogenesis.
Volume: 6
Issue: 1
Pages: e16421
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Publication
23203803 | J:283477
First Author: Chen D
Year: 2013
Journal: J Cell Sci
Title: The transcriptional co-regulator Jab1 is crucial for chondrocyte differentiation in vivo.
Volume: 126
Issue: Pt 1
Pages: 234-43
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Publication
20689554 | J:186333
First Author: Ono Y
Year: 2011
Journal: Cell Death Differ
Title: BMP signalling permits population expansion by preventing premature myogenic differentiation in muscle satellite cells.
Volume: 18
Issue: 2
Pages: 222-34
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Publication
22964636 | J:199979
First Author: Tripurani SK
Year: 2013
Journal: Oncogene
Title: BMP-specific SMADs function as novel repressors of PDGFA and modulate its expression in ovarian granulosa cells and tumors.
Volume: 32
Issue: 33
Pages: 3877-85
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Publication
19252488 | J:151027
First Author: Meynard D
Year: 2009
Journal: Nat Genet
Title: Lack of the bone morphogenetic protein BMP6 induces massive iron overload.
Volume: 41
Issue: 4
Pages: 478-81
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Publication
29884675 | J:263987
 
First Author: Dobreva MP
Year: 2018
Journal: Development
Title: Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling.
Volume: 145
Issue: 13
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Publication
12857787 | J:85098
First Author: Pellegrini M
Year: 2003
Journal: J Cell Sci
Title: Developmental expression of BMP4/ALK3/SMAD5 signaling pathway in the mouse testis: a potential role of BMP4 in spermatogonia differentiation.
Volume: 116
Issue: Pt 16
Pages: 3363-72
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Publication
16087734 | J:100763
First Author: Williams TM
Year: 2005
Journal: Nucleic Acids Res
Title: Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability.
Volume: 33
Issue: 14
Pages: 4475-84
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Publication
22609550 | J:185870
First Author: Hazen VM
Year: 2012
Journal: Dev Biol
Title: BMP receptor-activated Smads confer diverse functions during the development of the dorsal spinal cord.
Volume: 367
Issue: 2
Pages: 216-27
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Publication
19661464 | J:169971
First Author: Singh R
Year: 2009
Journal: Circ Res
Title: Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canal.
Volume: 105
Issue: 5
Pages: 442-52
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Publication
22240098 | J:182768
First Author: Wong YL
Year: 2012
Journal: Dev Biol
Title: Smad1/Smad5 signaling in limb ectoderm functions redundantly and is required for interdigital programmed cell death.
Volume: 363
Issue: 1
Pages: 247-57
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Publication
23459943 | J:203750
First Author: Tong KK
Year: 2013
Journal: Mol Cell Biol
Title: Common partner Smad-independent canonical bone morphogenetic protein signaling in the specification process of the anterior rhombic lip during cerebellum development.
Volume: 33
Issue: 10
Pages: 1925-37
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Publication
22912414 | J:187710
First Author: Pereira PN
Year: 2012
Journal: Development
Title: Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion.
Volume: 139
Issue: 18
Pages: 3343-54
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Publication
19717565 | J:156972
First Author: De Rosa L
Year: 2009
Journal: J Biol Chem
Title: p63 Suppresses non-epidermal lineage markers in a bone morphogenetic protein-dependent manner via repression of Smad7.
Volume: 284
Issue: 44
Pages: 30574-82
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Publication
35383354 | J:324161
 
First Author: Tang S
Year: 2022
Journal: Endocrinology
Title: BMP/SMAD1/5 Signaling in the Endometrial Epithelium Is Essential for Receptivity and Early Pregnancy.
Volume: 163
Issue: 5
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Publication
32541003 | J:291493
 
First Author: Najas S
Year: 2020
Journal: Development
Title: A SMAD1/5-YAP signalling module drives radial glia self-amplification and growth of the developing cerebral cortex.
Volume: 147
Issue: 13
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Publication
27068110 | J:235682
First Author: Villacorte M
Year: 2016
Journal: Development
Title: Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.
Volume: 143
Issue: 11
Pages: 1958-70
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Publication
23620745 | J:200638
First Author: Islam SS
Year: 2013
Journal: PLoS One
Title: Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis.
Volume: 8
Issue: 4
Pages: e61340
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Publication
11566864 | J:71998
First Author: Tremblay KD
Year: 2001
Journal: Development
Title: Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation.
Volume: 128
Issue: 18
Pages: 3609-21
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Protein Coding Gene
MGP_CAROLIEiJ_G0018589 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020577 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020555 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020573 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020372 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1328787 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021007 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019886 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020332 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020455 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020434 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020531 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020463 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021050 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019642 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019948 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019653 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019469 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
11729207 | J:242478
First Author: Korchynskyi O
Year: 2002
Journal: J Biol Chem
Title: Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter.
Volume: 277
Issue: 7
Pages: 4883-91
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Publication
11401485 | J:68636
First Author: Hsu HJ
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Ectopic expression of negative ARNT2 factor disrupts fish development.
Volume: 282
Issue: 2
Pages: 487-92
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Publication
14739937 | J:87878
First Author: Itoh F
Year: 2004
Journal: EMBO J
Title: Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells.
Volume: 23
Issue: 3
Pages: 541-51
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GXD Expression
GXD Expression
     
Probe: MGI:3527810
Assay Type: RT-PCR
Annotation Date: 2005-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737320
Stage: TS20
Assay Id: MGI:3527846
Age: embryonic day 12.0
Specimen Label: E12
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3527810
Assay Type: RT-PCR
Annotation Date: 2005-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737323
Stage: TS23
Assay Id: MGI:3527846
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3527810
Assay Type: RT-PCR
Annotation Date: 2005-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:3527846
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3527810
Assay Type: RT-PCR
Annotation Date: 2005-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737327
Stage: TS27
Assay Id: MGI:3527846
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3527810
Assay Type: RT-PCR
Annotation Date: 2005-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3527846
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3527810
Assay Type: RT-PCR
Annotation Date: 2005-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3527846
Age: postnatal adult
Specimen Label: AD
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:2155385
Assay Type: Western blot
Annotation Date: 2006-12-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:3689438
Age: embryonic day 9.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
•
•
•
•
•




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