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Search results 1 to 100 out of 513 for Smad7

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Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:7576830
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640616
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:7576858
Age: embryonic day 10.0
Image: 6B Smad7 WT
Specimen Label: 6B Smad7 WT
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7576830
Assay Type: RNA in situ
Annotation Date: 2024-01-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640816
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:7576858
Age: embryonic day 10.0
Image: 6B Smad7 delta/deltac
Note: Authors report spatial alterations of expression in anterior mesenchyme.
Specimen Label: 6B Smad7 delta/deltac
Detected: true
Specimen Num: 2
Publication
First Author: Kollias HD
Year: 2006
Journal: Mol Cell Biol
Title: Smad7 promotes and enhances skeletal muscle differentiation.
Volume: 26
Issue: 16
Pages: 6248-60
Publication
First Author: Blank U
Year: 2006
Journal: Blood
Title: Smad7 promotes self-renewal of hematopoietic stem cells.
Volume: 108
Issue: 13
Pages: 4246-54
Publication
First Author: Miyake T
Year: 2010
Journal: Mol Cell Biol
Title: Nuclear function of Smad7 promotes myogenesis.
Volume: 30
Issue: 3
Pages: 722-35
Publication
First Author: Lukas D
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: TGF-β inhibitor Smad7 regulates dendritic cell-induced autoimmunity.
Volume: 114
Issue: 8
Pages: E1480-E1489
Publication
First Author: Rizzo A
Year: 2011
Journal: Cancer Res
Title: Smad7 expression in T cells prevents colitis-associated cancer.
Volume: 71
Issue: 24
Pages: 7423-32
Publication
First Author: Reynolds LE
Year: 2008
Journal: J Clin Invest
Title: alpha3beta1 integrin-controlled Smad7 regulates reepithelialization during wound healing in mice.
Volume: 118
Issue: 3
Pages: 965-74
Publication
First Author: Cohen TV
Year: 2015
Journal: J Physiol
Title: Genetic disruption of Smad7 impairs skeletal muscle growth and regeneration.
Volume: 593
Issue: 11
Pages: 2479-97
Publication
First Author: Garo LP
Year: 2019
Journal: Cell Rep
Title: Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity.
Volume: 28
Issue: 13
Pages: 3353-3366.e5
Publication  
First Author: Zhao F
Year: 2020
Journal: Cells
Title: Mesenchymal MACF1 Facilitates SMAD7 Nuclear Translocation to Drive Bone Formation.
Volume: 9
Issue: 3
Publication
First Author: Estrada KD
Year: 2013
Journal: Dev Biol
Title: Smad7 regulates terminal maturation of chondrocytes in the growth plate.
Volume: 382
Issue: 2
Pages: 375-84
Publication
First Author: Liu Z
Year: 2019
Journal: J Dent Res
Title: Smad7 Regulates Dental Epithelial Proliferation during Tooth Development.
Volume: 98
Issue: 12
Pages: 1376-1385
Publication
First Author: Nagarajan RP
Year: 1999
Journal: J Biol Chem
Title: Regulation of Smad7 promoter by direct association with Smad3 and Smad4.
Volume: 274
Issue: 47
Pages: 33412-8
Publication
First Author: He W
Year: 2002
Journal: EMBO J
Title: Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues.
Volume: 21
Issue: 11
Pages: 2580-90
Publication
First Author: Mleczko-Sanecka K
Year: 2010
Journal: Blood
Title: SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression.
Volume: 115
Issue: 13
Pages: 2657-65
Publication
First Author: Han G
Year: 2011
Journal: Am J Pathol
Title: Temporal smad7 transgene induction in mouse epidermis accelerates skin wound healing.
Volume: 179
Issue: 4
Pages: 1768-79
Publication
First Author: Tang S
Year: 2010
Journal: Dev Biol
Title: Trigenic neural crest-restricted Smad7 over-expression results in congenital craniofacial and cardiovascular defects.
Volume: 344
Issue: 1
Pages: 233-47
Publication
First Author: Wang J
Year: 2013
Journal: J Pathol
Title: Inhibitory role of Smad7 in hepatocarcinogenesis in mice and in vitro.
Volume: 230
Issue: 4
Pages: 441-52
Publication
First Author: Chen HY
Year: 2011
Journal: Diabetes
Title: The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential.
Volume: 60
Issue: 2
Pages: 590-601
Publication
First Author: Li J
Year: 2022
Journal: FASEB J
Title: The role of endogenous Smad7 in regulating macrophage phenotype following myocardial infarction.
Volume: 36
Issue: 7
Pages: e22400
Publication
First Author: Tang Y
Year: 2008
Journal: J Biol Chem
Title: Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion.
Volume: 283
Issue: 35
Pages: 23956-63
Publication
First Author: Nakao A
Year: 1999
Journal: J Clin Invest
Title: Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice.
Volume: 104
Issue: 1
Pages: 5-11
Publication
First Author: Liu Z
Year: 2017
Journal: Hypertension
Title: Deletion of Angiotensin-Converting Enzyme-2 Promotes Hypertensive Nephropathy by Targeting Smad7 for Ubiquitin Degradation.
Volume: 70
Issue: 4
Pages: 822-830
Publication
First Author: Fantini MC
Year: 2009
Journal: Gastroenterology
Title: Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.
Volume: 136
Issue: 4
Pages: 1308-16, e1-3
Publication
First Author: Dooley S
Year: 2008
Journal: Gastroenterology
Title: Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage.
Volume: 135
Issue: 2
Pages: 642-59
GXD Expression    
Probe: MGI:6183817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191345
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Smad7
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6183817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191345
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Smad7
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6183817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191345
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Smad7
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6183817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191345
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Smad7
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6183817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191345
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Smad7
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6183817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191345
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Smad7
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6183817
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191345
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Smad7
Detected: true
Specimen Num: 6
Publication
First Author: Monteleone I
Year: 2016
Journal: J Crohns Colitis
Title: Smad7 Knockdown Restores Aryl Hydrocarbon Receptor-mediated Protective Signals in the Gut.
Volume: 10
Issue: 6
Pages: 670-7
Publication
First Author: Kugler M
Year: 2017
Journal: Histochem Cell Biol
Title: SMAD7 deficiency stimulates Müller progenitor cell proliferation during the development of the mammalian retina.
Volume: 148
Issue: 1
Pages: 21-32
Publication
First Author: Haupeltshofer S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Smad7 in intestinal CD4+ T cells determines autoimmunity in a spontaneous model of multiple sclerosis.
Volume: 116
Issue: 51
Pages: 25860-25869
Publication  
First Author: Yuan F
Year: 2020
Journal: Mol Metab
Title: Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling.
Volume: 42
Pages: 101084
Publication
First Author: Li R
Year: 2006
Journal: J Immunol
Title: Deletion of exon I of SMAD7 in mice results in altered B cell responses.
Volume: 176
Issue: 11
Pages: 6777-84
Publication  
First Author: Li N
Year: 2014
Journal: Bone
Title: Partial loss of Smad7 function impairs bone remodeling, osteogenesis and enhances osteoclastogenesis in mice.
Volume: 67
Pages: 46-55
Publication
First Author: Liu GX
Year: 2013
Journal: PLoS One
Title: Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NF.κB-dependent mechanisms in mice.
Volume: 8
Issue: 1
Pages: e53573
Publication
First Author: Zhao C
Year: 2017
Journal: Genes Dis
Title: Sox9 augments BMP2-induced chondrogenic differentiation by downregulating Smad7 in mesenchymal stem cells (MSCs).
Volume: 4
Issue: 4
Pages: 229-239
Publication
First Author: Saika S
Year: 2005
Journal: Am J Pathol
Title: Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali.
Volume: 166
Issue: 5
Pages: 1405-18
Publication
First Author: Liu X
Year: 2007
Journal: Biochim Biophys Acta
Title: A 4.3 kb Smad7 promoter is able to specify gene expression during mouse development.
Volume: 1769
Issue: 2
Pages: 149-52
Publication
First Author: Chen Q
Year: 2009
Journal: J Biol Chem
Title: Smad7 is required for the development and function of the heart.
Volume: 284
Issue: 1
Pages: 292-300
Publication
First Author: Zhu L
Year: 2011
Journal: PLoS One
Title: Hepatic deletion of Smad7 in mouse leads to spontaneous liver dysfunction and aggravates alcoholic liver injury.
Volume: 6
Issue: 2
Pages: e17415
Publication
First Author: Kleiter I
Year: 2010
Journal: Brain
Title: Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis.
Volume: 133
Issue: Pt 4
Pages: 1067-81
Publication
First Author: Xiao X
Year: 2017
Journal: J Biol Chem
Title: Forkhead Box Protein 1 (FoxO1) Inhibits Accelerated β Cell Aging in Pancreas-specific SMAD7 Mutant Mice.
Volume: 292
Issue: 8
Pages: 3456-3465
Publication
First Author: Sehrawat A
Year: 2020
Journal: J Biol Chem
Title: SMAD7 enhances adult β-cell proliferation without significantly affecting β-cell function in mice.
Volume: 295
Issue: 15
Pages: 4858-4869
Publication
First Author: Ito Y
Year: 2001
Journal: J Biol Chem
Title: Antagonistic effects of Smad2 versus Smad7 are sensitive to their expression level during tooth development.
Volume: 276
Issue: 47
Pages: 44163-72
Publication
First Author: Denissova NG
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Transforming growth factor beta -inducible independent binding of SMAD to the Smad7 promoter.
Volume: 97
Issue: 12
Pages: 6397-402
Publication
First Author: Vujić Spasić M
Year: 2013
Journal: Biochim Biophys Acta
Title: Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload.
Volume: 1832
Issue: 1
Pages: 76-84
Publication
First Author: Luukko K
Year: 2001
Journal: Mech Dev
Title: Developmentally regulated expression of Smad3, Smad4, Smad6, and Smad7 involved in TGF-beta signaling.
Volume: 101
Issue: 1-2
Pages: 209-12
Publication
First Author: Zwijsen A
Year: 2000
Journal: Dev Dyn
Title: Expression of the inhibitory Smad7 in early mouse development and upregulation during embryonic vasculogenesis.
Volume: 218
Issue: 4
Pages: 663-70
Publication
First Author: Kume S
Year: 2007
Journal: J Biol Chem
Title: SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation.
Volume: 282
Issue: 1
Pages: 151-8
Publication  
First Author: Stolfi C
Year: 2014
Journal: Cell Death Dis
Title: A functional role for Smad7 in sustaining colon cancer cell growth and survival.
Volume: 5
Pages: e1073
Publication
First Author: Ha Thi HT
Year: 2015
Journal: Mol Cell Biol
Title: Smad7 Modulates Epidermal Growth Factor Receptor Turnover through Sequestration of c-Cbl.
Volume: 35
Issue: 16
Pages: 2841-50
Publication
First Author: Krampert M
Year: 2010
Journal: Mol Cell Biol
Title: Smad7 regulates the adult neural stem/progenitor cell pool in a transforming growth factor beta- and bone morphogenetic protein-independent manner.
Volume: 30
Issue: 14
Pages: 3685-94
Publication
First Author: Wei LH
Year: 2013
Journal: PLoS One
Title: Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension.
Volume: 8
Issue: 7
Pages: e70195
Publication
First Author: Li F
Year: 2019
Journal: J Invest Dermatol
Title: Smad7 Ameliorates TGF-β-Mediated Skin Inflammation and Associated Wound Healing Defects but Not Susceptibility to Experimental Skin Carcinogenesis.
Volume: 139
Issue: 4
Pages: 940-950
Publication
First Author: Kuang C
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: In vivo disruption of TGF-beta signaling by Smad7 leads to premalignant ductal lesions in the pancreas.
Volume: 103
Issue: 6
Pages: 1858-63
Publication
First Author: Iwai T
Year: 2008
Journal: J Biol Chem
Title: Smad7 Inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways.
Volume: 283
Issue: 40
Pages: 27154-64
Publication
First Author: Liu W
Year: 2006
Journal: EMBO J
Title: Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.
Volume: 25
Issue: 8
Pages: 1646-58
Publication
First Author: Papangeli I
Year: 2013
Journal: Circ Res
Title: Tbx1 genetically interacts with the transforming growth factor-β/bone morphogenetic protein inhibitor Smad7 during great vessel remodeling.
Volume: 112
Issue: 1
Pages: 90-102
Publication
First Author: Smart NG
Year: 2006
Journal: PLoS Biol
Title: Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus.
Volume: 4
Issue: 2
Pages: e39
Publication
First Author: Tang Y
Year: 2019
Journal: Gastroenterology
Title: Alternative Splice Forms of CYLD Mediate Ubiquitination of SMAD7 to Prevent TGFB Signaling and Promote Colitis.
Volume: 156
Issue: 3
Pages: 692-707.e7
Publication
First Author: Schwalm S
Year: 2017
Journal: Am J Pathol
Title: Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction.
Volume: 187
Issue: 11
Pages: 2413-2429
Publication
First Author: Shukla A
Year: 2016
Journal: PLoS One
Title: Elevating CLIC4 in Multiple Cell Types Reveals a TGF- Dependent Induction of a Dominant Negative Smad7 Splice Variant.
Volume: 11
Issue: 8
Pages: e0161410
Publication
First Author: Meng XM
Year: 2012
Journal: Kidney Int
Title: Disruption of Smad4 impairs TGF-β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro.
Volume: 81
Issue: 3
Pages: 266-79
Publication
First Author: Ha Thi HT
Year: 2019
Journal: Carcinogenesis
Title: SMAD7 in keratinocytes promotes skin carcinogenesis by activating ATM-dependent DNA repair and an EGFR-mediated cell proliferation pathway.
Volume: 40
Issue: 1
Pages: 112-120
Publication  
First Author: Unrau L
Year: 2021
Journal: Int J Mol Sci
Title: Smad7 Deficiency in Myeloid Cells Does Not Affect Liver Injury, Inflammation or Fibrosis after Chronic CCl4 Exposure in Mice.
Volume: 22
Issue: 21
Publication
First Author: Dattaroy D
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis.
Volume: 308
Issue: 4
Pages: G298-312
Publication
First Author: Nakao A
Year: 2000
Journal: J Exp Med
Title: Blockade of transforming growth factor beta/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity.
Volume: 192
Issue: 2
Pages: 151-8
Publication
First Author: Zhao Y
Year: 2011
Journal: J Biol Chem
Title: The deubiquitinase CYLD targets Smad7 protein to regulate transforming growth factor β (TGF-β) signaling and the development of regulatory T cells.
Volume: 286
Issue: 47
Pages: 40520-30
Publication
First Author: Emori T
Year: 2012
Journal: Biol Open
Title: Nuclear Smad7 Overexpressed in Mesenchymal Cells Acts as a Transcriptional Corepressor by Interacting with HDAC-1 and E2F to Regulate Cell Cycle.
Volume: 1
Issue: 3
Pages: 247-60
Publication
First Author: Ka SM
Year: 2012
Journal: Diabetologia
Title: Kidney-targeting Smad7 gene transfer inhibits renal TGF-β/MAD homologue (SMAD) and nuclear factor κB (NF-κB) signalling pathways, and improves diabetic nephropathy in mice.
Volume: 55
Issue: 2
Pages: 509-19
Publication
First Author: Hang L
Year: 2019
Journal: J Immunol
Title: Heligmosomoides polygyrus bakeri Infection Decreases Smad7 Expression in Intestinal CD4+ T Cells, Which Allows TGF-β to Induce IL-10-Producing Regulatory T Cells That Block Colitis.
Volume: 202
Issue: 8
Pages: 2473-2481
Publication
First Author: Lai D
Year: 2018
Journal: Blood
Title: Hepatic Smad7 overexpression causes severe iron overload in mice.
Volume: 131
Issue: 5
Pages: 581-585
Gene
Type: gene
Organism: chicken
Publication
First Author: Snider P
Year: 2009
Journal: Genesis
Title: Generation of Smad7(-Cre) recombinase mice: A useful tool for the study of epithelial-mesenchymal transformation within the embryonic heart.
Volume: 47
Issue: 7
Pages: 469-75
Publication
First Author: Nakao A
Year: 1997
Journal: Nature
Title: Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling.
Volume: 389
Issue: 6651
Pages: 631-5
Publication
First Author: Li X
Year: 2016
Journal: Biochim Biophys Acta
Title: Cerulein-induced pancreatic fibrosis is modulated by Smad7, the major negative regulator of transforming growth factor-β signaling.
Volume: 1862
Issue: 9
Pages: 1839-46
Publication
First Author: Nishimura Y
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Inhibitory Smad proteins promote the differentiation of mouse embryonic stem cells into ependymal-like ciliated cells.
Volume: 401
Issue: 1
Pages: 1-6
Publication
First Author: Tojo M
Year: 2012
Journal: J Biochem
Title: Smad7-deficient mice show growth retardation with reduced viability.
Volume: 151
Issue: 6
Pages: 621-31
Publication
First Author: Wang W
Year: 2005
Journal: J Am Soc Nephrol
Title: Signaling mechanism of TGF-beta1 in prevention of renal inflammation: role of Smad7.
Volume: 16
Issue: 5
Pages: 1371-83
Publication
First Author: Stopa M
Year: 2000
Journal: J Biol Chem
Title: Participation of Smad2, Smad3, and Smad4 in transforming growth factor beta (TGF-beta)-induced activation of Smad7. THE TGF-beta response element of the promoter requires functional Smad binding element and E-box sequences for transcriptional regulation.
Volume: 275
Issue: 38
Pages: 29308-17
Publication
First Author: Kleiter I
Year: 2007
Journal: J Neuroimmunol
Title: Inhibition of Smad7, a negative regulator of TGF-beta signaling, suppresses autoimmune encephalomyelitis.
Volume: 187
Issue: 1-2
Pages: 61-73
Publication
First Author: He J
Year: 2009
Journal: Biochim Biophys Acta
Title: Protection of cerulein-induced pancreatic fibrosis by pancreas-specific expression of Smad7.
Volume: 1792
Issue: 1
Pages: 56-60
Publication
First Author: Li X
Year: 2018
Journal: Exp Cell Res
Title: MicroRNA-21 promotes wound healing via the Smad7-Smad2/3-Elastin pathway.
Volume: 362
Issue: 2
Pages: 245-251
Publication
First Author: Xiao X
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7.
Volume: 111
Issue: 13
Pages: E1211-20