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Search results 1 to 100 out of 370 for Smarca2

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0.039s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: BRM (also know as SMARCA2, BAF190B, SNF2A or SNF2L2) contains the Snf2 family ATPase domain and is a core enzymatic subunit of the SWI/SNF complex, an ATP-dependent chromatin remodelling complex that regulates gene expression through regulating nucleosome remodelling []. In humans SMARCA2 shares 73%sequence identity with BRG1 and has similar ATPase function in the SWI/SNF complex []. Similar to BRG1, SMARCA2 contains a C-terminal bromodomain that may anchor the entire SWI/SNF complex to promoter nucleosomes []. SMARCA2 may function as tumour suppressor []. Heterozygous variants in SMARCA2 gene cause Nicolaides-Baraitser syndrome, which is characterised by sparse hair, distinctive facial morphology, distal-limb anomalies and intellectual disability []. The ATP-dependent helicase brm from Drosophila, which is the ATPase subunit of the Brahma complex for remodeling chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA [], is also included in this entry.
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein
Organism: Mus musculus
Length: 119  
Fragment?: false
Protein
Organism: Mus musculus
Length: 495  
Fragment?: true
Protein
Organism: Mus musculus
Length: 985  
Fragment?: true
Publication
First Author: Van Houdt JK
Year: 2012
Journal: Nat Genet
Title: Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome.
Volume: 44
Issue: 4
Pages: 445-9, S1
Protein
Organism: Mus musculus
Length: 78  
Fragment?: true
Protein
Organism: Mus musculus
Length: 93  
Fragment?: true
Protein
Organism: Mus musculus
Length: 68  
Fragment?: true
Publication
First Author: Tamkun JW
Year: 1992
Journal: Cell
Title: brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2.
Volume: 68
Issue: 3
Pages: 561-72
Publication
First Author: Reisman D
Year: 2009
Journal: Oncogene
Title: The SWI/SNF complex and cancer.
Volume: 28
Issue: 14
Pages: 1653-68
Protein
Organism: Mus musculus
Length: 279  
Fragment?: true
Protein
Organism: Mus musculus
Length: 173  
Fragment?: true
Publication
First Author: Wilson BG
Year: 2014
Journal: Mol Cell Biol
Title: Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation.
Volume: 34
Issue: 6
Pages: 1136-44
Protein
Organism: Mus musculus
Length: 299  
Fragment?: true
Publication
First Author: Shen W
Year: 2007
Journal: Biochemistry
Title: Solution structure of human Brg1 bromodomain and its specific binding to acetylated histone tails.
Volume: 46
Issue: 8
Pages: 2100-10
Protein
Organism: Mus musculus
Length: 1577  
Fragment?: false
Protein
Organism: Mus musculus
Length: 570  
Fragment?: true
Protein
Organism: Mus musculus
Length: 276  
Fragment?: false
Protein
Organism: Mus musculus
Length: 236  
Fragment?: false
Protein
Organism: Mus musculus
Length: 244  
Fragment?: true
Protein
Organism: Mus musculus
Length: 201  
Fragment?: true
Protein
Organism: Mus musculus
Length: 229  
Fragment?: true
Protein
Organism: Mus musculus
Length: 170  
Fragment?: true
Protein
Organism: Mus musculus
Length: 228  
Fragment?: true
Protein
Organism: Mus musculus
Length: 278  
Fragment?: false
Protein
Organism: Mus musculus
Length: 260  
Fragment?: false
Protein
Organism: Mus musculus
Length: 254  
Fragment?: false
Protein
Organism: Mus musculus
Length: 296  
Fragment?: true
Protein
Organism: Mus musculus
Length: 211  
Fragment?: true
Protein
Organism: Mus musculus
Length: 200  
Fragment?: true
Protein
Organism: Mus musculus
Length: 169  
Fragment?: true
Protein
Organism: Mus musculus
Length: 149  
Fragment?: true
Protein
Organism: Mus musculus
Length: 267  
Fragment?: true
Protein
Organism: Mus musculus
Length: 228  
Fragment?: true
Protein
Organism: Mus musculus
Length: 517  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1510  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1510  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1525  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1583  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1601  
Fragment?: false
Publication
First Author: Koga M
Year: 2009
Journal: Hum Mol Genet
Title: Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia.
Volume: 18
Issue: 13
Pages: 2483-94
Publication
First Author: Harikrishnan KN
Year: 2010
Journal: J Neurosci
Title: Alleviating transcriptional inhibition of the norepinephrine slc6a2 transporter gene in depolarized neurons.
Volume: 30
Issue: 4
Pages: 1494-501
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Shen H
Year: 2008
Journal: Cancer Res
Title: The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer.
Volume: 68
Issue: 24
Pages: 10154-62
Publication
First Author: Nguyen KH
Year: 2015
Journal: Stem Cells
Title: SWI/SNF-Mediated Lineage Determination in Mesenchymal Stem Cells Confers Resistance to Osteoporosis.
Volume: 33
Issue: 10
Pages: 3028-38
Publication
First Author: Kahali B
Year: 2014
Journal: Carcinogenesis
Title: Flavonoids from each of the six structural groups reactivate BRM, a possible cofactor for the anticancer effects of flavonoids.
Volume: 35
Issue: 10
Pages: 2183-93
Publication  
First Author: Mehrotra A
Year: 2014
Journal: Arch Biochem Biophys
Title: Modulation of Brahma expression by the mitogen-activated protein kinase/extracellular signal regulated kinase pathway is associated with changes in melanoma proliferation.
Volume: 563
Pages: 125-35
GXD Expression      
Probe: MGI:3816089
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816893
Age: embryonic day 1.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5762701
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5762712
Age: embryonic day 18.5
Image: S9
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5762701
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5762712
Age: embryonic day 15.5
Image: S9
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5762701
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:5762712
Age: embryonic day 12.5
Image: S9
Specimen Num: 7
GXD Expression    
Probe: MGI:5762700
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5762711
Age: embryonic day 18.5
Image: S9
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5762700
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5762711
Age: embryonic day 15.5
Image: S9
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5762700
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:5762711
Age: embryonic day 12.5
Image: S9
Specimen Num: 4
GXD Expression    
Probe: MGI:5762692
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5762710
Age: embryonic day 18.5
Image: S9
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5762692
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5762710
Age: embryonic day 15.5
Image: S9
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5762692
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:5762710
Age: embryonic day 12.5
Image: S9
Specimen Num: 1
GXD Expression    
Probe: MGI:5762591
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5762684
Age: embryonic day 18.5
Image: 4
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5762591
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5762684
Age: embryonic day 15.5
Image: 4
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5762591
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:5762684
Age: embryonic day 12.5
Image: 4
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5762591
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5762684
Age: embryonic day 18.5
Image: 4
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5762591
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5762684
Age: embryonic day 15.5
Image: 4
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5762591
Assay Type: RT-PCR
Annotation Date: 2016-04-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:5762684
Age: embryonic day 12.5
Image: 4
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5762588
Assay Type: Western blot
Annotation Date: 2016-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5762614
Age: embryonic day 18.5
Image: 4
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5762588
Assay Type: Western blot
Annotation Date: 2016-04-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5762614
Age: embryonic day 15.5
Image: 4
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5762588
Assay Type: Western blot
Annotation Date: 2016-04-19
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:5762614
Age: embryonic day 12.5
Image: 4
Specimen Num: 1
GXD Expression    
Probe: MGI:3801437
Assay Type: RT-PCR
Annotation Date: 2008-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3801463
Age: embryonic day 12.5
Image: 5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2661951
Assay Type: Western blot
Annotation Date: 2003-06-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:2661971
Age: embryonic day 18.0
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2661951
Assay Type: Western blot
Annotation Date: 2003-06-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2661971
Age: embryonic day 15.0
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2661951
Assay Type: Western blot
Annotation Date: 2003-06-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:2661971
Age: embryonic day 12.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2661951
Assay Type: Western blot
Annotation Date: 2003-06-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603914
Stage: TS14
Assay Id: MGI:2661971
Age: embryonic day 9.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2661951
Assay Type: Western blot
Annotation Date: 2003-06-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:2661971
Age: embryonic day 7.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3816089
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816893
Age: embryonic day 2.5
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3816089
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816893
Age: embryonic day 3.0
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2661951
Assay Type: Western blot
Annotation Date: 2003-06-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661979
Age: postnatal adult
Detected: false
Specimen Num: 16
GXD Expression      
Probe: MGI:2661951
Assay Type: Western blot
Annotation Date: 2003-06-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661979
Age: postnatal adult
Detected: false
Specimen Num: 15
GXD Expression      
Probe: MGI:2661951
Assay Type: Western blot
Annotation Date: 2003-06-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661979
Age: postnatal adult
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:2661951
Assay Type: Western blot
Annotation Date: 2003-06-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2661979
Age: postnatal adult
Detected: true
Specimen Num: 13