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Search results 1 to 100 out of 1108 for Smarca4

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
6597 | SMARCA4
Type: gene
Organism: human
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Gene
496545 | smarca4
Type: gene
Organism: frog, western clawed
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Gene
171379 | Smarca4
Type: gene
Organism: rat
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Gene
455720 | SMARCA4
Type: gene
Organism: chimpanzee
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Gene
476710 | SMARCA4
Type: gene
Organism: dog, domestic
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Gene
414274 | SMARCA4
Type: gene
Organism: cattle
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Gene
395932 | SMARCA4
Type: gene
Organism: chicken
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Gene
716067 | SMARCA4
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:88192 | Smarca4
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
107985770 | SMANTIS
Type: gene
Organism: human
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Publication
27941795 | J:259253
First Author: Stanton BZ
Year: 2017
Journal: Nat Genet
Title: Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin.
Volume: 49
Issue: 2
Pages: 282-288
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Publication
24752179 | J:212226
First Author: Attanasio C
Year: 2014
Journal: Genome Res
Title: Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis.
Volume: 24
Issue: 6
Pages: 920-9
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Publication
24421395 | J:222133
First Author: Wilson BG
Year: 2014
Journal: Mol Cell Biol
Title: Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation.
Volume: 34
Issue: 6
Pages: 1136-44
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Publication
34140644 | J:308174
First Author: Kim SY
Year: 2021
Journal: Oncogene
Title: SMARCA4 oncogenic potential via IRAK1 enhancer to activate Gankyrin and AKR1B10 in liver cancer.
Volume: 40
Issue: 28
Pages: 4652-4662
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Publication
38458188 | J:346475
First Author: Deng Q
Year: 2024
Journal: Cancer Cell
Title: SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions.
Volume: 42
Issue: 4
Pages: 605-622.e11
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Publication
28608987 | J:247317
First Author: Errichiello E
Year: 2017
Journal: J Pathol
Title: SMARCA4 inactivating mutations cause concomitant Coffin-Siris syndrome, microphthalmia and small-cell carcinoma of the ovary hypercalcaemic type.
Volume: 243
Issue: 1
Pages: 9-15
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Publication
37919824 | J:342253
First Author: Göbel C
Year: 2023
Journal: Acta Neuropathol Commun
Title: MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice.
Volume: 11
Issue: 1
Pages: 174
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Publication
38383496 | J:349032
 
First Author: Göbel C
Year: 2024
Journal: J Neurosci
Title: SMARCA4 Loss and Mutated β-Catenin Induce Proliferative Lesions in the Murine Embryonic Cerebellum.
Volume: 44
Issue: 15
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Publication
37727504 | J:340740
 
First Author: Xu J
Year: 2023
Journal: Front Cell Dev Biol
Title: Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development.
Volume: 11
Pages: 1233317
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Protein
Q8CGJ5
Organism: Mus musculus/domesticus
Length: 545  
Fragment?: true
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Protein
Q6P8K2
Organism: Mus musculus/domesticus
Length: 590  
Fragment?: true
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Protein
Q7TQL1
Organism: Mus musculus/domesticus
Length: 587  
Fragment?: true
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Protein
Q8R569
Organism: Mus musculus/domesticus
Length: 563  
Fragment?: true
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Protein
Q8R0K1
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: true
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Publication
32019910 | J:304197
First Author: Wang P
Year: 2020
Journal: Cell Death Dis
Title: Oncogene-dependent function of BRG1 in hepatocarcinogenesis.
Volume: 11
Issue: 2
Pages: 91
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Publication
25274825 | J:216595
First Author: Moreno N
Year: 2014
Journal: J Neurosci
Title: Loss of Smarc proteins impairs cerebellar development.
Volume: 34
Issue: 40
Pages: 13486-91
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Publication
29892061 | J:271617
First Author: Lissanu Deribe Y
Year: 2018
Journal: Nat Med
Title: Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer.
Volume: 24
Issue: 7
Pages: 1047-1057
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Publication
36440965 | J:335504
First Author: Abedini A
Year: 2023
Journal: Biol Reprod
Title: SWI/SNF chromatin remodeling subunit Smarca4/BRG1 is essential for female fertility†.
Volume: 108
Issue: 2
Pages: 279-291
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Publication
28202515 | J:242086
First Author: Walter DM
Year: 2017
Journal: Cancer Res
Title: Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma.
Volume: 77
Issue: 7
Pages: 1719-1729
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Publication
28431046 | J:241206
First Author: Marathe HG
Year: 2017
Journal: Nucleic Acids Res
Title: BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation.
Volume: 45
Issue: 11
Pages: 6442-6458
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Publication
26163108 | J:239191
First Author: Córdova-Fletes C
Year: 2015
Journal: Neurogenetics
Title: A de novo t(10;19)(q22.3;q13.33) leads to ZMIZ1/PRR12 reciprocal fusion transcripts in a girl with intellectual disability and neuropsychiatric alterations.
Volume: 16
Issue: 4
Pages: 287-98
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Publication
33712604 | J:303562
First Author: Park YK
Year: 2021
Journal: Nat Commun
Title: Interplay of BAF and MLL4 promotes cell type-specific enhancer activation.
Volume: 12
Issue: 1
Pages: 1630
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Publication
29768498 | J:267654
First Author: Saul MC
Year: 2018
Journal: PLoS One
Title: Genomic variants in an inbred mouse model predict mania-like behaviors.
Volume: 13
Issue: 5
Pages: e0197624
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Allele
Smarca4<em1Mgre> | MGI:7713214
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; endonuclease-mediated mutation 1, Michael R Green
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready
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Publication
21118511 | J:168483
First Author: He S
Year: 2010
Journal: Epigenetics Chromatin
Title: Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation.
Volume: 3
Issue: 1
Pages: 21
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Protein Coding Gene
MGP_CAROLIEiJ_G0031879 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034459 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034437 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034428 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034140 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_88192 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034949 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033463 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034272 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034215 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034357 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034258 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034969 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033168 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033578 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014745 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033003 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1825133 | J:19595
First Author: Wassarman DA
Year: 1991
Journal: Nature
Title: RNA splicing. Alive with DEAD proteins.
Volume: 349
Issue: 6309
Pages: 463-4
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Publication
1346755 | J:19594
First Author: Tamkun JW
Year: 1992
Journal: Cell
Title: brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2.
Volume: 68
Issue: 3
Pages: 561-72
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Publication
22363625 | J:185316
First Author: Serber DW
Year: 2012
Journal: PLoS One
Title: The BRG1 chromatin remodeler protects against ovarian cysts, uterine tumors, and mammary tumors in a lineage-specific manner.
Volume: 7
Issue: 2
Pages: e31346
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Publication
16818606 | J:110234
First Author: Bultman SJ
Year: 2006
Journal: Genes Dev
Title: Maternal BRG1 regulates zygotic genome activation in the mouse.
Volume: 20
Issue: 13
Pages: 1744-54
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Publication
14676303 | J:87219
First Author: Gebuhr TC
Year: 2003
Journal: J Exp Med
Title: The role of Brg1, a catalytic subunit of mammalian chromatin-remodeling complexes, in T cell development.
Volume: 198
Issue: 12
Pages: 1937-49
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Publication
29890136 | J:271241
First Author: Kong M
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Hepatocyte-specific deletion of Brg1 alleviates methionine-and-choline-deficient diet (MCD) induced non-alcoholic steatohepatitis in mice.
Volume: 503
Issue: 1
Pages: 344-351
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Publication
38033027 | J:343588
First Author: Wang B
Year: 2023
Journal: PLoS One
Title: Hepatocellular Brg1 promotes CCl4-induced liver inflammation, ECM accumulation and fibrosis in mice.
Volume: 18
Issue: 11
Pages: e0294257
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Publication
30787318 | J:275251
First Author: Wang B
Year: 2019
Journal: Sci Rep
Title: Brg1 promotes liver regeneration after partial hepatectomy via regulation of cell cycle.
Volume: 9
Issue: 1
Pages: 2320
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Publication
12932351 | J:85191
First Author: Chi TH
Year: 2003
Journal: Immunity
Title: Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development.
Volume: 19
Issue: 2
Pages: 169-82
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Publication
19171905 | J:146297
First Author: Kim SI
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: BRG1 requirement for long-range interaction of a locus control region with a downstream promoter.
Volume: 106
Issue: 7
Pages: 2259-64
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Publication
19696073 | J:173020
First Author: Kim SI
Year: 2009
Journal: Nucleic Acids Res
Title: BRG1 directly regulates nucleosome structure and chromatin looping of the alpha globin locus to activate transcription.
Volume: 37
Issue: 18
Pages: 6019-27
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Publication
18483251 | J:135031
First Author: Glaros S
Year: 2008
Journal: Cancer Res
Title: Targeted knockout of BRG1 potentiates lung cancer development.
Volume: 68
Issue: 10
Pages: 3689-96
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Publication
32575410 | J:302368
 
First Author: Wang S
Year: 2020
Journal: Int J Mol Sci
Title: BRG1 Is Dispensable for Sertoli Cell Development and Functions in Mice.
Volume: 21
Issue: 12
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Publication
23339192 | J:196893
First Author: Chen M
Year: 2013
Journal: J Biol Chem
Title: Regulation of microRNAs by Brahma-related gene 1 (Brg1) in smooth muscle cells.
Volume: 288
Issue: 9
Pages: 6397-408
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Publication
23922304 | J:204013
First Author: Holik AZ
Year: 2013
Journal: Stem Cells
Title: Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner.
Volume: 31
Issue: 11
Pages: 2457-66
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Publication
9315656 | J:42997
First Author: Sumi-Ichinose C
Year: 1997
Journal: Mol Cell Biol
Title: SNF2beta-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells.
Volume: 17
Issue: 10
Pages: 5976-86
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Publication
33718362 | J:314058
 
First Author: Kong M
Year: 2021
Journal: Front Cell Dev Biol
Title: The Chromatin Remodeling Protein BRG1 Regulates SREBP Maturation by Activating SCAP Transcription in Hepatocytes.
Volume: 9
Pages: 622866
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Publication
20421421 | J:162669
First Author: Mallappa C
Year: 2010
Journal: Mol Cell Biol
Title: Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function.
Volume: 30
Issue: 13
Pages: 3176-86
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Publication
34260936 | J:321420
First Author: Kim B
Year: 2021
Journal: Cell Rep
Title: Neuronal activity-induced BRG1 phosphorylation regulates enhancer activation.
Volume: 36
Issue: 2
Pages: 109357
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Publication
33816466 | J:314062
 
First Author: Dong W
Year: 2021
Journal: Front Cell Dev Biol
Title: BRG1 Links TLR4 Trans-Activation to LPS-Induced SREBP1a Expression and Liver Injury.
Volume: 9
Pages: 617073
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Publication
34539636 | J:311099
 
First Author: Schmiedel D
Year: 2021
Journal: Front Immunol
Title: Brg1 Supports B Cell Proliferation and Germinal Center Formation Through Enhancer Activation.
Volume: 12
Pages: 705848
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Publication
31228616 | J:283494
First Author: Liu L
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: BRG1 regulates endothelial-derived IL-33 to promote ischemia-reperfusion induced renal injury and fibrosis in mice.
Volume: 1865
Issue: 9
Pages: 2551-2561
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Publication
30293567 | J:270738
First Author: Li Z
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: BRG1 regulates NOX gene transcription in endothelial cells and contributes to cardiac ischemia-reperfusion injury.
Volume: 1864
Issue: 10
Pages: 3477-3486
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Publication
30293568 | J:270554
First Author: Li N
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: The chromatin remodeling protein BRG1 regulates APAP-induced liver injury by modulating CYP3A11 transcription in hepatocyte.
Volume: 1864
Issue: 10
Pages: 3487-3495
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Publication
31750301 | J:290071
 
First Author: Li Z
Year: 2019
Journal: Front Cell Dev Biol
Title: The Chromatin Remodeler Brg1 Integrates ROS Production and Endothelial-Mesenchymal Transition to Promote Liver Fibrosis in Mice.
Volume: 7
Pages: 245
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Publication
22318225 | J:182753
First Author: Kim Y
Year: 2012
Journal: Development
Title: An essential role for a mammalian SWI/SNF chromatin-remodeling complex during male meiosis.
Volume: 139
Issue: 6
Pages: 1133-40
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Publication
32478075 | J:291931
 
First Author: Dong W
Year: 2020
Journal: Front Cell Dev Biol
Title: Activation of TWIST Transcription by Chromatin Remodeling Protein BRG1 Contributes to Liver Fibrosis in Mice.
Volume: 8
Pages: 340
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Publication
31349970 | J:291670
First Author: Liu L
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Endothelial-specific deletion of Brahma-related gene 1 (BRG1) assuages unilateral ureteral obstruction induced renal injury in mice.
Volume: 517
Issue: 2
Pages: 244-252
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Publication
32500071 | J:291068
 
First Author: Fan Z
Year: 2020
Journal: Front Cell Dev Biol
Title: Brahma Related Gene 1 (Brg1) Regulates Cellular Cholesterol Synthesis by Acting as a Co-factor for SREBP2.
Volume: 8
Pages: 259
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Publication
23392668 | J:194276
First Author: Limpert AS
Year: 2013
Journal: J Neurosci
Title: NF-κB forms a complex with the chromatin remodeler BRG1 to regulate Schwann cell differentiation.
Volume: 33
Issue: 6
Pages: 2388-97
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Publication
22495890 | J:185819
First Author: Wang J
Year: 2012
Journal: Biol Reprod
Title: Essential roles of the chromatin remodeling factor BRG1 in spermatogenesis in mice.
Volume: 86
Issue: 6
Pages: 186
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Publication
25929186 | J:233470
 
First Author: Cao M
Year: 2015
Journal: Neurosci Lett
Title: Camk2a-Cre-mediated conditional deletion of chromatin remodeler Brg1 causes perinatal hydrocephalus.
Volume: 597
Pages: 71-6
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Publication
24172864 | J:220654
First Author: Chandler RL
Year: 2014
Journal: Epigenetics
Title: Characterization of a Brg1 hypomorphic allele demonstrates that genetic and biochemical activity are tightly correlated.
Volume: 9
Issue: 2
Pages: 249-56
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Publication
30336142 | J:266634
 
First Author: Zhang X
Year: 2018
Journal: J Mol Cell Cardiol
Title: Brg1 trans-activates endothelium-derived colony stimulating factor to promote calcium chloride induced abdominal aortic aneurysm in mice.
Volume: 125
Pages: 6-17
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Publication
16800816 | J:116030
First Author: Xu Z
Year: 2006
Journal: Biochem J
Title: Recruitment of the SWI/SNF protein Brg1 by a multiprotein complex effects transcriptional repression in murine erythroid progenitors.
Volume: 399
Issue: 2
Pages: 297-304
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Publication
18852284 | J:143289
First Author: Wurster AL
Year: 2008
Journal: Mol Cell Biol
Title: BRG1-mediated chromatin remodeling regulates differentiation and gene expression of T helper cells.
Volume: 28
Issue: 24
Pages: 7274-85
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Publication
18344520 | J:173074
First Author: Brettingham-Moore KH
Year: 2008
Journal: Nucleic Acids Res
Title: Determinants of a transcriptionally competent environment at the GM-CSF promoter.
Volume: 36
Issue: 8
Pages: 2639-53
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Publication
25010414 | J:228537
First Author: Holik AZ
Year: 2014
Journal: PLoS Genet
Title: Brg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestine.
Volume: 10
Issue: 7
Pages: e1004453
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Publication
30149919 | J:270922
First Author: Zou W
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Brg1 aggravates airway inflammation in asthma via inhibition of the PI3K/Akt/mTOR pathway.
Volume: 503
Issue: 4
Pages: 3212-3218
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Publication
30001167 | J:286709
First Author: Li N
Year: 2019
Journal: FASEB J
Title: Brahma related gene 1 (Brg1) contributes to liver regeneration by epigenetically activating the Wnt/β-catenin pathway in mice.
Volume: 33
Issue: 1
Pages: 327-338
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Publication
28798861 | J:278610
 
First Author: Ge M
Year: 2017
Journal: Oxid Med Cell Longev
Title: Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects.
Volume: 2017
Pages: 8787392
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Publication
31635808 | J:291362
First Author: Shao J
Year: 2020
Journal: Biochem Biophys Res Commun
Title: BRG1 deficiency in endothelial cells alleviates thioacetamide induced liver fibrosis in mice.
Volume: 521
Issue: 1
Pages: 212-219
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Publication
25792600 | J:320723
First Author: Roy N
Year: 2015
Journal: Genes Dev
Title: Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation.
Volume: 29
Issue: 6
Pages: 658-71
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Publication
36427449 | J:334409
 
First Author: Xu M
Year: 2023
Journal: Mol Immunol
Title: Knockdown of Brg1 reduced mucus secretion in HDM stimulated airway inflammation.
Volume: 153
Pages: 42-50
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Publication
36776858 | J:333340
 
First Author: Wang XJ
Year: 2023
Journal: Front Immunol
Title: Suppression of microRNA-222-3p ameliorates ulcerative colitis and colitis-associated colorectal cancer to protect against oxidative stress via targeting BRG1 to activate Nrf2/HO-1 signaling pathway.
Volume: 14
Pages: 1089809
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Publication
38652118 | J:357556
 
First Author: Wang J
Year: 2024
Journal: J Cell Biol
Title: BRG1 programs PRC2-complex repression and controls oligodendrocyte differentiation and remyelination.
Volume: 223
Issue: 7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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