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Search results 1 to 100 out of 100 for Smcr8

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
140775 | SMCR8
Type: gene
Organism: human
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Gene
100486182 | smcr8
Type: gene
Organism: frog, western clawed
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Gene
119881483 | SMCR8
Type: gene
Organism: dog, domestic
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Gene
497918 | Smcr8
Type: gene
Organism: rat
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Gene
743260 | SMCR8
Type: gene
Organism: chimpanzee
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Gene
781661 | SMCR8
Type: gene
Organism: cattle
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Gene
416519 | SMCR8
Type: gene
Organism: chicken
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Gene
701074 | SMCR8
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2444720 | Smcr8
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30696333 | J:294772
First Author: Lan Y
Year: 2019
Journal: Autophagy
Title: SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis.
Volume: 15
Issue: 5
Pages: 871-885
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Publication
29950492 | J:272433
First Author: Zhang Y
Year: 2018
Journal: Genes Dev
Title: The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis.
Volume: 32
Issue: 13-14
Pages: 929-943
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Publication
31625563 | J:290045
First Author: Liang C
Year: 2019
Journal: Hum Mol Genet
Title: Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models.
Volume: 28
Issue: 23
Pages: 3940-3953
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Publication
31847700 | J:302680
First Author: Shao Q
Year: 2020
Journal: Autophagy
Title: C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis.
Volume: 16
Issue: 9
Pages: 1635-1650
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Publication
27875531 | J:237194
First Author: Ugolino J
Year: 2016
Journal: PLoS Genet
Title: Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling.
Volume: 12
Issue: 11
Pages: e1006443
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Publication
27617292 | J:236977
First Author: Yang M
Year: 2016
Journal: Sci Adv
Title: A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy.
Volume: 2
Issue: 9
Pages: e1601167
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Publication
31651360 | J:292854
First Author: Xiao S
Year: 2019
Journal: Acta Neuropathol Commun
Title: Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels.
Volume: 7
Issue: 1
Pages: 161
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Publication
30442666 | J:268243
First Author: McAlpine W
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function.
Volume: 115
Issue: 49
Pages: E11523-E11531
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Protein Coding Gene
MGP_CAROLIEiJ_G0016463 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018425 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018365 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018178 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2444720 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018817 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017735 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018152 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018261 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018252 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018334 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018276 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018858 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017508 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017787 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017593 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017298 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
17273973 | J:125240
First Author: Yan J
Year: 2007
Journal: Am J Hum Genet
Title: Penetrance of craniofacial anomalies in mouse models of Smith-Magenis syndrome is modified by genomic sequence surrounding Rai1: not all null alleles are alike.
Volume: 80
Issue: 3
Pages: 518-25
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Guanine nucleotide exchange protein SMCR8
Type: chain
End: 935
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Publication
27193190 | J:240578
First Author: Sullivan PM
Year: 2016
Journal: Acta Neuropathol Commun
Title: The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway.
Volume: 4
Issue: 1
Pages: 51
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Protein
Q3UMB5
Organism: Mus musculus/domesticus
Length: 935  
Fragment?: false
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Protein
Q3UMB5-2
Organism: Mus musculus/domesticus
Length: 785  
Fragment?: false
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Allele
Smcr8<em1Smoc> | MGI:7292480
Name: Smith-Magenis syndrome chromosome region, candidate 8 homolog (human); endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
28195531 | -
   
First Author: Jung J
Year: 2017
Journal: Elife
Title: Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator.
Volume: 6
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Strain
MGI:6476342 | C57BL/6JSmoc-Smcr8<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
11997338 | J:76499
First Author: Bi W
Year: 2002
Journal: Genome Res
Title: Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse.
Volume: 12
Issue: 5
Pages: 713-28
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Allele
Smcr8<em1Btlr> | MGI:6272384
Name: Smith-Magenis syndrome chromosome region, candidate 8 homolog (human); endonuclease-mediated mutation 1, Bruce Beutler
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Smcr8<em2Btlr> | MGI:6272388
Name: Smith-Magenis syndrome chromosome region, candidate 8 homolog (human); endonuclease-mediated mutation 2, Bruce Beutler
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Smcr8<m2Btlr> | MGI:6272382
Name: Smith-Magenis syndrome chromosome region, candidate 8 homolog (human); mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6272630 | C57BL/6J-Smcr8<m2Btlr>
Attribute String: coisogenic, chemically induced mutation, mutant strain
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Allele
Smcr8<m3Btlr> | MGI:6272383
Name: Smith-Magenis syndrome chromosome region, candidate 8 homolog (human); mutation 3, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6272628 | C57BL/6J-Smcr8<m3Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Strain
MGI:6272626 | C57BL/6J-Smcr8<em1Btlr>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6272624 | C57BL/6J-Smcr8<em2Btlr>
Attribute String: mutant strain, endonuclease-mediated mutation, coisogenic
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Allele
Smcr8<m1Btlr> | MGI:6272372
Name: Smith-Magenis syndrome chromosome region, candidate 8 homolog (human); mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6272632 | C57BL/6J-Smcr8<m1Btlr>
Attribute String: coisogenic, mutant strain, chemically induced mutation
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Genotype
Genotype
Symbol: Smcr8/Smcr8
Background: C57BL/6J-Smcr8
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smcr8/Smcr8
Background: C57BL/6J-Smcr8
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smcr8/Smcr8<+>
Background: C57BL/6J-Smcr8
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smcr8/Smcr8
Background: C57BL/6J-Smcr8
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smcr8/Smcr8
Background: C57BL/6J-Smcr8
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smcr8/Smcr8
Background: C57BL/6J-Smcr8
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Smcr8/Smcr8 Tlr3/Tlr3 Tlr7/Tlr7 Tlr9/Tlr9
Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Publication
27103069 | J:233688
First Author: Sellier C
Year: 2016
Journal: EMBO J
Title: Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.
Volume: 35
Issue: 12
Pages: 1276-97
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Publication
36322143 | J:351876
First Author: Ma L
Year: 2023
Journal: Hum Mol Genet
Title: Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors.
Volume: 32
Issue: 8
Pages: 1252-1265
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Publication
17242355 | -
First Author: Villén J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Large-scale phosphorylation analysis of mouse liver.
Volume: 104
Issue: 5
Pages: 1488-93
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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