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Search results 1 to 81 out of 81 for Snx14

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
57231 | SNX14
Type: gene
Organism: human
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Gene
780262 | snx14
Type: gene
Organism: frog, western clawed
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Gene
315871 | Snx14
Type: gene
Organism: rat
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Gene
474985 | SNX14
Type: gene
Organism: dog, domestic
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Gene
462865 | SNX14
Type: gene
Organism: chimpanzee
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Gene
533801 | SNX14
Type: gene
Organism: cattle
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Gene
421832 | SNX14
Type: gene
Organism: chicken
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Gene
555970 | snx14
Type: gene
Organism: zebrafish
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Gene
696632 | SNX14
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2155664 | Snx14
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
38625743 | J:353340
 
First Author: Zhou Y
Year: 2024
Journal: JCI Insight
Title: Altered lipid homeostasis is associated with cerebellar neurodegeneration in SNX14 deficiency.
Volume: 9
Issue: 10
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Publication
24859318 | J:217344
First Author: Huang HS
Year: 2014
Journal: PLoS One
Title: Snx14 regulates neuronal excitability, promotes synaptic transmission, and is imprinted in the brain of mice.
Volume: 9
Issue: 5
Pages: e98383
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Publication
11500980 | J:70707
First Author: Carroll P
Year: 2001
Journal: Dev Dyn
Title: Sorting nexin-14, a gene expressed in motoneurons trapped by an in vitro preselection method.
Volume: 221
Issue: 4
Pages: 431-42
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Publication
32792680 | J:294712
First Author: Bryant D
Year: 2020
Journal: Sci Rep
Title: Diverse species-specific phenotypic consequences of loss of function sorting nexin 14 mutations.
Volume: 10
Issue: 1
Pages: 13763
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Protein Coding Gene
MGP_CAROLIEiJ_G0032507 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035107 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035088 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035016 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035076 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034788 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2155664 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035600 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034761 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034919 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034862 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035000 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035620 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034223 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015374 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033646 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5640736
Assay Type: RT-PCR
Annotation Date: 2015-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3647224
Stage: TS24
Assay Id: MGI:5640833
Age: embryonic day 16.5
Image: S5
Specimen Label: bv/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5640736
Assay Type: RT-PCR
Annotation Date: 2015-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3647224
Stage: TS24
Assay Id: MGI:5640833
Age: embryonic day 16.5
Image: S5
Specimen Label: bv/bv
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5640736
Assay Type: RT-PCR
Annotation Date: 2015-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5641083
Age: postnatal day 15
Image: S7
Specimen Label: bv/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5640736
Assay Type: RT-PCR
Annotation Date: 2015-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5641083
Age: postnatal day 15
Image: S7
Specimen Label: bv/bv
Detected: true
Specimen Num: 2
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Protein
Q80XP2
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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Publication
23055939 | J:193641
First Author: Nakano Y
Year: 2012
Journal: PLoS Genet
Title: A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.
Volume: 8
Issue: 10
Pages: e1002966
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
25848753 | -
First Author: Akizu N
Year: 2015
Journal: Nat Genet
Title: Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction.
Volume: 47
Issue: 5
Pages: 528-34
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Publication
25795301 | -
First Author: Ha CM
Year: 2015
Journal: J Cell Sci
Title: SNX14 is a bifunctional negative regulator for neuronal 5-HT6 receptor signaling.
Volume: 128
Issue: 9
Pages: 1848-61
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Allele
Snx14<em1Naki> | MGI:7785458
Name: sorting nexin 14; endonuclease-mediated mutation 1, Naiara Akizu
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7788837 | C57BL/6-Snx14<em1Naki>/J
Attribute String: endonuclease-mediated mutation, mutant strain
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DO Term
DOID:0080066 | autosomal recessive spinocerebellar ataxia 20
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Protein Domain
IPR037892 | SNX14_RGS
Type: Domain
Description: This entry represents the RGS domain of SNX14 (Sorting Nexin14). RGS domain is a small α-helical structure that acts as GAPs for Galpha subunits of heterotrimeric G-proteins, and thus plays critical roles in attenuating G-protein coupled receptor (GPCR) signaling []. SNX14 is believed to regulate membrane trafficking in motor neurons []. It has been found localized to lysosomes and associated with phosphatidylinositol (3,5)-bisphosphate, a key component of late endosomes/lysosomes [].
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Publication
25148684 | J:215447
First Author: Mas C
Year: 2014
Journal: J Biol Chem
Title: Structural basis for different phosphoinositide specificities of the PX domains of sorting nexins regulating G-protein signaling.
Volume: 289
Issue: 41
Pages: 28554-68
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Protein Domain
IPR037436 | SNX14_PX
Type: Domain
Description: SNX14 (sorting nexin-14) is expressed in the embryonic nervous system of mammals such as mice, being co-expressed with homoprotein islet-1 in several tissues []. SNX14 levels increase progressively during neuronal development and its knockdown impairs both excitatory and inhibitory synaptic transmission, suggesting a role in neuronal development and function []. SNX14 contains an N-terminal PXA domain, a regulator of G protein signaling (RGS) domain, a PX domain, and a C-terminal PXC domain []. Its RGS domain is non-functional as a GTPase activator for Galpha, but it binds to and sequesters Galpha, thus inhibiting downstream cAMP production [].This entry represents the PX domain of SNX14. The PX domain is a phosphoinositide (PI) binding module present in many proteins with diverse functions [, ].
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Publication
11684018 | -
First Author: Bravo J
Year: 2001
Journal: Mol Cell
Title: The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate.
Volume: 8
Issue: 4
Pages: 829-39
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Protein
Q8BHY8
Organism: Mus musculus/domesticus
Length: 964  
Fragment?: false
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Protein
G3UX33
Organism: Mus musculus/domesticus
Length: 946  
Fragment?: false
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Protein
A0A6Q6RCM4
Organism: Mus musculus/domesticus
Length: 937  
Fragment?: false
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Protein
G3UXB6
Organism: Mus musculus/domesticus
Length: 893  
Fragment?: false
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Protein
Q8BHZ1
Organism: Mus musculus/domesticus
Length: 495  
Fragment?: true
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Publication
16782399 | -
First Author: Seet LF
Year: 2006
Journal: Biochim Biophys Acta
Title: The Phox (PX) domain proteins and membrane traffic.
Volume: 1761
Issue: 8
Pages: 878-96
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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