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Search results 1 to 76 out of 76 for Snx14

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
57231 | SNX14
Type: gene
Organism: human
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Gene
462865 | SNX14
Type: gene
Organism: chimpanzee
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Gene
533801 | SNX14
Type: gene
Organism: cattle
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Gene
421832 | SNX14
Type: gene
Organism: chicken
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Gene
555970 | snx14
Type: gene
Organism: zebrafish
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Gene
696632 | SNX14
Type: gene
Organism: macaque, rhesus
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Gene
780262 | snx14
Type: gene
Organism: frog, western clawed
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Gene
315871 | Snx14
Type: gene
Organism: rat
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Gene
474985 | SNX14
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:2155664 | Snx14
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24859318 | J:217344
First Author: Huang HS
Year: 2014
Journal: PLoS One
Title: Snx14 regulates neuronal excitability, promotes synaptic transmission, and is imprinted in the brain of mice.
Volume: 9
Issue: 5
Pages: e98383
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Publication
11500980 | J:70707
First Author: Carroll P
Year: 2001
Journal: Dev Dyn
Title: Sorting nexin-14, a gene expressed in motoneurons trapped by an in vitro preselection method.
Volume: 221
Issue: 4
Pages: 431-42
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Publication
32792680 | J:294712
First Author: Bryant D
Year: 2020
Journal: Sci Rep
Title: Diverse species-specific phenotypic consequences of loss of function sorting nexin 14 mutations.
Volume: 10
Issue: 1
Pages: 13763
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Protein Coding Gene
MGP_CAROLIEiJ_G0032507 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035107 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035088 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035016 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035076 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034788 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2155664 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035600 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034761 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034919 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034862 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035000 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035620 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034223 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015374 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033646 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5640736
Assay Type: RT-PCR
Annotation Date: 2015-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3647224
Stage: TS24
Assay Id: MGI:5640833
Age: embryonic day 16.5
Image: S5
Specimen Label: bv/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5640736
Assay Type: RT-PCR
Annotation Date: 2015-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3647224
Stage: TS24
Assay Id: MGI:5640833
Age: embryonic day 16.5
Image: S5
Specimen Label: bv/bv
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5640736
Assay Type: RT-PCR
Annotation Date: 2015-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5641083
Age: postnatal day 15
Image: S7
Specimen Label: bv/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5640736
Assay Type: RT-PCR
Annotation Date: 2015-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5641083
Age: postnatal day 15
Image: S7
Specimen Label: bv/bv
Detected: true
Specimen Num: 2
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Publication
23055939 | J:193641
First Author: Nakano Y
Year: 2012
Journal: PLoS Genet
Title: A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.
Volume: 8
Issue: 10
Pages: e1002966
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Protein
Q80XP2
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: false
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
25848753 | -
First Author: Akizu N
Year: 2015
Journal: Nat Genet
Title: Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction.
Volume: 47
Issue: 5
Pages: 528-34
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Publication
25795301 | -
First Author: Ha CM
Year: 2015
Journal: J Cell Sci
Title: SNX14 is a bifunctional negative regulator for neuronal 5-HT6 receptor signaling.
Volume: 128
Issue: 9
Pages: 1848-61
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DO Term
DOID:0080066 | autosomal recessive spinocerebellar ataxia 20
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Protein Domain
IPR037892 | SNX14_RGS
Type: Domain
Description: This entry represents the RGS domain of SNX14 (Sorting Nexin14). RGS domain is a small α-helical structure that acts as GAPs for Galpha subunits of heterotrimeric G-proteins, and thus plays critical roles in attenuating G-protein coupled receptor (GPCR) signaling []. SNX14 is believed to regulate membrane trafficking in motor neurons []. It has been found localized to lysosomes and associated with phosphatidylinositol (3,5)-bisphosphate, a key component of late endosomes/lysosomes [].
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Publication
25148684 | J:215447
First Author: Mas C
Year: 2014
Journal: J Biol Chem
Title: Structural basis for different phosphoinositide specificities of the PX domains of sorting nexins regulating G-protein signaling.
Volume: 289
Issue: 41
Pages: 28554-68
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Protein Domain
IPR037436 | SNX14_PX
Type: Domain
Description: SNX14 (sorting nexin-14) is expressed in the embryonic nervous system of mammals such as mice, being co-expressed with homoprotein islet-1 in several tissues []. SNX14 levels increase progressively during neuronal development and its knockdown impairs both excitatory and inhibitory synaptic transmission, suggesting a role in neuronal development and function []. SNX14 contains an N-terminal PXA domain, a regulator of G protein signaling (RGS) domain, a PX domain, and a C-terminal PXC domain []. Its RGS domain is non-functional as a GTPase activator for Galpha, but it binds to and sequesters Galpha, thus inhibiting downstream cAMP production [].This entry represents the PX domain of SNX14. The PX domain is a phosphoinositide (PI) binding module present in many proteins with diverse functions [, ].
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Publication
11684018 | -
First Author: Bravo J
Year: 2001
Journal: Mol Cell
Title: The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate.
Volume: 8
Issue: 4
Pages: 829-39
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Protein
Q8BHY8
Organism: Mus musculus/domesticus
Length: 964  
Fragment?: false
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Protein
G3UX33
Organism: Mus musculus/domesticus
Length: 946  
Fragment?: false
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Protein
A0A6Q6RCM4
Organism: Mus musculus/domesticus
Length: 937  
Fragment?: false
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Protein
G3UXB6
Organism: Mus musculus/domesticus
Length: 893  
Fragment?: false
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Protein
Q8BHZ1
Organism: Mus musculus/domesticus
Length: 495  
Fragment?: true
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Publication
16782399 | -
First Author: Seet LF
Year: 2006
Journal: Biochim Biophys Acta
Title: The Phox (PX) domain proteins and membrane traffic.
Volume: 1761
Issue: 8
Pages: 878-96
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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