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Search results 1 to 71 out of 71 for Snx19

0.035s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Sorting nexins (SNXs) or phox homology (PX) domain-containing proteins are central regulators of cell trafficking and signalling []. SNX19, like SNX13, SNX14, and SNX25, possesses two unique PX-associated domains, but lacks the G protein-coupled receptor signaling (RGS) domain present in the others []. It plays a critical role in cartilage formation (chondrogenesis) and may be a protective factor against the progression of cartilage degradation in osteoarthritis []. SNX19 is related to several diseases, including thyroid tumors and coronary heart disease [, ].
Publication
First Author: Mas C
Year: 2014
Journal: J Biol Chem
Title: Structural basis for different phosphoinositide specificities of the PX domains of sorting nexins regulating G-protein signaling.
Volume: 289
Issue: 41
Pages: 28554-68
Publication
First Author: Kan A
Year: 2009
Journal: Arthritis Rheum
Title: Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER: identification of sorting nexin 19 as a novel factor.
Volume: 60
Issue: 11
Pages: 3314-23
Protein
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 225  
Fragment?: true
Publication
First Author: Jacques C
Year: 2005
Journal: J Clin Endocrinol Metab
Title: Two-step differential expression analysis reveals a new set of genes involved in thyroid oncocytic tumors.
Volume: 90
Issue: 4
Pages: 2314-20
Publication
First Author: Bare LA
Year: 2007
Journal: Genet Med
Title: Five common gene variants identify elevated genetic risk for coronary heart disease.
Volume: 9
Issue: 10
Pages: 682-9
Publication
First Author: Teasdale RD
Year: 2012
Journal: Biochem J
Title: Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease.
Volume: 441
Issue: 1
Pages: 39-59
Protein
Organism: Mus musculus/domesticus
Length: 997  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 567  
Fragment?: true
Publication
First Author: Harashima S
Year: 2012
Journal: J Diabetes Investig
Title: Sorting nexin 19 regulates the number of dense core vesicles in pancreatic β-cells.
Volume: 3
Issue: 1
Pages: 52-61
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:5615800
Assay Type: RNA in situ
Annotation Date: 2015-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640519
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5615802
Age: embryonic day 11.5
Specimen Label: 4A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5615800
Assay Type: RNA in situ
Annotation Date: 2015-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266919
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5615802
Age: embryonic day 11.5
Specimen Label: 4A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5615804
Assay Type: Immunohistochemistry
Annotation Date: 2015-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914225
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5615807
Age: embryonic day 17.5
Note: Expression is in the limb cartilage of the proximal tibia, especially in proliferative chondrocytes.
Specimen Label: 4B
Detected: true
Specimen Num: 1
Publication
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Protein Domain
Type: Domain
Description: Sorting nexins (SNXs) or phox homology (PX) domain-containing proteins are central regulators of cell trafficking and signalling []. SNX19, like SNX13, SNX14, and SNX25, possesses two unique PX-associated domains, but lacks the G protein-coupled receptor signaling (RGS) domain present in the others []. It plays a critical role in cartilage formation (chondrogenesis) and may be a protective factor againstthe progression of cartilage degradation in osteoarthritis []. SNX19 is related to several diseases, including thyroid tumors and coronary heart disease [, ].This entry represents the PX domain of SNX19.