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Search results 1 to 100 out of 104 for Snx9

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Hits by Strain

Type Details Score
Gene
51429 | SNX9
Type: gene
Organism: human
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Gene
100145698 | snx9
Type: gene
Organism: frog, western clawed
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Gene
476254 | SNX9
Type: gene
Organism: dog, domestic
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Gene
472172 | SNX9
Type: gene
Organism: chimpanzee
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Gene
683687 | Snx9
Type: gene
Organism: rat
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Gene
506218 | SNX9
Type: gene
Organism: cattle
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Gene
421654 | SNX9
Type: gene
Organism: chicken
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Gene
706016 | SNX9
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1913866 | Snx9
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR028644 | SNX9
Type: Family
Description: Sorting nexins are a large family of evolutionarily conserved phosphoinositide-binding proteins that have roles in cargo sorting through the endosomal netwrok []. Sorting nexins contain at least a PX domain (a phospholipid-binding motif). Some nexins contain a few additional domains. Proteins in the sorting nexin 9 subfamily includes SNX9, SNX18 and SNX33 []. They are characterised by the presence of an N-terminal SH3 domain (), a PX domain that is a phosphoinositide-binding module (), and a Bin/Amphiphysin/Rvs (BAR) domain at the C terminus, which allows membrane binding and bending. They are required for progression and completion of mitosis []. Sorting nexin 9 (SNX9) is a well-characterised member of this group; it is has been suggested to be involved in the endocytic process as an accessory factor []. SNX9 has binding sites for both clathrin and adaptor protein AP-2 in a low complexity region, and binds dynamin-2 (Dyn2) by its SH3 domain. SNX9 has its own membrane-binding activity, mediated by a carboxyl-terminal region containing the PX domain and the BAR domain []. Endogenous SNX9 partially co-localizes with AP-2 and Dyn2 at the plasma membrane, and over expression in K562 and HeLa cells of truncated versions of SNX9 inhibits the uptake of transferrin []. Moreover, SNX9 is required for efficient clathrin-mediated endocytosis, which suggests that it functions to regulate dynamin activity [].
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Gene
105378078 | SNX9-AS1
Type: gene
Organism: human
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Publication
15703209 | -
First Author: Soulet F
Year: 2005
Journal: Mol Biol Cell
Title: SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.
Volume: 16
Issue: 4
Pages: 2058-67
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Publication
12952949 | -
First Author: Lundmark R
Year: 2003
Journal: J Biol Chem
Title: Sorting nexin 9 participates in clathrin-mediated endocytosis through interactions with the core components.
Volume: 278
Issue: 47
Pages: 46772-81
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Publication
11879186 | -
First Author: Lundmark R
Year: 2002
Journal: Biochem J
Title: The beta-appendages of the four adaptor-protein (AP) complexes: structure and binding properties, and identification of sorting nexin 9 as an accessory protein to AP-2.
Volume: 362
Issue: Pt 3
Pages: 597-607
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Protein
Q9CZK0
Organism: Mus musculus/domesticus
Length: 410  
Fragment?: true
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Protein
Q91VH2
Organism: Mus musculus/domesticus
Length: 595  
Fragment?: false
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Protein
Q3U1P2
Organism: Mus musculus/domesticus
Length: 595  
Fragment?: false
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Protein
Q3TZU7
Organism: Mus musculus/domesticus
Length: 595  
Fragment?: false
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Publication
22718350 | -
First Author: Ma MP
Year: 2012
Journal: J Cell Sci
Title: SNX9, SNX18 and SNX33 are required for progression through and completion of mitosis.
Volume: 125
Issue: Pt 18
Pages: 4372-82
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Publication
22193161 | -
First Author: Cullen PJ
Year: 2011
Journal: Nat Cell Biol
Title: Sorting nexins provide diversity for retromer-dependent trafficking events.
Volume: 14
Issue: 1
Pages: 29-37
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Publication
27655699 | J:314970
First Author: Liu C
Year: 2016
Journal: Oncotarget
Title: Sorting nexin 9 (SNX9) is not essential for development and auditory function in mice.
Volume: 7
Issue: 42
Pages: 68921-68932
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Publication
34168078 | J:343811
 
First Author: Kawasaki T
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Loss of FCHSD1 leads to amelioration of chronic obstructive pulmonary disease.
Volume: 118
Issue: 26
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Publication
23437151 | J:283192
First Author: Cao H
Year: 2013
Journal: PLoS One
Title: FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro.
Volume: 8
Issue: 2
Pages: e56516
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Publication
12917015 | J:86675
First Author: MaCaulay SL
Year: 2003
Journal: Biochem J
Title: Insulin stimulates movement of sorting nexin 9 between cellular compartments: a putative role mediating cell surface receptor expression and insulin action.
Volume: 376
Issue: Pt 1
Pages: 123-34
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Protein Coding Gene
MGP_CAROLIEiJ_G0021025 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023107 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023077 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023043 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023080 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022840 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1913866 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0023525 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022358 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022807 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022942 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022915 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0023544 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022102 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0022408 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023343 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021930 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:4424036
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1792123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828370
Age: embryonic day 14.5
Image: euxassay_012283_07
Specimen Label: euxassay_012283_07
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4424036
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1792123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828370
Age: embryonic day 14.5
Image: euxassay_012283_19
Specimen Label: euxassay_012283_19
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4424036
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828370
Age: embryonic day 14.5
Image: euxassay_012283_07
Specimen Label: euxassay_012283_07
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4424036
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828370
Age: embryonic day 14.5
Image: euxassay_012283_19
Specimen Label: euxassay_012283_19
Detected: true
Specimen Num: 2
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Publication
- | J:73226
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, similar to sorting nexin 9, clone MGC:6327 IMAGE:3257422, mRNA, complete cds
Pages: BC014814
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Publication
25107275 | J:248446
 
First Author: Nández R
Year: 2014
Journal: Elife
Title: A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells.
Volume: 3
Pages: e02975
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Publication
15722415 | J:97017
First Author: Schimenti JC
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Mutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortion.
Volume: 102
Issue: 9
Pages: 3342-7
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Publication
39043703 | J:352092
First Author: Wang L
Year: 2024
Journal: Nat Commun
Title: Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition.
Volume: 15
Issue: 1
Pages: 6209
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
36732507 | J:351835
First Author: Trefny MP
Year: 2023
Journal: Nat Commun
Title: Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.
Volume: 14
Issue: 1
Pages: 86
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Allele
Snx9<em2Smoc> | MGI:7292512
Name: sorting nexin 9; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
20427313 | -
First Author: Park J
Year: 2010
Journal: J Cell Sci
Title: SNX18 shares a redundant role with SNX9 and modulates endocytic trafficking at the plasma membrane.
Volume: 123
Issue: Pt 10
Pages: 1742-50
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Publication
18411244 | -
First Author: HÃ¥berg K
Year: 2008
Journal: J Cell Sci
Title: SNX18 is an SNX9 paralog that acts as a membrane tubulator in AP-1-positive endosomal trafficking.
Volume: 121
Issue: Pt 9
Pages: 1495-505
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Protein Domain
IPR035558 | SNX9_SH3
Type: Domain
Description: Sorting nexin 9 (SNX9) has been suggested to be involved in the endocytic process as an accessory factor []. SNX9 has binding sites for both clathrin and adaptor protein AP-2 in a low complexity region, and binds dynamin-2 (Dyn2) by its SH3 domain. SNX9 has its own membrane-binding activity, mediated by a carboxyl-terminal region containing the PX domain and the BAR domain []. Endogenous SNX9 partially co-localizes with AP-2 and Dyn2 at the plasma membrane, and over expression in K562 and HeLa cells of truncated versions of SNX9 inhibits the uptake of transferrin []. Moreover, SNX9 is required for efficient clathrin-mediated endocytosis, which suggests that it functions to regulate dynamin activity [].SNXs are Phox homology (PX) domain containing proteins that are involved in regulating membrane traffic and protein sorting in the endosomal system. SNX9 also contains a BAR and a SH3 domain. This entry represents the SH3 domain of SNX9.
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Protein Domain
IPR037425 | SNX9_BAR
Type: Domain
Description: Sorting nexin 9 (SNX9) has been suggested to be involved in the endocytic process as an accessory factor []. SNX9 has binding sites for both clathrin and adaptor protein AP-2 in a low complexity region, and binds dynamin-2 (Dyn2) by its SH3 domain. SNX9 has its own membrane-binding activity, mediated by a carboxyl-terminal region containing the PX domain and the BAR domain []. Endogenous SNX9 partially co-localizes with AP-2 and Dyn2 at the plasma membrane, and over expression in K562 and HeLa cells of truncated versions of SNX9 inhibits the uptake of transferrin []. Moreover, SNX9 is required for efficient clathrin-mediated endocytosis, which suggests that it functions to regulate dynamin activity [].SNXs are Phox homology (PX) domain containing proteins that are involved in regulating membrane traffic and protein sorting in the endosomal system. SNX9 also contains a BAR and a SH3 domain. This entry represents the BAR domain of sorting nexin-9. BAR domains are dimerization, lipid binding and curvature sensing modules found in many different proteins with diverse functions [].
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Protein Domain
IPR037426 | SNX9_PX
Type: Domain
Description: Sorting nexin 9 (SNX9) has been suggested to be involved in the endocytic process as an accessory factor []. SNX9 has binding sites for both clathrin and adaptor protein AP-2 in a low complexity region, and binds dynamin-2 (Dyn2) by its SH3 domain. SNX9 has its own membrane-binding activity, mediated by a carboxyl-terminal region containing the PX domain and the BAR domain []. Endogenous SNX9 partially co-localizes with AP-2 and Dyn2 at the plasma membrane, and over expression in K562 and HeLa cells of truncated versions of SNX9 inhibits the uptake of transferrin []. Moreover, SNX9 is required for efficient clathrin-mediated endocytosis, which suggests that it functions to regulate dynamin activity [].SNXs are Phox homology (PX) domain containing proteins that are involved in regulating membrane traffic and protein sorting in the endosomal system. SNX9 also contains a BAR and a SH3 domain. This entry represents the PX domain of sorting nexin-9. The PX domain is a phosphoinositide (PI) binding module present in many proteins with diverse functions [].
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Publication
18940612 | J:247406
First Author: Wang Q
Year: 2008
Journal: Structure
Title: Structure and plasticity of Endophilin and Sorting Nexin 9.
Volume: 16
Issue: 10
Pages: 1574-87
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Protein Domain
IPR028646 | SNX18
Type: Family
Description: Sorting nexins are a large family of evolutionarily conserved phosphoinositide-binding proteins that have roles in cargo sorting through the endosomal netwrok []. Sorting nexins contain at least a PX domain (a phospholipid-binding motif). Some nexins contain a few additional domains. Proteins in the sorting nexin 9 subfamily includes SNX9, SNX18 and SNX33 []. They are characterised by the presence of an N-terminal SH3 domain (), a PX domain that is a phosphoinositide-binding module (), and a Bin/Amphiphysin/Rvs (BAR) domain at the C terminus, which allows membrane binding and bending. They are required for progression and completion of mitosis []. This entry represents SNX18, which acts as a membrane tubulator in AP (adaptor proteins)-1-positive endosomal trafficking []. It has a similar role to SNX9 in endocytic trafficking at the plasma membrane [].
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Publication
17242350 | J:119505
First Author: Badour K
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Interaction of the Wiskott-Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells.
Volume: 104
Issue: 5
Pages: 1593-8
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Publication
29078380 | J:257220
First Author: He Q
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Large G protein α-subunit XLαs limits clathrin-mediated endocytosis and regulates tissue iron levels in vivo.
Volume: 114
Issue: 45
Pages: E9559-E9568
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Publication
23823722 | J:204751
First Author: Posor Y
Year: 2013
Journal: Nature
Title: Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate.
Volume: 499
Issue: 7457
Pages: 233-7
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Publication
19379681 | -
First Author: Frost A
Year: 2009
Journal: Cell
Title: The BAR domain superfamily: membrane-molding macromolecules.
Volume: 137
Issue: 2
Pages: 191-6
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Publication
11439176 | -
First Author: Wishart MJ
Year: 2001
Journal: Cell
Title: Phoxy lipids: revealing PX domains as phosphoinositide binding modules.
Volume: 105
Issue: 7
Pages: 817-20
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