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Search results 1 to 100 out of 141 for Socs7

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0.05s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: rat
Protein Domain
Type: Family
Description: SOCS7 is a member of the suppressor of cytokine signaling family of proteins. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation []. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Banks AS
Year: 2005
Journal: J Clin Invest
Title: Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans.
Volume: 115
Issue: 9
Pages: 2462-71
Publication
First Author: Knisz J
Year: 2009
Journal: Clin Immunol
Title: Loss of SOCS7 in mice results in severe cutaneous disease and increased mast cell activation.
Volume: 132
Issue: 2
Pages: 277-84
Publication    
First Author: Hilton DJ
Year: 2002
Journal: GenBank Submission
Title: Mus musculus SH2 domain containing SOCS box protein SOCS7 mRNA, complete cds
Pages: AF424814
Publication
First Author: Fu B
Year: 2020
Journal: Cell Death Dis
Title: PTPN14 aggravates inflammation through promoting proteasomal degradation of SOCS7 in acute liver failure.
Volume: 11
Issue: 9
Pages: 803
Publication
First Author: Martens N
Year: 2005
Journal: J Biol Chem
Title: Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation.
Volume: 280
Issue: 14
Pages: 13817-23
Protein
Organism: Mus musculus/domesticus
Length: 579  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
Publication
First Author: Lawrenson ID
Year: 2017
Journal: Cereb Cortex
Title: Cortical Layer Inversion and Deregulation of Reelin Signaling in the Absence of SOCS6 and SOCS7.
Volume: 27
Issue: 1
Pages: 576-588
Publication
First Author: Krebs DL
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Development of hydrocephalus in mice lacking SOCS7.
Volume: 101
Issue: 43
Pages: 15446-51
Publication
First Author: Simó S
Year: 2013
Journal: Dev Cell
Title: Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors.
Volume: 27
Issue: 4
Pages: 399-411
Publication  
First Author: Fairchild CL
Year: 2018
Journal: Development
Title: RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion.
Volume: 145
Issue: 3
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: Turer E
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Dunn
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: eyes
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: liver
Specimen Num: 2
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: testes
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: brain
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: heart
Specimen Num: 5
GXD Expression      
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: lung
Specimen Num: 6
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: kidney
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: eyes
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: liver
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: testes
Detected: false
Specimen Num: 10
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: testes
Detected: false
Specimen Num: 11
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: brain
Detected: false
Specimen Num: 12
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: heart
Detected: false
Specimen Num: 13
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: lung
Detected: false
Specimen Num: 14
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: kidney
Detected: false
Specimen Num: 15
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: spleen
Detected: false
Specimen Num: 16
GXD Expression    
Probe: MGI:5696644
Assay Type: Northern blot
Annotation Date: 2015-11-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5696747
Age: postnatal
Image: 1
Specimen Label: skin
Detected: false
Specimen Num: 17
GXD Expression    
Probe: MGI:6430236
Assay Type: RT-PCR
Annotation Date: 2020-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:6430413
Age: postnatal day 0
Image: S1
Specimen Label: P0
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6430236
Assay Type: RT-PCR
Annotation Date: 2020-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6430413
Age: postnatal day 7
Image: S1
Specimen Label: P7
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6430236
Assay Type: RT-PCR
Annotation Date: 2020-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716821
Stage: TS21
Assay Id: MGI:6430413
Age: embryonic day 13.5
Image: S1
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6430236
Assay Type: RT-PCR
Annotation Date: 2020-05-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716824
Stage: TS24
Assay Id: MGI:6430413
Age: embryonic day 16.5
Image: S1
Specimen Label: E16
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5696774
Age: embryonic day 12.5
Image: 5A/B
Note: Moderately high levels.
Specimen Label: 5A/B
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5696774
Age: embryonic day 15.5
Image: 5C/D
Note: Moderately high levels.
Specimen Label: 5C/D
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 7
Image: 5E/F
Note: Low to very low levels.
Specimen Label: 5E/F
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3274123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5696774
Age: embryonic day 15.5
Note: Low to very low levels.
Specimen Label: not shown
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 14
Note: Low to very low levels.
Specimen Label: not shown
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 21
Note: Low to very low levels.
Specimen Label: not shown
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal adult
Specimen Label: not shown
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3148628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal adult
Note: Expressed in early spermatids. Very low expression in maturing spermatids.
Specimen Label: not shown
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3148228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal adult
Note: Very low levels.
Specimen Label: not shown
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Ubiquitous
Stage: TS20
Assay Id: MGI:5696774
Age: embryonic day 12.5
Note: Very low levels, just above background levels of a sense control probe.
Specimen Label: not shown
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Ubiquitous
Stage: TS23
Assay Id: MGI:5696774
Age: embryonic day 15.5
Note: Very low levels, just above background levels of a sense control probe.
Specimen Label: not shown
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3554728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 7
Image: 5E/F
Note: Higher levels expression.
Specimen Label: 5E/F
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3540528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 7
Image: 5E/F
Note: Higher levels expression.
Specimen Label: 5E/F
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 7
Image: 5E/F
Note: Higher levels of expression in the hippocampal formation and in the medial habenular nuclei. Low-level expression in other brain areas.
Specimen Label: 5E/F
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 21
Image: 5G/H
Specimen Label: 5G/H
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 21
Image: 5G/H
Note: Moderately expressed in the cerebellum granular layer. Very low-level expression in other brain areas.
Specimen Label: 5G/H
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3540628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 7
Image: 5E/F
Specimen Label: 5E/F
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 7
Image: 5E/F
Specimen Label: 5E/F
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3540628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 14
Specimen Label: not shown
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 14
Specimen Label: not shown
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3540628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal day 21
Specimen Label: not shown
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2965528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal adult
Note: Very low levels.
Specimen Label: not shown
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:5696645
Assay Type: RNA in situ
Annotation Date: 2015-11-19
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2910628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5696774
Age: postnatal adult
Note: Very low levels.
Specimen Label: not shown
Detected: true
Specimen Num: 9
Publication
First Author: Krebs DL
Year: 2002
Journal: Mol Cell Biol
Title: SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.
Volume: 22
Issue: 13
Pages: 4567-78
Publication
First Author: Han JS
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: CRL5-dependent regulation of the small GTPases ARL4C and ARF6 controls hippocampal morphogenesis.
Volume: 117
Issue: 37
Pages: 23073-23084
Publication
First Author: Adissu HA
Year: 2014
Journal: Dis Model Mech
Title: Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.
Volume: 7
Issue: 5
Pages: 515-24
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14