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Search results 1 to 100 out of 136 for Sp110

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0.044s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Pan H
Year: 2005
Journal: Nature
Title: Ipr1 gene mediates innate immunity to tuberculosis.
Volume: 434
Issue: 7034
Pages: 767-72
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
GXD Expression    
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1506012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828395
Age: embryonic day 14.5
Image: euxassay_003783_03
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1506012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828395
Age: embryonic day 14.5
Image: euxassay_003783_04
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1506012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828395
Age: embryonic day 14.5
Image: euxassay_003783_05
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1506012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828395
Age: embryonic day 14.5
Image: euxassay_003783_06
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1506012
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828395
Age: embryonic day 14.5
Image: euxassay_003783_07
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647016
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:3509511
Age: embryonic day 10.5
Image: 1 - left embryo
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Num: 1
GXD Expression  
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647018
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3509511
Age: embryonic day 10.5
Image: 2 - right embryo
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Num: 2
GXD Expression  
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506832
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539802
Age: embryonic day 15.5
Image: GUDMAP:6183
Detected: true
Specimen Num: 1
Publication
First Author: Weichenhan D
Year: 2001
Journal: Mamm Genome
Title: Source and component genes of a 6-200 Mb gene cluster in the house mouse.
Volume: 12
Issue: 8
Pages: 590-4
Publication
First Author: Traut W
Year: 2001
Journal: Chromosoma
Title: Evolution of a 6-200 Mb long-range repeat cluster in the genus Mus.
Volume: 110
Issue: 4
Pages: 247-52
Publication  
First Author: De Iaco A
Year: 2020
Journal: Development
Title: DUX is a non-essential synchronizer of zygotic genome activation.
Volume: 147
Issue: 2
Publication
First Author: Lui JH
Year: 2014
Journal: Nature
Title: Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex.
Volume: 515
Issue: 7526
Pages: 264-8
Publication
First Author: He Y
Year: 2021
Journal: Aging Cell
Title: Single-cell RNA-Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation.
Volume: 20
Issue: 7
Pages: e13424
Publication        
First Author: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health
Year: 2001
Title: GenBank Record Derived Information
Publication
First Author: Archambaud C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Impact of lactobacilli on orally acquired listeriosis.
Volume: 109
Issue: 41
Pages: 16684-9
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
UniProt Feature
Begin: 1
Description: Sp110 nuclear body protein
Type: chain
End: 445
Protein
Organism: Mus musculus
Length: 445  
Fragment?: false
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Danio rerio
Allele    
Name: Sp110 nuclear body protein; wild type
Allele Type: Not Specified
ProxyCollection
Allele
Name: Sp110 nuclear body protein; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Publication categories: ProxyCollection
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Publication
First Author: Tosh K
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa.
Volume: 103
Issue: 27
Pages: 10364-10368
Publication
First Author: Cai L
Year: 2011
Journal: Med Chem
Title: Identification of proteins interacting with human SP110 during the process of viral infections.
Volume: 7
Issue: 2
Pages: 121-6
Publication
First Author: Bloch DB
Year: 2000
Journal: Mol Cell Biol
Title: Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator.
Volume: 20
Issue: 16
Pages: 6138-46
Publication
First Author: Roscioli T
Year: 2006
Journal: Nat Genet
Title: Mutations in the gene encoding the PML nuclear body protein Sp110 are associated with immunodeficiency and hepatic veno-occlusive disease.
Volume: 38
Issue: 6
Pages: 620-2
DO Term
Protein
Organism: Mus musculus
Length: 159  
Fragment?: true
Protein
Organism: Mus musculus
Length: 141  
Fragment?: false
Protein Domain
Type: Family
Description: The function of nuclear protein Sp140 is not known, though it contains several chromatin related modules such as plant homeodomain (PHD), bromodomain (BRD) and SAND domain, which suggests a role in chromatin-mediated regulation of gene expression []. It also harbours a nuclear localisation signal and a dimerisation domain (HSR or CARD domain). The PHD finger of Sp140 presents an atypical fold which does not bind to histone H3 tails but binds to peptidylprolyl isomerase Pin1. Pin1 catalyses the isomerisation of a phospho-Threonine-Proline bond in Sp140-PHD and thus may modulate Sp140 function [].Human Sp140 is an interferon inducible nuclear leukocyte-specific protein that may be involved in the pathogenesis of acute promyelocytic leukemia and viral infection []. It localises to LYSP100-associated nuclear dots and is also a component of the promyelocytic leukemia nuclear body (PML-NBs) [, ]. The Sp140 locus has been identified as a lymphocytic leukemia (CLL) risk locus [].This family also includes protein Sp140-like (SP140L) [].Sp110 is a leukocyte-specific component of the nuclear body []. It may function as a nuclear hormone receptor transcriptional coactivator that may play a role in inducing differentiation of myeloid cells []. It is also involved in resisting intracellular pathogens and functions as an important drug target for preventing intracellular pathogen diseases, such as tuberculosis, hepatic veno-occlusive disease, and intracellular cancers [, ]. Sp110 gene polymorphisms may be associated with susceptibility to tuberculosis in Chinese population []. This entry includes a group of nuclear dot-associated proteins, including Sp110/Sp140/Sp140L from humans. They are proteins with a constituent of nuclear domains, also known as nuclear dots (NDs). Sequences similar to the Sp100 homodimerization/ND-targeting region occur in several other proteins and constitute a novel protein motif, termed HSR domain (for homogeneously-staining region) [].
Protein
Organism: Mus musculus
Length: 208  
Fragment?: false
Protein
Organism: Mus musculus
Length: 348  
Fragment?: false
Protein
Organism: Mus musculus
Length: 121  
Fragment?: false
Protein
Organism: Mus musculus
Length: 135  
Fragment?: false
Protein
Organism: Mus musculus
Length: 291  
Fragment?: false
Protein
Organism: Mus musculus
Length: 211  
Fragment?: false
Protein
Organism: Mus musculus
Length: 348  
Fragment?: false
Protein
Organism: Mus musculus
Length: 229  
Fragment?: false
Protein
Organism: Mus musculus
Length: 220  
Fragment?: true
Protein
Organism: Mus musculus
Length: 212  
Fragment?: false
Protein
Organism: Mus musculus
Length: 263  
Fragment?: false
Protein
Organism: Mus musculus
Length: 343  
Fragment?: true
Protein
Organism: Mus musculus
Length: 119  
Fragment?: false
Protein
Organism: Mus musculus
Length: 59  
Fragment?: false
Protein
Organism: Mus musculus
Length: 263  
Fragment?: false
Protein
Organism: Mus musculus
Length: 116  
Fragment?: false
Protein
Organism: Mus musculus
Length: 215  
Fragment?: false