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Search results 1 to 63 out of 63 for Spaca1

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Hits by Strain

Type Details Score
Gene
81833 | SPACA1
Type: gene
Organism: human
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Gene
500432 | Spaca1
Type: gene
Organism: rat
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Gene
611635 | SPACA1
Type: gene
Organism: dog, domestic
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Gene
462877 | SPACA1
Type: gene
Organism: chimpanzee
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Gene
614884 | SPACA1
Type: gene
Organism: cattle
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Gene
421820 | SPACA1
Type: gene
Organism: chicken
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Gene
699611 | SPACA1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1914902 | Spaca1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR037878 | SPACA1
Type: Family
Description: SPACA1 (also known as SAMP32) is localized to the acrosome of spermatozoa. The acrosome is an organelle transformed from the Golgi apparatus to form a cap over the anterior portion of the spermatozoa head, which contains the sperm nucleus. Mammalian acrosomes contain digestive enzymes that degrade the ovum outer membrane (zona pellucida) to allow fusion of the sperm and ovum nuclei via the acrosomal reaction []. In mammals, the acrosome releases hyaluronidase and acrosin. Antibodies against recombinant SAMP32 inhibits both the binding and the fusion of human sperm to zona-free hamster eggs []. Male mice lacking SPACA1 are infertile, and exhibit globozoospermia-like misformed sperm heads []. SPACA1 content has been reported to be diminished in a comparison of round-headed and normal spermatozoa [].
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Publication
22949614 | J:187685
First Author: Fujihara Y
Year: 2012
Journal: Development
Title: SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia.
Volume: 139
Issue: 19
Pages: 3583-9
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Protein
Q80VM2
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: false
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Protein
Q9DA48
Organism: Mus musculus/domesticus
Length: 305  
Fragment?: false
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Protein
B1AWF2
Organism: Mus musculus/domesticus
Length: 305  
Fragment?: false
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Protein
B1AWF0
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: false
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Protein
B1AWF1
Organism: Mus musculus/domesticus
Length: 290  
Fragment?: false
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Publication
11870081 | -
First Author: Hao Z
Year: 2002
Journal: Biol Reprod
Title: SAMP32, a testis-specific, isoantigenic sperm acrosomal membrane-associated protein.
Volume: 66
Issue: 3
Pages: 735-44
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Publication
10898932 | -
First Author: Abou-Haila A
Year: 2000
Journal: Arch Biochem Biophys
Title: Mammalian sperm acrosome: formation, contents, and function.
Volume: 379
Issue: 2
Pages: 173-82
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Publication
19823175 | -
First Author: Liao TT
Year: 2009
Journal: Asian J Androl
Title: Proteome analysis of round-headed and normal spermatozoa by 2-D fluorescence difference gel electrophoresis and mass spectrometry.
Volume: 11
Issue: 6
Pages: 683-93
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Protein Coding Gene
MGP_CAROLIEiJ_G0025877 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028083 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028046 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028094 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914902 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028536 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027278 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027939 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027905 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028047 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027938 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028595 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027354 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024000 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026826 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
29065458 | J:258202
 
First Author: Fujihara Y
Year: 2017
Journal: Int J Mol Sci
Title: Human Globozoospermia-Related Gene Spata16 Is Required for Sperm Formation Revealed by CRISPR/Cas9-Mediated Mouse Models.
Volume: 18
Issue: 10
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Publication
38573307 | J:347872
   
First Author: Jin HJ
Year: 2024
Journal: Elife
Title: Disruption in CYLC1 leads to acrosome detachment, sperm head deformity, and male in/subfertility in humans and mice.
Volume: 13
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Publication
37973188 | J:342617
 
First Author: Dali O
Year: 2024
Journal: Life Sci Alliance
Title: Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure.
Volume: 7
Issue: 2
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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DO Term
DOID:0070584 | spermatogenic failure 85
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Publication
35793634 | J:326789
First Author: Zhang XZ
Year: 2022
Journal: Cell Rep
Title: The perinuclear theca protein Calicin helps shape the sperm head and maintain the nuclear structure in mice.
Volume: 40
Issue: 1
Pages: 111049
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Publication
35616329 | J:326444
 
First Author: Zhang XZ
Year: 2022
Journal: Development
Title: Loss of perinuclear theca ACTRT1 causes acrosome detachment and severe male subfertility in mice.
Volume: 149
Issue: 12
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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