Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Spermatogenesis-associated protein 22 (Spata22) is required early in meiotic prophase in both male and female germ cells. It is necessary to achieve normal synapsis and for repair of meiotic DNA double-strand breaks []. |
|
•
•
•
•
•
|
Publication |
First Author: |
La Salle S |
Year: |
2012 |
Journal: |
Biol Reprod |
Title: |
Spata22, a novel vertebrate-specific gene, is required for meiotic progress in mouse germ cells. |
Volume: |
86 |
Issue: |
2 |
Pages: |
45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Petrillo C |
Year: |
2020 |
Journal: |
Chromosoma |
Title: |
shani mutation in mouse affects splicing of Spata22 and leads to impaired meiotic recombination. |
Volume: |
129 |
Issue: |
2 |
Pages: |
161-179 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Y |
Year: |
2017 |
Journal: |
Biol Reprod |
Title: |
Meiosis-specific proteins MEIOB and SPATA22 cooperatively associate with the single-stranded DNA-binding replication protein A complex and DNA double-strand breaks. |
Volume: |
96 |
Issue: |
5 |
Pages: |
1096-1104 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
358
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
358
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
311
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hays E |
Year: |
2017 |
Journal: |
Andrology |
Title: |
Spermatogenesis associated 22 is required for DNA repair and synapsis of homologous chromosomes in mouse germ cells. |
Volume: |
5 |
Issue: |
2 |
Pages: |
299-312 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo M |
Year: |
2013 |
Journal: |
Nat Commun |
Title: |
MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination. |
Volume: |
4 |
|
Pages: |
2788 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694125 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-26 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6694901 |
Age: |
postnatal day 8 |
Image: |
8 |
|
Specimen Label: |
8-dpp testes +/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694125 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-26 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6694901 |
Age: |
postnatal day 8 |
Image: |
8 |
|
Specimen Label: |
8-dpp testes -/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694125 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-26 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6694914 |
Age: |
postnatal adult |
Image: |
8 |
|
Specimen Label: |
Meiob-/- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694125 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-26 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6694914 |
Age: |
postnatal adult |
Image: |
8 |
|
Specimen Label: |
Meioc-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694125 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-26 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6694926 |
Age: |
postnatal day 20 |
Image: |
S8 |
|
Specimen Label: |
Meioc+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694125 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-26 |
Strength: |
Not Specified |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6694926 |
Age: |
postnatal day 20 |
Image: |
S8 |
|
Specimen Label: |
Meioc-/- |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694193 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-26 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6694931 |
Age: |
postnatal |
Image: |
S9 |
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694193 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-26 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6694931 |
Age: |
postnatal |
Image: |
S9 |
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694270 |
Assay Type: |
Western blot |
Annotation Date: |
2021-04-26 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6694964 |
Age: |
postnatal adult |
Image: |
S8 |
|
Specimen Label: |
Ad +/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694270 |
Assay Type: |
Western blot |
Annotation Date: |
2021-04-26 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6694964 |
Age: |
postnatal adult |
Image: |
S8 |
|
Specimen Label: |
Ad +/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694270 |
Assay Type: |
Western blot |
Annotation Date: |
2021-04-26 |
Strength: |
Not Specified |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6694964 |
Age: |
postnatal adult |
Image: |
S8 |
|
Specimen Label: |
Ad -/- |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694125 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-26 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796222 |
|
Stage: |
TS22 |
Assay Id: |
MGI:6694901 |
Age: |
embryonic day 14.5 |
Image: |
8 |
|
Specimen Label: |
14-dpc ovaries +/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6694125 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-04-26 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796222 |
|
Stage: |
TS22 |
Assay Id: |
MGI:6694901 |
Age: |
embryonic day 14.5 |
Image: |
8 |
|
Specimen Label: |
14-dpc ovaries -/- |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1868128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692844 |
Age: |
postnatal adult |
Image: |
UC Davis_1873596 |
Note: |
vas deferens |
Specimen Label: |
UC Davis_1873596 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1868128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692844 |
Age: |
postnatal adult |
Image: |
UC Davis_1873597 |
Note: |
vas deferens |
Specimen Label: |
UC Davis_1873597 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692844 |
Age: |
postnatal adult |
Image: |
UC Davis_1873590 |
|
Specimen Label: |
UC Davis_1873590 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692844 |
Age: |
postnatal adult |
Image: |
UC Davis_1873591 |
|
Specimen Label: |
UC Davis_1873591 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1928728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692844 |
Age: |
postnatal adult |
Image: |
UC Davis_1873594 |
|
Specimen Label: |
UC Davis_1873594 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1928728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692844 |
Age: |
postnatal adult |
Image: |
UC Davis_1873595 |
|
Specimen Label: |
UC Davis_1873595 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692844 |
Age: |
postnatal adult |
Image: |
UC Davis_1873592 |
|
Specimen Label: |
UC Davis_1873592 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692844 |
Age: |
postnatal adult |
Image: |
UC Davis_1873593 |
|
Specimen Label: |
UC Davis_1873593 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3276428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692844 |
Age: |
postnatal adult |
Image: |
UC Davis_1873598 |
|
Specimen Label: |
UC Davis_1873598 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells. |
Volume: |
11 |
Issue: |
1 |
Pages: |
2055 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination. |
Volume: |
10 |
Issue: |
1 |
Pages: |
722 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Q |
Year: |
2019 |
Journal: |
Sci Adv |
Title: |
SPO16 binds SHOC1 to promote homologous recombination and crossing-over in meiotic prophase I. |
Volume: |
5 |
Issue: |
1 |
Pages: |
eaau9780 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schimenti JC |
Year: |
2018 |
Journal: |
Biol Reprod |
Title: |
Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome". |
Volume: |
99 |
Issue: |
6 |
Pages: |
1119-1128 |
|
•
•
•
•
•
|
Publication |
First Author: |
Felipe-Medina N |
Year: |
2020 |
Journal: |
Elife |
Title: |
A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1. |
Volume: |
9 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Q |
Year: |
2018 |
Journal: |
Commun Biol |
Title: |
Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis. |
Volume: |
1 |
|
Pages: |
147 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abby E |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts. |
Volume: |
7 |
|
Pages: |
10324 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Q |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Meiosis I progression in spermatogenesis requires a type of testis-specific 20S core proteasome. |
Volume: |
10 |
Issue: |
1 |
Pages: |
3387 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guan Y |
Year: |
2022 |
Journal: |
Nucleic Acids Res |
Title: |
SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. |
Volume: |
50 |
Issue: |
9 |
Pages: |
5129-5144 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ni L |
Year: |
2016 |
Journal: |
Mol Reprod Dev |
Title: |
Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models. |
Volume: |
83 |
Issue: |
12 |
Pages: |
1060-1069 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dickinson ME |
Year: |
2016 |
Journal: |
Nature |
Title: |
High-throughput discovery of novel developmental phenotypes. |
Volume: |
537 |
Issue: |
7621 |
Pages: |
508-514 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
Journal: |
Database Download |
Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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First Author: |
Bairoch A |
Year: |
1999 |
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Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Xu Y |
Year: |
2020 |
Journal: |
Biol Reprod |
Title: |
A cell-based high-content screen identifies isocotoin as a small molecule inhibitor of the meiosis-specific MEIOB-SPATA22 complex†. |
Volume: |
103 |
Issue: |
2 |
Pages: |
333-342 |
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