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Search results 1 to 74 out of 74 for Spata22

0.022s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Spermatogenesis-associated protein 22 (Spata22) is required early in meiotic prophase in both male and female germ cells. It is necessary to achieve normal synapsis and for repair of meiotic DNA double-strand breaks [].
Publication
First Author: La Salle S
Year: 2012
Journal: Biol Reprod
Title: Spata22, a novel vertebrate-specific gene, is required for meiotic progress in mouse germ cells.
Volume: 86
Issue: 2
Pages: 45
Publication
First Author: Petrillo C
Year: 2020
Journal: Chromosoma
Title: shani mutation in mouse affects splicing of Spata22 and leads to impaired meiotic recombination.
Volume: 129
Issue: 2
Pages: 161-179
Publication
First Author: Xu Y
Year: 2017
Journal: Biol Reprod
Title: Meiosis-specific proteins MEIOB and SPATA22 cooperatively associate with the single-stranded DNA-binding replication protein A complex and DNA double-strand breaks.
Volume: 96
Issue: 5
Pages: 1096-1104
Protein
Organism: Mus musculus/domesticus
Length: 358  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 358  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
Publication
First Author: Hays E
Year: 2017
Journal: Andrology
Title: Spermatogenesis associated 22 is required for DNA repair and synapsis of homologous chromosomes in mouse germ cells.
Volume: 5
Issue: 2
Pages: 299-312
Publication  
First Author: Luo M
Year: 2013
Journal: Nat Commun
Title: MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination.
Volume: 4
Pages: 2788
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression    
Probe: MGI:6694125
Assay Type: RT-PCR
Annotation Date: 2021-04-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6694901
Age: postnatal day 8
Image: 8
Specimen Label: 8-dpp testes +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6694125
Assay Type: RT-PCR
Annotation Date: 2021-04-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6694901
Age: postnatal day 8
Image: 8
Specimen Label: 8-dpp testes -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6694125
Assay Type: RT-PCR
Annotation Date: 2021-04-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6694914
Age: postnatal adult
Image: 8
Specimen Label: Meiob-/-
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6694125
Assay Type: RT-PCR
Annotation Date: 2021-04-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6694914
Age: postnatal adult
Image: 8
Specimen Label: Meioc-/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6694125
Assay Type: RT-PCR
Annotation Date: 2021-04-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6694926
Age: postnatal day 20
Image: S8
Specimen Label: Meioc+/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6694125
Assay Type: RT-PCR
Annotation Date: 2021-04-26
Strength: Not Specified
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6694926
Age: postnatal day 20
Image: S8
Specimen Label: Meioc-/-
Specimen Num: 2
GXD Expression    
Probe: MGI:6694193
Assay Type: RT-PCR
Annotation Date: 2021-04-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6694931
Age: postnatal
Image: S9
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6694193
Assay Type: RT-PCR
Annotation Date: 2021-04-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6694931
Age: postnatal
Image: S9
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6694270
Assay Type: Western blot
Annotation Date: 2021-04-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6694964
Age: postnatal adult
Image: S8
Specimen Label: Ad +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6694270
Assay Type: Western blot
Annotation Date: 2021-04-26
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6694964
Age: postnatal adult
Image: S8
Specimen Label: Ad +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6694270
Assay Type: Western blot
Annotation Date: 2021-04-26
Strength: Not Specified
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6694964
Age: postnatal adult
Image: S8
Specimen Label: Ad -/-
Specimen Num: 3
GXD Expression    
Probe: MGI:6694125
Assay Type: RT-PCR
Annotation Date: 2021-04-26
Strength: Present
Sex: Female
Emaps: EMAPS:1796222
Stage: TS22
Assay Id: MGI:6694901
Age: embryonic day 14.5
Image: 8
Specimen Label: 14-dpc ovaries +/+
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6694125
Assay Type: RT-PCR
Annotation Date: 2021-04-26
Strength: Present
Sex: Female
Emaps: EMAPS:1796222
Stage: TS22
Assay Id: MGI:6694901
Age: embryonic day 14.5
Image: 8
Specimen Label: 14-dpc ovaries -/-
Detected: true
Specimen Num: 4
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692844
Age: postnatal adult
Image: UC Davis_1873596
Note: vas deferens
Specimen Label: UC Davis_1873596
Detected: true
Specimen Num: 8
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692844
Age: postnatal adult
Image: UC Davis_1873597
Note: vas deferens
Specimen Label: UC Davis_1873597
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692844
Age: postnatal adult
Image: UC Davis_1873590
Specimen Label: UC Davis_1873590
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692844
Age: postnatal adult
Image: UC Davis_1873591
Specimen Label: UC Davis_1873591
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692844
Age: postnatal adult
Image: UC Davis_1873594
Specimen Label: UC Davis_1873594
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692844
Age: postnatal adult
Image: UC Davis_1873595
Specimen Label: UC Davis_1873595
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692844
Age: postnatal adult
Image: UC Davis_1873592
Specimen Label: UC Davis_1873592
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692844
Age: postnatal adult
Image: UC Davis_1873593
Specimen Label: UC Davis_1873593
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692844
Age: postnatal adult
Image: UC Davis_1873598
Specimen Label: UC Davis_1873598
Detected: true
Specimen Num: 1
Publication
First Author: Zhang J
Year: 2020
Journal: Nat Commun
Title: The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells.
Volume: 11
Issue: 1
Pages: 2055
Publication
First Author: Zhang J
Year: 2019
Journal: Nat Commun
Title: A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination.
Volume: 10
Issue: 1
Pages: 722
Publication
First Author: Zhang Q
Year: 2019
Journal: Sci Adv
Title: SPO16 binds SHOC1 to promote homologous recombination and crossing-over in meiotic prophase I.
Volume: 5
Issue: 1
Pages: eaau9780
Publication
First Author: Schimenti JC
Year: 2018
Journal: Biol Reprod
Title: Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".
Volume: 99
Issue: 6
Pages: 1119-1128
Publication    
First Author: Felipe-Medina N
Year: 2020
Journal: Elife
Title: A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1.
Volume: 9
Publication  
First Author: Zhang Q
Year: 2018
Journal: Commun Biol
Title: Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis.
Volume: 1
Pages: 147
Publication  
First Author: Abby E
Year: 2016
Journal: Nat Commun
Title: Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts.
Volume: 7
Pages: 10324
Publication
First Author: Zhang Q
Year: 2019
Journal: Nat Commun
Title: Meiosis I progression in spermatogenesis requires a type of testis-specific 20S core proteasome.
Volume: 10
Issue: 1
Pages: 3387
Publication
First Author: Guan Y
Year: 2022
Journal: Nucleic Acids Res
Title: SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination.
Volume: 50
Issue: 9
Pages: 5129-5144
Publication
First Author: Ni L
Year: 2016
Journal: Mol Reprod Dev
Title: Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models.
Volume: 83
Issue: 12
Pages: 1060-1069
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication
First Author: Xu Y
Year: 2020
Journal: Biol Reprod
Title: A cell-based high-content screen identifies isocotoin as a small molecule inhibitor of the meiosis-specific MEIOB-SPATA22 complex†.
Volume: 103
Issue: 2
Pages: 333-342