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Search results 1 to 100 out of 1777 for Spp1

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
6696 | SPP1
Type: gene
Organism: human
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Gene
key_19543 | SPP1
Type: gene
Organism: pig, domestic
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Gene
key_28538 | SPP1
Type: gene
Organism: sheep
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Gene
25353 | Spp1
Type: gene
Organism: rat
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Gene
478471 | SPP1
Type: gene
Organism: dog, domestic
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Gene
461366 | SPP1
Type: gene
Organism: chimpanzee
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Gene
281499 | SPP1
Type: gene
Organism: cattle
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Gene
395210 | SPP1
Type: gene
Organism: chicken
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Gene
432385 | spp1
Type: gene
Organism: zebrafish
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Gene
704930 | SPP1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:98389 | Spp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
110283621 | LOC110283621
Type: gene
Organism: human
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GXD Expression
GXD Expression
 
Probe: MGI:219266
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826110
Age: embryonic day 14.5
Image: Additional file 4 Spp1
Specimen Label: Additional file 4 Spp1
Detected: true
Specimen Num: 1
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QTL
MGI:3579880 | Drsi
Type: QTL
Organism: mouse, laboratory
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Publication
15039225 | J:89623
First Author: Aherrahrou Z
Year: 2004
Journal: Am J Pathol
Title: A locus on chromosome 7 determines dramatic up-regulation of osteopontin in dystrophic cardiac calcification in mice.
Volume: 164
Issue: 4
Pages: 1379-87
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393446
Age: postnatal day 0
Image: 7 Spp1 P0
Note: Expression was detected in hair cells; a subset co-localized with Spp1.
Specimen Label: 7 Spp1 P0
Detected: true
Specimen Num: 25
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393446
Age: postnatal day 0
Image: 7 Spp1 P0 orthogonal
Note: Expression was detected in hair cells; a subset co-localized with Spp1.
Specimen Label: 7 Spp1 P0 orthogonal
Detected: true
Specimen Num: 26
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 12
Image: 7 Spp1 P12
Note: Expression was detected in hair cells; a subset co-localized with Spp1.
Specimen Label: 7 Spp1 P12
Detected: true
Specimen Num: 27
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 12
Image: 7 Spp1 P12 orthogonal
Note: Expression was detected in hair cells; a subset co-localized with Spp1.
Specimen Label: 7 Spp1 P12 orthogonal
Detected: true
Specimen Num: 28
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 64
Image: 7 Spp1 P64
Note: Expression was detected in hair cells; a subset co-localized with Spp1.
Specimen Label: 7 Spp1 P64
Detected: true
Specimen Num: 29
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 64
Image: 7 Spp1 P64 orthogonal
Note: Expression was detected in hair cells; a subset co-localized with Spp1.
Specimen Label: 7 Spp1 P64 orthogonal
Detected: true
Specimen Num: 30
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Publication
- | J:322668
     
First Author: De Schepper S
Year: 2022
Journal: bioRxiv
Title: Perivascular SPP1 Mediates Microglial Engulfment of Synapses in Alzheimer's Disease Models
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Publication
31411676 | J:296468
First Author: Kramerova I
Year: 2019
Journal: Hum Mol Genet
Title: Spp1 (osteopontin) promotes TGFβ processing in fibroblasts of dystrophin-deficient muscles through matrix metalloproteinases.
Volume: 28
Issue: 20
Pages: 3431-3442
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Publication
38504518 | J:359488
First Author: Wang T
Year: 2024
Journal: Mol Ther
Title: SOCS3 regulates pathological retinal angiogenesis through modulating SPP1 expression in microglia and macrophages.
Volume: 32
Issue: 5
Pages: 1425-1444
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Publication
34165144 | J:317094
First Author: Kramer AC
Year: 2021
Journal: Biol Reprod
Title: SPP1 expression in the mouse uterus and placenta: implications for implantation†.
Volume: 105
Issue: 4
Pages: 892-904
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Publication
22046352 | J:178075
First Author: Peacock JD
Year: 2011
Journal: PLoS One
Title: Sox9 transcriptionally represses Spp1 to prevent matrix mineralization in maturing heart valves and chondrocytes.
Volume: 6
Issue: 10
Pages: e26769
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Publication
37160307 | J:335752
 
First Author: Li S
Year: 2023
Journal: Life Sci Alliance
Title: Vitamin C protects retinal ganglion cells via SPP1 in glaucoma and after optic nerve damage.
Volume: 6
Issue: 8
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Publication
36747024 | J:333044
First Author: De Schepper S
Year: 2023
Journal: Nat Neurosci
Title: Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
Volume: 26
Issue: 3
Pages: 406-415
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Publication
25009290 | J:247085
First Author: Rowe GC
Year: 2014
Journal: Circ Res
Title: PGC-1α induces SPP1 to activate macrophages and orchestrate functional angiogenesis in skeletal muscle.
Volume: 115
Issue: 5
Pages: 504-17
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Publication
38309272 | J:346654
First Author: Lan Y
Year: 2024
Journal: Immunity
Title: Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury.
Volume: 57
Issue: 2
Pages: 349-363.e9
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Publication
31426806 | J:341549
First Author: Yang H
Year: 2019
Journal: J Neuroinflammation
Title: Transcriptome profiling of brain myeloid cells revealed activation of Itgal, Trem1, and Spp1 in western diet-induced obesity.
Volume: 16
Issue: 1
Pages: 169
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GXD Expression
GXD Expression
   
Probe: MGI:6184187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191383
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Spp1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6184187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191383
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Spp1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6184187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191383
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Spp1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6184187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191383
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Spp1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6184187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191383
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Spp1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6184187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191383
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Spp1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6184187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191383
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Spp1
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:4949866
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393438
Age: postnatal day 70
Image: 5B
Note: Spp1 expression co-localized with the Type I hair cell marker, Tnc.
Specimen Label: 5B
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4949866
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393438
Age: postnatal day 70
Image: 5C
Note: There was no overlap of Spp1 expression with the Type II hair cell marker, Calb2.
Specimen Label: 5C
Detected: true
Specimen Num: 5
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Allele
Drsi<C3H/HeNCrl> | MGI:3579883
 
Name: DCC-related Spp1 induction; C3H/HeNCrl
Allele Type: QTL
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Genotype
Genotype
Symbol: Drsi/Drsi
Background: B6.C3-(D7Mit56-D7Mit230)
Zygosity: hm
Has Mutant Allele: true
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GXD Expression
GXD Expression
Probe: MGI:1371571
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2800323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5538830
Age: embryonic day 15.5
Image: GUDMAP:10916
Note: strong Spp1 mRNA expression in a small subset of early proximal tubules of maturing nephron stage IV only
Specimen Label: GUDMAP:10916
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:1371571
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2806123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5538830
Age: embryonic day 15.5
Image: GUDMAP:10916
Note: small number of nephrons expressed Spp1 in the collecting duct. We observed very-weak expression in single cells of some collecting duct tubules.
Specimen Label: GUDMAP:10916
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4949866
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393438
Age: postnatal day 70
Image: 5B'
Note: In the orthogonal view, Spp1 was localized lumenal to Tnc expression in the neck region of each Type I hair cell.
Specimen Label: 5B'
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4949866
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393438
Age: postnatal day 0
Image: 7 P0
Note: At P0, Spp1 was expressed in a limited number of hair cells (~60% of the Type I hair cells and 23% of immature hair cells). Hair cells were labeled by the marker Myo7a.
Specimen Label: 7 P0
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:4949866
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393438
Age: postnatal day 12
Image: 7 P12 orthogonal
Note: At P12, Spp1 was expressed in 90% of Type I hair cells. Hair cells were identified with the marker Myo7a. Only 20% of Type II hair cells were Spp1-positive.
Specimen Label: 7 P12 orthogonal
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:1371571
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2813028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5538830
Age: postnatal adult
Image: GUDMAP:10914
Note: moderate Spp1 expression in a very small number of collecting duct tubules in the cortex. These tubules co-expressed the collecting duct marker protein, Aqp2. These collecting ducts represented a very-small subset of mature cortical nephrons of the adult kidney.
Specimen Label: GUDMAP:10914
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:1371571
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2813028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5538830
Age: postnatal adult
Image: GUDMAP:10915
Note: moderate Spp1 expression in a very small number of collecting duct tubules in the cortex. These tubules co-expressed the collecting duct marker protein, Aqp2. These collecting ducts represented a very-small subset of mature cortical nephrons of the adult kidney.
Specimen Label: GUDMAP:10915
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4949866
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393438
Age: postnatal day 0
Image: 7 P0 orthogonal
Note: At P0, Spp1 was expressed in a limited number of hair cells (~60% of the Type I hair cells and 23% of immature hair cells). Hair cells were labeled by the marker Myo7a.
Specimen Label: 7 P0 orthogonal
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:4949866
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393438
Age: postnatal day 12
Image: 7 P12
Note: At P12, Spp1 was expressed in 90% of Type I hair cells. Hair cells were identified with the marker Myo7a. Only 20% of Type II hair cells were Spp1-positive.
Specimen Label: 7 P12
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:4949866
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393438
Age: postnatal day 64
Image: 7 P64
Note: At P64, Spp1 was expressed in 90% of Type I hair cells. Hair cells were identified with the marker Myo7a. Spp1 expression in Type II hair cells dropped to 4%.
Specimen Label: 7 P64
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:4949866
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393438
Age: postnatal day 64
Image: 7 P64 orthogonal
Note: At P64, Spp1 was expressed in 90% of Type I hair cells. Hair cells were identified with the marker Myo7a. Spp1 expression in Type II hair cells dropped to 4%.
Specimen Label: 7 P64 orthogonal
Detected: true
Specimen Num: 11
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Protein
Q66JX3
Organism: Mus musculus/domesticus
Length: 295  
Fragment?: false
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Publication
12847283 | -
First Author: Leali D
Year: 2003
Journal: J Immunol
Title: Osteopontin (Eta-1) and fibroblast growth factor-2 cross-talk in angiogenesis.
Volume: 171
Issue: 2
Pages: 1085-93
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Protein
Q547B5
Organism: Mus musculus/domesticus
Length: 294  
Fragment?: false
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Publication
24816281 | J:232233
First Author: Ganguly K
Year: 2014
Journal: Am J Respir Cell Mol Biol
Title: Secreted phosphoprotein 1 is a determinant of lung function development in mice.
Volume: 51
Issue: 5
Pages: 637-51
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Publication
25132354 | J:320025
First Author: Lazaro R
Year: 2015
Journal: Hepatology
Title: Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice.
Volume: 61
Issue: 1
Pages: 129-40
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Publication
9525990 | J:46863
First Author: Liaw L
Year: 1998
Journal: J Clin Invest
Title: Altered wound healing in mice lacking a functional osteopontin gene (spp1).
Volume: 101
Issue: 7
Pages: 1468-78
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Publication
37634682 | J:357557
 
First Author: Mohamed FF
Year: 2023
Journal: Bone
Title: Contributions of increased osteopontin and hypophosphatemia to dentoalveolar defects in osteomalacic Hyp mice.
Volume: 176
Pages: 116886
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Publication
36577373 | J:335751
First Author: Li S
Year: 2022
Journal: Cell Rep
Title: Secreted phosphoprotein 1 slows neurodegeneration and rescues visual function in mouse models of aging and glaucoma.
Volume: 41
Issue: 13
Pages: 111880
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Publication
24569375 | J:209722
First Author: Shan M
Year: 2014
Journal: J Clin Invest
Title: Agonistic induction of PPARγ reverses cigarette smoke-induced emphysema.
Volume: 124
Issue: 3
Pages: 1371-81
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Publication
22991301 | J:233260
First Author: Foster BL
Year: 2013
Journal: J Bone Miner Res
Title: Tooth root dentin mineralization defects in a mouse model of hypophosphatasia.
Volume: 28
Issue: 2
Pages: 271-82
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Publication
29065150 | J:247827
First Author: Quattrocelli M
Year: 2017
Journal: PLoS Genet
Title: Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury.
Volume: 13
Issue: 10
Pages: e1007070
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Publication
29313816 | J:257556
 
First Author: Foster BL
Year: 2018
Journal: Bone
Title: Osteopontin regulates dentin and alveolar bone development and mineralization.
Volume: 107
Pages: 196-207
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Publication
16980342 | J:119943
First Author: Subramanian V
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Lack of osteopontin improves cardiac function in streptozotocin-induced diabetic mice.
Volume: 292
Issue: 1
Pages: H673-83
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Publication
29717936 | J:281920
First Author: Trostel J
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Different effects of global osteopontin and macrophage osteopontin in glomerular injury.
Volume: 315
Issue: 4
Pages: F759-F768
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Publication
30199283 | J:285638
First Author: Jiang R
Year: 2019
Journal: FASEB J
Title: Milk osteopontin promotes brain development by up-regulating osteopontin in the brain in early life.
Volume: 33
Issue: 2
Pages: 1681-1694
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Publication
24871103 | J:217343
First Author: Lancha A
Year: 2014
Journal: PLoS One
Title: Osteopontin deletion prevents the development of obesity and hepatic steatosis via impaired adipose tissue matrix remodeling and reduced inflammation and fibrosis in adipose tissue and liver in mice.
Volume: 9
Issue: 5
Pages: e98398
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Publication
25525298 | J:336896
 
First Author: Marcondes MC
Year: 2014
Journal: Mediators Inflamm
Title: Osteopontin expression in the brain triggers localized inflammation and cell death when immune cells are activated by pertussis toxin.
Volume: 2014
Pages: 358218
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Publication
12506146 | J:103140
First Author: Wesson JA
Year: 2003
Journal: J Am Soc Nephrol
Title: Osteopontin is a critical inhibitor of calcium oxalate crystal formation and retention in renal tubules.
Volume: 14
Issue: 1
Pages: 139-47
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Publication
17003824 | J:136483
First Author: Yoo KH
Year: 2006
Journal: Kidney Int
Title: Osteopontin regulates renal apoptosis and interstitial fibrosis in neonatal chronic unilateral ureteral obstruction.
Volume: 70
Issue: 10
Pages: 1735-41
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Publication
29404515 | J:329841
First Author: Magdaleno F
Year: 2018
Journal: Hepatol Commun
Title: Osteopontin deletion drives hematopoietic stem cell mobilization to the liver and increases hepatic iron contributing to alcoholic liver disease.
Volume: 2
Issue: 1
Pages: 84-98
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Publication
11696588 | J:119298
First Author: Weiss JM
Year: 2001
Journal: J Exp Med
Title: Osteopontin is involved in the initiation of cutaneous contact hypersensitivity by inducing Langerhans and dendritic cell migration to lymph nodes.
Volume: 194
Issue: 9
Pages: 1219-29
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Publication
15820201 | J:162741
First Author: Speer MY
Year: 2005
Journal: Cardiovasc Res
Title: Smooth muscle cells deficient in osteopontin have enhanced susceptibility to calcification in vitro.
Volume: 66
Issue: 2
Pages: 324-33
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Publication
28453726 | J:263302
First Author: Li J
Year: 2017
Journal: Cardiovasc Res
Title: Osteopontin RNA aptamer can prevent and reverse pressure overload-induced heart failure.
Volume: 113
Issue: 6
Pages: 633-643
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Publication
30307407 | J:270498
First Author: Wei J
Year: 2019
Journal: J Clin Invest
Title: Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target.
Volume: 129
Issue: 1
Pages: 137-149
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Publication
35162963 | J:321699
 
First Author: Makishi S
Year: 2022
Journal: Int J Mol Sci
Title: Osteopontin on the Dental Implant Surface Promotes Direct Osteogenesis in Osseointegration.
Volume: 23
Issue: 3
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Publication
24558422 | J:213351
First Author: Wong TM
Year: 2014
Journal: PLoS One
Title: Respiratory syncytial virus (RSV) infection in elderly mice results in altered antiviral gene expression and enhanced pathology.
Volume: 9
Issue: 2
Pages: e88764
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Publication
23199812 | J:332273
First Author: Santamaría MH
Year: 2013
Journal: Cytokine
Title: Osteopontin-dependent regulation of Th1 and Th17 cytokine responses in Trypanosoma cruzi-infected C57BL/6 mice.
Volume: 61
Issue: 2
Pages: 491-8
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Publication
26438603 | J:226624
First Author: Lee SH
Year: 2015
Journal: Carcinogenesis
Title: Ablation of osteopontin suppresses N-methyl-N-nitrosourea and Helicobacter pylori-induced gastric cancer development in mice.
Volume: 36
Issue: 12
Pages: 1550-60
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Publication
18266970 | J:142483
First Author: Chakraborty G
Year: 2008
Journal: J Cell Mol Med
Title: Down-regulation of osteopontin attenuates breast tumour progression in vivo.
Volume: 12
Issue: 6A
Pages: 2305-18
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Publication
25151457 | J:217765
 
First Author: Chan JL
Year: 2014
Journal: Exp Neurol
Title: Osteopontin expression in acute immune response mediates hippocampal synaptogenesis and adaptive outcome following cortical brain injury.
Volume: 261
Pages: 757-71
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Publication
14977630 | J:108144
First Author: Berman JS
Year: 2004
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Altered bleomycin-induced lung fibrosis in osteopontin-deficient mice.
Volume: 286
Issue: 6
Pages: L1311-8
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Publication
18449212 | J:141700
First Author: Schulz G
Year: 2008
Journal: J Invest Dermatol
Title: Regulated osteopontin expression by dendritic cells decisively affects their migratory capacity.
Volume: 128
Issue: 10
Pages: 2541-4
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Publication
25867766 | J:222619
First Author: Park JW
Year: 2015
Journal: Lab Invest
Title: Osteopontin depletion decreases inflammation and gastric epithelial proliferation during Helicobacter pylori infection in mice.
Volume: 95
Issue: 6
Pages: 660-71
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Publication
21562757 | J:172597
First Author: Kiefer FW
Year: 2011
Journal: Diabetologia
Title: Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice.
Volume: 54
Issue: 8
Pages: 2132-42
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Publication
35213222 | J:329156
First Author: Khamissi FZ
Year: 2022
Journal: Sci Adv
Title: Identification of kidney injury released circulating osteopontin as causal agent of respiratory failure.
Volume: 8
Issue: 8
Pages: eabm5900
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Publication
12466120 | J:113585
First Author: Steitz SA
Year: 2002
Journal: Am J Pathol
Title: Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification.
Volume: 161
Issue: 6
Pages: 2035-46
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Publication
27484115 | J:322880
 
First Author: Lin J
Year: 2016
Journal: Sci Rep
Title: Osteopontin Deficiency Alters Biliary Homeostasis and Protects against Gallstone Formation.
Volume: 6
Pages: 30215
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Publication
18174176 | J:133795
First Author: Kang JA
Year: 2008
Journal: J Biol Chem
Title: Osteopontin regulates actin cytoskeleton and contributes to cell proliferation in primary erythroblasts.
Volume: 283
Issue: 11
Pages: 6997-7006
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Publication
28254837 | J:241949
First Author: Guidi N
Year: 2017
Journal: EMBO J
Title: Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells.
Volume: 36
Issue: 7
Pages: 840-853
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Publication
18006856 | J:159820
First Author: Duvall CL
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: The role of osteopontin in recovery from hind limb ischemia.
Volume: 28
Issue: 2
Pages: 290-5
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Publication
21737140 | J:177212
First Author: Yang H
Year: 2011
Journal: Mol Immunol
Title: Clearance of Propionibacterium acnes by kupffer cells is regulated by osteopontin through modulating the expression of p47phox.
Volume: 48
Issue: 15-16
Pages: 2019-26
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Publication
23935934 | J:336840
First Author: Kumar S
Year: 2013
Journal: PLoS One
Title: Functional characterization of stromal osteopontin in melanoma progression and metastasis.
Volume: 8
Issue: 7
Pages: e69116
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Publication
21514415 | J:171594
First Author: Sabo-Attwood T
Year: 2011
Journal: Am J Pathol
Title: Osteopontin modulates inflammation, mucin production, and gene expression signatures after inhalation of asbestos in a murine model of fibrosis.
Volume: 178
Issue: 5
Pages: 1975-85
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Publication
27026194 | J:336834
 
First Author: Zhao K
Year: 2016
Journal: Sci Rep
Title: Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response.
Volume: 6
Pages: 23771
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Publication
29957058 | J:336877
First Author: Chang J
Year: 2019
Journal: FASEB J
Title: Chemotherapy-generated cell debris stimulates colon carcinoma tumor growth via osteopontin.
Volume: 33
Issue: 1
Pages: 114-125
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Publication
21103061 | J:166990
First Author: Chapman J
Year: 2010
Journal: PLoS One
Title: Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice.
Volume: 5
Issue: 11
Pages: e13959
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Publication
20008129 | J:156488
First Author: Seier AM
Year: 2010
Journal: Am J Pathol
Title: Antigen-specific induction of osteopontin contributes to the chronification of allergic contact dermatitis.
Volume: 176
Issue: 1
Pages: 246-58
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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