Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
Not Specified |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Huynh KM |
Year: |
2020 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Sprr2f protects against renal injury by decreasing the level of reactive oxygen species in female mice. |
Volume: |
319 |
Issue: |
5 |
Pages: |
F876-F884 |
|
•
•
•
•
•
|
Publication |
First Author: |
Contreras CM |
Year: |
2010 |
Journal: |
Dis Model Mech |
Title: |
Lkb1 inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy. |
Volume: |
3 |
Issue: |
3-4 |
Pages: |
181-93 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Song HJ |
Year: |
1999 |
Journal: |
Genomics |
Title: |
Mouse Sprr2 genes: a clustered family of genes showing differential expression in epithelial tissues. |
Volume: |
55 |
Issue: |
1 |
Pages: |
28-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Patel S |
Year: |
2003 |
Journal: |
Mamm Genome |
Title: |
Mouse Sprr locus: a tandem array of coordinately regulated genes. |
Volume: |
14 |
Issue: |
2 |
Pages: |
140-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hong SH |
Year: |
2004 |
Journal: |
Mol Cells |
Title: |
Estrogen regulates the expression of the small proline-rich 2 gene family in the mouse uterus. |
Volume: |
17 |
Issue: |
3 |
Pages: |
477-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gibbs S |
Year: |
1993 |
Journal: |
Genomics |
Title: |
Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins. |
Volume: |
16 |
Issue: |
3 |
Pages: |
630-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee HJ |
Year: |
2009 |
Journal: |
Dev Dyn |
Title: |
Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern. |
Volume: |
238 |
Issue: |
4 |
Pages: |
812-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Günschmann C |
Year: |
2013 |
Journal: |
Dev Cell |
Title: |
Insulin/IGF-1 controls epidermal morphogenesis via regulation of FoxO-mediated p63 inhibition. |
Volume: |
26 |
Issue: |
2 |
Pages: |
176-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rutledge EA |
Year: |
2017 |
Journal: |
Development |
Title: |
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. |
Volume: |
144 |
Issue: |
17 |
Pages: |
3177-3188 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nagarajan P |
Year: |
2010 |
Journal: |
J Cell Sci |
Title: |
Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators. |
Volume: |
123 |
Issue: |
Pt 20 |
Pages: |
3566-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar V |
Year: |
2015 |
Journal: |
J Cell Biol |
Title: |
A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. |
Volume: |
211 |
Issue: |
5 |
Pages: |
1057-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Martin N |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
Long-range comparison of human and mouse Sprr loci to identify conserved noncoding sequences involved in coordinate regulation. |
Volume: |
14 |
Issue: |
12 |
Pages: |
2430-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6506581 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-02-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:2769723 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6506795 |
Age: |
embryonic day 15.5 |
|
Note: |
Expression is seen in the ureteric bud stalk. |
Specimen Label: |
2 - Category 5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
96
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoo JY |
Year: |
2018 |
Journal: |
BMC Cancer |
Title: |
MIG-6 suppresses endometrial epithelial cell proliferation by inhibiting phospho-AKT. |
Volume: |
18 |
Issue: |
1 |
Pages: |
605 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Diego H Castrillon |
Allele Type: |
Transgenic |
Attribute String: |
Recombinase |
|
•
•
•
•
•
|
Strain |
Attribute String: |
Not specified |
|
•
•
•
•
•
|
Publication |
First Author: |
Akbay EA |
Year: |
2013 |
Journal: |
Oncogene |
Title: |
Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis. |
Volume: |
32 |
Issue: |
17 |
Pages: |
2211-9 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 2, Diego H Castrillon |
Allele Type: |
Transgenic |
Attribute String: |
Recombinase |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakada Y |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
The LKB1 tumor suppressor as a biomarker in mouse and human tissues. |
Volume: |
8 |
Issue: |
9 |
Pages: |
e73449 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoo JY |
Year: |
2018 |
Journal: |
Oncogene |
Title: |
MIG-6 negatively regulates STAT3 phosphorylation in uterine epithelial cells. |
Volume: |
37 |
Issue: |
2 |
Pages: |
255-262 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koivisto CS |
Year: |
2020 |
Journal: |
Neoplasia |
Title: |
Evaluating the efficacy of enzalutamide and the development of resistance in a preclinical mouse model of type-I endometrial carcinoma. |
Volume: |
22 |
Issue: |
10 |
Pages: |
484-496 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li HD |
Year: |
2020 |
Journal: |
JCI Insight |
Title: |
A PoleP286R mouse model of endometrial cancer recapitulates high mutational burden and immunotherapy response. |
Volume: |
5 |
Issue: |
14 |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, transgenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Stk11/Stk11 Tg(Sprr2f-cre)1Dcas/? |
Background: |
involves: 129S6/SvEvTac * FVB/N |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen J |
Year: |
2010 |
Journal: |
Urology |
Title: |
2,8-dihydroxyadenine nephrolithiasis induces developmental stage-specific alterations in gene expression in mouse kidney. |
Volume: |
75 |
Issue: |
4 |
Pages: |
914-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mesa AM |
Year: |
2020 |
Journal: |
Physiol Genomics |
Title: |
Mice lacking uterine enhancer of zeste homolog 2 have transcriptomic changes associated with uterine epithelial proliferation. |
Volume: |
52 |
Issue: |
2 |
Pages: |
81-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sahoo SS |
Year: |
2022 |
Journal: |
J Clin Invest |
Title: |
FOXA2 suppresses endometrial carcinogenesis and epithelial-mesenchymal transition by regulating enhancer activity. |
Volume: |
132 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Guimarães-Young A |
Year: |
2016 |
Journal: |
Dev Biol |
Title: |
Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and function. |
Volume: |
414 |
Issue: |
2 |
Pages: |
219-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Teasley HE |
Year: |
2019 |
Journal: |
Biochem Biophys Res Commun |
Title: |
A calcium-dependent phospholipase A2 (cPLA2) expression is regulated by MIG-6 during endometrial tumorigenesis. |
Volume: |
511 |
Issue: |
1 |
Pages: |
129-134 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Sprr2f-cre)1Dcas/? |
Background: |
involves: 129S4/SvJaeSor * FVB |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Sprr2f-cre)2Dcas/? |
Background: |
involves: 129S4/SvJaeSor * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Peña CG |
Year: |
2015 |
Journal: |
J Clin Invest |
Title: |
LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment. |
Volume: |
125 |
Issue: |
11 |
Pages: |
4063-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Castel P |
Year: |
2016 |
Journal: |
Sci Transl Med |
Title: |
Somatic PIK3CA mutations as a driver of sporadic venous malformations. |
Volume: |
8 |
Issue: |
332 |
Pages: |
332ra42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Caserta E |
Year: |
2015 |
Journal: |
Genes Dev |
Title: |
Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo. |
Volume: |
29 |
Issue: |
16 |
Pages: |
1707-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cuevas IC |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Fbxw7 is a driver of uterine carcinosarcoma by promoting epithelial-mesenchymal transition. |
Volume: |
116 |
Issue: |
51 |
Pages: |
25880-25890 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|