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Search results 1 to 100 out of 700 for Sqstm1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:3506375
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Strong
Sex: Female
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6513134
Age: embryonic day 15.5
Image: 5 - Sqstm1
Specimen Label: 5 - Sqstm1
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3506375
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3152723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6513134
Age: embryonic day 15.5
Image: 8D - Sqstm1
Note: Expression is seen in proximity to the nephric duct and ureter insertions sites where the bladder neck joins the urethra.
Specimen Label: 8D - Sqstm1
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3506375
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Present
Sex: Female
Emaps: EMAPS:3155323
Pattern: Diffuse
Stage: TS23
Assay Id: MGI:6513134
Age: embryonic day 15.5
Image: 5 - Sqstm1
Note: Diffuse, regional expression is seen in the ventral urethra.
Specimen Label: 5 - Sqstm1
Detected: true
Specimen Num: 1
Publication
First Author: Eino A
Year: 2015
Journal: J Cell Sci
Title: Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells.
Volume: 128
Issue: 23
Pages: 4453-61
Publication
First Author: Zhou B
Year: 2020
Journal: Nat Microbiol
Title: Extracellular SQSTM1 mediates bacterial septic death in mice through insulin receptor signalling.
Volume: 5
Issue: 12
Pages: 1576-1587
Publication
First Author: Liang D
Year: 2022
Journal: Autophagy
Title: m6A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin.
Volume: 18
Issue: 6
Pages: 1318-1337
Publication
First Author: Hadano S
Year: 2016
Journal: Hum Mol Genet
Title: Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.
Volume: 25
Issue: 15
Pages: 3321-3340
Publication  
First Author: Seibenhener ML
Year: 2013
Journal: Behav Brain Res
Title: Behavioral effects of SQSTM1/p62 overexpression in mice: support for a mitochondrial role in depression and anxiety.
Volume: 248
Pages: 94-103
Publication      
First Author: Kageyama S
Year: 2018
Journal: Mol Cell Biol
Title: Negative regulation of the Keap1-Nrf2 pathway by a p62/Sqstm1 splicing variant.
Publication
First Author: Okada K
Year: 2009
Journal: Hepatol Res
Title: The alpha-glucosidase inhibitor acarbose prevents obesity and simple steatosis in sequestosome 1/A170/p62 deficient mice.
Volume: 39
Issue: 5
Pages: 490-500
Publication
First Author: Tabuchi K
Year: 2010
Journal: Neuroscience
Title: Cochlear protection from acoustic injury by inhibitors of p38 mitogen-activated protein kinase and sequestosome 1 stress protein.
Volume: 166
Issue: 2
Pages: 665-70
Publication
First Author: Ohtsuka S
Year: 2014
Journal: Eur J Immunol
Title: SQSTM1/p62/A170 regulates the severity of Legionella pneumophila pneumonia by modulating inflammasome activity.
Volume: 44
Issue: 4
Pages: 1084-92
Publication
First Author: Sugimoto R
Year: 2010
Journal: J Cell Mol Med
Title: Enhanced neointimal hyperplasia and carotid artery remodelling in sequestosome 1 deficient mice.
Volume: 14
Issue: 6B
Pages: 1546-54
Publication
First Author: Daroszewska A
Year: 2011
Journal: Hum Mol Genet
Title: A point mutation in the ubiquitin-associated domain of SQSMT1 is sufficient to cause a Paget's disease-like disorder in mice.
Volume: 20
Issue: 14
Pages: 2734-44
Publication  
First Author: Daroszewska A
Year: 2018
Journal: Dis Model Mech
Title: Zoledronic acid prevents pagetic-like lesions and accelerated bone loss in the p62P394L mouse model of Paget's disease.
Volume: 11
Issue: 9
Publication
First Author: Sarkar C
Year: 2014
Journal: Autophagy
Title: Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury.
Volume: 10
Issue: 12
Pages: 2208-22
Publication  
First Author: Sebastiani A
Year: 2017
Journal: Front Neurosci
Title: Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice.
Volume: 11
Pages: 678
Publication  
First Author: Mitsui S
Year: 2022
Journal: Neurochem Int
Title: SQSTM1, a protective factor of SOD1-linked motor neuron disease, regulates the accumulation and distribution of ubiquitinated protein aggregates in neuron.
Volume: 158
Pages: 105364
Publication
First Author: Mitsui S
Year: 2018
Journal: Mol Brain
Title: Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model.
Volume: 11
Issue: 1
Pages: 30
Publication  
First Author: Yang Y
Year: 2022
Journal: Front Immunol
Title: m6A eraser FTO modulates autophagy by targeting SQSTM1/P62 in the prevention of canagliflozin against renal fibrosis.
Volume: 13
Pages: 1094556
Publication
First Author: Williams JA
Year: 2012
Journal: PLoS One
Title: Tissue specific induction of p62/Sqstm1 by farnesoid X receptor.
Volume: 7
Issue: 8
Pages: e43961
Publication
First Author: Hubbs AF
Year: 2016
Journal: Am J Pathol
Title: Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity.
Volume: 186
Issue: 11
Pages: 2887-2908
Publication
First Author: Fang C
Year: 2021
Journal: Autophagy
Title: SSH1 impedes SQSTM1/p62 flux and MAPT/Tau clearance independent of CFL (cofilin) activation.
Volume: 17
Issue: 9
Pages: 2144-2165
Publication
First Author: Khan MM
Year: 2014
Journal: Autophagy
Title: Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors.
Volume: 10
Issue: 1
Pages: 123-36
Publication    
First Author: Chao X
Year: 2021
Journal: Autophagy
Title: An unexpected tumor suppressor role of SQSTM1/p62 in liver tumorigenesis.
Pages: 1-3
Publication
First Author: Lee DH
Year: 2020
Journal: Autophagy
Title: SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity.
Volume: 16
Issue: 11
Pages: 1949-1973
Publication
First Author: Teramachi J
Year: 2014
Journal: J Bone Miner Res
Title: Increased IL-6 expression in osteoclasts is necessary but not sufficient for the development of Paget's disease of bone.
Volume: 29
Issue: 6
Pages: 1456-65
Publication
First Author: Yamada T
Year: 2019
Journal: Autophagy
Title: SQSTM1/p62 promotes mitochondrial ubiquitination independently of PINK1 and PRKN/parkin in mitophagy.
Volume: 15
Issue: 11
Pages: 2012-2018
Publication
First Author: Salazar G
Year: 2020
Journal: Autophagy
Title: SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence.
Volume: 16
Issue: 6
Pages: 1092-1110
Publication
First Author: Wang B
Year: 2018
Journal: Autophagy
Title: The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway.
Volume: 14
Issue: 5
Pages: 796-811
Publication
First Author: Zhang XW
Year: 2020
Journal: Autophagy
Title: Disrupting the TRIB3-SQSTM1 interaction reduces liver fibrosis by restoring autophagy and suppressing exosome-mediated HSC activation.
Volume: 16
Issue: 5
Pages: 782-796
Allele
Name: sequestosome 1; targeted mutation 1c, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Okazaki M
Year: 1999
Journal: Genomics
Title: Cloning, expression profile, and genomic organization of the mouse STAP/A170 gene.
Volume: 60
Issue: 1
Pages: 87-95
Publication
First Author: Huang J
Year: 2018
Journal: Cancer Cell
Title: Adipocyte p62/SQSTM1 Suppresses Tumorigenesis through Opposite Regulations of Metabolism in Adipose Tissue and Tumor.
Volume: 33
Issue: 4
Pages: 770-784.e6
Publication
First Author: Harada H
Year: 2013
Journal: J Neurosci
Title: Deficiency of p62/Sequestosome 1 causes hyperphagia due to leptin resistance in the brain.
Volume: 33
Issue: 37
Pages: 14767-77
Publication
First Author: Honda A
Year: 2018
Journal: Endocr J
Title: Normal pancreatic β-cell function in mice with RIP-Cre-mediated inactivation of p62/SQSTM1.
Volume: 65
Issue: 1
Pages: 83-89
Publication
First Author: Ono M
Year: 2022
Journal: Aging Cell
Title: Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy.
Volume: 21
Issue: 7
Pages: e13615
Publication
First Author: Ma Y
Year: 2020
Journal: iScience
Title: SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12.
Volume: 23
Issue: 8
Pages: 101428
Publication  
First Author: Miura I
Year: 2022
Journal: Front Physiol
Title: p62/Sqstm1 rescue in muscle retards the progression of steatohepatitis in p62/Sqstm1-null mice fed a high-fat diet.
Volume: 13
Pages: 993995
Publication
First Author: Li X
Year: 2021
Journal: Exp Mol Med
Title: Pituitary P62 deficiency leads to female infertility by impairing luteinizing hormone production.
Volume: 53
Issue: 8
Pages: 1238-1249
Publication  
First Author: Tominaga T
Year: 2017
Journal: Neurosci Lett
Title: Sequestosome 1 (SQSTM1/p62) maintains protein folding capacity under endoplasmic reticulum stress in mouse hypothalamic organotypic culture.
Volume: 656
Pages: 103-107
Publication
First Author: Zach F
Year: 2018
Journal: J Biol Chem
Title: p62/sequestosome 1 deficiency accelerates osteoclastogenesis in vitro and leads to Paget's disease-like bone phenotypes in mice.
Volume: 293
Issue: 24
Pages: 9530-9541
Publication
First Author: Nguyen TD
Year: 2019
Journal: Blood
Title: Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy.
Volume: 133
Issue: 2
Pages: 168-179
Publication      
First Author: Lacava G
Year: 2019
Journal: J Cell Physiol
Title: P62 deficiency shifts mesenchymal/stromal stem cell commitment toward adipogenesis and disrupts bone marrow homeostasis in aged mice.
Publication
First Author: Hiruma Y
Year: 2008
Journal: Hum Mol Genet
Title: A SQSTM1/p62 mutation linked to Paget's disease increases the osteoclastogenic potential of the bone microenvironment.
Volume: 17
Issue: 23
Pages: 3708-19
Publication  
First Author: Keller C
Year: 2022
Journal: Front Pharmacol
Title: Impact of the Endocannabinoid System on Bone Formation and Remodeling in p62 KO Mice.
Volume: 13
Pages: 858215
Publication  
First Author: Keller C
Year: 2022
Journal: Cells
Title: Behavioral Studies of p62 KO Animals with Implications of a Modulated Function of the Endocannabinoid System.
Volume: 11
Issue: 9
Publication
First Author: Lahiri P
Year: 2016
Journal: PLoS One
Title: p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies.
Volume: 11
Issue: 8
Pages: e0161083
Publication
First Author: Martin P
Year: 2006
Journal: EMBO J
Title: The signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammation.
Volume: 25
Issue: 15
Pages: 3524-33
Publication
First Author: Qian H
Year: 2023
Journal: Cell Mol Gastroenterol Hepatol
Title: Loss of SQSTM1/p62 Induces Obesity and Exacerbates Alcohol-Induced Liver Injury in Aged Mice.
Volume: 15
Issue: 5
Pages: 1027-1049
Publication
First Author: Kageyama S
Year: 2021
Journal: Nat Commun
Title: p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response.
Volume: 12
Issue: 1
Pages: 16
Publication
First Author: Geetha T
Year: 2002
Journal: FEBS Lett
Title: Structure and functional properties of the ubiquitin binding protein p62.
Volume: 512
Issue: 1-3
Pages: 19-24
Publication
First Author: Hiruma Y
Year: 2009
Journal: Blood
Title: Increased signaling through p62 in the marrow microenvironment increases myeloma cell growth and osteoclast formation.
Volume: 113
Issue: 20
Pages: 4894-902
Publication
First Author: Lee M
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Triage of oxidation-prone proteins by Sqstm1/p62 within the mitochondria.
Volume: 413
Issue: 1
Pages: 122-7
Publication
First Author: Seibenhener ML
Year: 2013
Journal: Biochim Biophys Acta
Title: A role for sequestosome 1/p62 in mitochondrial dynamics, import and genome integrity.
Volume: 1833
Issue: 3
Pages: 452-9
Publication
First Author: Wei H
Year: 2014
Journal: Genes Dev
Title: p62/SQSTM1 synergizes with autophagy for tumor growth in vivo.
Volume: 28
Issue: 11
Pages: 1204-16
Publication
First Author: Abdulrahman BA
Year: 2013
Journal: J Biol Chem
Title: Depletion of the ubiquitin-binding adaptor molecule SQSTM1/p62 from macrophages harboring cftr ΔF508 mutation improves the delivery of Burkholderia cenocepacia to the autophagic machinery.
Volume: 288
Issue: 3
Pages: 2049-58
Publication
First Author: Teramachi J
Year: 2016
Journal: Leukemia
Title: Blocking the ZZ domain of sequestosome1/p62 suppresses myeloma growth and osteoclast formation in vitro and induces dramatic bone formation in myeloma-bearing bones in vivo.
Volume: 30
Issue: 2
Pages: 390-8
Publication
First Author: Taniguchi K
Year: 2016
Journal: FEBS Lett
Title: p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer.
Volume: 590
Issue: 15
Pages: 2375-97
Publication
First Author: Agas D
Year: 2020
Journal: J Cell Physiol
Title: Loss of p62 impairs bone turnover and inhibits PTH-induced osteogenesis.
Volume: 235
Issue: 10
Pages: 7516-7529
Publication  
First Author: Somlapura M
Year: 2021
Journal: Int J Mol Sci
Title: Different Roles of p62 (SQSTM1) Isoforms in Keratin-Related Protein Aggregation.
Volume: 22
Issue: 12
Publication
First Author: Sukseree S
Year: 2018
Journal: J Dermatol Sci
Title: Suppression of autophagy perturbs turnover of sequestosome-1/p62 in Merkel cells but not in keratinocytes.
Volume: 90
Issue: 2
Pages: 209-211
GXD Expression    
Probe: MGI:1205773
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1205775
Age: postnatal week 6-8
Image: st97_669
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1205773
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1205775
Age: postnatal week 6-8
Image: st97_669
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1205773
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1205775
Age: postnatal week 6-8
Image: st97_669
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1205773
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1205775
Age: postnatal week 6-8
Image: st97_669
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1205773
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1205775
Age: postnatal week 6-8
Image: st97_669
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1205773
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1205775
Age: postnatal week 6-8
Image: st97_669
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1205773
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1205775
Age: postnatal week 6-8
Image: st97_669
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1205773
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1205775
Age: postnatal week 6-8
Image: st97_669
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1205773
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1205775
Age: postnatal week 6-8
Image: st97_669
Specimen Label: None
Detected: true
Specimen Num: 9