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Search results 1 to 100 out of 122 for Srcin1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: SRC kinase signalling inhibitor 1 (also known as SNAP-25-interacting protein, SNIP) acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signalling, leading to impaired cell spreading and migration [, ]. It regulates dendritic spine morphology []. It is involved in calcium-dependent exocytosis and may play a role in neurotransmitter release or synapse maintenance [, ].
Publication
First Author: Di Stefano P
Year: 2007
Journal: EMBO J
Title: p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity.
Volume: 26
Issue: 12
Pages: 2843-55
Publication
First Author: Ito H
Year: 2008
Journal: J Neurochem
Title: Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex.
Volume: 107
Issue: 1
Pages: 61-72
Publication
First Author: Jaworski J
Year: 2009
Journal: Neuron
Title: Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.
Volume: 61
Issue: 1
Pages: 85-100
Publication
First Author: Di Stefano P
Year: 2004
Journal: Mol Biol Cell
Title: P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading.
Volume: 15
Issue: 2
Pages: 787-800
Protein
Organism: Mus musculus/domesticus
Length: 1250  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1205  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1225  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1357  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1174  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1198  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1055  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1217  
Fragment?: false
Publication
First Author: Chin LS
Year: 2000
Journal: J Biol Chem
Title: SNIP, a novel SNAP-25-interacting protein implicated in regulated exocytosis.
Volume: 275
Issue: 2
Pages: 1191-200
Publication
First Author: Damez-Werno DM
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Histone arginine methylation in cocaine action in the nucleus accumbens.
Volume: 113
Issue: 34
Pages: 9623-8
Publication  
First Author: Camera M
Year: 2022
Journal: Front Neurosci
Title: p140Cap Controls Female Fertility in Mice Acting via Glutamatergic Afference on Hypothalamic Gonadotropin-Releasing Hormone Neurons.
Volume: 16
Pages: 744693
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Repetto D
Year: 2014
Journal: J Neurosci
Title: p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.
Volume: 34
Issue: 4
Pages: 1542-53
GXD Expression      
Probe: MGI:6416539
Assay Type: RT-PCR
Annotation Date: 2020-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3746923
Stage: TS23
Assay Id: MGI:6416563
Age: embryonic day 15.5
Specimen Label: LGE CGE
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6416539
Assay Type: RT-PCR
Annotation Date: 2020-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747023
Stage: TS23
Assay Id: MGI:6416563
Age: embryonic day 15.5
Specimen Label: LGE CGE
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6416539
Assay Type: RT-PCR
Annotation Date: 2020-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747123
Stage: TS23
Assay Id: MGI:6416563
Age: embryonic day 15.5
Specimen Label: MGE
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6416539
Assay Type: RT-PCR
Annotation Date: 2020-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747023
Stage: TS23
Assay Id: MGI:6416564
Age: embryonic day 15.5
Specimen Label: LGE CGE
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6416539
Assay Type: RT-PCR
Annotation Date: 2020-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3746923
Stage: TS23
Assay Id: MGI:6416564
Age: embryonic day 15.5
Specimen Label: LGE CGE
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6416539
Assay Type: RT-PCR
Annotation Date: 2020-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747123
Stage: TS23
Assay Id: MGI:6416564
Age: embryonic day 15.5
Specimen Label: MGE
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6416539
Assay Type: RT-PCR
Annotation Date: 2020-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:6416564
Age: embryonic day 15.5
Specimen Label: CTX
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125119
Specimen Label: JAX_1125119
Detected: true
Specimen Num: 16
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125139
Note: kidney
Specimen Label: JAX_1125139
Detected: true
Specimen Num: 26
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125165
Specimen Label: JAX_1125165
Detected: true
Specimen Num: 13
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125153
Specimen Label: JAX_1125153
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125143
Specimen Label: JAX_1125143
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1706828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125125
Specimen Label: JAX_1125125
Detected: true
Specimen Num: 19
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1925228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125131
Specimen Label: JAX_1125131
Detected: true
Specimen Num: 22
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1898428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125161
Specimen Label: JAX_1125161
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1753628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125147
Specimen Label: JAX_1125147
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125149
Specimen Label: JAX_1125149
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125151
Specimen Label: JAX_1125151
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125123
Specimen Label: JAX_1125123
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1685328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125133
Specimen Label: JAX_1125133
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:6416537
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6416572
Age: embryonic day 12.5
Specimen Label: S2B
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125121
Specimen Label: JAX_1125121
Detected: true
Specimen Num: 17
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125135
Specimen Label: JAX_1125135
Detected: true
Specimen Num: 24
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125157
Specimen Label: JAX_1125157
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125129
Specimen Label: JAX_1125129
Detected: true
Specimen Num: 21
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125145
Specimen Label: JAX_1125145
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125141
Specimen Label: JAX_1125141
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125159
Specimen Label: JAX_1125159
Detected: true
Specimen Num: 10
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125137
Specimen Label: JAX_1125137
Detected: true
Specimen Num: 25
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125127
Specimen Label: JAX_1125127
Detected: true
Specimen Num: 20
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125155
Specimen Label: JAX_1125155
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125167
Specimen Label: JAX_1125167
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125163
Specimen Label: JAX_1125163
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692318
Age: postnatal adult
Image: JAX_1125115
Specimen Label: JAX_1125115
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:6416537
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3671620
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6416572
Age: embryonic day 12.5
Note: More intense expression, compared to the ventricular zone.
Specimen Label: S2B
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6416537
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3747120
Pattern: Graded
Stage: TS20
Assay Id: MGI:6416572
Age: embryonic day 12.5
Note: Expressed with a major intensity gradient in the subventricular zone, compared to the ventricular zone.
Specimen Label: S2B
Detected: true
Specimen Num: 1
Publication    
First Author: Croci L
Year: 1998
Journal: GenBank Submission
Title: Mus msuculus P140 (P140) mRNA, complete cds
Pages: AF040944
Publication    
First Author: Bossolasco M
Year: 1999
Journal: GenBank Submission
Title: Mus musculus unknown protein mRNA, complete cds
Pages: U59873
Publication
First Author: Guo A
Year: 2014
Journal: Mol Cell Proteomics
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
Volume: 13
Issue: 1
Pages: 372-87
Publication
First Author: Tafoya LC
Year: 2006
Journal: J Neurosci
Title: Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons.
Volume: 26
Issue: 30
Pages: 7826-38
Publication
First Author: Fossati G
Year: 2015
Journal: Cell Death Differ
Title: Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.
Volume: 22
Issue: 9
Pages: 1425-36
Publication  
First Author: Alfieri A
Year: 2017
Journal: Front Mol Neurosci
Title: Synaptic Interactome Mining Reveals p140Cap as a New Hub for PSD Proteins Involved in Psychiatric and Neurological Disorders.
Volume: 10
Pages: 212
Publication
First Author: Li MY
Year: 2017
Journal: Neuron
Title: A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.
Volume: 94
Issue: 6
Pages: 1155-1172.e8
Publication
First Author: Yang Y
Year: 2015
Journal: Cell Res
Title: Endophilin A1 regulates dendritic spine morphogenesis and stability through interaction with p140Cap.
Volume: 25
Issue: 4
Pages: 496-516
Publication
First Author: Russo I
Year: 2019
Journal: Cereb Cortex
Title: p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits.
Volume: 29
Issue: 1
Pages: 91-105
Publication
First Author: Salamon I
Year: 2023
Journal: Nat Commun
Title: Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.
Volume: 14
Issue: 1
Pages: 6025
Publication
First Author: Munton RP
Year: 2007
Journal: Mol Cell Proteomics
Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.
Volume: 6
Issue: 2
Pages: 283-93
Publication
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 4
Pages: 167-80
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt