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Search results 1 to 100 out of 559 for Srebf1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: hamster, Chinese
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Toledo EM
Year: 2020
Journal: Cell Rep
Title: Srebf1 Controls Midbrain Dopaminergic Neurogenesis.
Volume: 31
Issue: 5
Pages: 107601
Gene
Type: gene
Organism: human
Publication  
First Author: Guix FX
Year: 2021
Journal: Life Sci Alliance
Title: Increased exosome secretion in neurons aging in vitro by NPC1-mediated endosomal cholesterol buildup.
Volume: 4
Issue: 8
Publication
First Author: Cedó L
Year: 2017
Journal: PLoS One
Title: Human hepatic lipase overexpression in mice induces hepatic steatosis and obesity through promoting hepatic lipogenesis and white adipose tissue lipolysis and fatty acid uptake.
Volume: 12
Issue: 12
Pages: e0189834
Publication  
First Author: Horie T
Year: 2014
Journal: Sci Rep
Title: MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo.
Volume: 4
Pages: 5312
Publication
First Author: Nishino T
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: SREBF1/MicroRNA-33b Axis Exhibits Potent Effect on Unstable Atherosclerotic Plaque Formation In Vivo.
Volume: 38
Issue: 10
Pages: 2460-2473
Publication
First Author: Takeuchi Y
Year: 2016
Journal: Cell Rep
Title: KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.
Volume: 16
Issue: 9
Pages: 2373-86
Publication
First Author: Araki M
Year: 2022
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatocyte- or macrophage-specific SREBP-1a deficiency in mice exacerbates methionine- and choline-deficient diet-induced nonalcoholic fatty liver disease.
Volume: 323
Issue: 6
Pages: G627-G639
Publication
First Author: Im SS
Year: 2009
Journal: Mol Cell Biol
Title: Sterol regulatory element binding protein 1a regulates hepatic fatty acid partitioning by activating acetyl coenzyme A carboxylase 2.
Volume: 29
Issue: 17
Pages: 4864-72
Publication
First Author: Rudolph MC
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: Sterol regulatory element binding protein and dietary lipid regulation of fatty acid synthesis in the mammary epithelium.
Volume: 299
Issue: 6
Pages: E918-27
Publication
First Author: Vergnes L
Year: 2016
Journal: J Lipid Res
Title: SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression.
Volume: 57
Issue: 3
Pages: 410-21
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Matsuzaka T
Year: 2002
Journal: J Lipid Res
Title: Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha.
Volume: 43
Issue: 1
Pages: 107-14
Publication
First Author: Inoue J
Year: 1999
Journal: Biosci Biotechnol Biochem
Title: A novel splicing isoform of mouse sterol regulatory element-binding protein-1 (SREBP-1).
Volume: 63
Issue: 1
Pages: 243-5
Publication
First Author: Shimano H
Year: 1997
Journal: J Clin Invest
Title: Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.
Volume: 99
Issue: 5
Pages: 846-54
Publication
First Author: Liang G
Year: 2002
Journal: J Biol Chem
Title: Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c.
Volume: 277
Issue: 11
Pages: 9520-8
Publication
First Author: Horton JD
Year: 2003
Journal: J Biol Chem
Title: Overexpression of sterol regulatory element-binding protein-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver.
Volume: 278
Issue: 38
Pages: 36652-60
Publication
First Author: Im SS
Year: 2011
Journal: Cell Metab
Title: Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a.
Volume: 13
Issue: 5
Pages: 540-9
Publication
First Author: Nakakuki M
Year: 2007
Journal: FEBS J
Title: A transcription factor of lipid synthesis, sterol regulatory element-binding protein (SREBP)-1a causes G(1) cell-cycle arrest after accumulation of cyclin-dependent kinase (cdk) inhibitors.
Volume: 274
Issue: 17
Pages: 4440-52
Publication
First Author: Lerat H
Year: 2009
Journal: J Biol Chem
Title: Hepatitis C virus proteins induce lipogenesis and defective triglyceride secretion in transgenic mice.
Volume: 284
Issue: 48
Pages: 33466-74
Publication  
First Author: Horie T
Year: 2013
Journal: Nat Commun
Title: MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice.
Volume: 4
Pages: 2883
Publication
First Author: Herrera E
Year: 1999
Journal: EMBO J
Title: Telomere shortening in mTR-/- embryos is associated with failure to close the neural tube.
Volume: 18
Issue: 5
Pages: 1172-81
Publication
First Author: Diraison F
Year: 2008
Journal: J Lipid Res
Title: SREBP1 is required for the induction by glucose of pancreatic beta-cell genes involved in glucose sensing.
Volume: 49
Issue: 4
Pages: 814-22
Publication
First Author: Cermenati G
Year: 2015
Journal: Cell Metab
Title: Lack of sterol regulatory element binding factor-1c imposes glial Fatty Acid utilization leading to peripheral neuropathy.
Volume: 21
Issue: 4
Pages: 571-83
Publication
First Author: Ishigaki N
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Involvement of glomerular SREBP-1c in diabetic nephropathy.
Volume: 364
Issue: 3
Pages: 502-8
Publication      
First Author: Lee JH
Year: 2017
Journal: Mol Cell Biol
Title: RNF20 Suppresses Tumorigenesis by Inhibiting SREBP1c-PTTG1 Axis in Kidney Cancer.
Publication
First Author: Park HJ
Year: 2008
Journal: J Clin Invest
Title: Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP.
Volume: 118
Issue: 1
Pages: 259-71
Publication
First Author: Lee G
Year: 2022
Journal: Cell Metab
Title: SREBP1c-PARP1 axis tunes anti-senescence activity of adipocytes and ameliorates metabolic imbalance in obesity.
Volume: 34
Issue: 5
Pages: 702-718.e5
Publication
First Author: Mitro N
Year: 2017
Journal: J Neurochem
Title: Sterol regulatory element binding protein-1C knockout mice show altered neuroactive steroid levels in sciatic nerve.
Volume: 142
Issue: 3
Pages: 420-428
Publication
First Author: Fujii N
Year: 2017
Journal: Aging Cell
Title: Sterol regulatory element-binding protein-1c orchestrates metabolic remodeling of white adipose tissue by caloric restriction.
Volume: 16
Issue: 3
Pages: 508-517
Publication
First Author: Song Y
Year: 2015
Journal: J Hepatol
Title: Thyroid-stimulating hormone regulates hepatic bile acid homeostasis via SREBP-2/HNF-4α/CYP7A1 axis.
Volume: 62
Issue: 5
Pages: 1171-9
Publication  
First Author: Ang MJ
Year: 2021
Journal: Int J Mol Sci
Title: SREBP-1c Deficiency Affects Hippocampal Micromorphometry and Hippocampus-Dependent Memory Ability in Mice.
Volume: 22
Issue: 11
Publication
First Author: Nguyen TTP
Year: 2021
Journal: Mol Cell
Title: SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice.
Volume: 81
Issue: 18
Pages: 3820-3832.e7
Publication
First Author: Lee S
Year: 2019
Journal: Genes Brain Behav
Title: Deficiency of sterol regulatory element-binding protein-1c induces schizophrenia-like behavior in mice.
Volume: 18
Issue: 4
Pages: e12540
Publication
First Author: Hegarty BD
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c.
Volume: 102
Issue: 3
Pages: 791-6
Publication
First Author: Pravenec M
Year: 2001
Journal: Mamm Genome
Title: Identification of a mutation in ADD1/SREBP-1 in the spontaneously hypertensive rat.
Volume: 12
Issue: 4
Pages: 295-8
Publication
First Author: Yahagi N
Year: 1999
Journal: J Biol Chem
Title: A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids.
Volume: 274
Issue: 50
Pages: 35840-4
Publication
First Author: Flier JS
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: ADD-1 provides major new insight into the mechanism of insulin action.
Volume: 96
Issue: 25
Pages: 14191-2
Publication
First Author: Rho HK
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Transcriptional regulation of mouse 6-phosphogluconate dehydrogenase by ADD1/SREBP1c.
Volume: 332
Issue: 1
Pages: 288-96
Publication
First Author: Iwasaki Y
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Nuclear SREBP-1a causes loss of pancreatic beta-cells and impaired insulin secretion.
Volume: 378
Issue: 3
Pages: 545-50
Publication
First Author: Seo YK
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Genome-wide analysis of SREBP-1 binding in mouse liver chromatin reveals a preference for promoter proximal binding to a new motif.
Volume: 106
Issue: 33
Pages: 13765-9
Publication
First Author: Kotzka J
Year: 2012
Journal: PLoS One
Title: Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity.
Volume: 7
Issue: 2
Pages: e32609
Publication
First Author: Jideonwo V
Year: 2018
Journal: PLoS One
Title: Impact of silencing hepatic SREBP-1 on insulin signaling.
Volume: 13
Issue: 5
Pages: e0196704
Publication
First Author: Ma M
Year: 2020
Journal: J Lipid Res
Title: The lncRNA Gm15622 stimulates SREBP-1c expression and hepatic lipid accumulation by sponging the miR-742-3p in mice.
Volume: 61
Issue: 7
Pages: 1052-1064
GXD Expression    
Probe: MGI:7507531
Assay Type: RT-PCR
Annotation Date: 2023-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:7507565
Age: postnatal day 13
Image: 9
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7507531
Assay Type: RT-PCR
Annotation Date: 2023-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:7507565
Age: postnatal day 13
Image: 9
Specimen Label: KO
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3816117
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816921
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3816117
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816921
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3816117
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816921
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3816117
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816921
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3816117
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816921
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6111790
Assay Type: RT-PCR
Annotation Date: 2018-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6111876
Age: postnatal
Image: 5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6111790
Assay Type: RT-PCR
Annotation Date: 2018-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6111876
Age: postnatal
Image: 5
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6111791
Assay Type: RT-PCR
Annotation Date: 2018-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6111877
Age: postnatal
Image: 5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6111791
Assay Type: RT-PCR
Annotation Date: 2018-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6111877
Age: postnatal
Image: 5
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3816117
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816921
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3816117
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816921
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3055184
Assay Type: Northern blot
Annotation Date: 2004-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3531628
Stage: TS28
Assay Id: MGI:3055396
Age: postnatal week 4
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3055184
Assay Type: Northern blot
Annotation Date: 2004-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3531628
Stage: TS28
Assay Id: MGI:3055396
Age: postnatal week 4
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3055184
Assay Type: Northern blot
Annotation Date: 2004-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3531628
Stage: TS28
Assay Id: MGI:3055396
Age: postnatal week 4
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3816117
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816921
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3055184
Assay Type: Northern blot
Annotation Date: 2004-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3592628
Stage: TS28
Assay Id: MGI:3055396
Age: postnatal week 4
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3055184
Assay Type: Northern blot
Annotation Date: 2004-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3592628
Stage: TS28
Assay Id: MGI:3055396
Age: postnatal week 4
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3055184
Assay Type: Northern blot
Annotation Date: 2004-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3592628
Stage: TS28
Assay Id: MGI:3055396
Age: postnatal week 4
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6509670
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510252
Age: postnatal month 2
Image: 7
Specimen Label: WT 2MO
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6509670
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510252
Age: postnatal month 2
Image: 7
Specimen Label: DKO 2 MO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6509670
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510252
Age: postnatal month 7
Image: 7
Specimen Label: WT 7MO
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6509670
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510252
Age: postnatal month 7
Image: 7
Specimen Label: DKO 7MO
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4416355
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1870523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828437
Age: embryonic day 14.5
Image: euxassay_012074_09
Specimen Label: euxassay_012074_09
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4416355
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1870523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828437
Age: embryonic day 14.5
Image: euxassay_012074_10
Specimen Label: euxassay_012074_10
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3724696
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5421355
Age: embryonic day 14.5
Specimen Label: MH946; Specimen C1413
Detected: false
Specimen Num: 1