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Search results 1 to 100 out of 933 for Srf

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
6722 | SRF
Type: gene
Organism: human
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Gene
612861 | SRF
Type: gene
Organism: dog, domestic
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Gene
533039 | SRF
Type: gene
Organism: cattle
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Gene
396103 | SRF
Type: gene
Organism: chicken
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Gene
698861 | SRF
Type: gene
Organism: macaque, rhesus
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Gene
100497353 | srf
Type: gene
Organism: frog, western clawed
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Gene
501099 | Srf
Type: gene
Organism: rat
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Gene
462709 | SRF
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:106658 | Srf
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450728
Age: embryonic day 12.5
Image: Srf - E12.5
Note: There is moderate staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Srf - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450728
Age: embryonic day 14.5
Image: Srf - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Srf - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450728
Age: embryonic day 12.5
Image: Srf - E12.5
Note: There is moderate staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Srf - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450728
Age: embryonic day 14.5
Image: Srf - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Srf - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450728
Age: embryonic day 16.5
Image: Srf - E16.5
Note: There is strong staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Srf - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450728
Age: embryonic day 12.5
Image: Srf - E12.5
Note: There is moderate staining in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Srf - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450728
Age: embryonic day 14.5
Image: Srf - E14.5
Note: There is strong staining in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Srf - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450728
Age: embryonic day 12.5
Image: Srf - E12.5
Note: There is moderate staining in the mantle zone of the dorsal and ventral POAs, the PVH nucleus, the AVH and anterior and posterior IDs. Staining is either absent or ubiquitous in the mantle zone of the VMH and ARH nuclei.
Specimen Label: Srf - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450728
Age: embryonic day 14.5
Image: Srf - E14.5
Note: There is weak staining in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Srf - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450728
Age: embryonic day 16.5
Image: Srf - E16.5
Note: There is moderate staining in the mantle zone of the VMH nucleus and weak staining in the dorsal and ventral POAs, the PVH, SCH, DMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Label: Srf - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6444153
Assay Type: RNA in situ
Annotation Date: 2020-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3596115
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6444165
Age: embryonic day 9.5
Image: 1B Srf flex1/+; T(s)::Cre
Specimen Label: 1B Srf flex1/+; T(s)::Cre
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6444153
Assay Type: RNA in situ
Annotation Date: 2020-07-22
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3596115
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:6444165
Age: embryonic day 9.5
Image: 1B Srf flex1/flex1; T(s)::Cre
Note: Expression reduced in all mesodermal derived tissues. Expression not detectable in posterior mesodermal tissues.
Specimen Label: 1B Srf flex1/flex1; T(s)::Cre
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450728
Age: embryonic day 12.5
Image: Srf - E12.5
Note: There is moderate staining in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Label: Srf - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271822
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450728
Age: embryonic day 14.5
Image: Srf - E14.5
Note: There is weak staining in the mantle zone of the mam zone. Staining is either absent or ubiquitous in the mantle zone of the premam and supramam zones and the TT.
Specimen Label: Srf - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450728
Age: embryonic day 16.5
Image: Srf - E16.5
Note: There is weak staining in the mantle zone of the premam, mam and supramam zones.
Specimen Label: Srf - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450728
Age: embryonic day 12.5
Image: Srf - E12.5
Note: There is moderate staining in the ventricular zone of the dorsal and ventral POAs, the PVH nucleus, the AVH and anterior and posterior IDs. Staining is either absent or ubiquitous in the ventricular zone of the VMH and ARH nuclei.
Specimen Label: Srf - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450728
Age: embryonic day 14.5
Image: Srf - E14.5
Note: There is weak staining in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Srf - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450728
Age: embryonic day 16.5
Image: Srf - E16.5
Note: There is weak staining in the ventricular zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Label: Srf - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450728
Age: embryonic day 12.5
Image: Srf - E12.5
Note: There is moderate staining in the ventricular zone of the cerebral cortex.
Specimen Label: Srf - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450728
Age: embryonic day 14.5
Image: Srf - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Srf - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450728
Age: embryonic day 16.5
Image: Srf - E16.5
Note: There is weak staining in the ventricular zone of the cerebral cortex.
Specimen Label: Srf - E16.5
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450728
Age: embryonic day 12.5
Image: Srf - E12.5
Note: There is moderate staining in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Srf - E12.5
Detected: true
Specimen Num: 2
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•
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•
GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271022
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450728
Age: embryonic day 14.5
Image: Srf - E14.5
Note: There is weak staining in the ventricular zone of the mam zone. Staining is either absent or ubiquitous in the ventricular zone of the premam and supramam zones and the TT.
Specimen Label: Srf - E14.5
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450728
Age: embryonic day 16.5
Image: Srf - E16.5
Note: There is weak staining in the ventricular zone of the premam, mam and supramam zones.
Specimen Label: Srf - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450728
Age: embryonic day 12.5
Image: Srf - E12.5
Note: There is moderate staining in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Srf - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450728
Age: embryonic day 14.5
Image: Srf - E14.5
Note: There is weak staining in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Srf - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450728
Age: embryonic day 16.5
Image: Srf - E16.5
Note: There is weak staining in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Srf - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450728
Age: embryonic day 14.5
Image: Srf - E14.5
Note: There is weak staining in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Srf - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450728
Age: embryonic day 16.5
Image: Srf - E16.5
Note: There is weak staining in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Srf - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450728
Age: embryonic day 16.5
Image: Srf - E16.5
Note: There is strong staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Srf - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450728
Age: embryonic day 16.5
Image: Srf - E16.5
Note: There is weak staining in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Srf - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450728
Age: embryonic day 12.5
Image: Srf - E12.5
Note: There is moderate staining in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Srf - E12.5
Detected: true
Specimen Num: 2
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Publication
34389686 | J:313812
 
First Author: Betts CA
Year: 2021
Journal: Life Sci Alliance
Title: Dystrophin involvement in peripheral circadian SRF signalling.
Volume: 4
Issue: 10
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Publication
28125644 | J:246750
First Author: Rosenwald M
Year: 2017
Journal: PLoS One
Title: SRF and MKL1 Independently Inhibit Brown Adipogenesis.
Volume: 12
Issue: 1
Pages: e0170643
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Publication
23674601 | J:198683
First Author: Franco CA
Year: 2013
Journal: Development
Title: SRF selectively controls tip cell invasive behavior in angiogenesis.
Volume: 140
Issue: 11
Pages: 2321-33
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Publication
20709909 | J:166639
First Author: Ragu C
Year: 2010
Journal: Blood
Title: The transcription factor Srf regulates hematopoietic stem cell adhesion.
Volume: 116
Issue: 22
Pages: 4464-73
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Publication
12732141 | J:265732
First Author: Miralles F
Year: 2003
Journal: Cell
Title: Actin dynamics control SRF activity by regulation of its coactivator MAL.
Volume: 113
Issue: 3
Pages: 329-42
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Publication
29643333 | J:265721
First Author: Ikeda T
Year: 2018
Journal: Nat Commun
Title: Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs.
Volume: 9
Issue: 1
Pages: 1387
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Protein
Q9JM73
Organism: Mus musculus/domesticus
Length: 504  
Fragment?: false
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Publication
24574460 | J:210744
First Author: Taylor A
Year: 2014
Journal: Blood
Title: SRF is required for neutrophil migration in response to inflammation.
Volume: 123
Issue: 19
Pages: 3027-36
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Publication
30850733 | J:286136
First Author: Del Blanco B
Year: 2019
Journal: Cell Death Differ
Title: CBP and SRF co-regulate dendritic growth and synaptic maturation.
Volume: 26
Issue: 11
Pages: 2208-2222
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Publication
25636686 | J:319101
First Author: Kuzniewska B
Year: 2016
Journal: Mol Neurobiol
Title: Adult Deletion of SRF Increases Epileptogenesis and Decreases Activity-Induced Gene Expression.
Volume: 53
Issue: 3
Pages: 1478-1493
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Publication
29269426 | J:258240
First Author: Randrianarison-Huetz V
Year: 2018
Journal: J Cell Biol
Title: Srf controls satellite cell fusion through the maintenance of actin architecture.
Volume: 217
Issue: 2
Pages: 685-700
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Publication
15057274 | J:90120
First Author: Schratt G
Year: 2004
Journal: EMBO J
Title: SRF regulates Bcl-2 expression and promotes cell survival during murine embryonic development.
Volume: 23
Issue: 8
Pages: 1834-44
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Publication
35862101 | J:340092
First Author: Orlich MM
Year: 2022
Journal: Circ Res
Title: Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow.
Volume: 131
Issue: 4
Pages: 308-327
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Publication
15880109 | J:99232
First Author: Ramanan N
Year: 2005
Journal: Nat Neurosci
Title: SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability.
Volume: 8
Issue: 6
Pages: 759-67
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Publication
23558171 | J:265603
First Author: Baarlink C
Year: 2013
Journal: Science
Title: Nuclear actin network assembly by formins regulates the SRF coactivator MAL.
Volume: 340
Issue: 6134
Pages: 864-7
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Publication
28286024 | J:251882
First Author: Esnault C
Year: 2017
Journal: Mol Cell
Title: ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription.
Volume: 65
Issue: 6
Pages: 1081-1095.e5
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Publication
37982489 | J:345149
   
First Author: Zhou LY
Year: 2023
Journal: Elife
Title: Differential regulation of hair cell actin cytoskeleton mediated by SRF and MRTFB.
Volume: 12
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Publication
32210317 | J:286859
First Author: Wanner R
Year: 2020
Journal: Sci Rep
Title: Interference with SRF expression in skeletal muscles reduces peripheral nerve regeneration in mice.
Volume: 10
Issue: 1
Pages: 5281
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Publication
33441399 | J:320474
 
First Author: Jain M
Year: 2021
Journal: eNeuro
Title: SRF Is Required for Maintenance of Astrocytes in Non-Reactive State in the Mammalian Brain.
Volume: 8
Issue: 1
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Publication
24623780 | J:209602
First Author: Li CL
Year: 2014
Journal: J Neurosci
Title: SRF phosphorylation by glycogen synthase kinase-3 promotes axon growth in hippocampal neurons.
Volume: 34
Issue: 11
Pages: 4027-42
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GXD Expression
GXD Expression
   
Probe: MGI:6444157
Assay Type: RT-PCR
Annotation Date: 2020-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603914
Stage: TS14
Assay Id: MGI:6444169
Age: embryonic day 8.75-9.0
Image: 4
Specimen Label: Srf flex1/flex1; T(s)::Cre
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450728
Age: embryonic day 11.5
Note: There is strong staining in the ventricular zone of the cerebral cortex and the ganglionic eminences.
Specimen Label: Srf - E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450728
Age: embryonic day 11.5
Note: There is strong staining in the ventricular zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
Specimen Label: Srf - E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450728
Age: embryonic day 11.5
Note: There is strong staining in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
Specimen Label: Srf - E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442774
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450728
Age: embryonic day 11.5
Note: There is strong staining in the mantle zone of the dorsal thalamus, prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
Specimen Label: Srf - E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
18054567 | J:135616
First Author: Mericskay M
Year: 2007
Journal: Gastroenterology
Title: Inducible mouse model of chronic intestinal pseudo-obstruction by smooth muscle-specific inactivation of the SRF gene.
Volume: 133
Issue: 6
Pages: 1960-70
•
•
•
•
•
Publication
18054566 | J:135617
First Author: Angstenberger M
Year: 2007
Journal: Gastroenterology
Title: Severe intestinal obstruction on induced smooth muscle-specific ablation of the transcription factor SRF in adult mice.
Volume: 133
Issue: 6
Pages: 1948-59
•
•
•
•
•
Publication
21393865 | J:172010
First Author: Jin W
Year: 2011
Journal: J Clin Invest
Title: Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistance.
Volume: 121
Issue: 3
Pages: 918-29
•
•
•
•
•
Publication
16260633 | J:135043
First Author: Parlakian A
Year: 2005
Journal: Circulation
Title: Temporally controlled onset of dilated cardiomyopathy through disruption of the SRF gene in adult heart.
Volume: 112
Issue: 19
Pages: 2930-9
•
•
•
•
•
Publication
25453829 | J:315863
First Author: Vasudevan HN
Year: 2014
Journal: Dev Cell
Title: SRF regulates craniofacial development through selective recruitment of MRTF cofactors by PDGF signaling.
Volume: 31
Issue: 3
Pages: 332-344
•
•
•
•
•
Publication
33637797 | J:303820
First Author: Kepser LJ
Year: 2021
Journal: Sci Rep
Title: Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts.
Volume: 11
Issue: 1
Pages: 4789
•
•
•
•
•
Publication
20694003 | J:165284
First Author: Smith-Hicks C
Year: 2010
Journal: Nat Neurosci
Title: SRF binding to SRE 6.9 in the Arc promoter is essential for LTD in cultured Purkinje cells.
Volume: 13
Issue: 9
Pages: 1082-9
•
•
•
•
•
Publication
28716058 | J:287513
First Author: Lösing P
Year: 2017
Journal: Mol Brain
Title: SRF modulates seizure occurrence, activity induced gene transcription and hippocampal circuit reorganization in the mouse pilocarpine epilepsy model.
Volume: 10
Issue: 1
Pages: 30
•
•
•
•
•
Publication
25020278 | J:253683
 
First Author: Schwartz B
Year: 2014
Journal: Mech Dev
Title: SRF is essential for mesodermal cell migration during elongation of the embryonic body axis.
Volume: 133
Pages: 23-35
•
•
•
•
•
Publication
35918150 | J:330505
     
First Author: Drake KA
Year: 2022
Journal: J Am Soc Nephrol
Title: Transcription Factors YAP/TAZ and SRF Cooperate To Specify Renal Myofibroblasts in the Developing Mouse Kidney.
•
•
•
•
•
Publication
29284006 | J:255578
First Author: Dai X
Year: 2017
Journal: PLoS One
Title: SM22α suppresses cytokine-induced inflammation and the transcription of NF-κB inducing kinase (Nik) by modulating SRF transcriptional activity in vascular smooth muscle cells.
Volume: 12
Issue: 12
Pages: e0190191
•
•
•
•
•
Publication
38014633 | J:343799
 
First Author: Katano W
Year: 2023
Journal: Development
Title: Sall1 and Sall4 cooperatively interact with Myocd and SRF to promote cardiomyocyte proliferation by regulating CDK and cyclin genes.
Volume: 150
Issue: 24
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184238
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191386
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Srf
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184238
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191386
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Srf
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184238
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191386
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Srf
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6184238
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191386
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Srf
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184238
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191386
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Srf
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184238
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191386
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Srf
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6184238
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191386
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Srf
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6444155
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609614
Pattern: Regionally restricted
Stage: TS14
Assay Id: MGI:6444167
Age: embryonic day 9.0
Image: 2A E-cadherin Srf flex1/+; T(s)::Cre
Specimen Label: 2A E-cadherin Srf flex1/+; T(s)::Cre
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6444155
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609614
Pattern: Regionally restricted
Stage: TS14
Assay Id: MGI:6444167
Age: embryonic day 9.0
Image: 2A E-cadherin Srf flex1/flex1; T(s)::Cre
Note: Expression in epithelium surrounding mesoderm.
Specimen Label: 2A E-cadherin Srf flex1/flex1; T(s)::Cre
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6444156
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609614
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:6444168
Age: embryonic day 9.0
Image: 2A Vimentin Srf flex1/flex1; T(s)::Cre
Specimen Label: 2A Vimentin Srf flex1/flex1; T(s)::Cre
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6444154
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607114
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:6444166
Age: embryonic day 9.0
Image: 2A Brachyury Srf flex1/+; T(s)::Cre
Specimen Label: 2A Brachyury Srf flex1/+; T(s)::Cre
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6444154
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607114
Pattern: Regionally restricted
Stage: TS14
Assay Id: MGI:6444166
Age: embryonic day 9.0
Image: 2A Brachyury Srf flex1/flex1; T(s)::Cre
Note: Authors report a significant number of expressing cells in caudal end of embryo.
Specimen Label: 2A Brachyury Srf flex1/flex1; T(s)::Cre
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6444155
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1607114
Stage: TS14
Assay Id: MGI:6444167
Age: embryonic day 9.0
Image: 2A E-cadherin Srf flex1/flex1; T(s)::Cre
Note: No expression in mesodermal cells at caudal end of embryo.
Specimen Label: 2A E-cadherin Srf flex1/flex1; T(s)::Cre
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6444156
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607114
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:6444168
Age: embryonic day 9.0
Image: 2A Vimentin Srf flex1/+; T(s)::Cre
Specimen Label: 2A Vimentin Srf flex1/+; T(s)::Cre
Detected: true
Specimen Num: 1
•
•
•
•
•
Author
Twigg SRF
•
•
•
•
•
Publication
21552476 | J:172655
 
First Author: Sandström J
Year: 2011
Journal: Mol Vis
Title: Degeneration of the mouse retina upon dysregulated activity of serum response factor.
Volume: 17
Pages: 1110-27
•
•
•
•
•
Publication
30771308 | J:276074
 
First Author: Quijada P
Year: 2019
Journal: J Mol Cell Cardiol
Title: Pre-existing fibroblasts of epicardial origin are the primary source of pathological fibrosis in cardiac ischemia and aging.
Volume: 129
Pages: 92-104
•
•
•
•
•
Publication
29114040 | J:293086
First Author: Guo B
Year: 2018
Journal: J Am Soc Nephrol
Title: Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.
Volume: 29
Issue: 2
Pages: 416-422
•
•
•
•
•
Publication
26221020 | J:226506
First Author: Weinl C
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Endothelial depletion of murine SRF/MRTF provokes intracerebral hemorrhagic stroke.
Volume: 112
Issue: 32
Pages: 9914-9
•
•
•
•
•
Publication
20534669 | J:161853
First Author: Mokalled MH
Year: 2010
Journal: Development
Title: Myocardin-related transcription factors regulate the Cdk5/Pctaire1 kinase cascade to control neurite outgrowth, neuronal migration and brain development.
Volume: 137
Issue: 14
Pages: 2365-74
•
•
•
•
•
Publication
33361330 | J:299963
 
First Author: Guo Y
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling.
Volume: 118
Issue: 2
•
•
•
•
•
Publication
23563308 | J:201346
First Author: Weinl C
Year: 2013
Journal: J Clin Invest
Title: Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae.
Volume: 123
Issue: 5
Pages: 2193-206
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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