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Search results 1 to 82 out of 82 for Srgap1

0.027s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
57522 | SRGAP1
Type: gene
Organism: human
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Gene
539452 | SRGAP1
Type: gene
Organism: cattle
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Gene
417821 | SRGAP1
Type: gene
Organism: chicken
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Gene
717169 | SRGAP1
Type: gene
Organism: macaque, rhesus
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Gene
100485190 | srgap1
Type: gene
Organism: frog, western clawed
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Gene
314903 | Srgap1
Type: gene
Organism: rat
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Gene
481144 | SRGAP1
Type: gene
Organism: dog, domestic
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Gene
452043 | SRGAP1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2152936 | Srgap1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
33514561 | J:333727
First Author: Rogg M
Year: 2021
Journal: J Am Soc Nephrol
Title: SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.
Volume: 32
Issue: 3
Pages: 563-579
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Publication
26026792 | J:226724
First Author: Hwang DY
Year: 2015
Journal: Hum Genet
Title: Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract.
Volume: 134
Issue: 8
Pages: 905-16
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Publication
19137586 | J:146175
First Author: Bacon C
Year: 2009
Journal: J Comp Neurol
Title: Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system.
Volume: 513
Issue: 2
Pages: 224-36
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Publication
11672528 | J:72329
First Author: Wong K
Year: 2001
Journal: Cell
Title: Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
Volume: 107
Issue: 2
Pages: 209-21
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Publication
27882344 | J:240644
First Author: Fan X
Year: 2016
Journal: JCI Insight
Title: SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion.
Volume: 1
Issue: 19
Pages: e86934
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Protein Coding Gene
MGP_CAROLIEiJ_G0015861 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017787 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017762 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017726 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017550 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2152936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018181 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017110 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017519 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017625 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017620 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017699 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017648 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018221 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016895 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017171 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031225 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016686 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
Probe: MGI:4424913
Assay Type: RNA in situ
Annotation Date: 2020-10-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2775622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6469728
Age: embryonic day 14.5
Image: 7
Note: Expression is seen in the podocytes.
Specimen Label: 7
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4882595
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1646928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4946066
Age: postnatal day 7
Image: S2G
Specimen Label: S2G
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4882595
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1646919
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4946066
Age: embryonic day 11.5
Image: S1F
Specimen Label: S1F
Detected: true
Specimen Num: 1
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Publication
21655271 | J:223910
First Author: Bacon C
Year: 2011
Journal: PLoS One
Title: Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.
Volume: 6
Issue: 5
Pages: e19887
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Publication
21931791 | J:177885
First Author: Brunskill EW
Year: 2011
Journal: PLoS One
Title: Defining the molecular character of the developing and adult kidney podocyte.
Volume: 6
Issue: 9
Pages: e24640
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
20944010 | J:165791
First Author: Ye BQ
Year: 2010
Journal: J Immunol
Title: Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation.
Volume: 185
Issue: 10
Pages: 6294-305
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Protein
Q91Z69
Organism: Mus musculus/domesticus
Length: 1062  
Fragment?: false
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Publication
16857672 | -
First Author: Li X
Year: 2006
Journal: J Biol Chem
Title: Structural basis of Robo proline-rich motif recognition by the srGAP1 Src homology 3 domain in the Slit-Robo signaling pathway.
Volume: 281
Issue: 38
Pages: 28430-7
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Publication
22467852 | -
First Author: Coutinho-Budd J
Year: 2012
Journal: J Cell Sci
Title: The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.
Volume: 125
Issue: Pt 14
Pages: 3390-401
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Publication
22159416 | -
First Author: Endris V
Year: 2011
Journal: J Cell Sci
Title: SrGAP3 interacts with lamellipodin at the cell membrane and regulates Rac-dependent cellular protrusions.
Volume: 124
Issue: Pt 23
Pages: 3941-55
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Protein Domain
IPR035648 | srGAP1/2/3_SH3
Type: Domain
Description: This entry represents the SH3 domain found in srGAP proteins 1, 2 and 3. srGAP1 (also called ARHGAP13) is a key GTPase activating protein (GAP) downstream of Slit-Robo pathway, and has been shown to inhibit neuronal migration and glioma cell invasion by reducing the activation of Cdc42 []. srGAP2 (ARHGAP34) regulates neuronal morphogenesis through the ability of its F-BAR domain to regulate membrane deformation and induce filopodia formation []. srGAP3 (ARHGAP14) interacts with lamellipodin at the cell membrane and regulates Rac-dependent cellular protrusions []. The SLIT-ROBO Rho GTPase-activating protein (srGAP) family consists of four members: srGAP1, -2, -3 and -4. They contain F-BAR, RhoGAP and SH3 domains. Their RhoGAP domain is involved in negative regulation of Rho GTPase activities important for cytoskeleton rearrangement []. The srGAP family members have an "inverse F-BAR"or IF-BAR domain that is distinct from other F-BAR domains such as FBP17. They are multifunctional adaptor proteins involved in various aspects of neuronal development [].
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Publication
32973238 | J:296236
First Author: Kandilya D
Year: 2020
Journal: Sci Rep
Title: High glucose alters the DNA methylation pattern of neurodevelopment associated genes in human neural progenitor cells in vitro.
Volume: 10
Issue: 1
Pages: 15676
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Publication
23505444 | -
First Author: Ma Y
Year: 2013
Journal: PLoS One
Title: The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells.
Volume: 8
Issue: 3
Pages: e57865
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Publication
20810653 | -
First Author: Guo S
Year: 2010
Journal: J Biol Chem
Title: srGAP2 arginine methylation regulates cell migration and cell spreading through promoting dimerization.
Volume: 285
Issue: 45
Pages: 35133-41
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Protein
A0A087WS73
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: true
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Protein
Q91Z68
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
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Protein
Q3TSN4
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
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Protein
A0A087WS59
Organism: Mus musculus/domesticus
Length: 451  
Fragment?: true
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Protein
A0A087WSQ1
Organism: Mus musculus/domesticus
Length: 649  
Fragment?: true
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Protein
Q91Z67
Organism: Mus musculus/domesticus
Length: 1071  
Fragment?: false
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Protein
Q812A2
Organism: Mus musculus/domesticus
Length: 1099  
Fragment?: false
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Protein
D3YZW1
Organism: Mus musculus/domesticus
Length: 1085  
Fragment?: false
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Protein
A0A087WNM1
Organism: Mus musculus/domesticus
Length: 858  
Fragment?: false
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Protein
E9QN14
Organism: Mus musculus/domesticus
Length: 1075  
Fragment?: false
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Protein
F8VPQ4
Organism: Mus musculus/domesticus
Length: 1099  
Fragment?: false
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Protein
A0A2X0SZ45
Organism: Mus musculus/domesticus
Length: 1106  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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