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Search results 1 to 100 out of 152 for Ssh1

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
54434 | SSH1
Type: gene
Organism: human
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Gene
100495893 | ssh1
Type: gene
Organism: frog, western clawed
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Gene
304580 | Ssh1
Type: gene
Organism: rat
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Gene
477526 | SSH1
Type: gene
Organism: dog, domestic
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Gene
467124 | SSH1
Type: gene
Organism: chimpanzee
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Gene
538233 | SSH1
Type: gene
Organism: cattle
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Gene
707809 | SSH1
Type: gene
Organism: macaque, rhesus
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Gene
101750781 | SSH1
Type: gene
Organism: chicken
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Protein Domain
IPR027233 | SSH1
Type: Family
Description: Slingshot homologue 1 (SSH1) is a protein phosphatase which regulates actin filament dynamics. It dephosphorylates and activates the actin binding/depolymerising factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly [, , ].
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Protein Coding Gene
MGI:2686240 | Ssh1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
14531860 | J:89966
First Author: Ohta Y
Year: 2003
Journal: Genes Cells
Title: Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin.
Volume: 8
Issue: 10
Pages: 811-24
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Publication
33044112 | J:313635
First Author: Fang C
Year: 2021
Journal: Autophagy
Title: SSH1 impedes SQSTM1/p62 flux and MAPT/Tau clearance independent of CFL (cofilin) activation.
Volume: 17
Issue: 9
Pages: 2144-2165
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Publication
15660133 | -
First Author: Soosairajah J
Year: 2005
Journal: EMBO J
Title: Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin.
Volume: 24
Issue: 3
Pages: 473-86
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Protein
Q76I79
Organism: Mus musculus/domesticus
Length: 1042  
Fragment?: false
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Protein
F8WHT2
Organism: Mus musculus/domesticus
Length: 999  
Fragment?: false
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Protein
F7CBJ9
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
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Publication
16230460 | -
First Author: Nishita M
Year: 2005
Journal: J Cell Biol
Title: Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration.
Volume: 171
Issue: 2
Pages: 349-59
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Publication
36092812 | J:328922
 
First Author: Cazzaro S
Year: 2022
Journal: Front Aging Neurosci
Title: Slingshot homolog-1 mediates the secretion of small extracellular vesicles containing misfolded proteins by regulating autophagy cargo receptors and actin dynamics.
Volume: 14
Pages: 933979
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Publication
30291325 | J:284923
First Author: Williams HC
Year: 2019
Journal: Lab Invest
Title: The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo.
Volume: 99
Issue: 3
Pages: 399-410
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Publication
17535256 | J:127110
First Author: Kurita S
Year: 2007
Journal: Genes Cells
Title: Actin filaments-stabilizing and -bundling activities of cofilin-phosphatase Slingshot-1.
Volume: 12
Issue: 5
Pages: 663-76
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Publication
37463212 | J:344394
First Author: Cazzaro S
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease.
Volume: 120
Issue: 30
Pages: e2217128120
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Protein Coding Gene
MGP_CAROLIEiJ_G0027585 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029927 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029892 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029830 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029903 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2686240 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030357 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029590 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029740 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029697 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029829 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030398 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028745 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029107 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024167 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028583 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:3804516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3804675
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3804516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3804675
Age: postnatal adult
Specimen Label: Thymus
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3804516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3804675
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3804516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3804675
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3804516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3804675
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3804516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3804675
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3804516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:3804675
Age: postnatal adult
Specimen Label: Small intestine
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3804516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3804675
Age: postnatal adult
Specimen Label: Skeletal Muscle
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3804516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804675
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:7645261
Assay Type: RNA in situ
Annotation Date: 2024-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3290322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7645269
Age: embryonic day 14.5
Image: 4D - Slingshot1
Note: Expression is localized in the growing apex of the epithelium.
Specimen Label: 4D - Slingshot1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3804681
Age: embryonic day 14.5
Specimen Label: 8H
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3804681
Age: embryonic day 14.5
Specimen Label: 8J
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3804681
Age: postnatal adult
Specimen Label: 8M
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3804681
Age: embryonic day 14.5
Specimen Label: 8H
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:3804681
Age: embryonic day 14.5
Specimen Label: 8A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1797222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3804681
Age: embryonic day 14.5
Note: Expression is in the testis tubes.
Specimen Label: 9F
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3804681
Age: embryonic day 14.5
Specimen Label: 8H
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3804681
Age: embryonic day 14.5
Specimen Label: 8H
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3804681
Age: postnatal adult
Specimen Label: 8M
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Spotted
Stage: TS22
Assay Id: MGI:3804681
Age: embryonic day 14.5
Note: Expression is more strongly in subsets of cells in the ventral horn of the spinal cord.
Specimen Label: 8E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3804681
Age: postnatal adult
Specimen Label: 8N
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:3804678
Assay Type: RNA in situ
Annotation Date: 2008-09-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3804681
Age: embryonic day 14.5
Note: Expression is in the outer neuroblastic layer and is strong in the inner neuroblastic layer.
Specimen Label: 8J
Detected: true
Specimen Num: 4
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Publication
24345679 | J:259563
First Author: Xiang SY
Year: 2013
Journal: Sci Signal
Title: PLCε, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart.
Volume: 6
Issue: 306
Pages: ra108
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Publication
19000834 | J:142802
First Author: Huang TY
Year: 2008
Journal: Dev Cell
Title: Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation.
Volume: 15
Issue: 5
Pages: 691-703
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Publication
27588418 | J:347204
First Author: Morita R
Year: 2016
Journal: PLoS One
Title: Coordination of Cellular Dynamics Contributes to Tooth Epithelium Deformations.
Volume: 11
Issue: 9
Pages: e0161336
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Publication
30228103 | J:266546
 
First Author: Brown JM
Year: 2018
Journal: Development
Title: Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics.
Volume: 145
Issue: 19
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Publication
26273529 | J:227247
 
First Author: Brommage R
Year: 2014
Journal: Bone Res
Title: High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.
Volume: 2
Pages: 14034
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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GO Term
GO:0071261 | Ssh1 translocon complex
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
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First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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