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Search results 1 to 75 out of 75 for Stap2

0.032s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
55620 | STAP2
Type: gene
Organism: human
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Gene
100485111 | stap2
Type: gene
Organism: frog, western clawed
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Gene
104003239 | STAP2
Type: gene
Organism: chimpanzee
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Gene
107055321 | STAP2
Type: gene
Organism: chicken
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Gene
363334 | Stap2
Type: gene
Organism: rat
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Gene
485041 | STAP2
Type: gene
Organism: dog, domestic
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Gene
505456 | STAP2
Type: gene
Organism: cattle
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Gene
718949 | STAP2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2147039 | Stap2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
28430604 | J:274845
First Author: Muraoka D
Year: 2017
Journal: Oncotarget
Title: Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation.
Volume: 8
Issue: 19
Pages: 30766-30780
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Publication
15611091 | J:97253
First Author: Sekine Y
Year: 2005
Journal: J Biol Chem
Title: Physical and functional interactions between STAP-2/BKS and STAT5.
Volume: 280
Issue: 9
Pages: 8188-96
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Protein Coding Gene
MGP_CAROLIEiJ_G0021758 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023906 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023866 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023835 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023867 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023630 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2147039 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024311 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023607 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023735 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024356 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022858 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023177 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020747 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022670 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
22611243 | J:188960
First Author: Sekine Y
Year: 2012
Journal: J Immunol
Title: Signal-transducing adaptor protein-2 modulates Fas-mediated T cell apoptosis by interacting with caspase-8.
Volume: 188
Issue: 12
Pages: 6194-204
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Publication
33388414 | J:310833
 
First Author: Saito H
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice.
Volume: 537
Pages: 118-124
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Publication
16365431 | J:126269
First Author: Sekine Y
Year: 2006
Journal: J Immunol
Title: Modulation of TLR4 signaling by a novel adaptor protein signal-transducing adaptor protein-2 in macrophages.
Volume: 176
Issue: 1
Pages: 380-9
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Publication
30726917 | J:276903
First Author: Kashiwakura JI
Year: 2019
Journal: Int Immunol
Title: STAP-2 positively regulates FcεRI-mediated basophil activation and basophil-dependent allergic inflammatory reactions.
Volume: 31
Issue: 5
Pages: 349-356
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Publication
24616480 | J:210230
First Author: Sekine Y
Year: 2014
Journal: J Immunol
Title: Signal-transducing adaptor protein-2 controls the IgE-mediated, mast cell-mediated anaphylactic responses.
Volume: 192
Issue: 8
Pages: 3488-95
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Publication
35725273 | J:344981
First Author: Saitoh K
Year: 2022
Journal: J Immunol
Title: STAP-2 Is a Novel Positive Regulator of TCR-Proximal Signals.
Volume: 209
Issue: 1
Pages: 57-68
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Publication
18573890 | J:139741
First Author: Ikeda O
Year: 2008
Journal: Mol Cell Biol
Title: STAP-2 negatively regulates both canonical and noncanonical NF-kappaB activation induced by Epstein-Barr virus-derived latent membrane protein 1.
Volume: 28
Issue: 16
Pages: 5027-42
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Publication
19933863 | J:157482
First Author: Sekine Y
Year: 2009
Journal: J Immunol
Title: Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells.
Volume: 183
Issue: 12
Pages: 7966-74
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Publication
17512498 | J:122454
First Author: Ikeda O
Year: 2007
Journal: Biochem Biophys Res Commun
Title: STAP-2 regulates c-Fms/M-CSF receptor signaling in murine macrophage Raw 264.7 cells.
Volume: 358
Issue: 3
Pages: 931-7
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Publication
12540842 | J:82584
First Author: Minoguchi M
Year: 2003
Journal: J Biol Chem
Title: STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif.
Volume: 278
Issue: 13
Pages: 11182-9
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Publication
17675501 | J:151218
First Author: Sekine Y
Year: 2007
Journal: J Immunol
Title: Signal-transducing adaptor protein-2 regulates integrin-mediated T cell adhesion through protein degradation of focal adhesion kinase.
Volume: 179
Issue: 4
Pages: 2397-407
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR039111 | STAP1/STAP2
Type: Family
Description: STAP1 and STAP2 are signal-transducing adaptor proteins. They contain Pleckstrin Homology (PH) and SH2 domains along with several tyrosine phosphorylation sites.STAP1 functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. It is phosphorylated by Tec and participates in a positive feedback loop, increasing Tec activity []. STAP-1 has been shown to interact with STAT5 []. STAP2 is a substrate of breast tumour kinase, an Src-type non-receptor tyrosine kinase that mediates the interactions linking proteins involved in signal transduction pathways [].
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Publication
21205088 | -
First Author: Ikeda O
Year: 2011
Journal: Cancer Sci
Title: Involvement of STAP-2 in Brk-mediated phosphorylation and activation of STAT5 in breast cancer cells.
Volume: 102
Issue: 4
Pages: 756-61
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Publication
24492713 | -
First Author: Sekine Y
Year: 2014
Journal: Biol Pharm Bull
Title: Adaptor protein STAP-2 modulates cellular signaling in immune systems.
Volume: 37
Issue: 2
Pages: 185-94
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Publication
20519854 | -
First Author: Sekine Y
Year: 2010
Journal: Yakugaku Zasshi
Title: [Novel adaptor protein, STAP-2 functions as a signal modulator in immune system].
Volume: 130
Issue: 6
Pages: 769-75
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Protein Domain
IPR035878 | STAP2_SH2
Type: Domain
Description: STAP2 belongs to the STAP family, whose members are adaptor proteins that play a crucial role in a variety of cellular signal transduction pathways by interacting with signaling or transcriptional molecules. It is composed of a Pleckstrin homology (PH) and a SH2 domain along with several tyrosine phosphorylation sites. It plays an important role in modulating both the innate and adaptive immune systems [, ]. It is a substrate of breast tumour kinase, an Src-type non-receptor tyrosine kinase that mediates the interactions linking proteins involved in signal transduction pathways [].This entry represents the SH2 domain of STAP2.
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Publication
10518561 | -
First Author: Ohya K
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinase.
Volume: 96
Issue: 21
Pages: 11976-81
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Protein
Q8R0L1
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
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Protein
B7ZP01
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein
A0A0H2UKC0
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein
Q9JM90
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
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