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Search results 1 to 74 out of 74 for Stap2

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
55620 | STAP2
Type: gene
Organism: human
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Gene
505456 | STAP2
Type: gene
Organism: cattle
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Gene
718949 | STAP2
Type: gene
Organism: macaque, rhesus
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Gene
100485111 | stap2
Type: gene
Organism: frog, western clawed
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Gene
104003239 | STAP2
Type: gene
Organism: chimpanzee
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Gene
107055321 | STAP2
Type: gene
Organism: chicken
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Gene
363334 | Stap2
Type: gene
Organism: rat
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Gene
485041 | STAP2
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:2147039 | Stap2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
28430604 | J:274845
First Author: Muraoka D
Year: 2017
Journal: Oncotarget
Title: Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation.
Volume: 8
Issue: 19
Pages: 30766-30780
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Publication
15611091 | J:97253
First Author: Sekine Y
Year: 2005
Journal: J Biol Chem
Title: Physical and functional interactions between STAP-2/BKS and STAT5.
Volume: 280
Issue: 9
Pages: 8188-96
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Protein Coding Gene
MGP_CAROLIEiJ_G0021758 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023906 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023866 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023835 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023867 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023630 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2147039 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024311 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023607 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023735 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024356 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022858 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023177 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020747 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022670 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16365431 | J:126269
First Author: Sekine Y
Year: 2006
Journal: J Immunol
Title: Modulation of TLR4 signaling by a novel adaptor protein signal-transducing adaptor protein-2 in macrophages.
Volume: 176
Issue: 1
Pages: 380-9
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Publication
33388414 | J:310833
 
First Author: Saito H
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Graft-versus-host disease develops in mice transplanted with lymphocyte-depleted bone marrow cells from signal-transducing adaptor protein-2 transgenic mice.
Volume: 537
Pages: 118-124
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Publication
22611243 | J:188960
First Author: Sekine Y
Year: 2012
Journal: J Immunol
Title: Signal-transducing adaptor protein-2 modulates Fas-mediated T cell apoptosis by interacting with caspase-8.
Volume: 188
Issue: 12
Pages: 6194-204
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Publication
35725273 | J:344981
First Author: Saitoh K
Year: 2022
Journal: J Immunol
Title: STAP-2 Is a Novel Positive Regulator of TCR-Proximal Signals.
Volume: 209
Issue: 1
Pages: 57-68
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Publication
24616480 | J:210230
First Author: Sekine Y
Year: 2014
Journal: J Immunol
Title: Signal-transducing adaptor protein-2 controls the IgE-mediated, mast cell-mediated anaphylactic responses.
Volume: 192
Issue: 8
Pages: 3488-95
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Publication
30726917 | J:276903
First Author: Kashiwakura JI
Year: 2019
Journal: Int Immunol
Title: STAP-2 positively regulates FcεRI-mediated basophil activation and basophil-dependent allergic inflammatory reactions.
Volume: 31
Issue: 5
Pages: 349-356
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Publication
18573890 | J:139741
First Author: Ikeda O
Year: 2008
Journal: Mol Cell Biol
Title: STAP-2 negatively regulates both canonical and noncanonical NF-kappaB activation induced by Epstein-Barr virus-derived latent membrane protein 1.
Volume: 28
Issue: 16
Pages: 5027-42
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Publication
19933863 | J:157482
First Author: Sekine Y
Year: 2009
Journal: J Immunol
Title: Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells.
Volume: 183
Issue: 12
Pages: 7966-74
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Publication
17512498 | J:122454
First Author: Ikeda O
Year: 2007
Journal: Biochem Biophys Res Commun
Title: STAP-2 regulates c-Fms/M-CSF receptor signaling in murine macrophage Raw 264.7 cells.
Volume: 358
Issue: 3
Pages: 931-7
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Publication
12540842 | J:82584
First Author: Minoguchi M
Year: 2003
Journal: J Biol Chem
Title: STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif.
Volume: 278
Issue: 13
Pages: 11182-9
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Publication
17675501 | J:151218
First Author: Sekine Y
Year: 2007
Journal: J Immunol
Title: Signal-transducing adaptor protein-2 regulates integrin-mediated T cell adhesion through protein degradation of focal adhesion kinase.
Volume: 179
Issue: 4
Pages: 2397-407
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Protein Domain
IPR039111 | STAP1/STAP2
Type: Family
Description: STAP1 and STAP2 are signal-transducing adaptor proteins. They contain Pleckstrin Homology (PH) and SH2 domains along with several tyrosine phosphorylation sites.STAP1 functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. It is phosphorylated by Tec and participates in a positive feedback loop, increasing Tec activity []. STAP-1 has been shown to interact with STAT5 []. STAP2 is a substrate of breast tumour kinase, an Src-type non-receptor tyrosine kinase that mediates the interactions linking proteins involved in signal transduction pathways [].
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Publication
21205088 | -
First Author: Ikeda O
Year: 2011
Journal: Cancer Sci
Title: Involvement of STAP-2 in Brk-mediated phosphorylation and activation of STAT5 in breast cancer cells.
Volume: 102
Issue: 4
Pages: 756-61
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Publication
24492713 | -
First Author: Sekine Y
Year: 2014
Journal: Biol Pharm Bull
Title: Adaptor protein STAP-2 modulates cellular signaling in immune systems.
Volume: 37
Issue: 2
Pages: 185-94
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Publication
20519854 | -
First Author: Sekine Y
Year: 2010
Journal: Yakugaku Zasshi
Title: [Novel adaptor protein, STAP-2 functions as a signal modulator in immune system].
Volume: 130
Issue: 6
Pages: 769-75
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Protein Domain
IPR035878 | STAP2_SH2
Type: Domain
Description: STAP2 belongs to the STAP family, whose members are adaptor proteins that play a crucial role in a variety of cellular signal transduction pathways by interacting with signaling or transcriptional molecules. It is composed of a Pleckstrin homology (PH) and a SH2 domain along with several tyrosine phosphorylation sites. It plays an important role in modulating both the innate and adaptive immune systems [, ]. It is a substrate of breast tumour kinase, an Src-type non-receptor tyrosine kinase that mediates the interactions linking proteins involved in signal transduction pathways [].This entry represents the SH2 domain of STAP2.
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Publication
10518561 | -
First Author: Ohya K
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinase.
Volume: 96
Issue: 21
Pages: 11976-81
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Protein
Q8R0L1
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
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Protein
B7ZP01
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein
A0A0H2UKC0
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein
Q9JM90
Organism: Mus musculus/domesticus
Length: 297  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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