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Search results 1 to 100 out of 1376 for Star

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
6770 | STAR
Type: gene
Organism: human
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Gene
746738 | STAR
Type: gene
Organism: chimpanzee
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Gene
395421 | STAR
Type: gene
Organism: chicken
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Gene
63999 | star
Type: gene
Organism: zebrafish
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Gene
699515 | STAR
Type: gene
Organism: macaque, rhesus
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Gene
100492318 | star
Type: gene
Organism: frog, western clawed
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Gene
25557 | Star
Type: gene
Organism: rat
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Gene
443122 | STAR
Type: gene
Organism: sheep
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Gene
396597 | STAR
Type: gene
Organism: pig, domestic
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Gene
281507 | STAR
Type: gene
Organism: cattle
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Gene
475588 | STAR
Type: gene
Organism: dog, domestic
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Strain
MGI:2671064 | STAR
Attribute String: strain family
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Protein Domain
IPR029866 | StAR
Type: Family
Description: Steroidogenic acute regulatory protein (StAR) facilitates the biosynthesis of steroid hormones by regulating the transfer of cholesterol from the outer to the inner mitochondrial membrane []. Mitochondrial fusion and ERK phosphorylation can direct StAR to the outer mitochondrial membrane to achieve a large number of steroid molecules per unit of StAR [, ].
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Protein Coding Gene
MGI:102760 | Star
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:7408516
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-19
Strength: Present
Sex: Male
Emaps: EMAPS:2965528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7408522
Age: postnatal day 35
Image: 5 STAR P35 pStar
Note: No difference in localization or level of expression compared to wild type
Specimen Label: 5 STAR P35 pStar
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:7408516
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-19
Strength: Present
Sex: Male
Emaps: EMAPS:2965521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7408522
Age: embryonic day 13.5
Image: 3 STAR E13.5 WT
Specimen Label: 3 STAR E13.5 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7408516
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-19
Strength: Present
Sex: Male
Emaps: EMAPS:2965521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7408522
Age: embryonic day 13.5
Image: 3 STAR E13.5 pStar
Note: No difference in localization or level of expression compared to wild type
Specimen Label: 3 STAR E13.5 pStar
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7408516
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-19
Strength: Present
Sex: Male
Emaps: EMAPS:2965526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7408522
Age: embryonic day 18.5
Image: 3 STAR E18.5 WT
Specimen Label: 3 STAR E18.5 WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7408516
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-19
Strength: Present
Sex: Male
Emaps: EMAPS:2965526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7408522
Age: embryonic day 18.5
Image: 3 STAR E18.5 pStar
Note: No difference in localization or level of expression compared to wild type
Specimen Label: 3 STAR E18.5 pStar
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7408516
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-19
Strength: Present
Sex: Male
Emaps: EMAPS:2965528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7408522
Age: postnatal day 35
Image: 5 STAR P35 WT
Specimen Label: 5 STAR P35 WT
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:7408516
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-19
Strength: Present
Sex: Male
Emaps: EMAPS:2965528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7408522
Age: postnatal day 90
Image: 5 STAR P90 WT
Specimen Label: 5 STAR P90 WT
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:7408516
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-19
Strength: Present
Sex: Male
Emaps: EMAPS:2965528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7408522
Age: postnatal day 90
Image: 5 STAR P90 pStar
Note: No difference in localization or level of expression compared to wild type
Specimen Label: 5 STAR P90 pStar
Detected: true
Specimen Num: 8
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Protein
P51557
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Publication
16141272 | J:213905
First Author: Star EN
Year: 2005
Journal: J Physiol
Title: Real-time imaging of Rab3a and Rab5a reveals differential roles in presynaptic function.
Volume: 569
Issue: Pt 1
Pages: 103-17
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Publication
24945345 | -
First Author: Duarte A
Year: 2014
Journal: PLoS One
Title: Mitochondrial fusion and ERK activity regulate steroidogenic acute regulatory protein localization in mitochondria.
Volume: 9
Issue: 6
Pages: e100387
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Publication
18197253 | -
First Author: Poderoso C
Year: 2008
Journal: PLoS One
Title: A mitochondrial kinase complex is essential to mediate an ERK1/2-dependent phosphorylation of a key regulatory protein in steroid biosynthesis.
Volume: 3
Issue: 1
Pages: e1443
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Protein
Q6P910
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: false
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Publication
25540920 | J:223653
 
First Author: Castillo AF
Year: 2015
Journal: Mol Cell Endocrinol
Title: The role of mitochondrial fusion and StAR phosphorylation in the regulation of StAR activity and steroidogenesis.
Volume: 408
Pages: 73-9
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Publication
23172916 | J:189955
First Author: Star EN
Year: 2012
Journal: Development
Title: Regulation of retinal interneuron subtype identity by the Iroquois homeobox gene Irx6.
Volume: 139
Issue: 24
Pages: 4644-55
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Protein
A0A1B0GSV6
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: true
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Publication
10694364 | J:61040
First Author: Stocco DM
Year: 2000
Journal: J Endocrinol
Title: The role of the StAR protein in steroidogenesis: challenges for the future.
Volume: 164
Issue: 3
Pages: 247-53
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Publication
9888583 | J:55588
First Author: Caron KM
Year: 1998
Journal: Endocr Res
Title: Targeted disruption of StAR provides novel insights into congenital adrenal hyperplasia.
Volume: 24
Issue: 3-4
Pages: 827-34
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Gene
108863620 | LOC108863620
Type: gene
Organism: human
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Publication
27270953 | J:254083
 
First Author: Dou YD
Year: 2016
Journal: Sci Rep
Title: STMN1 Promotes Progesterone Production Via StAR Up-regulation in Mouse Granulosa Cells.
Volume: 6
Pages: 26691
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Publication
30922932 | J:278438
 
First Author: Chen Y
Year: 2019
Journal: Mol Cell Endocrinol
Title: Absence of the long noncoding RNA H19 results in aberrant ovarian STAR and progesterone production.
Volume: 490
Pages: 15-20
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Publication
19007846 | J:146974
First Author: Poderoso C
Year: 2009
Journal: Mol Cell Endocrinol
Title: Hormonal activation of a kinase cascade localized at the mitochondria is required for StAR protein activity.
Volume: 300
Issue: 1-2
Pages: 37-42
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Publication
11374809 | J:167700
First Author: Kotula M
Year: 2001
Journal: Folia Histochem Cytobiol
Title: Immunofluorescent localization of the StAR protein in mitochondria of mouse Leydig cells in vitro.
Volume: 39
Issue: 2
Pages: 169-70
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Publication
24269887 | J:205189
First Author: Korytowski W
Year: 2014
Journal: FEBS Lett
Title: Macrophage mitochondrial damage from StAR transport of 7-hydroperoxycholesterol: implications for oxidative stress-impaired reverse cholesterol transport.
Volume: 588
Issue: 1
Pages: 65-70
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Publication
10976923 | J:64337
First Author: Hasegawa T
Year: 2000
Journal: Mol Endocrinol
Title: Developmental roles of the steroidogenic acute regulatory protein (StAR) as revealed by StAR knockout mice.
Volume: 14
Issue: 9
Pages: 1462-71
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Publication
10319323 | J:54476
First Author: Reinhart AJ
Year: 1999
Journal: Mol Endocrinol
Title: SF-1 (steroidogenic factor-1) and C/EBP beta (CCAAT/enhancer binding protein-beta) cooperate to regulate the murine StAR (steroidogenic acute regulatory) promoter.
Volume: 13
Issue: 5
Pages: 729-41
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Publication
25724481 | J:224166
 
First Author: Bahat A
Year: 2015
Journal: Mol Cell Endocrinol
Title: Transcriptional activation of LON Gene by a new form of mitochondrial stress: A role for the nuclear respiratory factor 2 in StAR overload response (SOR).
Volume: 408
Pages: 62-72
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Publication
36614200 | J:332518
 
First Author: Manna PR
Year: 2023
Journal: Int J Mol Sci
Title: Expression and Function of StAR in Cancerous and Non-Cancerous Human and Mouse Breast Tissues: New Insights into Diagnosis and Treatment of Hormone-Sensitive Breast Cancer.
Volume: 24
Issue: 1
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Publication
34286295 | J:324729
First Author: Crespo EL
Year: 2021
Journal: STAR Protoc
Title: Bioluminescent optogenetic (BL-OG) activation of neurons during mouse postnatal brain development.
Volume: 2
Issue: 3
Pages: 100667
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Publication
33554147 | J:303420
First Author: Yamanaka S
Year: 2021
Journal: STAR Protoc
Title: In vivo regeneration of neo-nephrons in rodents by renal progenitor cell transplantation.
Volume: 2
Issue: 1
Pages: 100314
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Gene
56910 | STARD7
Type: gene
Organism: human
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Gene
10948 | STARD3
Type: gene
Organism: human
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Gene
10809 | STARD10
Type: gene
Organism: human
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Gene
134429 | STARD4
Type: gene
Organism: human
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Gene
80765 | STARD5
Type: gene
Organism: human
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Gene
147323 | STARD6
Type: gene
Organism: human
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Gene
90627 | STARD13
Type: gene
Organism: human
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Gene
9754 | STARD8
Type: gene
Organism: human
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Gene
57519 | STARD9
Type: gene
Organism: human
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Publication
38070137 | J:346601
First Author: Amberg N
Year: 2024
Journal: STAR Protoc
Title: Protocol for sorting cells from mouse brains labeled with mosaic analysis with double markers by flow cytometry.
Volume: 5
Issue: 1
Pages: 102771
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Publication
34825221 | J:346491
First Author: Grosjean C
Year: 2021
Journal: STAR Protoc
Title: Isolation and enrichment of mouse splenic T cells for ex vivo and in vivo T cell receptor stimulation assays.
Volume: 2
Issue: 4
Pages: 100961
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Publication
34258596 | J:320550
First Author: Nyeng P
Year: 2021
Journal: STAR Protoc
Title: Flow cytometry detection of surface and intracellular antigens in pancreas from a single mouse embryo.
Volume: 2
Issue: 3
Pages: 100636
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Publication
35118431 | J:330831
First Author: Watanabe-Takano H
Year: 2022
Journal: STAR Protoc
Title: Protocol for whole-mount X-gal staining combined with tissue clearing in embryo and adult mouse using CUBIC.
Volume: 3
Issue: 1
Pages: 101127
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Publication
12011453 | J:76531
First Author: Romanowski MJ
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain.
Volume: 99
Issue: 10
Pages: 6949-54
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Publication
11111087 | J:66551
First Author: Christenson LK
Year: 2000
Journal: Biochim Biophys Acta
Title: Steroidogenic acute regulatory protein (StAR) and the intramitochondrial translocation of cholesterol.
Volume: 1529
Issue: 1-3
Pages: 175-87
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Publication
9015355 | J:37872
First Author: Lee HK
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Nucleotide sequence of rat steroidogenic acute regulatory protein complementary DNA.
Volume: 230
Issue: 3
Pages: 528-32
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Publication
18187601 | J:132999
First Author: Sasaki G
Year: 2008
Journal: Mol Endocrinol
Title: Complex role of the mitochondrial targeting signal in the function of steroidogenic acute regulatory protein revealed by bacterial artificial chromosome transgenesis in vivo.
Volume: 22
Issue: 4
Pages: 951-64
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Publication
24850413 | J:215241
First Author: Sasaki G
Year: 2014
Journal: Mol Endocrinol
Title: The contribution of serine 194 phosphorylation to steroidogenic acute regulatory protein function.
Volume: 28
Issue: 7
Pages: 1088-96
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Publication
7588386 | J:26658
First Author: Clark BJ
Year: 1995
Journal: Endocr Res
Title: Expression of the steroidogenic acute regulatory (StAR) protein: a novel LH-induced mitochondrial protein required for the acute regulation of steroidogenesis in mouse Leydig tumor cells.
Volume: 21
Issue: 1-2
Pages: 243-57
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Publication
9013761 | J:38302
First Author: Caron KM
Year: 1997
Journal: Mol Endocrinol
Title: Characterization of the promoter region of the mouse gene encoding the steroidogenic acute regulatory protein.
Volume: 11
Issue: 2
Pages: 138-47
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Publication
9048613 | J:39141
First Author: Pilon N
Year: 1997
Journal: Endocrinology
Title: Porcine and bovine steroidogenic acute regulatory protein (StAR) gene expression during gestation.
Volume: 138
Issue: 3
Pages: 1085-91
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Publication
10026215 | J:53257
First Author: Manna PR
Year: 1999
Journal: J Biol Chem
Title: Molecular mechanisms of thyroid hormone-stimulated steroidogenesis in mouse leydig tumor cells. Involvement of the steroidogenic acute regulatory (StAR) protein.
Volume: 274
Issue: 9
Pages: 5909-18
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Publication
10462417 | J:57649
First Author: Stocco DM
Year: 1999
Journal: Bioessays
Title: Steroidogenic acute regulatory (StAR) protein: what's new?
Volume: 21
Issue: 9
Pages: 768-75
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Publication
30576426 | J:270006
First Author: Mizuno Y
Year: 2019
Journal: Endocrinology
Title: In Vivo Verification of the Pathophysiology of Lipoid Congenital Adrenal Hyperplasia in the Adrenal Cortex.
Volume: 160
Issue: 2
Pages: 331-338
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Publication
28611112 | J:319258
First Author: Geng XJ
Year: 2017
Journal: Reproduction
Title: MicroRNA-150 regulates steroidogenesis of mouse testicular Leydig cells by targeting STAR.
Volume: 154
Issue: 3
Pages: 229-236
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Publication
7961770 | J:21385
First Author: Clark BJ
Year: 1994
Journal: J Biol Chem
Title: The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR).
Volume: 269
Issue: 45
Pages: 28314-22
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Publication
8961254 | J:36881
First Author: Selvaraj N
Year: 1996
Journal: Mol Cell Endocrinol
Title: Partial sequencing of the rat steroidogenic acute regulatory protein message from immortalized granulosa cells: regulation by gonadotropins and isoproterenol.
Volume: 123
Issue: 2
Pages: 171-7
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Publication
35108514 | J:321590
First Author: Ramírez S
Year: 2022
Journal: Cell Metab
Title: Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders.
Volume: 34
Issue: 2
Pages: 269-284.e9
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Publication
19179481 | J:233578
First Author: Duan H
Year: 2009
Journal: Mol Endocrinol
Title: cAMP-dependent posttranscriptional regulation of steroidogenic acute regulatory (STAR) protein by the zinc finger protein ZFP36L1/TIS11b.
Volume: 23
Issue: 4
Pages: 497-509
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Publication
9326645 | J:43589
First Author: Caron KM
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia.
Volume: 94
Issue: 21
Pages: 11540-5
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Publication
20421306 | J:164545
First Author: Shridas P
Year: 2010
Journal: J Biol Chem
Title: Group X secretory phospholipase A2 regulates the expression of steroidogenic acute regulatory protein (StAR) in mouse adrenal glands.
Volume: 285
Issue: 26
Pages: 20031-9
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Publication
31373170 | J:294281
First Author: Su X
Year: 2019
Journal: J Cell Mol Med
Title: Cyclophilin D participates in the inhibitory effect of high-fat diet on the expression of steroidogenic acute regulatory protein.
Volume: 23
Issue: 10
Pages: 6859-6871
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Publication
21719703 | J:176626
First Author: Fukushima M
Year: 2011
Journal: J Biol Chem
Title: Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25), a negative regulator of luteinizing/chorionic gonadotropin hormone-induced steroidogenesis in Leydig cells: central role of steroidogenic acute regulatory protein (StAR).
Volume: 286
Issue: 34
Pages: 29932-40
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Publication
15498831 | J:95630
First Author: Hauet T
Year: 2005
Journal: Mol Endocrinol
Title: Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria.
Volume: 19
Issue: 2
Pages: 540-54
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Publication
36233310 | J:330267
 
First Author: Bouchard MF
Year: 2022
Journal: Int J Mol Sci
Title: A Short Promoter Region Containing Conserved Regulatory Motifs Is Required for Steroidogenic Acute Regulatory Protein (Star) Gene Expression in the Mouse Testis.
Volume: 23
Issue: 19
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Publication
8544843 | J:29227
First Author: Clark BJ
Year: 1995
Journal: Mol Endocrinol
Title: Hormonal and developmental regulation of the steroidogenic acute regulatory protein.
Volume: 9
Issue: 10
Pages: 1346-55
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Publication
17989356 | J:130735
First Author: Dyson MT
Year: 2008
Journal: Biol Reprod
Title: Mitochondrial A-kinase anchoring protein 121 binds type II protein kinase A and enhances steroidogenic acute regulatory protein-mediated steroidogenesis in MA-10 mouse leydig tumor cells.
Volume: 78
Issue: 2
Pages: 267-77
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Publication
22982292 | -
First Author: Beuck C
Year: 2012
Journal: J Mol Biol
Title: Structural analysis of the quaking homodimerization interface.
Volume: 423
Issue: 5
Pages: 766-81
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Protein Domain
IPR032377 | STAR_dimer
Type: Domain
Description: This entry represents the homodimerisation domain of the STAR (signal transducer and activator of RNA) proteins. Quaking is a prototypical member of the STAR family, which plays key roles in post-transcriptional gene regulation by controlling mRNA translation, stability and splicing []. Quaking-dimer is a helix-turn-helix dimer with an additional helix in the turn region. The dimerisation of quaking is required for adequate RNA-binding [].
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Publication
20223220 | -
First Author: Beuck C
Year: 2010
Journal: Structure
Title: Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation.
Volume: 18
Issue: 3
Pages: 377-89
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Publication
12351695 | J:79229
First Author: Ishii T
Year: 2002
Journal: Mol Endocrinol
Title: The roles of circulating high-density lipoproteins and trophic hormones in the phenotype of knockout mice lacking the steroidogenic acute regulatory protein.
Volume: 16
Issue: 10
Pages: 2297-309
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Publication
17050526 | J:117603
First Author: Liu J
Year: 2006
Journal: J Biol Chem
Title: Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis.
Volume: 281
Issue: 50
Pages: 38879-93
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Publication
15059956 | J:90743
First Author: Pisarska MD
Year: 2004
Journal: Endocrinology
Title: Forkhead l2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene.
Volume: 145
Issue: 7
Pages: 3424-33
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Publication
33130150 | J:331128
 
First Author: Razin T
Year: 2021
Journal: J Mol Cell Cardiol
Title: Interleukin-1α dependent survival of cardiac fibroblasts is associated with StAR/STARD1 expression and improved cardiac remodeling and function after myocardial infarction.
Volume: 155
Pages: 125-137
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Publication
22529212 | J:188654
First Author: Ishii T
Year: 2012
Journal: Endocrinology
Title: A genome-wide expression profile of adrenocortical cells in knockout mice lacking steroidogenic acute regulatory protein.
Volume: 153
Issue: 6
Pages: 2714-23
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Publication
28153708 | J:256274
First Author: Qiu Y
Year: 2017
Journal: Biochim Biophys Acta
Title: Steroidogenic acute regulatory protein (StAR) overexpression attenuates HFD-induced hepatic steatosis and insulin resistance.
Volume: 1863
Issue: 4
Pages: 978-990
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Publication
19793088 | J:155985
First Author: Büdefeld T
Year: 2009
Journal: Anat Histol Embryol
Title: Initiation of steroidogenesis precedes expression of cholesterologenic enzymes in the fetal mouse testes.
Volume: 38
Issue: 6
Pages: 461-6
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Publication
18276760 | J:136019
First Author: Nishida H
Year: 2008
Journal: Endocrinology
Title: Positive regulation of steroidogenic acute regulatory protein gene expression through the interaction between Dlx and GATA-4 for testicular steroidogenesis.
Volume: 149
Issue: 5
Pages: 2090-7
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Publication
32011766 | J:286995
First Author: Wang YQ
Year: 2020
Journal: Mol Reprod Dev
Title: An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy.
Volume: 87
Issue: 2
Pages: 223-230
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Publication
32301970 | J:292639
First Author: Cen C
Year: 2020
Journal: Biol Reprod
Title: Inactivation of Wt1 causes pre-granulosa cell to steroidogenic cell transformation and defect of ovary development†.
Volume: 103
Issue: 1
Pages: 60-69
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Publication
24265455 | J:208715
First Author: Manna PR
Year: 2014
Journal: Endocrinology
Title: Synergistic activation of steroidogenic acute regulatory protein expression and steroid biosynthesis by retinoids: involvement of cAMP/PKA signaling.
Volume: 155
Issue: 2
Pages: 576-91
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Publication
27146480 | J:233745
First Author: Ferrell JM
Year: 2016
Journal: J Lipid Res
Title: Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders.
Volume: 57
Issue: 7
Pages: 1144-54
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Protein Coding Gene
MGP_CAROLIEiJ_G0030931 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033489 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033469 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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