Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
StAR-related lipid transfer protein 5 (StARD5) contains a START domain that binds lipids, including sterols []. StARD5 primary binds bile acids, and may be involved in the transport of bile acids rather than cholesterol []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Soccio RE |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6. |
Volume: |
99 |
Issue: |
10 |
Pages: |
6943-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
213
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Létourneau D |
Year: |
2012 |
Journal: |
J Lipid Res |
Title: |
StAR-related lipid transfer domain protein 5 binds primary bile acids. |
Volume: |
53 |
Issue: |
12 |
Pages: |
2677-89 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
119
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
106
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
206
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Rodriguez-Agudo D |
Year: |
2019 |
Journal: |
J Lipid Res |
Title: |
StarD5: an ER stress protein regulates plasma membrane and intracellular cholesterol homeostasis. |
Volume: |
60 |
Issue: |
6 |
Pages: |
1087-1098 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen YC |
Year: |
2009 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Steroidogenic acute regulatory-related lipid transfer domain protein 5 localization and regulation in renal tubules. |
Volume: |
297 |
Issue: |
2 |
Pages: |
F380-8 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603910 |
|
Stage: |
TS10 |
Assay Id: |
MGI:2135266 |
Age: |
embryonic day 7.0 |
|
|
Specimen Label: |
E7 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603918 |
|
Stage: |
TS18 |
Assay Id: |
MGI:2135266 |
Age: |
embryonic day 11.0 |
|
|
Specimen Label: |
E11 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603923 |
|
Stage: |
TS23 |
Assay Id: |
MGI:2135266 |
Age: |
embryonic day 15.0 |
|
|
Specimen Label: |
E15 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603925 |
|
Stage: |
TS25 |
Assay Id: |
MGI:2135266 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
E17 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2135266 |
Age: |
postnatal adult |
|
|
Specimen Label: |
heart |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2135266 |
Age: |
postnatal adult |
|
|
Specimen Label: |
brain |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2135266 |
Age: |
postnatal adult |
|
|
Specimen Label: |
spleen |
Detected: |
false |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2135266 |
Age: |
postnatal adult |
|
|
Specimen Label: |
lung |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2135266 |
Age: |
postnatal adult |
|
|
Specimen Label: |
liver |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3598828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2135266 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Sk.m. |
Detected: |
false |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2135266 |
Age: |
postnatal adult |
|
|
Specimen Label: |
kidney |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2135241 |
Assay Type: |
Northern blot |
Annotation Date: |
2001-06-13 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2135266 |
Age: |
postnatal adult |
|
|
Specimen Label: |
testis |
Detected: |
false |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484728 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-05-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7484760 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7484728 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-05-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7484760 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
KO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7790731 |
Assay Type: |
Western blot |
Annotation Date: |
2024-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684619 |
|
Stage: |
TS19 |
Assay Id: |
MGI:7790771 |
Age: |
embryonic day 11.5 |
Image: |
5 |
|
Specimen Label: |
E11.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7790731 |
Assay Type: |
Western blot |
Annotation Date: |
2024-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7790771 |
Age: |
embryonic day 14.5 |
Image: |
5 |
|
Specimen Label: |
E14.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7790731 |
Assay Type: |
Western blot |
Annotation Date: |
2024-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684623 |
|
Stage: |
TS23 |
Assay Id: |
MGI:7790771 |
Age: |
embryonic day 15.5 |
Image: |
5 |
|
Specimen Label: |
E15.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7790731 |
Assay Type: |
Western blot |
Annotation Date: |
2024-12-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684627 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7790771 |
Age: |
postnatal day 3 |
Image: |
5 |
|
Specimen Label: |
3 dpp |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Romanowski MJ |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain. |
Volume: |
99 |
Issue: |
10 |
Pages: |
6949-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wines ME |
Year: |
2001 |
Journal: |
Genomics |
Title: |
Identification of mesoderm development (mesd) candidate genes by comparative mapping and genome sequence analysis. |
Volume: |
72 |
Issue: |
1 |
Pages: |
88-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van Dyck F |
Year: |
2007 |
Journal: |
Cell Metab |
Title: |
Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons. |
Volume: |
6 |
Issue: |
5 |
Pages: |
406-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adissu HA |
Year: |
2014 |
Journal: |
Dis Model Mech |
Title: |
Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. |
Volume: |
7 |
Issue: |
5 |
Pages: |
515-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo Y |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles. |
Volume: |
4 |
Issue: |
10 |
Pages: |
e7641 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kenney-Hunt JP |
Year: |
2006 |
Journal: |
Mamm Genome |
Title: |
Quantitative trait loci for body size components in mice. |
Volume: |
17 |
Issue: |
6 |
Pages: |
526-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schilling K |
Year: |
2009 |
Journal: |
Cerebellum |
Title: |
The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. |
Volume: |
8 |
Issue: |
4 |
Pages: |
477-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP) |
Year: |
2011 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Backcross DNA Panel Mapping Resource |
Year: |
1999 |
Journal: |
Database Release |
Title: |
JAX BSS Panel Mapping Data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ingham NJ |
Year: |
2019 |
Journal: |
PLoS Biol |
Title: |
Mouse screen reveals multiple new genes underlying mouse and human hearing loss. |
Volume: |
17 |
Issue: |
4 |
Pages: |
e3000194 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Soccio RE |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins. Activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress. |
Volume: |
280 |
Issue: |
19 |
Pages: |
19410-8 |
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Allele |
Name: |
transgene insertion IS65, GENSAT Project at Rockefeller University |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
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Allele |
Name: |
transgene insertion JX5852, Nathaniel Heintz |
Allele Type: |
Transgenic |
Attribute String: |
Reporter |
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Strain |
Attribute String: |
mutant stock, transgenic |
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Strain |
Attribute String: |
transgenic, mutant strain, congenic |
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Publication |
First Author: |
Bose HS |
Year: |
2008 |
Journal: |
Biochemistry |
Title: |
StAR-like activity and molten globule behavior of StARD6, a male germ-line protein. |
Volume: |
47 |
Issue: |
8 |
Pages: |
2277-88 |
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Protein Domain |
Type: |
Family |
Description: |
The steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domain is a protein module of approximately 210 residues that binds lipids, including sterols. The START domain consists of an alpha/beta helix-grip fold. Fifteen mammalian proteins, STARD1-STARD15, possess a START domain []. This entry includes StARD5 and StARD6.StAR-related lipid transfer protein 5 (StARD5) contains a START domain that binds lipids, including sterols []. StARD5 primary binds bile acids, and may be involved in the transport of bile acids rather than cholesterol [].StARD6 can bind cholesterol. It has cholesterol-transfer activity and StAR-like activity. STARD6 is restricted to the testes and is expressed during spermatogenesis in spermatids but not in steroidogenic cells [, ]. |
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