Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
61
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Svaren J |
Year: |
1997 |
Journal: |
Genomics |
Title: |
The Nab2 and Stat6 genes share a common transcription termination region. |
Volume: |
41 |
Issue: |
1 |
Pages: |
33-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaplan MH |
Year: |
2007 |
Journal: |
Blood |
Title: |
Constitutively active STAT6 predisposes toward a lymphoproliferative disorder. |
Volume: |
110 |
Issue: |
13 |
Pages: |
4367-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Finkelman FD |
Year: |
2000 |
Journal: |
J Immunol |
Title: |
Stat6 regulation of in vivo IL-4 responses. |
Volume: |
164 |
Issue: |
5 |
Pages: |
2303-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zamorano J |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
Proteolytic regulation of activated STAT6 by calpains. |
Volume: |
174 |
Issue: |
5 |
Pages: |
2843-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang J |
Year: |
2023 |
Journal: |
FASEB J |
Title: |
STAT6 suppression prevents bleomycin-induced dermal fibrosis. |
Volume: |
37 |
Issue: |
2 |
Pages: |
e22761 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takeda K |
Year: |
1996 |
Journal: |
Nature |
Title: |
Essential role of Stat6 in IL-4 signalling. |
Volume: |
380 |
Issue: |
6575 |
Pages: |
627-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tamachi T |
Year: |
2009 |
Journal: |
Biochem Biophys Res Commun |
Title: |
STAT6 inhibits T-bet-independent Th1 cell differentiation. |
Volume: |
382 |
Issue: |
4 |
Pages: |
751-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Malaviya R |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Role of STAT6 in IgE receptor/FcepsilonRI-mediated late phase allergic responses of mast cells. |
Volume: |
168 |
Issue: |
1 |
Pages: |
421-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen HC |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Live cell imaging reveals continuous STAT6 nuclear trafficking. |
Volume: |
185 |
Issue: |
1 |
Pages: |
64-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shimoda K |
Year: |
1996 |
Journal: |
Nature |
Title: |
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. |
Volume: |
380 |
Issue: |
6575 |
Pages: |
630-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen W |
Year: |
2004 |
Journal: |
J Immunol |
Title: |
Methylation of STAT6 modulates STAT6 phosphorylation, nuclear translocation, and DNA-binding activity. |
Volume: |
172 |
Issue: |
11 |
Pages: |
6744-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Davey EJ |
Year: |
2000 |
Journal: |
Int Immunol |
Title: |
STAT6 is required for the regulation of IL-4-induced cytoskeletal events in B cells. |
Volume: |
12 |
Issue: |
7 |
Pages: |
995-1003 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yukawa K |
Year: |
2005 |
Journal: |
Int J Mol Med |
Title: |
STAT6 deficiency inhibits tubulointerstitial fibrosis in obstructive nephropathy. |
Volume: |
15 |
Issue: |
2 |
Pages: |
225-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bruns HA |
Year: |
2003 |
Journal: |
J Immunol |
Title: |
Expression of a constitutively active Stat6 in vivo alters lymphocyte homeostasis with distinct effects in T and B cells. |
Volume: |
170 |
Issue: |
7 |
Pages: |
3478-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haase P |
Year: |
2020 |
Journal: |
Eur J Immunol |
Title: |
Modulation of the humoral immune response by constitutively active STAT6 expression in murine B cells. |
Volume: |
50 |
Issue: |
4 |
Pages: |
558-567 |
|
•
•
•
•
•
|
Publication |
First Author: |
Urban JF Jr |
Year: |
1998 |
Journal: |
Immunity |
Title: |
IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. |
Volume: |
8 |
Issue: |
2 |
Pages: |
255-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sahoo A |
Year: |
2014 |
Journal: |
Nat Commun |
Title: |
Grail controls Th2 cell development by targeting STAT6 for degradation. |
Volume: |
5 |
|
Pages: |
4732 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schubart C |
Year: |
2019 |
Journal: |
Mucosal Immunol |
Title: |
Selective expression of constitutively activated STAT6 in intestinal epithelial cells promotes differentiation of secretory cells and protection against helminths. |
Volume: |
12 |
Issue: |
2 |
Pages: |
413-424 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fritz DK |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
A mouse model of airway disease: oncostatin M-induced pulmonary eosinophilia, goblet cell hyperplasia, and airway hyperresponsiveness are STAT6 dependent, and interstitial pulmonary fibrosis is STAT6 independent. |
Volume: |
186 |
Issue: |
2 |
Pages: |
1107-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burgis S |
Year: |
2007 |
Journal: |
Int Arch Allergy Immunol |
Title: |
Unexpected phenotype of STAT6 heterozygous mice implies distinct STAT6 dosage requirements for different IL-4 functions. |
Volume: |
143 |
Issue: |
4 |
Pages: |
263-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu X |
Year: |
2008 |
Journal: |
Blood |
Title: |
PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling. |
Volume: |
112 |
Issue: |
10 |
Pages: |
4098-108 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sahoo A |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Stat6 and c-Jun mediate Th2 cell-specific IL-24 gene expression. |
Volume: |
186 |
Issue: |
7 |
Pages: |
4098-109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Simovic MO |
Year: |
2007 |
Journal: |
J Surg Res |
Title: |
The STAT4 and STAT6 pathways in pancreatitis-associated lung injury. |
Volume: |
137 |
Issue: |
1 |
Pages: |
10-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohmori Y |
Year: |
1997 |
Journal: |
J Immunol |
Title: |
IL-4-induced STAT6 suppresses IFN-gamma-stimulated STAT1-dependent transcription in mouse macrophages. |
Volume: |
159 |
Issue: |
11 |
Pages: |
5474-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2018 |
Journal: |
J Immunol |
Title: |
STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells. |
Volume: |
201 |
Issue: |
9 |
Pages: |
2612-2623 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mirmonsef P |
Year: |
1999 |
Journal: |
J Immunol |
Title: |
Inhibition of Kit expression by IL-4 and IL-10 in murine mast cells: role of STAT6 and phosphatidylinositol 3'-kinase. |
Volume: |
163 |
Issue: |
5 |
Pages: |
2530-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Linehan LA |
Year: |
1998 |
Journal: |
J Immunol |
Title: |
STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination. |
Volume: |
161 |
Issue: |
1 |
Pages: |
302-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu T |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24. |
Volume: |
10 |
Issue: |
1 |
Pages: |
4353 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wermeling F |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Acute inflammation primes myeloid effector cells for anti-inflammatory STAT6 signaling. |
Volume: |
110 |
Issue: |
33 |
Pages: |
13487-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Symowski C |
Year: |
2019 |
Journal: |
Eur J Immunol |
Title: |
Th2 cell-derived IL-4/IL-13 promote ILC2 accumulation in the lung by ILC2-intrinsic STAT6 signaling in mice. |
Volume: |
49 |
Issue: |
9 |
Pages: |
1421-1432 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thieu VT |
Year: |
2007 |
Journal: |
J Leukoc Biol |
Title: |
IL-4-stimulated NF-kappaB activity is required for Stat6 DNA binding. |
Volume: |
82 |
Issue: |
2 |
Pages: |
370-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goenka S |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Selective potentiation of Stat-dependent gene expression by collaborator of Stat6 (CoaSt6), a transcriptional cofactor. |
Volume: |
103 |
Issue: |
11 |
Pages: |
4210-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki K |
Year: |
2002 |
Journal: |
J Exp Med |
Title: |
Proteolytic processing of Stat6 signaling in mast cells as a negative regulatory mechanism. |
Volume: |
196 |
Issue: |
1 |
Pages: |
27-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen H |
Year: |
2011 |
Journal: |
Cell |
Title: |
Activation of STAT6 by STING is critical for antiviral innate immunity. |
Volume: |
147 |
Issue: |
2 |
Pages: |
436-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cetkovic-Cvrlje M |
Year: |
2005 |
Journal: |
Clin Immunol |
Title: |
Effect of targeted disruption of signal transducer and activator of transcription (Stat)4 and Stat6 genes on the autoimmune diabetes development induced by multiple low doses of streptozotocin. |
Volume: |
114 |
Issue: |
3 |
Pages: |
299-306 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chapoval SP |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
STAT6 expression in multiple cell types mediates the cooperative development of allergic airway disease. |
Volume: |
186 |
Issue: |
4 |
Pages: |
2571-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leon-Cabrera SA |
Year: |
2017 |
Journal: |
Cancer Immunol Res |
Title: |
Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer. |
Volume: |
5 |
Issue: |
5 |
Pages: |
385-396 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bunting KD |
Year: |
2004 |
Journal: |
J Leukoc Biol |
Title: |
Increased numbers of committed myeloid progenitors but not primitive hematopoietic stem/progenitors in mice lacking STAT6 expression. |
Volume: |
76 |
Issue: |
2 |
Pages: |
484-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kochanowsky JA |
Year: |
2023 |
Journal: |
PLoS Pathog |
Title: |
ROP16-mediated activation of STAT6 enhances cyst development of type III Toxoplasma gondii in neurons. |
Volume: |
19 |
Issue: |
4 |
Pages: |
e1011347 |
|
•
•
•
•
•
|
Publication |
First Author: |
Akiho H |
Year: |
2002 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Role of IL-4, IL-13, and STAT6 in inflammation-induced hypercontractility of murine smooth muscle cells. |
Volume: |
282 |
Issue: |
2 |
Pages: |
G226-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu J |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
Stat6 is necessary and sufficient for IL-4's role in Th2 differentiation and cell expansion. |
Volume: |
166 |
Issue: |
12 |
Pages: |
7276-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Darcan-Nicolaisen Y |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Small interfering RNA against transcription factor STAT6 inhibits allergic airway inflammation and hyperreactivity in mice. |
Volume: |
182 |
Issue: |
12 |
Pages: |
7501-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pillemer BB |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
STAT6 activation confers upon T helper cells resistance to suppression by regulatory T cells. |
Volume: |
183 |
Issue: |
1 |
Pages: |
155-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fleming BD |
Year: |
2015 |
Journal: |
J Leukoc Biol |
Title: |
The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling. |
Volume: |
98 |
Issue: |
3 |
Pages: |
395-407 |
|
•
•
•
•
•
|
Publication |
First Author: |
Metwali A |
Year: |
2021 |
Journal: |
Eur J Immunol |
Title: |
Helminth-induced regulation of T-cell transfer colitis requires intact and regulated T cell Stat6 signaling in mice. |
Volume: |
51 |
Issue: |
2 |
Pages: |
433-444 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2022 |
Journal: |
Cell Death Dis |
Title: |
STAT6 contributes to renal fibrosis by modulating PPARα-mediated tubular fatty acid oxidation. |
Volume: |
13 |
Issue: |
1 |
Pages: |
66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang Y |
Year: |
2022 |
Journal: |
Cell Death Dis |
Title: |
STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway. |
Volume: |
13 |
Issue: |
6 |
Pages: |
530 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang Z |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
IFN-gamma suppresses STAT6 phosphorylation by inhibiting its recruitment to the IL-4 receptor. |
Volume: |
174 |
Issue: |
3 |
Pages: |
1332-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaplan MH |
Year: |
1996 |
Journal: |
Immunity |
Title: |
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells. |
Volume: |
4 |
Issue: |
3 |
Pages: |
313-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiong X |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Sirtuin 6 maintains epithelial STAT6 activity to support intestinal tuft cell development and type 2 immunity. |
Volume: |
13 |
Issue: |
1 |
Pages: |
5192 |
|
•
•
•
•
•
|
Publication |
First Author: |
Svaren J |
Year: |
1996 |
Journal: |
Mol Cell Biol |
Title: |
NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli. |
Volume: |
16 |
Issue: |
7 |
Pages: |
3545-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Darnell JE Jr |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Reflections on STAT3, STAT5, and STAT6 as fat STATs. |
Volume: |
93 |
Issue: |
13 |
Pages: |
6221-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Singh RR |
Year: |
2003 |
Journal: |
J Immunol |
Title: |
Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis. |
Volume: |
170 |
Issue: |
9 |
Pages: |
4818-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Q |
Year: |
2004 |
Journal: |
Infect Immun |
Title: |
Simultaneous deficiency in CD28 and STAT6 results in chronic ectoparasite-induced inflammatory skin disease. |
Volume: |
72 |
Issue: |
7 |
Pages: |
3706-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dorsey NJ |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
STAT6 controls the number of regulatory T cells in vivo, thereby regulating allergic lung inflammation. |
Volume: |
191 |
Issue: |
4 |
Pages: |
1517-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kriebel P |
Year: |
1999 |
Journal: |
Oncogene |
Title: |
Consequences of Stat6 deletion on Sis/PDGF- and IL-4-induced proliferation and transcriptional activation in murine fibroblasts. |
Volume: |
18 |
Issue: |
51 |
Pages: |
7294-302 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rosen MJ |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines. |
Volume: |
190 |
Issue: |
4 |
Pages: |
1849-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andrews RP |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Analysis of the life cycle of stat6. Continuous cycling of STAT6 is required for IL-4 signaling. |
Volume: |
277 |
Issue: |
39 |
Pages: |
36563-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tekkanat KK |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
IL-13-induced airway hyperreactivity during respiratory syncytial virus infection is STAT6 dependent. |
Volume: |
166 |
Issue: |
5 |
Pages: |
3542-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chitnis T |
Year: |
2001 |
Journal: |
J Clin Invest |
Title: |
Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis. |
Volume: |
108 |
Issue: |
5 |
Pages: |
739-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Makita S |
Year: |
2021 |
Journal: |
J Invest Dermatol |
Title: |
T-bet and STAT6 Coordinately Suppress the Development of IL-9-Mediated Atopic Dermatitis-Like Skin Inflammation in Mice. |
Volume: |
141 |
Issue: |
5 |
Pages: |
1274-1285.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Archambaud C |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat(Y136F) mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells. |
Volume: |
182 |
Issue: |
5 |
Pages: |
2680-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kapoor N |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
Transcription factors STAT6 and KLF4 implement macrophage polarization via the dual catalytic powers of MCPIP. |
Volume: |
194 |
Issue: |
12 |
Pages: |
6011-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shen XD |
Year: |
2003 |
Journal: |
Hepatology |
Title: |
Stat4 and Stat6 signaling in hepatic ischemia/reperfusion injury in mice: HO-1 dependence of Stat4 disruption-mediated cytoprotection. |
Volume: |
37 |
Issue: |
2 |
Pages: |
296-303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin Y |
Year: |
2019 |
Journal: |
Mucosal Immunol |
Title: |
Non-hematopoietic STAT6 induces epithelial tight junction dysfunction and promotes intestinal inflammation and tumorigenesis. |
Volume: |
12 |
Issue: |
6 |
Pages: |
1304-1315 |
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Publication |
First Author: |
Yokota N |
Year: |
2003 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Contrasting roles for STAT4 and STAT6 signal transduction pathways in murine renal ischemia-reperfusion injury. |
Volume: |
285 |
Issue: |
2 |
Pages: |
F319-25 |
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Publication |
First Author: |
Olsan EE |
Year: |
2018 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Identification of targets of IL-13 and STAT6 signaling in polycystic kidney disease. |
Volume: |
315 |
Issue: |
1 |
Pages: |
F86-F96 |
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Publication |
First Author: |
Jin D |
Year: |
2009 |
Journal: |
Immunology |
Title: |
STAT6 signalling is important in CD8 T-cell activation and defence against Toxoplasma gondii infection in the brain. |
Volume: |
127 |
Issue: |
2 |
Pages: |
187-95 |
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Publication |
First Author: |
Dedeoglu F |
Year: |
2004 |
Journal: |
Int Immunol |
Title: |
Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB. |
Volume: |
16 |
Issue: |
3 |
Pages: |
395-404 |
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Publication |
First Author: |
Yan D |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation. |
Volume: |
16 |
Issue: |
11 |
Pages: |
2914-2927 |
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Publication |
First Author: |
Jacob CO |
Year: |
2003 |
Journal: |
J Immunol |
Title: |
Pivotal role of Stat4 and Stat6 in the pathogenesis of the lupus-like disease in the New Zealand mixed 2328 mice. |
Volume: |
171 |
Issue: |
3 |
Pages: |
1564-71 |
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Publication |
First Author: |
Czimmerer Z |
Year: |
2018 |
Journal: |
Immunity |
Title: |
The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages. |
Volume: |
48 |
Issue: |
1 |
Pages: |
75-90.e6 |
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Publication |
First Author: |
Nabeshima Y |
Year: |
2005 |
Journal: |
FEBS Lett |
Title: |
IL-4 modulates the histamine content of mast cells in a mast cell/fibroblast co-culture through a Stat6 signaling pathway in fibroblasts. |
Volume: |
579 |
Issue: |
29 |
Pages: |
6653-8 |
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Publication |
First Author: |
Miyata S |
Year: |
1999 |
Journal: |
Clin Exp Allergy |
Title: |
STAT6 deficiency in a mouse model of allergen-induced airways inflammation abolishes eosinophilia but induces infiltration of CD8+ T cells. |
Volume: |
29 |
Issue: |
1 |
Pages: |
114-23 |
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Publication |
First Author: |
Li G |
Year: |
2012 |
Journal: |
Free Radic Biol Med |
Title: |
8-Oxoguanine-DNA glycosylase 1 deficiency modifies allergic airway inflammation by regulating STAT6 and IL-4 in cells and in mice. |
Volume: |
52 |
Issue: |
2 |
Pages: |
392-401 |
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Publication |
First Author: |
Zhou P |
Year: |
2000 |
Journal: |
J Immunol |
Title: |
Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance. |
Volume: |
165 |
Issue: |
10 |
Pages: |
5580-7 |
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Publication |
First Author: |
Zhao M |
Year: |
2022 |
Journal: |
Immunity |
Title: |
Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C. |
Volume: |
55 |
Issue: |
4 |
Pages: |
623-638.e5 |
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Publication |
First Author: |
Szanto A |
Year: |
2010 |
Journal: |
Immunity |
Title: |
STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells. |
Volume: |
33 |
Issue: |
5 |
Pages: |
699-712 |
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Publication |
First Author: |
Sasaki K |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Stat6 signaling suppresses VLA-4 expression by CD8+ T cells and limits their ability to infiltrate tumor lesions in vivo. |
Volume: |
181 |
Issue: |
1 |
Pages: |
104-8 |
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Publication |
First Author: |
Matsukawa A |
Year: |
2001 |
Journal: |
J Exp Med |
Title: |
Pivotal role of signal transducer and activator of transcription (Stat)4 and Stat6 in the innate immune response during sepsis. |
Volume: |
193 |
Issue: |
6 |
Pages: |
679-88 |
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Publication |
First Author: |
Rose S |
Year: |
2006 |
Journal: |
Eur J Immunol |
Title: |
The key regulators of adult T helper cell responses, STAT6 and T-bet, are established in early life in mice. |
Volume: |
36 |
Issue: |
5 |
Pages: |
1241-53 |
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Publication |
First Author: |
Kauffmann F |
Year: |
2018 |
Journal: |
Front Immunol |
Title: |
STAT6 Mediates Footpad Immunopathology in the Absence of IL-12p40 Following Infection of Susceptible BALB/c Mice With Leishmania major. |
Volume: |
9 |
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Pages: |
503 |
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Publication |
First Author: |
Land KJ |
Year: |
2006 |
Journal: |
Endocrinology |
Title: |
Differential requirement of signal transducer and activator of transcription-4 (Stat4) and Stat6 in a thyrotropin receptor-289-adenovirus-induced model of Graves' hyperthyroidism. |
Volume: |
147 |
Issue: |
1 |
Pages: |
111-9 |
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Publication |
First Author: |
Ford AQ |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
An atopy-associated polymorphism in the ectodomain of the IL-4R(alpha) chain (V50) regulates the persistence of STAT6 phosphorylation. |
Volume: |
183 |
Issue: |
3 |
Pages: |
1607-16 |
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Publication |
First Author: |
Madden KB |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Role of STAT6 and mast cells in IL-4- and IL-13-induced alterations in murine intestinal epithelial cell function. |
Volume: |
169 |
Issue: |
8 |
Pages: |
4417-22 |
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Publication |
First Author: |
van Panhuys N |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation. |
Volume: |
105 |
Issue: |
34 |
Pages: |
12423-8 |
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Publication |
First Author: |
Delgado-Ramirez Y |
Year: |
2021 |
Journal: |
Int J Mol Sci |
Title: |
STAT6 Is Critical for the Induction of Regulatory T Cells In Vivo Controlling the Initial Steps of Colitis-Associated Cancer. |
Volume: |
22 |
Issue: |
8 |
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Publication |
First Author: |
Kochanowsky JA |
Year: |
2021 |
Journal: |
mBio |
Title: |
ROP16-Mediated Activation of STAT6 Suppresses Host Cell Reactive Oxygen Species Production, Facilitating Type III Toxoplasma gondii Growth and Survival. |
Volume: |
12 |
Issue: |
2 |
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Publication |
First Author: |
Jayakumar A |
Year: |
2017 |
Journal: |
Neoplasia |
Title: |
Stat6 Promotes Intestinal Tumorigenesis in a Mouse Model of Adenomatous Polyposis by Expansion of MDSCs and Inhibition of Cytotoxic CD8 Response. |
Volume: |
19 |
Issue: |
8 |
Pages: |
595-605 |
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