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Search results 1 to 100 out of 696 for Sting1

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
340061 | STING1
Type: gene
Organism: human
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Gene
100127621 | sting1
Type: gene
Organism: frog, western clawed
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Gene
498840 | Sting1
Type: gene
Organism: rat
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Gene
462107 | STING1
Type: gene
Organism: chimpanzee
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Gene
606815 | STING1
Type: gene
Organism: dog, domestic
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Gene
533661 | STING1
Type: gene
Organism: cattle
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Gene
101243556 | sting1
Type: gene
Organism: zebrafish
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Gene
694353 | STING1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1919762 | Sting1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
38016467 | J:352741
First Author: Zhang R
Year: 2023
Journal: Immunity
Title: Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis.
Volume: 56
Issue: 12
Pages: 2736-2754.e8
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Gene
63932 | STEEP1
Type: gene
Organism: human
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Publication
36037380 | J:344199
First Author: Pais TF
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Brain endothelial STING1 activation by Plasmodium-sequestered heme promotes cerebral malaria via type I IFN response.
Volume: 119
Issue: 36
Pages: e2206327119
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Gene
728024 | LOC728024
Type: gene
Organism: human
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Publication
35769880 | J:359993
First Author: Chen F
Year: 2022
Journal: iScience
Title: The STING1-MYD88 complex drives ACOD1/IRG1 expression and function in lethal innate immunity.
Volume: 25
Issue: 7
Pages: 104561
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Protein Coding Gene
MGI:1924894 | Steep1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
313433 | Steep1
Type: gene
Organism: rat
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Gene
492094 | STEEP1
Type: gene
Organism: dog, domestic
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Gene
473760 | STEEP1
Type: gene
Organism: chimpanzee
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Gene
504687 | STEEP1
Type: gene
Organism: cattle
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Gene
428719 | STEEP1
Type: gene
Organism: chicken
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Gene
447921 | steep1
Type: gene
Organism: zebrafish
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Gene
693764 | STEEP1
Type: gene
Organism: macaque, rhesus
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Gene
394969 | steep1
Type: gene
Organism: frog, western clawed
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Publication
34290407 | J:326430
First Author: Chu TT
Year: 2021
Journal: Nature
Title: Tonic prime-boost of STING signalling mediates Niemann-Pick disease type C.
Volume: 596
Issue: 7873
Pages: 570-575
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Protein Coding Gene
MGP_CAROLIEiJ_G0022117 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024270 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024236 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024204 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024236 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024003 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1919762 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024677 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023478 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023971 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024103 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024185 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024098 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024726 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023222 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023541 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018851 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023029 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
18559423 | J:139751
First Author: Jin L
Year: 2008
Journal: Mol Cell Biol
Title: MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals.
Volume: 28
Issue: 16
Pages: 5014-26
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Publication
18724357 | J:141011
First Author: Ishikawa H
Year: 2008
Journal: Nature
Title: STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.
Volume: 455
Issue: 7213
Pages: 674-8
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Publication
19776740 | J:153502
First Author: Ishikawa H
Year: 2009
Journal: Nature
Title: STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity.
Volume: 461
Issue: 7265
Pages: 788-92
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Publication
19433799 | J:150011
First Author: Sun W
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization.
Volume: 106
Issue: 21
Pages: 8653-8
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Publication
21947006 | J:196251
First Author: Burdette DL
Year: 2011
Journal: Nature
Title: STING is a direct innate immune sensor of cyclic di-GMP.
Volume: 478
Issue: 7370
Pages: 515-8
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Publication
23258412 | J:196209
First Author: Wu J
Year: 2013
Journal: Science
Title: Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Volume: 339
Issue: 6121
Pages: 826-30
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Publication
26300263 | J:227350
First Author: Kranzusch PJ
Year: 2015
Journal: Mol Cell
Title: Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Volume: 59
Issue: 6
Pages: 891-903
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Publication
26669264 | J:233616
 
First Author: Zhang H
Year: 2015
Journal: Sci Rep
Title: Rat and human STINGs profile similarly towards anticancer/antiviral compounds.
Volume: 5
Pages: 18035
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Publication
27324217 | J:239879
 
First Author: Mukai K
Year: 2016
Journal: Nat Commun
Title: Activation of STING requires palmitoylation at the Golgi.
Volume: 7
Pages: 11932
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Publication
29973723 | J:319678
First Author: Haag SM
Year: 2018
Journal: Nature
Title: Targeting STING with covalent small-molecule inhibitors.
Volume: 559
Issue: 7713
Pages: 269-273
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Publication
32126128 | J:292408
First Author: Yang B
Year: 2020
Journal: PLoS Pathog
Title: RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation.
Volume: 16
Issue: 3
Pages: e1008387
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Publication
28542326 | J:336570
First Author: Chan B
Year: 2017
Journal: PLoS Pathog
Title: The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription.
Volume: 13
Issue: 5
Pages: e1006382
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Publication
35712074 | J:327508
First Author: Tan HY
Year: 2022
Journal: iScience
Title: cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model.
Volume: 25
Issue: 6
Pages: 104404
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Publication
27927967 | J:247744
First Author: Patel S
Year: 2017
Journal: J Immunol
Title: The Common R71H-G230A-R293Q Human TMEM173 Is a Null Allele.
Volume: 198
Issue: 2
Pages: 776-787
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Publication
38690737 | J:348089
 
First Author: Defaye M
Year: 2024
Journal: J Clin Invest
Title: Induction of antiviral interferon-stimulated genes by neuronal STING promotes the resolution of pain in mice.
Volume: 134
Issue: 9
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Publication
29985392 | J:266322
First Author: Torralba D
Year: 2018
Journal: Nat Commun
Title: Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts.
Volume: 9
Issue: 1
Pages: 2658
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Publication
33440157 | J:352691
First Author: Budhu S
Year: 2021
Journal: Cell Rep
Title: Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Volume: 34
Issue: 2
Pages: 108620
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Publication
30886058 | J:273012
First Author: Wu J
Year: 2019
Journal: J Exp Med
Title: STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death.
Volume: 216
Issue: 4
Pages: 867-883
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Publication
33483762 | J:328887
First Author: Akazawa S
Year: 2021
Journal: Diabetologia
Title: Deficiency of the innate immune adaptor STING promotes autoreactive T cell expansion in NOD mice.
Volume: 64
Issue: 4
Pages: 878-889
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Publication
34156982 | J:313006
 
First Author: Anastasiou M
Year: 2021
Journal: JCI Insight
Title: Endothelial STING controls T cell transmigration in an IFNI-dependent manner.
Volume: 6
Issue: 15
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Publication
37555319 | J:353733
First Author: Chakraborty A
Year: 2023
Journal: Circulation
Title: Epigenetic Induction of Smooth Muscle Cell Phenotypic Alterations in Aortic Aneurysms and Dissections.
Volume: 148
Issue: 12
Pages: 959-977
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Publication
25898005 | J:269464
   
First Author: Blaauboer SM
Year: 2015
Journal: Elife
Title: The mucosal adjuvant cyclic di-GMP enhances antigen uptake and selectively activates pinocytosis-efficient cells in vivo.
Volume: 4
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Publication
21098106 | J:168746
First Author: Sauer JD
Year: 2011
Journal: Infect Immun
Title: The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides.
Volume: 79
Issue: 2
Pages: 688-94
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Publication
34162937 | J:323693
First Author: Nunokawa H
Year: 2021
Journal: Sci Rep
Title: Crucial role of stimulator of interferon genes-dependent signaling in house dust mite extract-induced IgE production.
Volume: 11
Issue: 1
Pages: 13157
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Publication
23585680 | J:202559
First Author: Conlon J
Year: 2013
Journal: J Immunol
Title: Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid.
Volume: 190
Issue: 10
Pages: 5216-25
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Publication
26311879 | J:230082
First Author: Parker ZM
Year: 2015
Journal: J Virol
Title: Role of the DNA Sensor STING in Protection from Lethal Infection following Corneal and Intracerebral Challenge with Herpes Simplex Virus 1.
Volume: 89
Issue: 21
Pages: 11080-91
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Publication
34010139 | J:333769
 
First Author: Humphries F
Year: 2021
Journal: Sci Immunol
Title: A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection.
Volume: 6
Issue: 59
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Publication
30894428 | J:274892
First Author: Guimarães ES
Year: 2019
Journal: J Immunol
Title: Brucella abortus Cyclic Dinucleotides Trigger STING-Dependent Unfolded Protein Response That Favors Bacterial Replication.
Volume: 202
Issue: 9
Pages: 2671-2681
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Publication
29593264 | J:260479
First Author: Takahashi A
Year: 2018
Journal: Nat Commun
Title: Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.
Volume: 9
Issue: 1
Pages: 1249
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Publication
37583703 | J:352695
 
First Author: Chen Y
Year: 2023
Journal: Front Immunol
Title: Gelsevirine is a novel STING-specific inhibitor and mitigates STING-related inflammation in sepsis.
Volume: 14
Pages: 1190707
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Publication
30482774 | J:352690
First Author: Shen J
Year: 2019
Journal: Cancer Res
Title: PARPi Triggers the STING-Dependent Immune Response and Enhances the Therapeutic Efficacy of Immune Checkpoint Blockade Independent of BRCAness.
Volume: 79
Issue: 2
Pages: 311-319
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Publication
36949064 | J:352693
First Author: Falahat R
Year: 2023
Journal: Nat Commun
Title: Epigenetic state determines the in vivo efficacy of STING agonist therapy.
Volume: 14
Issue: 1
Pages: 1573
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Publication
34158841 | J:352692
First Author: Li Y
Year: 2021
Journal: Theranostics
Title: Plasma-derived DNA containing-extracellular vesicles induce STING-mediated proinflammatory responses in dermatomyositis.
Volume: 11
Issue: 15
Pages: 7144-7158
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Publication
38994929 | J:352682
 
First Author: Akhavan D
Year: 2024
Journal: Cells
Title: Evaluation of the Immunomodulatory Effects of Radiation for Chimeric Antigen Receptor T Cell Therapy in Glioblastoma Multiforme.
Volume: 13
Issue: 13
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Publication
38848078 | J:352681
First Author: Lyu S
Year: 2024
Journal: Invest Ophthalmol Vis Sci
Title: Involvement of cGAS/STING Signaling in the Pathogenesis of Candida albicans Keratitis: Insights From Genetic and Pharmacological Approaches.
Volume: 65
Issue: 6
Pages: 13
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Publication
36943863 | J:352680
First Author: Shi J
Year: 2023
Journal: STAR Protoc
Title: Protocol for the identification and expression analysis of a cytoplasmic membrane-localized protein STING.
Volume: 4
Issue: 2
Pages: 102172
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Publication
34453520 | J:321648
 
First Author: Wang Q
Year: 2021
Journal: Endocrinology
Title: Differential Effects of Viral Nucleic Acid Sensor Signaling Pathways on Testicular Sertoli and Leydig Cells.
Volume: 162
Issue: 12
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Publication
35394877 | J:352738
First Author: Hinkle JT
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy.
Volume: 119
Issue: 15
Pages: e2118819119
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Publication
31887080 | J:300077
First Author: Luo W
Year: 2020
Journal: Circulation
Title: Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture.
Volume: 141
Issue: 1
Pages: 42-66
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Publication
37379835 | J:352739
First Author: Chen T
Year: 2023
Journal: Immunity
Title: The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity.
Volume: 56
Issue: 8
Pages: 1727-1742.e6
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Publication
30561388 | J:270471
First Author: Yu Y
Year: 2019
Journal: J Clin Invest
Title: STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis.
Volume: 129
Issue: 2
Pages: 546-555
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Publication
37277149 | J:338416
 
First Author: Marino G
Year: 2023
Journal: Life Sci Alliance
Title: STING is redundant for host defense and pathology of COVID-19-like disease in mice.
Volume: 6
Issue: 8
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Publication
37948864 | J:343476
First Author: He YQ
Year: 2023
Journal: Int Immunopharmacol
Title: Ursodeoxycholic acid alleviates sepsis-induced lung injury by blocking PANoptosis via STING pathway.
Volume: 125
Issue: Pt B
Pages: 111161
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Publication
38918759 | J:352321
First Author: Ni B
Year: 2024
Journal: J Neuroinflammation
Title: Therapeutic intervention in neuroinflammation for neovascular ocular diseases through targeting the cGAS-STING-necroptosis pathway.
Volume: 21
Issue: 1
Pages: 164
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Publication
34877494 | J:351388
First Author: Morozzi G
Year: 2021
Journal: iScience
Title: STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia.
Volume: 24
Issue: 12
Pages: 103434
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Publication
32969062 | J:307003
First Author: Yu Y
Year: 2020
Journal: FASEB J
Title: STING controls intestinal homeostasis through promoting antimicrobial peptide expression in epithelial cells.
Volume: 34
Issue: 11
Pages: 15417-15430
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Publication
32582187 | J:306691
 
First Author: Tansakul M
Year: 2020
Journal: Front Immunol
Title: Deficiency of STING Promotes Collagen-Specific Antibody Production and B Cell Survival in Collagen-Induced Arthritis.
Volume: 11
Pages: 1101
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Publication
37345657 | J:338564
 
First Author: Liu H
Year: 2023
Journal: JCI Insight
Title: Activated cGAS/STING signaling elicits endothelial cell senescence in early diabetic retinopathy.
Volume: 8
Issue: 12
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Publication
38428828 | J:350892
 
First Author: Zhao QX
Year: 2024
Journal: Biochem Pharmacol
Title: STING deficiency alleviates ferroptosis through FPN1 stabilization in diabetic kidney disease.
Volume: 222
Pages: 116102
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Publication
36467059 | J:331994
 
First Author: Gong LK
Year: 2022
Journal: Front Pharmacol
Title: Low-dose ganciclovir ameliorates dextran sulfate sodium-induced ulcerative colitis through inhibiting macrophage STING activation in mice.
Volume: 13
Pages: 1020670
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Publication
25320273 | J:296050
First Author: Zhu Q
Year: 2014
Journal: J Immunol
Title: Cutting edge: STING mediates protection against colorectal tumorigenesis by governing the magnitude of intestinal inflammation.
Volume: 193
Issue: 10
Pages: 4779-82
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Publication
31582793 | J:284295
First Author: Martin GR
Year: 2019
Journal: Sci Rep
Title: Stimulator of interferon genes (STING) activation exacerbates experimental colitis in mice.
Volume: 9
Issue: 1
Pages: 14281
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Publication
38149573 | J:344171
First Author: Li ZC
Year: 2023
Journal: Int Immunopharmacol
Title: Sting mutation attenuates acetaminophen-induced acute liver injury by limiting NLRP3 activation.
Volume: 125
Issue: Pt A
Pages: 111133
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Publication
28743914 | J:252921
First Author: Guo X
Year: 2017
Journal: Sci Rep
Title: Cyclic GMP-AMP Ameliorates Diet-induced Metabolic Dysregulation and Regulates Proinflammatory Responses Distinctly from STING Activation.
Volume: 7
Issue: 1
Pages: 6355
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Publication
27334590 | J:235950
First Author: Lio CW
Year: 2016
Journal: J Virol
Title: cGAS-STING Signaling Regulates Initial Innate Control of Cytomegalovirus Infection.
Volume: 90
Issue: 17
Pages: 7789-97
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Publication
29046432 | J:248299
 
First Author: Zeng L
Year: 2017
Journal: Sci Transl Med
Title: ALK is a therapeutic target for lethal sepsis.
Volume: 9
Issue: 412
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Publication
23378430 | J:193614
First Author: Jin L
Year: 2013
Journal: J Immunol
Title: STING/MPYS mediates host defense against Listeria monocytogenes infection by regulating Ly6C(hi) monocyte migration.
Volume: 190
Issue: 6
Pages: 2835-43
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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