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Search results 1 to 100 out of 477 for Stk11

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Type Details Score
Gene
6794 | STK11
Type: gene
Organism: human
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Gene
100337329 | STK11
Type: gene
Organism: cattle
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Gene
420105 | STK11
Type: gene
Organism: chicken
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Gene
550537 | stk11
Type: gene
Organism: zebrafish
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Gene
705686 | STK11
Type: gene
Organism: macaque, rhesus
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Gene
549287 | stk11
Type: gene
Organism: frog, western clawed
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Gene
314621 | Stk11
Type: gene
Organism: rat
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Gene
485088 | STK11
Type: gene
Organism: dog, domestic
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Gene
468641 | STK11
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1341870 | Stk11
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
31636950 | J:330942
 
First Author: Chu Q
Year: 2019
Journal: Cell Discov
Title: STK11 is required for the normal program of ciliated cell differentiation in airways.
Volume: 5
Pages: 36
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Publication
25240456 | J:217896
 
First Author: Lai LP
Year: 2014
Journal: Bone
Title: Stk11 (Lkb1) deletion in the osteoblast lineage leads to high bone turnover, increased trabecular bone density and cortical porosity.
Volume: 69
Pages: 98-108
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Publication
25329316 | J:217430
First Author: Esteve-Puig R
Year: 2014
Journal: PLoS Genet
Title: A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation.
Volume: 10
Issue: 10
Pages: e1004721
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Publication
12226664 | J:78818
First Author: Bardeesy N
Year: 2002
Journal: Nature
Title: Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation.
Volume: 419
Issue: 6903
Pages: 162-7
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Publication
32779566 | J:303502
   
First Author: Levitan D
Year: 2020
Journal: Elife
Title: Deletion of Stk11 and Fos in mouse BLA projection neurons alters intrinsic excitability and impairs formation of long-term aversive memory.
Volume: 9
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Publication
18311138 | J:134476
First Author: Katajisto P
Year: 2008
Journal: Nat Genet
Title: LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis.
Volume: 40
Issue: 4
Pages: 455-9
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Publication
10642527 | J:60611
 
First Author: Collins SP
Year: 2000
Journal: Biochem J
Title: LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo.
Volume: 345 Pt 3
Pages: 673-80
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Publication
11297520 | J:175116
First Author: Sapkota GP
Year: 2001
Journal: J Biol Chem
Title: Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth.
Volume: 276
Issue: 22
Pages: 19469-82
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Publication
11853558 | J:175108
First Author: Sapkota GP
Year: 2002
Journal: Biochem J
Title: Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.
Volume: 362
Issue: Pt 2
Pages: 481-90
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Publication
12234250 | J:175207
First Author: Sapkota GP
Year: 2002
Journal: Biochem J
Title: Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.
Volume: 368
Issue: Pt 2
Pages: 507-16
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Publication
11956081 | J:76202
First Author: Miyoshi H
Year: 2002
Journal: Cancer Res
Title: Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice.
Volume: 62
Issue: 8
Pages: 2261-6
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Publication
18774945 | J:143943
First Author: Towler MC
Year: 2008
Journal: Biochem J
Title: A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis.
Volume: 416
Issue: 1
Pages: 1-14
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Publication
12218179 | J:79074
First Author: Rossi DJ
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis.
Volume: 99
Issue: 19
Pages: 12327-32
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Publication
15480979 | J:93361
First Author: Udd L
Year: 2004
Journal: Gastroenterology
Title: Suppression of Peutz-Jeghers polyposis by inhibition of cyclooxygenase-2.
Volume: 127
Issue: 4
Pages: 1030-7
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Publication
10381580 | J:56026
First Author: Luukko K
Year: 1999
Journal: Mech Dev
Title: Expression of LKB1 and PTEN tumor suppressor genes during mouse embryonic development.
Volume: 83
Issue: 1-2
Pages: 187-90
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Publication
18854309 | J:145786
First Author: Denison FC
Year: 2009
Journal: J Biol Chem
Title: Characterization of an alternative splice variant of LKB1.
Volume: 284
Issue: 1
Pages: 67-76
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Publication
11509733 | J:70892
First Author: Ylikorkala A
Year: 2001
Journal: Science
Title: Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice.
Volume: 293
Issue: 5533
Pages: 1323-6
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Publication
19541609 | J:150834
First Author: Shackelford DB
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome.
Volume: 106
Issue: 27
Pages: 11137-42
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Publication
12060709 | J:77213
First Author: Jishage K
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis.
Volume: 99
Issue: 13
Pages: 8903-8
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Publication
18172296 | J:131037
First Author: Gurumurthy S
Year: 2008
Journal: Cancer Res
Title: LKB1 deficiency sensitizes mice to carcinogen-induced tumorigenesis.
Volume: 68
Issue: 1
Pages: 55-63
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Publication
18245476 | J:131865
First Author: Contreras CM
Year: 2008
Journal: Cancer Res
Title: Loss of Lkb1 provokes highly invasive endometrial adenocarcinomas.
Volume: 68
Issue: 3
Pages: 759-66
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Publication
25256100 | J:316262
 
First Author: Pooya S
Year: 2014
Journal: Nat Commun
Title: The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism.
Volume: 5
Pages: 4993
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Publication
20541700 | J:160885
First Author: Carretero J
Year: 2010
Journal: Cancer Cell
Title: Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors.
Volume: 17
Issue: 6
Pages: 547-59
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Publication
28652249 | J:245582
First Author: Richer AL
Year: 2017
Journal: Cancer Res
Title: WEE1 Kinase Inhibitor AZD1775 Has Preclinical Efficacy in LKB1-Deficient Non-Small Cell Lung Cancer.
Volume: 77
Issue: 17
Pages: 4663-4672
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Publication
25071166 | J:213706
First Author: Amelio AL
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement.
Volume: 111
Issue: 32
Pages: E3260-8
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Publication
10400995 | J:56632
First Author: Smith DP
Year: 1999
Journal: Hum Mol Genet
Title: The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase.
Volume: 8
Issue: 8
Pages: 1479-85
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Publication
23597566 | J:197037
First Author: Xiao Z
Year: 2013
Journal: Cancer Cell
Title: The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.
Volume: 23
Issue: 4
Pages: 527-40
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Publication
18687677 | J:180573
First Author: Lan F
Year: 2008
Journal: J Biol Chem
Title: SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation.
Volume: 283
Issue: 41
Pages: 27628-35
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Publication
25588837 | J:223226
First Author: Krawchuk D
Year: 2015
Journal: J Cell Sci
Title: Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo.
Volume: 128
Issue: 5
Pages: 1011-22
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Publication
16308421 | J:104202
First Author: Shaw RJ
Year: 2005
Journal: Science
Title: The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.
Volume: 310
Issue: 5754
Pages: 1642-6
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Publication
18840652 | J:141132
First Author: Vaahtomeri K
Year: 2008
Journal: J Cell Sci
Title: Lkb1 is required for TGFbeta-mediated myofibroblast differentiation.
Volume: 121
Issue: Pt 21
Pages: 3531-40
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Publication
29202476 | J:258373
First Author: Ollila S
Year: 2018
Journal: J Clin Invest
Title: Stromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway.
Volume: 128
Issue: 1
Pages: 402-414
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Publication
17676035 | J:124682
First Author: Ji H
Year: 2007
Journal: Nature
Title: LKB1 modulates lung cancer differentiation and metastasis.
Volume: 448
Issue: 7155
Pages: 807-10
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Publication
17482548 | J:162066
First Author: Barnes AP
Year: 2007
Journal: Cell
Title: LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.
Volume: 129
Issue: 3
Pages: 549-63
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Publication
33236987 | J:305620
   
First Author: Khayati K
Year: 2020
Journal: Elife
Title: Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival.
Volume: 9
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Publication
23451056 | J:198481
First Author: Andrade-Vieira R
Year: 2013
Journal: PLoS One
Title: Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways.
Volume: 8
Issue: 2
Pages: e56567
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Publication
21266715 | J:185397
First Author: Jacob LS
Year: 2011
Journal: Sci Signal
Title: Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling.
Volume: 4
Issue: 157
Pages: ra4
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Publication
30049881 | J:323810
First Author: Poffenberger MC
Year: 2018
Journal: Science
Title: LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis.
Volume: 361
Issue: 6400
Pages: 406-411
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Publication
25584893 | J:218894
First Author: Damsky W
Year: 2015
Journal: Cancer Cell
Title: mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation.
Volume: 27
Issue: 1
Pages: 41-56
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Publication
35115536 | J:320666
First Author: Zhao Q
Year: 2022
Journal: Nat Commun
Title: Endothelial cell-specific expression of serine/threonine kinase 11 modulates dendritic cell differentiation.
Volume: 13
Issue: 1
Pages: 648
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Publication
28289208 | J:318881
First Author: George JW
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Specific deletion of LKB1/Stk11 in the Müllerian duct mesenchyme drives hyperplasia of the periurethral stroma and tumorigenesis in male mice.
Volume: 114
Issue: 13
Pages: 3445-3450
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Publication
30107230 | J:318527
 
First Author: Liang S
Year: 2018
Journal: Gene
Title: Identification of Skt11-regulated genes in chondrocytes by integrated bioinformatics analysis.
Volume: 677
Pages: 340-348
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Publication
31930988 | J:292470
First Author: Gao Y
Year: 2020
Journal: Gastroenterology
Title: LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate.
Volume: 158
Issue: 5
Pages: 1389-1401.e10
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UniProt Feature
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase STK11
Type: chain
End: 433
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Protein Coding Gene
MGP_CAROLIEiJ_G0015564 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017460 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017421 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017422 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017245 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1341870 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017876 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017217 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017323 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017317 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017343 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017917 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016593 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016872 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030977 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016382 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
11741830 | J:155212
First Author: Smith DP
Year: 2001
Journal: Hum Mol Genet
Title: LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1.
Volume: 10
Issue: 25
Pages: 2869-77
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Publication
26745759 | J:302720
First Author: Jiang ZZ
Year: 2016
Journal: Oncotarget
Title: LKB1 acts as a critical gatekeeper of ovarian primordial follicle pool.
Volume: 7
Issue: 5
Pages: 5738-53
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Publication
34995278 | J:322515
First Author: Fu F
Year: 2022
Journal: PLoS One
Title: Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models.
Volume: 17
Issue: 1
Pages: e0256512
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Publication
31328154 | J:293620
First Author: Radu AG
Year: 2019
Journal: Sci Adv
Title: LKB1 specifies neural crest cell fates through pyruvate-alanine cycling.
Volume: 5
Issue: 7
Pages: eaau5106
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Publication
29352002 | J:258423
First Author: Liu X
Year: 2018
Journal: J Immunol
Title: Intestinal Epithelial Cell-Derived LKB1 Suppresses Colitogenic Microbiota.
Volume: 200
Issue: 5
Pages: 1889-1900
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Publication
25190708 | J:217060
First Author: Zac-Varghese S
Year: 2014
Journal: Dis Model Mech
Title: The Peutz-Jeghers kinase LKB1 suppresses polyp growth from intestinal cells of a proglucagon-expressing lineage in mice.
Volume: 7
Issue: 11
Pages: 1275-86
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Publication
29022902 | J:273915
First Author: Kong F
Year: 2017
Journal: Cell Death Dis
Title: Differential regulation of spermatogenic process by Lkb1 isoforms in mouse testis.
Volume: 8
Issue: 10
Pages: e3121
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Publication
31091421 | J:293728
First Author: Zhou S
Year: 2019
Journal: FASEB J
Title: Inactivation of Lkb1 in postnatal chondrocytes leads to epiphyseal growth-plate abnormalities and promotes enchondroma-like formation.
Volume: 33
Issue: 8
Pages: 9476-9488
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Publication
24637557 | J:219306
First Author: Zhang W
Year: 2014
Journal: Circulation
Title: Endothelial cell-specific liver kinase B1 deletion causes endothelial dysfunction and hypertension in mice in vivo.
Volume: 129
Issue: 13
Pages: 1428-39
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Publication
20363912 | J:160753
First Author: Udd L
Year: 2010
Journal: Am J Pathol
Title: Impaired gastric gland differentiation in Peutz-Jeghers syndrome.
Volume: 176
Issue: 5
Pages: 2467-76
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Publication
23722652 | J:201841
First Author: Udd L
Year: 2013
Journal: Carcinogenesis
Title: N-methylnitrosourea aggravates gastrointestinal polyposis in Lkb1+/- mice.
Volume: 34
Issue: 10
Pages: 2409-14
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Publication
21341271 | J:170842
First Author: Lai C
Year: 2011
Journal: J Pathol
Title: Elevation of WNT5A expression in polyp formation in Lkb1+/- mice and Peutz-Jeghers syndrome.
Volume: 223
Issue: 5
Pages: 584-92
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Publication
19434632 | J:151905
First Author: Robinson J
Year: 2009
Journal: J Pathol
Title: Oral rapamycin reduces tumour burden and vascularization in Lkb1(+/-) mice.
Volume: 219
Issue: 1
Pages: 35-40
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Publication
18761009 | J:142963
First Author: Robinson J
Year: 2008
Journal: Exp Mol Pathol
Title: Osteogenic tumours in Lkb1-deficient mice.
Volume: 85
Issue: 3
Pages: 223-6
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Publication
27824128 | J:250199
 
First Author: Shan T
Year: 2016
Journal: Sci Rep
Title: Deletion of Lkb1 in adult mice results in body weight reduction and lethality.
Volume: 6
Pages: 36561
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Publication
27896618 | J:312421
First Author: Men Y
Year: 2016
Journal: Front Med
Title: Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice.
Volume: 10
Issue: 4
Pages: 481-489
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Publication
34341533 | J:317987
First Author: Pierce SE
Year: 2021
Journal: Nat Cell Biol
Title: LKB1 inactivation modulates chromatin accessibility to drive metastatic progression.
Volume: 23
Issue: 8
Pages: 915-924
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Publication
12183403 | J:78502
First Author: Nakau M
Year: 2002
Journal: Cancer Res
Title: Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice.
Volume: 62
Issue: 16
Pages: 4549-53
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Publication
28581518 | J:248101
First Author: Sengupta S
Year: 2017
Journal: Oncogene
Title: Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.
Volume: 36
Issue: 41
Pages: 5709-5721
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Publication
20354156 | J:162875
First Author: Sun G
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo.
Volume: 298
Issue: 6
Pages: E1261-73
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Publication
19147279 | J:147306
First Author: Wei C
Year: 2009
Journal: Cancer Lett
Title: Chemopreventive efficacy of rapamycin on Peutz-Jeghers syndrome in a mouse model.
Volume: 277
Issue: 2
Pages: 149-54
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Publication
18281551 | J:136016
First Author: Wei C
Year: 2008
Journal: Clin Cancer Res
Title: Suppression of Peutz-Jeghers polyposis by targeting mammalian target of rapamycin signaling.
Volume: 14
Issue: 4
Pages: 1167-71
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Publication
26054542 | J:290570
First Author: Han SH
Year: 2016
Journal: J Am Soc Nephrol
Title: Deletion of Lkb1 in Renal Tubular Epithelial Cells Leads to CKD by Altering Metabolism.
Volume: 27
Issue: 2
Pages: 439-53
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Publication
16966378 | J:114640
First Author: Koh HJ
Year: 2006
Journal: Mol Cell Biol
Title: Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3.
Volume: 26
Issue: 22
Pages: 8217-27
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Publication
31664743 | J:283817
First Author: Kalinin S
Year: 2020
Journal: Glia
Title: Liver kinase B1 depletion from astrocytes worsens disease in a mouse model of multiple sclerosis.
Volume: 68
Issue: 3
Pages: 600-616
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Publication
30566242 | J:273592
First Author: Charawi S
Year: 2019
Journal: J Pathol
Title: LKB1 signaling is activated in CTNNB1-mutated HCC and positively regulates β-catenin-dependent CTNNB1-mutated HCC.
Volume: 247
Issue: 4
Pages: 435-443
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Publication
16926377 | J:116973
First Author: Thomson DM
Year: 2007
Journal: Am J Physiol Endocrinol Metab
Title: Skeletal muscle and heart LKB1 deficiency causes decreased voluntary running and reduced muscle mitochondrial marker enzyme expression in mice.
Volume: 292
Issue: 1
Pages: E196-202
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