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Search results 1 to 85 out of 85 for Stx17

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Hits by Strain

Type Details Score
Gene
55014 | STX17
Type: gene
Organism: human
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Gene
252853 | Stx17
Type: gene
Organism: rat
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Gene
481630 | STX17
Type: gene
Organism: dog, domestic
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Gene
472994 | STX17
Type: gene
Organism: chimpanzee
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Gene
534304 | STX17
Type: gene
Organism: cattle
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Gene
420995 | STX17
Type: gene
Organism: chicken
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Gene
492808 | stx17
Type: gene
Organism: zebrafish
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Gene
714699 | STX17
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR028676 | STX17
Type: Family
Description: Syntaxin-17 (STX17) belongs to the syntaxin family, which is a group of the membrane integrated proteins participating in exocytosis. Syntaxins are associated with various intracellular membrane compartments and have been implicated in various physiological processes such as axonal growth and cell division [].STX17 is required to maintain the architecture of ER-Golgi intermediate compartment and Golgi []. STX17 is also involved in the fusion of autophagosomes with endosomes/lysosomes. Its unique C-terminal hairpin structure mediated by two tandem transmembrane domains is essential for its association with the autophagosomal membrane [, ].
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Protein Coding Gene
MGI:1914977 | Stx17
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23217709 | J:217983
First Author: Itakura E
Year: 2012
Journal: Cell
Title: The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes.
Volume: 151
Issue: 6
Pages: 1256-69
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Gene
441461 | STX17-DT
Type: gene
Organism: human
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Publication
21545355 | -
First Author: Muppirala M
Year: 2011
Journal: Biol Cell
Title: Syntaxin 17 cycles between the ER and ERGIC and is required to maintain the architecture of ERGIC and Golgi.
Volume: 103
Issue: 7
Pages: 333-50
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Publication
25686604 | -
First Author: Diao J
Year: 2015
Journal: Nature
Title: ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.
Volume: 520
Issue: 7548
Pages: 563-6
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Protein
B1AVI2
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
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Publication
18691641 | -
First Author: Pereira S
Year: 2008
Journal: Gene
Title: Nuclear localization of a novel human syntaxin 1B isoform.
Volume: 423
Issue: 2
Pages: 160-71
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Protein
Q9D0I4
Organism: Mus musculus/domesticus
Length: 301  
Fragment?: false
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Protein
Q9D614
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: false
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Publication
28504273 | J:249538
 
First Author: Arasaki K
Year: 2017
Journal: Nat Commun
Title: Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17.
Volume: 8
Pages: 15406
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Publication
36948287 | J:345305
 
First Author: Xu H
Year: 2023
Journal: Metabolism
Title: Syntaxin17 contributes to obesity cardiomyopathy through promoting mitochondrial Ca(2+) overload in a Parkin-MCUb-dependent manner.
Volume: 143
Pages: 155551
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Publication
35510944 | J:345512
 
First Author: Rong Y
Year: 2022
Journal: J Cell Biol
Title: STING controls energy stress-induced autophagy and energy metabolism via STX17.
Volume: 221
Issue: 7
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Publication
30681394 | J:284748
   
First Author: Xia Y
Year: 2019
Journal: Autophagy
Title: The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion.
Pages: 1-16
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Publication
27628032 | J:236240
First Author: Hubert V
Year: 2016
Journal: Biol Open
Title: LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes.
Volume: 5
Issue: 10
Pages: 1516-1529
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Protein Coding Gene
MGP_CAROLIEiJ_G0026000 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028271 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028230 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028180 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028250 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027971 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914977 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028691 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027410 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027937 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028087 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028186 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028078 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028726 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027135 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027488 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028336 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026963 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:657220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1842723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828524
Age: embryonic day 14.5
Image: euxassay_006759_10
Specimen Label: euxassay_006759_10
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:657220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1842723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828524
Age: embryonic day 14.5
Image: euxassay_006759_11
Specimen Label: euxassay_006759_11
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:657220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1842723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828524
Age: embryonic day 14.5
Image: euxassay_006759_12
Specimen Label: euxassay_006759_12
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:657220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1842723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828524
Age: embryonic day 14.5
Image: euxassay_006759_19
Specimen Label: euxassay_006759_19
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:657220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1842723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828524
Age: embryonic day 14.5
Image: euxassay_006759_20
Specimen Label: euxassay_006759_20
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:657220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1842723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828524
Age: embryonic day 14.5
Image: euxassay_006759_21
Specimen Label: euxassay_006759_21
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:657220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1842723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828524
Age: embryonic day 14.5
Image: euxassay_006759_22
Specimen Label: euxassay_006759_22
Detected: true
Specimen Num: 7
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
28933649 | -
First Author: Arasaki K
Year: 2017
Journal: Autophagy
Title: Legionella blocks autophagy by cleaving STX17 (syntaxin 17).
Volume: 13
Issue: 11
Pages: 2008-2009
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Protein Domain
IPR041000 | Serine_protease
Type: Family
Description: This family includes serine proteases such as L. pneumophila effector Lpg1137 []. Lpg1137, is a serine protease that targets the mitochondria-associated ER membrane (MAM) and degrades STX17 (syntaxin 17), a SNARE implicated in macroautophagy/autophagy as well as mitochondria dynamics and membrane trafficking in fed cells. Lpg1137 has a sequence (-Gly-Leu-Ser68-Gly-Gly-) that matches the consensus sequence for the active site of serine proteases (Gly-X-Ser-X-Gly/Ala, where X is any residue). It exhibits proteolytic activity toward STX17 in vitro, whereas an active site mutant in which Ser68 is replaced by Ala does not. Expressed Lpg1137 localizes to the MAM and mitochondria, in addition to the cytosol, and binds to STX17 [].
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Publication
30704899 | J:272052
First Author: Cheng X
Year: 2019
Journal: Mol Cell
Title: Pacer Is a Mediator of mTORC1 and GSK3-TIP60 Signaling in Regulation of Autophagosome Maturation and Lipid Metabolism.
Volume: 73
Issue: 4
Pages: 788-802.e7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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