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Search results 1 to 100 out of 334 for Stxbp1

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0.056s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Lammertse HCA
Year: 2020
Journal: Brain
Title: Homozygous STXBP1 variant causes encephalopathy and gain-of-function in synaptic transmission.
Volume: 143
Issue: 2
Pages: 441-451
Publication
First Author: Miyamoto H
Year: 2017
Journal: Hum Mol Genet
Title: Potentiation of excitatory synaptic transmission ameliorates aggression in mice with Stxbp1 haploinsufficiency.
Volume: 26
Issue: 24
Pages: 4961-4974
Publication    
First Author: Chen W
Year: 2020
Journal: Elife
Title: Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy.
Volume: 9
Publication
First Author: Miyamoto H
Year: 2019
Journal: Nat Commun
Title: Impaired cortico-striatal excitatory transmission triggers epilepsy.
Volume: 10
Issue: 1
Pages: 1917
Publication  
First Author: Orock A
Year: 2018
Journal: Mol Cell Neurosci
Title: Munc18-1 haploinsufficiency impairs learning and memory by reduced synaptic vesicular release in a model of Ohtahara syndrome.
Volume: 88
Pages: 33-42
Publication
First Author: Wu Z
Year: 2013
Journal: PLoS One
Title: Syntaxin binding protein 1 is not required for allergic inflammation via IgE-mediated mast cell activation.
Volume: 8
Issue: 3
Pages: e58560
Publication  
First Author: Campbell JR
Year: 2020
Journal: Endocrinology
Title: Essential Role of Syntaxin-Binding Protein-1 in the Regulation of Glucagon-Like Peptide-1 Secretion.
Volume: 161
Issue: 5
Publication
First Author: Fehr C
Year: 2005
Journal: Alcohol Clin Exp Res
Title: The syntaxin binding protein 1 gene (Stxbp1) is a candidate for an ethanol preference drinking locus on mouse chromosome 2.
Volume: 29
Issue: 5
Pages: 708-20
Publication  
First Author: Zhang K
Year: 2021
Journal: Mol Cell Endocrinol
Title: CASK, APBA1, and STXBP1 collaborate during insulin secretion.
Volume: 520
Pages: 111076
Publication  
First Author: Taura Y
Year: 2023
Journal: Neuroscience
Title: Myosin Va, a Novel Interaction Partner of STXBP1, Is Required to Transport Syntaxin1A to the Plasma Membrane.
Volume: 524
Pages: 256-268
Allele
Name: syntaxin binding protein 1; targeted mutation 1.1, Benjamin Prosser
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Gotoh K
Year: 1998
Journal: J Biol Chem
Title: Genomic structure of MUNC18-1 protein, which is involved in docking and fusion of synaptic vesicles in brain.
Volume: 273
Issue: 34
Pages: 21642-7
Publication
First Author: Halachmi N
Year: 1996
Journal: J Neurochem
Title: The Sec1 family: a novel family of proteins involved in synaptic transmission and general secretion.
Volume: 66
Issue: 3
Pages: 889-97
Publication
First Author: Oh E
Year: 2012
Journal: J Biol Chem
Title: Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms.
Volume: 287
Issue: 31
Pages: 25821-33
Publication
First Author: Park S
Year: 2017
Journal: J Neurosci
Title: UNC-18 and Tomosyn Antagonistically Control Synaptic Vesicle Priming Downstream of UNC-13 in Caenorhabditis elegans.
Volume: 37
Issue: 36
Pages: 8797-8815
Publication
First Author: Nicol X
Year: 2007
Journal: Nat Neurosci
Title: cAMP oscillations and retinal activity are permissive for ephrin signaling during the establishment of the retinotopic map.
Volume: 10
Issue: 3
Pages: 340-7
Publication
First Author: Deák F
Year: 2009
Journal: J Cell Biol
Title: Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming.
Volume: 184
Issue: 5
Pages: 751-64
Publication
First Author: Manent JB
Year: 2005
Journal: J Neurosci
Title: A noncanonical release of GABA and glutamate modulates neuronal migration.
Volume: 25
Issue: 19
Pages: 4755-65
Publication    
First Author: Miyazaki T
Year: 2021
Journal: Elife
Title: Excitatory and inhibitory receptors utilize distinct post- and trans-synaptic mechanisms in vivo.
Volume: 10
Publication
First Author: Voets T
Year: 2001
Journal: Neuron
Title: Munc18-1 promotes large dense-core vesicle docking.
Volume: 31
Issue: 4
Pages: 581-91
Publication
First Author: Meijer M
Year: 2018
Journal: EMBO J
Title: Tyrosine phosphorylation of Munc18-1 inhibits synaptic transmission by preventing SNARE assembly.
Volume: 37
Issue: 2
Pages: 300-320
Publication
First Author: van Berkel AA
Year: 2021
Journal: J Neurochem
Title: Loss of MUNC18-1 leads to retrograde transport defects in neurons.
Volume: 157
Issue: 3
Pages: 450-466
Publication
First Author: Wierda KD
Year: 2007
Journal: Neuron
Title: Interdependence of PKC-dependent and PKC-independent pathways for presynaptic plasticity.
Volume: 54
Issue: 2
Pages: 275-90
Publication
First Author: Toonen RF
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Munc18-1 expression levels control synapse recovery by regulating readily releasable pool size.
Volume: 103
Issue: 48
Pages: 18332-7
Publication
First Author: Toonen RF
Year: 2003
Journal: Biochem Soc Trans
Title: Role of Munc18-1 in synaptic vesicle and large dense-core vesicle secretion.
Volume: 31
Issue: Pt 4
Pages: 848-50
Publication
First Author: Toonen RF
Year: 2006
Journal: EMBO J
Title: Dissecting docking and tethering of secretory vesicles at the target membrane.
Volume: 25
Issue: 16
Pages: 3725-37
Publication
First Author: Heeroma JH
Year: 2004
Journal: Eur J Neurosci
Title: Trophic support delays but does not prevent cell-intrinsic degeneration of neurons deficient for munc18-1.
Volume: 20
Issue: 3
Pages: 623-34
Publication
First Author: Cijsouw T
Year: 2014
Journal: J Cell Biol
Title: Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner.
Volume: 204
Issue: 5
Pages: 759-75
Publication
First Author: Abramov D
Year: 2021
Journal: EMBO Mol Med
Title: Targeted stabilization of Munc18-1 function via pharmacological chaperones.
Volume: 13
Issue: 1
Pages: e12354
Publication
First Author: Guiberson NGL
Year: 2018
Journal: Nat Commun
Title: Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones.
Volume: 9
Issue: 1
Pages: 3986
GXD Expression    
Probe: MGI:3053113
Assay Type: Western blot
Annotation Date: 2004-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3053155
Age: postnatal
Image: 3
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3053113
Assay Type: Western blot
Annotation Date: 2004-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3053155
Age: postnatal
Image: 3
Specimen Label: J1-/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3053113
Assay Type: Western blot
Annotation Date: 2004-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3053155
Age: postnatal
Image: 3
Specimen Label: J2-/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3053113
Assay Type: Western blot
Annotation Date: 2004-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3053155
Age: postnatal
Image: 3
Specimen Label: J1-/- J2-/+
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3053113
Assay Type: Western blot
Annotation Date: 2004-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3053158
Age: embryonic day 18.5
Image: 3
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3053113
Assay Type: Western blot
Annotation Date: 2004-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3053158
Age: embryonic day 18.5
Image: 3
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3053113
Assay Type: Western blot
Annotation Date: 2004-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3053158
Age: embryonic day 18.5
Image: 3
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3652729
Assay Type: Western blot
Annotation Date: 2006-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3652754
Age: embryonic day 19.0
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3652729
Assay Type: Western blot
Annotation Date: 2006-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3652754
Age: embryonic day 19.0
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3053113
Assay Type: Western blot
Annotation Date: 2005-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:3576316
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression        
Probe: MGI:3053113
Assay Type: Western blot
Annotation Date: 2005-05-05
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:3576316
Age: embryonic day 18.5
Specimen Label: -/-
Specimen Num: 2
GXD Expression    
Probe: MGI:6437135
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437201
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6437135
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437201
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6437135
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437201
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6437135
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437204
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6437135
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437204
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6437135
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437204
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437208
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437208
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437208
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437209
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437209
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:6437209
Age: embryonic day 17.5
Image: 1 S1
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: aCTX
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: aCTX
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: pCTX
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: pCTX
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: HIP
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: HIP
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: TH+HY
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: TH+HY
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: TH+HY
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: TH+HY
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: STR
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: STR
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: CB
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: CB
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: OLF
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: OLF
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691628
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: MB+HB
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: MB+HB
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:6437133
Assay Type: Western blot
Annotation Date: 2020-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691628
Stage: TS28
Assay Id: MGI:6437210
Age: postnatal month 3
Image: 1
Specimen Label: MB+HB
Detected: true
Specimen Num: 16