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Search results 1 to 100 out of 260 for Synj2

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0.035s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: Synaptojanin-2 is a ubiquitously expressed central regulatory enzyme in the phosphoinositide-signaling cascade []. As a novel Rac1 effector regulating an early step of clathrin-mediated endocytosis, synaptojanin-2 acts as a polyphosphoinositide phosphatase, directly and specifically interacting with Rac1 in a GTP-dependent manner. It mediates the inhibitory effect of Rac1 on endocytosis and plays an important role in the Rac1-mediated control of cell growth []. Synaptojanin-2 shows high sequence homology to the N-terminal Sac1p homology domain [], the central inositol 5-phosphatase domain, and the putative RNA recognition motif (RRM) of synaptojanin-1, but differs in the proline-rich region.
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Schimenti JC
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Mutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortion.
Volume: 102
Issue: 9
Pages: 3342-7
Protein
Organism: Mus musculus
Length: 1434  
Fragment?: false
Protein
Organism: Mus musculus
Length: 725  
Fragment?: true
Protein
Organism: Mus musculus
Length: 384  
Fragment?: true
Protein
Organism: Mus musculus
Length: 60  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1479  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1394  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1118  
Fragment?: false
Protein
Organism: Mus musculus
Length: 535  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1118  
Fragment?: false
Protein
Organism: Mus musculus
Length: 660  
Fragment?: true
Protein
Organism: Mus musculus
Length: 84  
Fragment?: false
Publication  
First Author: Singer-Kr├╝ger B
Year: 1998
Journal: J Cell Sci
Title: Synaptojanin family members are implicated in endocytic membrane traffic in yeast.
Volume: 111 ( Pt 22)
Pages: 3347-56
Publication
First Author: Malecz N
Year: 2000
Journal: Curr Biol
Title: Synaptojanin 2, a novel Rac1 effector that regulates clathrin-mediated endocytosis.
Volume: 10
Issue: 21
Pages: 1383-6
Publication
First Author: Rusk N
Year: 2003
Journal: Curr Biol
Title: Synaptojanin 2 functions at an early step of clathrin-mediated endocytosis.
Volume: 13
Issue: 8
Pages: 659-63
Publication
First Author: Manji SS
Year: 2011
Journal: PLoS One
Title: A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart.
Volume: 6
Issue: 3
Pages: e17607
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Seet LF
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Molecular cloning of multiple isoforms of synaptojanin 2 and assignment of the gene to mouse chromosome 17A2-3.1.
Volume: 247
Issue: 1
Pages: 116-22
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2653280
Age: postnatal adult
Image: 4
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2653280
Age: postnatal adult
Image: 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2653278
Assay Type: Northern blot
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2653279
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3615221
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616623
Age: postnatal day 0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3615221
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616623
Age: embryonic day 13.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653285
Age: postnatal adult
Image: 6
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653285
Age: postnatal day 20
Image: 6
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653285
Age: postnatal day 17
Image: 6
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653285
Age: postnatal day 15
Image: 6
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653285
Age: postnatal day 13
Image: 6
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653285
Age: postnatal day 11
Image: 6
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653285
Age: postnatal day 9
Image: 6
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653285
Age: postnatal day 7
Image: 6
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653285
Age: postnatal day 5
Image: 6
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2653285
Age: postnatal day 3
Image: 6
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2653285
Age: postnatal day 1
Image: 6
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:2653285
Age: embryonic day 18.0
Image: 6
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653283
Age: postnatal adult
Image: 6
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653283
Age: postnatal day 20
Image: 6
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653283
Age: postnatal day 17
Image: 6
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653283
Age: postnatal day 15
Image: 6
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653283
Age: postnatal day 13
Image: 6
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653283
Age: postnatal day 11
Image: 6
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653283
Age: postnatal day 9
Image: 6
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653283
Age: postnatal day 7
Image: 6
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653283
Age: postnatal day 5
Image: 6
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2653283
Age: postnatal day 3
Image: 6
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2653283
Age: postnatal day 1
Image: 6
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:2653283
Age: embryonic day 18.0
Image: 6
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653282
Age: postnatal adult
Image: 6
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653282
Age: postnatal day 20
Image: 6
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653282
Age: postnatal day 17
Image: 6
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653282
Age: postnatal day 15
Image: 6
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653282
Age: postnatal day 13
Image: 6
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653282
Age: postnatal day 11
Image: 6
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653282
Age: postnatal day 9
Image: 6
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653282
Age: postnatal day 7
Image: 6
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653282
Age: postnatal day 5
Image: 6
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2653282
Age: postnatal day 3
Image: 6
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2653282
Age: postnatal day 1
Image: 6
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:2653282
Age: embryonic day 18.0
Image: 6
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653280
Age: postnatal adult
Image: 4
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2653278
Assay Type: Northern blot
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2653279
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2653280
Age: postnatal adult
Image: 4
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2653280
Age: postnatal adult
Image: 4
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2653280
Age: postnatal adult
Image: 4
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2653280
Age: postnatal adult
Image: 4
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2653228
Assay Type: RT-PCR
Annotation Date: 2003-04-02
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2653280
Age: postnatal adult
Image: 4
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:4416155
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876922
Stage: TS22
Assay Id: MGI:5421820
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4416155
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753622
Stage: TS22
Assay Id: MGI:5421820
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3615993
Assay Type: RNA in situ
Annotation Date: 2006-03-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753627
Stage: TS27
Assay Id: MGI:3618087
Age: postnatal day 0
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:4416155
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:5421820
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4416155
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274322
Stage: TS22
Assay Id: MGI:5421820
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4416155
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672722
Stage: TS22
Assay Id: MGI:5421820
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4416155
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647022
Stage: TS22
Assay Id: MGI:5421820
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4416155
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:5421820
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4416155
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3272922
Stage: TS22
Assay Id: MGI:5421820
Age: embryonic day 14.5
Note: Expression was not detected in the skeleton (limbs, shoulder, hip).
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4416155
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1781522
Stage: TS22
Assay Id: MGI:5421820
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4416155
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828559
Age: embryonic day 14.5
Image: euxassay_012284_17
Detected: true
Specimen Num: 11