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Search results 1 to 100 out of 825 for Syp

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Synaptophysin interacts with the essential synaptic vesicle protein synaptobrevin, suggesting a role for synaptophysin in the control of exocytosis [, , ]. Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in neurons []. It has been shown to involved in the regulation of short-term and long-term synaptic plasticity [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Kwon SE
Year: 2011
Journal: Neuron
Title: Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons.
Volume: 70
Issue: 5
Pages: 847-54
Publication
First Author: Janz R
Year: 1999
Journal: Neuron
Title: Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I.
Volume: 24
Issue: 3
Pages: 687-700
Protein
Organism: Mus musculus/domesticus
Length: 314  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 227  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 165  
Fragment?: true
Publication
First Author: Edelmann L
Year: 1995
Journal: EMBO J
Title: Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.
Volume: 14
Issue: 2
Pages: 224-31
Publication
First Author: Becher A
Year: 1999
Journal: J Neurosci
Title: The synaptophysin-synaptobrevin complex: a hallmark of synaptic vesicle maturation.
Volume: 19
Issue: 6
Pages: 1922-31
Publication
First Author: Alder J
Year: 1992
Journal: Neuron
Title: Antibodies to synaptophysin interfere with transmitter secretion at neuromuscular synapses.
Volume: 9
Issue: 4
Pages: 759-68
GXD Expression
Probe: MGI:6478211
Assay Type: RNA in situ
Annotation Date: 2020-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6478276
Age: postnatal month 5.5-7
Image: 6A Trib3-/-
Note: The expression pattern of Syp in the Trib3-/- was similar to Trib3+/+.
Specimen Label: 6A Trib3-/-
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6478211
Assay Type: RNA in situ
Annotation Date: 2020-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6478276
Age: postnatal month 5.5-7
Image: 6B Trib3-/-
Note: The expression pattern of Syp in the Trib3-/- was similar to Trib3+/+.
Specimen Label: 6B Trib3-/-
Detected: true
Specimen Num: 4
Allele
Name: protein tyrosine phosphatase, non-receptor type 11; targeted mutation 1, Daniel U Rabin
Allele Type: Targeted
Attribute String: Null/knockout
GXD Expression  
Probe: MGI:3579864
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6416301
Age: embryonic day 18.5
Note: Expressed in nerve terminals, similar level as in the wild type. But the synapse number (coexpressed Syp and Chrnb2/b4) was decreased by 40%.
Specimen Label: 2a AGD-/-
Detected: true
Specimen Num: 5
Publication
First Author: McMahon HT
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release.
Volume: 93
Issue: 10
Pages: 4760-4
Publication
First Author: Ozçelik T
Year: 1990
Journal: Am J Hum Genet
Title: Synaptophysin: structure of the human gene and assignment to the X chromosome in man and mouse.
Volume: 47
Issue: 3
Pages: 551-61
Publication
First Author: Chang CW
Year: 2021
Journal: J Neurosci
Title: Synaptophysin Regulates Fusion Pores and Exocytosis Mode in Chromaffin Cells.
Volume: 41
Issue: 16
Pages: 3563-3578
Publication
First Author: Felkl M
Year: 2008
Journal: Neuroscience
Title: Interaction assays in yeast and cultured cells confirm known and identify novel partners of the synaptic vesicle protein synaptophysin.
Volume: 156
Issue: 2
Pages: 344-52
Publication
First Author: Tauchi T
Year: 1994
Journal: J Biol Chem
Title: The ubiquitously expressed Syp phosphatase interacts with c-kit and Grb2 in hematopoietic cells.
Volume: 269
Issue: 40
Pages: 25206-11
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Gaitanou M
Year: 1997
Journal: J Neurosci Res
Title: Purification and cDNA cloning of mouse BM89 antigen shows that it is identical with the synaptic vesicle protein synaptophysin.
Volume: 48
Issue: 6
Pages: 507-14
Publication
First Author: King DL
Year: 2002
Journal: Brain Res
Title: Maintained synaptophysin immunoreactivity in Tg2576 transgenic mice during aging: correlations with cognitive impairment.
Volume: 926
Issue: 1-2
Pages: 58-68
Publication
First Author: Bai L
Year: 2006
Journal: Brain Res
Title: Transcriptome comparison of murine wild-type and synaptophysin-deficient retina reveals complete identity.
Volume: 1081
Issue: 1
Pages: 53-8
Publication
First Author: Schmitt U
Year: 2009
Journal: Neuroscience
Title: Detection of behavioral alterations and learning deficits in mice lacking synaptophysin.
Volume: 162
Issue: 2
Pages: 234-43
Publication
First Author: Spiwoks-Becker I
Year: 2001
Journal: Neuroscience
Title: Synaptic vesicle alterations in rod photoreceptors of synaptophysin-deficient mice.
Volume: 107
Issue: 1
Pages: 127-42
Publication  
First Author: Harper CB
Year: 2017
Journal: Neurobiol Dis
Title: Altered synaptobrevin-II trafficking in neurons expressing a synaptophysin mutation associated with a severe neurodevelopmental disorder.
Volume: 108
Pages: 298-306
Publication
First Author: Praznikar ZJ
Year: 2008
Journal: Biochim Biophys Acta
Title: A presynaptically toxic secreted phospholipase A2 is internalized into motoneuron-like cells where it is rapidly translocated into the cytosol.
Volume: 1783
Issue: 6
Pages: 1129-39
Publication
First Author: Pyeon HJ
Year: 2012
Journal: Anat Cell Biol
Title: Differential expression levels of synaptophysin through developmental stages in hippocampal region of mouse brain.
Volume: 45
Issue: 2
Pages: 97-102
GXD Expression      
Probe: MGI:2667807
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:2667821
Age: embryonic day 13.0
Specimen Label: ED 13
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2667807
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:2667821
Age: embryonic day 14.0
Specimen Label: ED 14
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:2667807
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:2667821
Age: embryonic day 15.0
Specimen Label: ED 15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2667807
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:2667821
Age: embryonic day 17.0
Specimen Label: ED 17
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2667807
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:2667821
Age: embryonic day 18.0
Specimen Label: ED 18
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2667807
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2667821
Age: postnatal newborn
Specimen Label: New born
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2667807
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2667821
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2667813
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:2667831
Age: embryonic day 13.0
Specimen Label: ED 13
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2667813
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:2667831
Age: embryonic day 14.0
Specimen Label: ED 14
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:2667813
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:2667831
Age: embryonic day 15.0
Specimen Label: ED 15
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2667813
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:2667831
Age: embryonic day 17.0
Specimen Label: ED 17
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2667813
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:2667831
Age: embryonic day 18.0
Specimen Label: ED 18
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2667813
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2667831
Age: postnatal newborn
Specimen Label: New born
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2667813
Assay Type: Western blot
Annotation Date: 2003-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2667831
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3028116
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:3028211
Age: embryonic day 10.0
Image: 2
Specimen Label: E10 Whole
Specimen Num: 1
GXD Expression      
Probe: MGI:3028116
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:3028211
Age: embryonic day 14.0
Image: 2
Specimen Label: E14 Whole
Specimen Num: 2
GXD Expression      
Probe: MGI:3028116
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689420
Stage: TS20
Assay Id: MGI:3028211
Age: embryonic day 12.0
Image: 2
Specimen Label: E12 Brain
Specimen Num: 3
GXD Expression      
Probe: MGI:3028116
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:3028211
Age: embryonic day 14.0
Image: 2
Specimen Label: E14 Brain
Specimen Num: 4
GXD Expression    
Probe: MGI:3028116
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3028211
Age: embryonic day 18.0
Image: 2
Specimen Label: E18 Brain
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3028116
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3028211
Age: postnatal day 0
Image: 2
Specimen Label: P0 Brain
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3028116
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3028211
Age: postnatal day 7
Image: 2
Specimen Label: P7 Brain
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3028116
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3028211
Age: postnatal day 25
Image: 2
Specimen Label: P25 Brain
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3028116
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3028211
Age: postnatal adult
Image: 2
Specimen Label: Adult Brain
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3621917
Assay Type: Western blot
Annotation Date: 2006-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3621981
Age: postnatal
Specimen Label: wt
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3621917
Assay Type: Western blot
Annotation Date: 2006-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3621981
Age: postnatal
Specimen Label: ceb ko
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3621917
Assay Type: Western blot
Annotation Date: 2006-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3621981
Age: postnatal
Specimen Label: dko
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4948536
Assay Type: Western blot
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:3641134
Age: embryonic day 18.0
Image: 6
Specimen Label: C
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3701250
Assay Type: Western blot
Annotation Date: 2007-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3701273
Age: embryonic day 18.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3701250
Assay Type: Western blot
Annotation Date: 2007-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3701273
Age: embryonic day 18.5
Image: 1
Specimen Label: -/-
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3701250
Assay Type: Western blot
Annotation Date: 2007-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3701273
Age: embryonic day 18.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:4948537
Assay Type: Western blot
Annotation Date: 2008-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:3820075
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4948537
Assay Type: Western blot
Annotation Date: 2008-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3820075
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4948537
Assay Type: Western blot
Annotation Date: 2008-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3820075
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4948537
Assay Type: Western blot
Annotation Date: 2008-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3820075
Age: postnatal day 14
Specimen Label: P14
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4948537
Assay Type: Western blot
Annotation Date: 2008-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3820075
Age: postnatal month 1
Specimen Label: 1 mo
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4948537
Assay Type: Western blot
Annotation Date: 2008-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3820075
Age: postnatal month 2
Specimen Label: 2 mo
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4948537
Assay Type: Western blot
Annotation Date: 2008-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3820075
Age: postnatal month 6
Specimen Label: 6 mo
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:4948537
Assay Type: Western blot
Annotation Date: 2008-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3820075
Age: postnatal year 1
Specimen Label: 1 yr
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:2667813
Assay Type: Western blot
Annotation Date: 2015-05-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5637354
Age: postnatal
Specimen Label: H
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5787790
Assay Type: Western blot
Annotation Date: 2016-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:5788316
Age: embryonic day 18.5
Specimen Label: wt/wt
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5787790
Assay Type: Western blot
Annotation Date: 2016-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:5788316
Age: embryonic day 18.5
Specimen Label: wt/del
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5787790
Assay Type: Western blot
Annotation Date: 2016-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757726
Stage: TS26
Assay Id: MGI:5788316
Age: embryonic day 18.5
Specimen Label: del/del
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5812229
Assay Type: Western blot
Annotation Date: 2016-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5812273
Age: postnatal month 3-6
Image: 1
Specimen Label: total
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5911346
Assay Type: Western blot
Annotation Date: 2017-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5911465
Age: postnatal month 4
Specimen Label: WT 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5911346
Assay Type: Western blot
Annotation Date: 2017-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:5911465
Age: postnatal month 4
Specimen Label: KO 1
Detected: true
Specimen Num: 2