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Search results 1 to 69 out of 69 for Syt12

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Hits by Strain

Hits by Category

Type Details Score
Gene
91683 | SYT12
Type: gene
Organism: human
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Gene
466682 | SYT12
Type: gene
Organism: chimpanzee
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Gene
536820 | SYT12
Type: gene
Organism: cattle
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Gene
422998 | SYT12
Type: gene
Organism: chicken
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Gene
566397 | syt12
Type: gene
Organism: zebrafish
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Gene
721773 | SYT12
Type: gene
Organism: macaque, rhesus
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Gene
100496899 | syt12
Type: gene
Organism: frog, western clawed
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Gene
191595 | Syt12
Type: gene
Organism: rat
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Gene
483703 | SYT12
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:2159601 | Syt12
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR030537 | SYT12
Type: Family
Description: Synaptotagmin-12 (Syt12) belongs to the synaptotagmin family, which is a group of membrane-trafficking proteins that contain two C-terminal C2 domains (known as C2A and C2B domains). Most of the synaptotagmins have a unique N-terminal domain that is involved in membrane anchoring or specific ligand binding. Mammals contain 16 synaptotagmins; eight of these bind Ca2+ via their C2-domains (Syt1-Syt3, Syt5-7, Syt9, and Syt10), whereas the other eight, including Syt12, do not [].Syt12 colocalises with and binds Syt1 on synaptic vesicles, but regulates spontaneous release independently from Syt1. Syt12 is phosphorylated by cAMP-dependent protein kinase A (PKA) at a single site, and mutation of this site blocks the effect of Syt12 on spontaneous release []. Syt12 is not essential for basal synaptic transmission, but is required for cAMP-dependent mossy fibre long-term potentiation (LTP), a presynaptic form of long-term plasticity that is induced by PKA activation [].
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Publication
23739973 | J:198642
First Author: Kaeser-Woo YJ
Year: 2013
Journal: J Neurosci
Title: Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP.
Volume: 33
Issue: 23
Pages: 9769-80
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Publication
17190793 | J:276382
First Author: Maximov A
Year: 2007
Journal: J Cell Biol
Title: Synaptotagmin-12, a synaptic vesicle phosphoprotein that modulates spontaneous neurotransmitter release.
Volume: 176
Issue: 1
Pages: 113-24
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Publication
20561775 | -
First Author: Pang ZP
Year: 2010
Journal: Curr Opin Cell Biol
Title: Cell biology of Ca2+-triggered exocytosis.
Volume: 22
Issue: 4
Pages: 496-505
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Protein
Q920N7
Organism: Mus musculus/domesticus
Length: 421  
Fragment?: false
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Protein
Q14AG7
Organism: Mus musculus/domesticus
Length: 421  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0022507 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024664 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024630 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024603 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024630 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024398 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2159601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025078 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023870 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0024369 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024497 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024464 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024583 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024494 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023616 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023932 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014003 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023421 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:1059698
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1857523
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4828566
Age: embryonic day 14.5
Image: euxassay_000226_13
Specimen Label: euxassay_000226_13
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1059698
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1857523
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4828566
Age: embryonic day 14.5
Image: euxassay_000226_14
Specimen Label: euxassay_000226_14
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1059698
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1857523
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4828566
Age: embryonic day 14.5
Image: euxassay_000226_15
Specimen Label: euxassay_000226_15
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:1059698
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1842623
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828566
Age: embryonic day 14.5
Image: euxassay_000226_11
Specimen Label: euxassay_000226_11
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1059698
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1842623
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828566
Age: embryonic day 14.5
Image: euxassay_000226_12
Specimen Label: euxassay_000226_12
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1059698
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1842623
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828566
Age: embryonic day 14.5
Image: euxassay_000226_18
Specimen Label: euxassay_000226_18
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:1059698
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1842623
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828566
Age: embryonic day 14.5
Image: euxassay_000226_19
Specimen Label: euxassay_000226_19
Detected: true
Specimen Num: 7
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Publication
- | J:75061
   
First Author: Fukuda M
Year: 2001
Journal: GenBank Submission
Title: Mus musculus Syt XII mRNA for synaptotagmin XII, complete cds
Pages: AB062804
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Publication
- | J:178819
     
First Author: Sudhof TC
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/03/10
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Publication
16407767 | J:104925
First Author: Fukuda M
Year: 2006
Journal: Neuroreport
Title: Distinct developmental expression of synaptotagmin I and IX in the mouse brain.
Volume: 17
Issue: 2
Pages: 179-82
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Allele
Syt12<tm1.1Sud> | MGI:4940391
 
Name: synaptotagmin XII; targeted mutation 1.1, Thomas C Sudhof
Allele Type: Targeted
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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