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Search results 1 to 86 out of 86 for Sytl1

0.043s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Synaptotagmin-like protein 1 (Slp1/Jfc1) acts as a Rab27a effector and plays a role in vesicle trafficking [, ]. Through its interaction with Rab27a, Slp1 also contributes to secretory lysosome exocytosis from cytotoxic T lymphocytes. Slp1 (and Slp2) may form part of a docking complex, capturing secretory lysosomes at the immunological synapse [].Slp1 possesses two C2 domains in tandem, domain C2A showing homology with the C2B domain of synaptotagmins [].
Publication
First Author: Johnson JL
Year: 2012
Journal: Mol Biol Cell
Title: Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein.
Volume: 23
Issue: 10
Pages: 1902-16
Publication
First Author: Holt O
Year: 2008
Journal: Traffic
Title: Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse.
Volume: 9
Issue: 4
Pages: 446-57
Protein
Organism: Mus musculus/domesticus
Length: 567  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 503  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 590  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 568  
Fragment?: false
Publication
First Author: Hokanson DE
Year: 2012
Journal: Mol Biol Cell
Title: EPI64 interacts with Slp1/JFC1 to coordinate Rab8a and Arf6 membrane trafficking.
Volume: 23
Issue: 4
Pages: 701-15
Publication
First Author: McAdara Berkowitz JK
Year: 2001
Journal: J Biol Chem
Title: JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase.
Volume: 276
Issue: 22
Pages: 18855-62
Publication
First Author: Yokoyama T
Year: 2016
Journal: J Clin Invest
Title: MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis.
Volume: 126
Issue: 5
Pages: 1664-78
Publication
First Author: Kurz AR
Year: 2016
Journal: J Clin Invest
Title: MST1-dependent vesicle trafficking regulates neutrophil transmigration through the vascular basement membrane.
Volume: 126
Issue: 11
Pages: 4125-4139
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Skeletal Muscle
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Testis
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:1933796
Age: embryonic day 7.0
Specimen Label: E7
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:1933796
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:1933796
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:1933796
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 12
Publication
First Author: Wang H
Year: 2013
Journal: Mol Biol Cell
Title: The Rab27a effector exophilin7 promotes fusion of secretory granules that have not been docked to the plasma membrane.
Volume: 24
Issue: 3
Pages: 319-30
Publication
First Author: Ramadass M
Year: 2019
Journal: J Leukoc Biol
Title: The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration.
Volume: 105
Issue: 6
Pages: 1209-1224
Publication
First Author: Saegusa C
Year: 2008
Journal: Arch Biochem Biophys
Title: Expression of Rab27B-binding protein Slp1 in pancreatic acinar cells and its involvement in amylase secretion.
Volume: 475
Issue: 1
Pages: 87-92
Publication
First Author: Fukuda M
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins.
Volume: 281
Issue: 5
Pages: 1226-33
Publication
First Author: Kuroda TS
Year: 2002
Journal: J Biol Chem
Title: The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.
Volume: 277
Issue: 11
Pages: 9212-8
Publication
First Author: Fukuda M
Year: 2003
Journal: J Biol Chem
Title: Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.
Volume: 278
Issue: 17
Pages: 15390-6
Publication
First Author: Adissu HA
Year: 2014
Journal: Dis Model Mech
Title: Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.
Volume: 7
Issue: 5
Pages: 515-24
Publication
First Author: Quina LA
Year: 2009
Journal: J Neurosci
Title: Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.
Volume: 29
Issue: 45
Pages: 14309-22
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform