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Search results 1 to 89 out of 89 for Sytl1

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
84958 | SYTL1
Type: gene
Organism: human
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Gene
448459 | sytl1
Type: gene
Organism: frog, western clawed
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Gene
297872 | Sytl1
Type: gene
Organism: rat
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Gene
487346 | SYTL1
Type: gene
Organism: dog, domestic
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Gene
456673 | SYTL1
Type: gene
Organism: chimpanzee
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Gene
527641 | SYTL1
Type: gene
Organism: cattle
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Gene
771987 | SYTL1
Type: gene
Organism: chicken
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Gene
777759 | sytl1
Type: gene
Organism: zebrafish
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Gene
715833 | SYTL1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1933365 | Sytl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR028378 | Sytl1
Type: Family
Description: Synaptotagmin-like protein 1 (Slp1/Jfc1) acts as a Rab27a effector and plays a role in vesicle trafficking [, ]. Through its interaction with Rab27a, Slp1 also contributes to secretory lysosome exocytosis from cytotoxic T lymphocytes. Slp1 (and Slp2) may form part of a docking complex, capturing secretory lysosomes at the immunological synapse [].Slp1 possesses two C2 domains in tandem, domain C2A showing homology with the C2B domain of synaptotagmins [].
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Publication
22438581 | J:197810
First Author: Johnson JL
Year: 2012
Journal: Mol Biol Cell
Title: Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein.
Volume: 23
Issue: 10
Pages: 1902-16
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Publication
18266782 | J:150917
First Author: Holt O
Year: 2008
Journal: Traffic
Title: Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse.
Volume: 9
Issue: 4
Pages: 446-57
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Protein
Q99N80
Organism: Mus musculus/domesticus
Length: 567  
Fragment?: false
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Protein
A2AE95
Organism: Mus musculus/domesticus
Length: 503  
Fragment?: false
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Protein
Q6KAP5
Organism: Mus musculus/domesticus
Length: 590  
Fragment?: true
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Protein
A2AE94
Organism: Mus musculus/domesticus
Length: 568  
Fragment?: false
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Publication
22219378 | -
First Author: Hokanson DE
Year: 2012
Journal: Mol Biol Cell
Title: EPI64 interacts with Slp1/JFC1 to coordinate Rab8a and Arf6 membrane trafficking.
Volume: 23
Issue: 4
Pages: 701-15
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Publication
11278853 | -
First Author: McAdara Berkowitz JK
Year: 2001
Journal: J Biol Chem
Title: JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase.
Volume: 276
Issue: 22
Pages: 18855-62
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Publication
27018596 | J:234701
First Author: Yokoyama T
Year: 2016
Journal: J Clin Invest
Title: MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis.
Volume: 126
Issue: 5
Pages: 1664-78
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Publication
27701149 | J:239621
First Author: Kurz AR
Year: 2016
Journal: J Clin Invest
Title: MST1-dependent vesicle trafficking regulates neutrophil transmigration through the vascular basement membrane.
Volume: 126
Issue: 11
Pages: 4125-4139
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Protein Coding Gene
MGP_CAROLIEiJ_G0026585 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028890 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028849 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028802 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028872 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028586 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1933365 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029314 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028019 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028552 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028668 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028802 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028694 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027740 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028099 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028918 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027566 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Liver
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Skeletal Muscle
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1933796
Age: postnatal adult
Specimen Label: Testis
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:1933796
Age: embryonic day 7.0
Specimen Label: E7
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:1933796
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:1933796
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:1933644
Assay Type: RT-PCR
Annotation Date: 2001-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:1933796
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 12
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Publication
23223571 | J:200233
First Author: Wang H
Year: 2013
Journal: Mol Biol Cell
Title: The Rab27a effector exophilin7 promotes fusion of secretory granules that have not been docked to the plasma membrane.
Volume: 24
Issue: 3
Pages: 319-30
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Publication
18477466 | J:138210
First Author: Saegusa C
Year: 2008
Journal: Arch Biochem Biophys
Title: Expression of Rab27B-binding protein Slp1 in pancreatic acinar cells and its involvement in amylase secretion.
Volume: 475
Issue: 1
Pages: 87-92
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Publication
30748033 | J:276845
First Author: Ramadass M
Year: 2019
Journal: J Leukoc Biol
Title: The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration.
Volume: 105
Issue: 6
Pages: 1209-1224
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Publication
11243866 | J:68115
First Author: Fukuda M
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins.
Volume: 281
Issue: 5
Pages: 1226-33
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Publication
11773082 | J:75312
First Author: Kuroda TS
Year: 2002
Journal: J Biol Chem
Title: The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.
Volume: 277
Issue: 11
Pages: 9212-8
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Publication
12590134 | J:83162
First Author: Fukuda M
Year: 2003
Journal: J Biol Chem
Title: Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.
Volume: 278
Issue: 17
Pages: 15390-6
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Publication
24652767 | J:213427
First Author: Adissu HA
Year: 2014
Journal: Dis Model Mech
Title: Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.
Volume: 7
Issue: 5
Pages: 515-24
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Publication
19906978 | J:154739
First Author: Quina LA
Year: 2009
Journal: J Neurosci
Title: Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.
Volume: 29
Issue: 45
Pages: 14309-22
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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