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Search results 1 to 100 out of 288 for Syvn1

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
84447 | SYVN1
Type: gene
Organism: human
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Gene
361712 | Syvn1
Type: gene
Organism: rat
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Gene
508358 | SYVN1
Type: gene
Organism: cattle
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Gene
335226 | syvn1
Type: gene
Organism: zebrafish
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Gene
716698 | SYVN1
Type: gene
Organism: macaque, rhesus
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Gene
100327246 | syvn1
Type: gene
Organism: frog, western clawed
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Gene
483746 | SYVN1
Type: gene
Organism: dog, domestic
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Gene
466660 | SYVN1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1921376 | Syvn1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26358086 | J:277978
 
First Author: Yang S
Year: 2015
Journal: Sci Rep
Title: Experimental study of the protective effects of SYVN1 against diabetic retinopathy.
Volume: 5
Pages: 14036
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Gene
6400 | SEL1L
Type: gene
Organism: human
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Gene
80343 | SEL1L2
Type: gene
Organism: human
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Publication
25698262 | J:220710
First Author: Fujita H
Year: 2015
Journal: EMBO J
Title: The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of PGC-1β.
Volume: 34
Issue: 8
Pages: 1042-55
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Protein Coding Gene
MGP_CAROLIEiJ_G0022583 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024703 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024703 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024471 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1921376 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025150 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0024443 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024570 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024536 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024656 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024566 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023689 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024005 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014077 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023494 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12975321 | J:86009
First Author: Amano T
Year: 2003
Journal: Genes Dev
Title: Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy.
Volume: 17
Issue: 19
Pages: 2436-49
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Publication
17059562 | J:119960
First Author: Omura T
Year: 2006
Journal: J Neurochem
Title: A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin.
Volume: 99
Issue: 6
Pages: 1456-69
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Publication
36924492 | J:334885
First Author: Kawano T
Year: 2023
Journal: Cell Rep
Title: ER proteostasis regulators cell-non-autonomously control sleep.
Volume: 42
Issue: 3
Pages: 112267
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Publication
32509196 | J:307648
First Author: Chen L
Year: 2020
Journal: Am J Transl Res
Title: Energy supplementation rescues growth restriction and female infertility of mice with hepatic HRD1 ablation.
Volume: 12
Issue: 5
Pages: 2018-2027
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Publication
30201971 | J:267711
First Author: Wei J
Year: 2018
Journal: Nat Commun
Title: ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes.
Volume: 9
Issue: 1
Pages: 3659
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Publication
21049091 | J:166682
First Author: Hasegawa D
Year: 2010
Journal: PLoS One
Title: E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis.
Volume: 5
Issue: 10
Pages: e13590
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Publication
19835843 | J:155612
First Author: Shmueli A
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Targeting of gp78 for ubiquitin-mediated proteasomal degradation by Hrd1: cross-talk between E3s in the endoplasmic reticulum.
Volume: 390
Issue: 3
Pages: 758-62
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Publication
12459480 | J:80665
First Author: Kaneko M
Year: 2002
Journal: FEBS Lett
Title: Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation.
Volume: 532
Issue: 1-2
Pages: 147-52
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Publication
21454652 | J:222676
First Author: Iida Y
Year: 2011
Journal: J Biol Chem
Title: SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates.
Volume: 286
Issue: 19
Pages: 16929-39
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Publication
26137860 | J:249109
First Author: Doroudgar S
Year: 2015
Journal: Circ Res
Title: Hrd1 and ER-Associated Protein Degradation, ERAD, are Critical Elements of the Adaptive ER Stress Response in Cardiac Myocytes.
Volume: 117
Issue: 6
Pages: 536-46
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Publication
33932778 | J:305609
 
First Author: Matsumoto T
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Synoviolin is not a pathogenic factor for auto-inflammatory diseases.
Volume: 558
Pages: 183-188
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GXD Expression
GXD Expression
     
Probe: MGI:7567502
Assay Type: RT-PCR
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1745822
Stage: TS22
Assay Id: MGI:7567639
Age: embryonic day 14.5
Specimen Label: Flox/+;Cre/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7567502
Assay Type: RT-PCR
Annotation Date: 2023-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1745822
Stage: TS22
Assay Id: MGI:7567639
Age: embryonic day 14.5
Specimen Label: Flox/delta;Cre/+
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1754766
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828578
Age: embryonic day 14.5
Image: euxassay_005614_01
Specimen Label: euxassay_005614_01
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1754766
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828578
Age: embryonic day 14.5
Image: euxassay_005614_02
Specimen Label: euxassay_005614_02
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1754766
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828578
Age: embryonic day 14.5
Image: euxassay_005614_03
Specimen Label: euxassay_005614_03
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1754766
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828578
Age: embryonic day 14.5
Image: euxassay_005614_04
Specimen Label: euxassay_005614_04
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1754766
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828578
Age: embryonic day 14.5
Image: euxassay_005614_14
Specimen Label: euxassay_005614_14
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:1754766
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828578
Age: embryonic day 14.5
Image: euxassay_005614_15
Specimen Label: euxassay_005614_15
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:1754766
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828578
Age: embryonic day 14.5
Image: euxassay_005614_16
Specimen Label: euxassay_005614_16
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:1754766
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828578
Age: embryonic day 14.5
Image: euxassay_005614_17
Specimen Label: euxassay_005614_17
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:1754766
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828578
Age: embryonic day 14.5
Image: euxassay_005614_18
Specimen Label: euxassay_005614_18
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:1754766
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828578
Age: embryonic day 14.5
Image: euxassay_005614_19
Specimen Label: euxassay_005614_19
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:1754766
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828578
Age: embryonic day 14.5
Image: euxassay_005614_20
Specimen Label: euxassay_005614_20
Detected: true
Specimen Num: 11
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Publication
36238898 | J:329925
First Author: Bhattacharya A
Year: 2022
Journal: iScience
Title: SEL1L-HRD1 ER-associated degradation suppresses hepatocyte hyperproliferation and liver cancer.
Volume: 25
Issue: 10
Pages: 105183
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Publication
38365914 | J:345648
First Author: Lin LL
Year: 2024
Journal: Nat Commun
Title: SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex.
Volume: 15
Issue: 1
Pages: 1440
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Publication
31477895 | J:293367
First Author: Lu Y
Year: 2019
Journal: Nat Microbiol
Title: ER-localized Hrd1 ubiquitinates and inactivates Usp15 to promote TLR4-induced inflammation during bacterial infection.
Volume: 4
Issue: 12
Pages: 2331-2346
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Publication
25066055 | J:215786
First Author: Sha H
Year: 2014
Journal: Cell Metab
Title: The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism.
Volume: 20
Issue: 3
Pages: 458-70
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Publication
26551274 | J:230750
First Author: Sun S
Year: 2015
Journal: Nat Cell Biol
Title: IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation.
Volume: 17
Issue: 12
Pages: 1546-55
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Publication
27568564 | J:239018
First Author: Ji Y
Year: 2016
Journal: Cell Rep
Title: The Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Complex Manages a Key Checkpoint in B Cell Development.
Volume: 16
Issue: 10
Pages: 2630-2640
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Publication
27417417 | J:240827
 
First Author: Xu Y
Year: 2016
Journal: Nat Commun
Title: The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity.
Volume: 7
Pages: 12073
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Publication
30843874 | J:287908
 
First Author: Xu Y
Year: 2019
Journal: JCI Insight
Title: The E3 ligase Hrd1 stabilizes Tregs by antagonizing inflammatory cytokine-induced ER stress response.
Volume: 4
Issue: 5
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Publication
32086291 | J:291668
First Author: Wu T
Year: 2020
Journal: Diabetes
Title: HRD1, an Important Player in Pancreatic β-Cell Failure and Therapeutic Target for Type 2 Diabetic Mice.
Volume: 69
Issue: 5
Pages: 940-953
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Publication
24636985 | J:209597
First Author: Wu T
Year: 2014
Journal: Genes Dev
Title: Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis.
Volume: 28
Issue: 7
Pages: 708-22
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Publication
20160352 | J:172947
First Author: Fonseca SG
Year: 2010
Journal: J Clin Invest
Title: Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells.
Volume: 120
Issue: 3
Pages: 744-55
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Publication
36685173 | J:332826
 
First Author: Lee ES
Year: 2022
Journal: Front Physiol
Title: The effects of 4-Phenylbutyric acid on ER stress during mouse tooth development.
Volume: 13
Pages: 1079355
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Publication
30389664 | J:270482
 
First Author: Wei J
Year: 2018
Journal: EMBO J
Title: HRD1-ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination.
Volume: 37
Issue: 22
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Publication
25366967 | J:219656
First Author: Yang H
Year: 2014
Journal: J Exp Med
Title: Hrd1-mediated BLIMP-1 ubiquitination promotes dendritic cell MHCII expression for CD4 T cell priming during inflammation.
Volume: 211
Issue: 12
Pages: 2467-79
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Publication
37345654 | J:338857
 
First Author: Zhang X
Year: 2023
Journal: JCI Insight
Title: Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland.
Volume: 8
Issue: 12
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Publication
33654072 | J:308364
First Author: Zhang J
Year: 2021
Journal: Cell Death Discov
Title: Downregulation of XBP1 protects kidney against ischemia-reperfusion injury via suppressing HRD1-mediated NRF2 ubiquitylation.
Volume: 7
Issue: 1
Pages: 44
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Publication
34847358 | J:321938
First Author: Wei J
Year: 2021
Journal: Mol Cell
Title: HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease.
Volume: 81
Issue: 24
Pages: 5052-5065.e6
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Publication
33592335 | J:305762
 
First Author: Kim H
Year: 2021
Journal: Mol Metab
Title: Regulation of hepatic circadian metabolism by the E3 ubiquitin ligase HRD1-controlled CREBH/PPARα transcriptional program.
Volume: 49
Pages: 101192
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Publication
17707796 | J:296095
First Author: Kondratyev M
Year: 2007
Journal: Exp Cell Res
Title: PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress.
Volume: 313
Issue: 16
Pages: 3395-407
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Publication
19725872 | J:200386
First Author: Maeda T
Year: 2009
Journal: FEBS J
Title: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid beta-protein.
Volume: 276
Issue: 20
Pages: 5832-40
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Publication
32182217 | J:329652
First Author: Shrestha N
Year: 2020
Journal: J Clin Invest
Title: Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling.
Volume: 130
Issue: 7
Pages: 3499-3510
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Publication
21911472 | J:178646
First Author: Tsuchiya Y
Year: 2011
Journal: Mol Cell Biol
Title: Dual regulation of the transcriptional activity of Nrf1 by β-TrCP- and Hrd1-dependent degradation mechanisms.
Volume: 31
Issue: 22
Pages: 4500-12
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Publication
15611074 | J:97254
First Author: Yagishita N
Year: 2005
Journal: J Biol Chem
Title: Essential role of synoviolin in embryogenesis.
Volume: 280
Issue: 9
Pages: 7909-16
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Publication
27573825 | J:235578
First Author: Kong S
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas.
Volume: 113
Issue: 37
Pages: 10394-9
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Publication
23719816 | J:198658
First Author: Abisambra JF
Year: 2013
Journal: J Neurosci
Title: Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation.
Volume: 33
Issue: 22
Pages: 9498-507
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Publication
29907570 | J:270663
First Author: Yang Y
Year: 2018
Journal: J Biol Chem
Title: The endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls a critical checkpoint in B cell development in mice.
Volume: 293
Issue: 33
Pages: 12934-12944
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Publication
32888949 | J:319821
 
First Author: Li K
Year: 2021
Journal: Metabolism
Title: Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice.
Volume: 114
Pages: 154349
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Publication
30604742 | J:270164
First Author: Guo M
Year: 2019
Journal: Nat Commun
Title: Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth.
Volume: 10
Issue: 1
Pages: 37
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Publication
35167946 | J:321553
 
First Author: Neupane S
Year: 2022
Journal: Matrix Biol
Title: O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development.
Volume: 107
Pages: 77-96
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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