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Search results 1 to 100 out of 136 for Szt2

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
23334 | SZT2
Type: gene
Organism: human
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Gene
533805 | SZT2
Type: gene
Organism: cattle
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Gene
571986 | szt2
Type: gene
Organism: zebrafish
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Gene
702661 | SZT2
Type: gene
Organism: macaque, rhesus
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Gene
456824 | SZT2
Type: gene
Organism: chimpanzee
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Gene
362573 | Szt2
Type: gene
Organism: rat
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Gene
482532 | SZT2
Type: gene
Organism: dog, domestic
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Gene
424566 | SZT2
Type: gene
Organism: chicken
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Gene
100496044 | szt2
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR033228 | SZT2
Type: Family
Description: Szt2 (seizure threshold 2), also known as TIGR (transcript increased in glutamate resistance) is a peroxisomal protein implicated in resistance to oxidative stress. It is not a functional superoxide dismutase (SOD), but might be involved in SOD activity []. In mammals, it may serve an important role in the central nervous system [, ]. Szt2 is part of the KICSTOR complex, which functions in the amino acid-sensing branch of the TORC1 signaling pathway [].
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Protein Coding Gene
MGI:3033336 | Szt2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
19624305 | J:150942
First Author: Frankel WN
Year: 2009
Journal: Genes Brain Behav
Title: Szt2, a novel gene for seizure threshold in mice.
Volume: 8
Issue: 5
Pages: 568-76
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Publication
20045724 | J:205670
First Author: Toutzaris D
Year: 2010
Journal: Free Radic Biol Med
Title: A novel giant peroxisomal superoxide dismutase motif-containing protein.
Volume: 48
Issue: 6
Pages: 811-20
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Publication
28199306 | J:240399
First Author: Wolfson RL
Year: 2017
Journal: Nature
Title: KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
Volume: 543
Issue: 7645
Pages: 438-442
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Publication
28199315 | J:241016
First Author: Peng M
Year: 2017
Journal: Nature
Title: SZT2 dictates GATOR control of mTORC1 signalling.
Volume: 543
Issue: 7645
Pages: 433-437
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Protein
A2A9C3
Organism: Mus musculus/domesticus
Length: 3431  
Fragment?: false
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Protein
V9GXW1
Organism: Mus musculus/domesticus
Length: 559  
Fragment?: true
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Publication
23932106 | -
First Author: Basel-Vanagaite L
Year: 2013
Journal: Am J Hum Genet
Title: Biallelic SZT2 mutations cause infantile encephalopathy with epilepsy and dysmorphic corpus callosum.
Volume: 93
Issue: 3
Pages: 524-9
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Protein
Q6ZQA5
Organism: Mus musculus/domesticus
Length: 1520  
Fragment?: true
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Publication
36250465 | J:332110
 
First Author: Yin N
Year: 2022
Journal: J Clin Invest
Title: SZT2 maintains hematopoietic stem cell homeostasis via nutrient-mediated mTORC1 regulation.
Volume: 132
Issue: 20
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Gene
100873952 | SZT2-AS1
Type: gene
Organism: human
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Protein Coding Gene
MGP_CAROLIEiJ_G0026372 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028665 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028626 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028576 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028647 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028361 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3033336 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029088 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028328 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028476 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028444 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028578 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028471 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027521 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027874 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028703 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027344 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:4437753
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437816
Age: postnatal adult
Specimen Label: wild-type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4437753
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437816
Age: postnatal adult
Specimen Label: Szt2m1Frk
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4437757
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437817
Age: postnatal adult
Specimen Label: wild-type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4437757
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437817
Age: postnatal adult
Specimen Label: Szt2m1Frk
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4437758
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437818
Age: postnatal adult
Specimen Label: wild-type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4437758
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437818
Age: postnatal adult
Specimen Label: Szt2m1Frk
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4437753
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437819
Age: postnatal adult
Specimen Label: Szt2m1Frk/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4437753
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437819
Age: postnatal adult
Specimen Label: Szt2m1Frk/Szt2m1Frk
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: Gene Trap -/-
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: Gene Trap +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: Gene Trap +/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: ENU -/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: ENU +/-
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: ENU +/+
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Spinal cord
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Skeletal muscle
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:4437827
Age: embryonic day 17.5
Specimen Label: e17.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:4437827
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437827
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437827
Age: postnatal day 14
Specimen Label: p14
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437827
Age: postnatal day 21
Specimen Label: p21
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437827
Age: postnatal day 70
Specimen Label: p70
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:2467517
Assay Type: RNA in situ
Annotation Date: 2024-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7576700
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:2467517
Assay Type: RNA in situ
Annotation Date: 2024-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7576700
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
12477932 | J:82808
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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