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Search results 1 to 100 out of 108 for Taar2

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
9287 | TAAR2
Type: gene
Organism: human
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Gene
785719 | TAAR2
Type: gene
Organism: cattle
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Gene
100859322 | TAAR2
Type: gene
Organism: chicken
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Gene
714074 | TAAR2
Type: gene
Organism: macaque, rhesus
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Gene
100485003 | taar2
Type: gene
Organism: frog, western clawed
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Gene
294121 | Taar2
Type: gene
Organism: rat
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Protein Coding Gene
MGI:2685071 | Taar2
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
     
Probe: MGI:3807794
Assay Type: RNA in situ
Annotation Date: 2008-09-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3576528
Stage: TS28
Assay Id: MGI:3807903
Age: postnatal day 7
Specimen Label: 5 P7 TAAR2
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3807794
Assay Type: RNA in situ
Annotation Date: 2008-09-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3576528
Stage: TS28
Assay Id: MGI:3807903
Age: postnatal week 6-8
Specimen Label: 5 A TAAR2
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:3807794
Assay Type: RNA in situ
Annotation Date: 2008-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3576527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:3807903
Age: postnatal newborn
Note: Expression was detected in Grueneberg ganglion cells.
Specimen Label: 5 N TAAR2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3807794
Assay Type: RNA in situ
Annotation Date: 2008-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760825
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:3807903
Age: embryonic day 17.5
Note: Expression was detected in Grueneberg ganglion cells.
Specimen Label: 5 E TAAR2
Detected: true
Specimen Num: 2
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Publication
35431833 | J:323857
 
First Author: Efimova EV
Year: 2022
Journal: Front Behav Neurosci
Title: Trace Amine-Associated Receptor 2 Is Expressed in the Limbic Brain Areas and Is Involved in Dopamine Regulation and Adult Neurogenesis.
Volume: 16
Pages: 847410
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Protein Coding Gene
MGP_CAROLIEiJ_G0015176 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017077 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017055 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017017 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017017 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016837 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2685071 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017475 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016418 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016916 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016912 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016992 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016942 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017510 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016203 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016481 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023796 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015985 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:3807783
Assay Type: RT-PCR
Annotation Date: 2008-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760628
Stage: TS28
Assay Id: MGI:3807883
Age: postnatal
Specimen Label: MOE
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3807783
Assay Type: RT-PCR
Annotation Date: 2008-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3576528
Stage: TS28
Assay Id: MGI:3807883
Age: postnatal
Specimen Label: GG
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692818
Age: postnatal adult
Image: UC Davis_1852341
Specimen Label: UC Davis_1852341
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692818
Age: postnatal adult
Image: UC Davis_1852333
Specimen Label: UC Davis_1852333
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692818
Age: postnatal adult
Image: UC Davis_1852334
Specimen Label: UC Davis_1852334
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692818
Age: postnatal adult
Image: UC Davis_1852338
Note: vas deferens
Specimen Label: UC Davis_1852338
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692818
Age: postnatal adult
Image: UC Davis_1852339
Note: vas deferens
Specimen Label: UC Davis_1852339
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692818
Age: postnatal adult
Image: UC Davis_1852340
Note: vas deferens
Specimen Label: UC Davis_1852340
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:3807794
Assay Type: RNA in situ
Annotation Date: 2008-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3576527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:3807903
Age: postnatal day 0
Note: Expression was detected in the Grueneberg ganglion.
Specimen Label: 2F
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692818
Age: postnatal adult
Image: UC Davis_1852343
Specimen Label: UC Davis_1852343
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692818
Age: postnatal adult
Image: UC Davis_1852335
Specimen Label: UC Davis_1852335
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692818
Age: postnatal adult
Image: UC Davis_1852336
Specimen Label: UC Davis_1852336
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692818
Age: postnatal adult
Image: UC Davis_1852337
Specimen Label: UC Davis_1852337
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692818
Age: postnatal adult
Image: UC Davis_1852342
Specimen Label: UC Davis_1852342
Detected: true
Specimen Num: 11
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Publication
15718104 | J:95733
First Author: Lindemann L
Year: 2005
Journal: Genomics
Title: Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.
Volume: 85
Issue: 3
Pages: 372-85
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Publication
17556730 | J:124221
First Author: Fleischer J
Year: 2007
Journal: Chem Senses
Title: Expression of trace amine-associated receptors in the Grueneberg ganglion.
Volume: 32
Issue: 6
Pages: 623-31
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Allele
Del(10Taar2-Taar9)1Mcho | MGI:7496157
Name: deletion, Chr 10, Marius Hoener
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
30158871 | J:337644
 
First Author: Harmeier A
Year: 2018
Journal: Front Pharmacol
Title: How Female Mice Attract Males: A Urinary Volatile Amine Activates a Trace Amine-Associated Receptor That Induces Male Sexual Interest.
Volume: 9
Pages: 924
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Publication
34145235 | J:322210
First Author: Fei A
Year: 2021
Journal: Nat Commun
Title: Coordination of two enhancers drives expression of olfactory trace amine-associated receptors.
Volume: 12
Issue: 1
Pages: 3798
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Publication
16878137 | J:111708
First Author: Liberles SD
Year: 2006
Journal: Nature
Title: A second class of chemosensory receptors in the olfactory epithelium.
Volume: 442
Issue: 7103
Pages: 645-50
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Publication
11459929 | J:70672
First Author: Borowsky B
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Trace amines: identification of a family of mammalian G protein-coupled receptors.
Volume: 98
Issue: 16
Pages: 8966-71
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Publication
17088868 | -
First Author: Zucchi R
Year: 2006
Journal: Br J Pharmacol
Title: Trace amine-associated receptors and their ligands.
Volume: 149
Issue: 8
Pages: 967-78
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Publication
19325074 | -
First Author: Maguire JJ
Year: 2009
Journal: Pharmacol Rev
Title: International Union of Pharmacology. LXXII. Recommendations for trace amine receptor nomenclature.
Volume: 61
Issue: 1
Pages: 1-8
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Publication
11723224 | -
First Author: Bunzow JR
Year: 2001
Journal: Mol Pharmacol
Title: Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor.
Volume: 60
Issue: 6
Pages: 1181-8
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Publication
15860375 | -
First Author: Lindemann L
Year: 2005
Journal: Trends Pharmacol Sci
Title: A renaissance in trace amines inspired by a novel GPCR family.
Volume: 26
Issue: 5
Pages: 274-81
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Publication
16451074 | -
First Author: Hart ME
Year: 2006
Journal: J Med Chem
Title: Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues.
Volume: 49
Issue: 3
Pages: 1101-12
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Publication
19237578 | -
First Author: Hussain A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Positive Darwinian selection and the birth of an olfactory receptor clade in teleosts.
Volume: 106
Issue: 11
Pages: 4313-8
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Publication
15891052 | -
 
First Author: Gloriam DE
Year: 2005
Journal: Ann N Y Acad Sci
Title: High species variation within the repertoire of trace amine receptors.
Volume: 1040
Pages: 323-7
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Publication
14559210 | -
First Author: Vanti WB
Year: 2003
Journal: Genomics
Title: Discovery of a null mutation in a human trace amine receptor gene.
Volume: 82
Issue: 5
Pages: 531-6
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Publication
15146179 | -
First Author: Scanlan TS
Year: 2004
Journal: Nat Med
Title: 3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone.
Volume: 10
Issue: 6
Pages: 638-42
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Publication
19686131 | -
 
First Author: Liberles SD
Year: 2009
Journal: Ann N Y Acad Sci
Title: Trace amine-associated receptors are olfactory receptors in vertebrates.
Volume: 1170
Pages: 168-72
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Publication
22038157 | -
First Author: Panas MW
Year: 2012
Journal: J Neuroimmune Pharmacol
Title: Trace amine associated receptor 1 signaling in activated lymphocytes.
Volume: 7
Issue: 4
Pages: 866-76
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Protein Domain
IPR009132 | TAAR_fam
Type: Family
Description: Trace amines, such as tyramine, beta-phenylethylamine, tryptamine and octopamine are biogenic amines present in trace levels in mammalian nervous systems []. Although some "trace amines"have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative []. Recently, a novel family of G protein-coupled receptors that share sequence similarity with the classical amine receptors has been discovered []. These trace amine associated receptors (TAAR), also known as trace amine receptors (TAR or TA), are members of the rhodopsin-like G-protein coupled receptor (GPCR) family [, ]. Some members have been shown to act as receptors for tyramine and beta-phenylethylamine, supporting a role for trace amines as neurotransmitters in vertebrates []. However, not all members have a high affinity for trace amines, some for example are olfactory receptors, which is why they are classified as trace amine associated receptors [].Since trace amine associated receptors are putative endogenous receptors for trace amines, they are of interest the pharmaceutical industry, since they are metabolic derivatives of classical biogenic amines and the psychostimulants amphetamine and methamphetamine [, , ].Trace amine-associated receptors are found in a range of taxa, but not all the members are found in all taxa [, , , ]and act as different types of receptor. In mammals, for example, TAAR1 is probably a receptor for thyronamines, decarboxylated and deiodinated metabolites of the thyroid hormones []whilst in mouse TAAR2 to TAAR9 receptors are most probably olfactory receptors for volatile amines [, ].This entry represents the trace amine associated receptor family.
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Protein Domain
IPR009133 | TAAR1
Type: Family
Description: Trace amines, such as tyramine, beta-phenylethylamine, tryptamine and octopamine are biogenic amines present in trace levels in mammalian nervous systems []. Although some "trace amines"have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative []. Recently, a novel family of G protein-coupled receptors that share sequence similarity with the classical amine receptors has been discovered []. These trace amine associated receptors (TAAR), also known as trace amine receptors (TAR or TA), are members of the rhodopsin-like G-protein coupled receptor (GPCR) family [, ]. Some members have been shown to act as receptors for tyramine and beta-phenylethylamine, supporting a role for trace amines as neurotransmitters in vertebrates []. However, not all members have a high affinity for trace amines, some for example are olfactory receptors, which is why they are classified as trace amine associated receptors [].Since trace amine associated receptors are putative endogenous receptors for trace amines, they are of interest the pharmaceutical industry, since they are metabolic derivatives of classical biogenic amines and the psychostimulants amphetamine and methamphetamine [, , ].Trace amine-associated receptors are found in a range of taxa, but not all the members are found in all taxa [, , , ]and act as different types of receptor. In mammals, for example, TAAR1 is probably a receptor for thyronamines, decarboxylated and deiodinated metabolites of the thyroid hormones []whilst in mouse TAAR2 to TAAR9 receptors are most probably olfactory receptors for volatile amines [, ].This entry represents trace amine receptor 1 (TAAR1), it is potently activated by tyramine and beta-phenylethylamine, and displays low affinity for tryptamine, octopamine and dopamine []. TAAR1 is believed to be a key regulator of common and trace brain monoamines, and may also play some role in immune system function []. It is expressed at low to moderate levels in peripheral tissues such as the stomach, kidney and lung, and within the central nervous system is restricted predominantly to the amygdala [].
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Protein
Q923Y8
Organism: Mus musculus/domesticus
Length: 332  
Fragment?: false
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Protein
Q5QD06
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
Q5QD05
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
Q5QD07
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
Q5QD10
Organism: Mus musculus/domesticus
Length: 358  
Fragment?: false
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Protein
Q5QD13
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: false
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Protein
Q5QD04
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
Q5QD08
Organism: Mus musculus/domesticus
Length: 358  
Fragment?: false
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Protein
Q5QD16
Organism: Mus musculus/domesticus
Length: 343  
Fragment?: false
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Protein
Q5QD15
Organism: Mus musculus/domesticus
Length: 347  
Fragment?: false
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Protein
Q5QD17
Organism: Mus musculus/domesticus
Length: 339  
Fragment?: false
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Protein
Q5QD09
Organism: Mus musculus/domesticus
Length: 358  
Fragment?: false
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Protein
Q5QD12
Organism: Mus musculus/domesticus
Length: 358  
Fragment?: false
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Protein
Q5QD11
Organism: Mus musculus/domesticus
Length: 358  
Fragment?: false
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