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Search results 1 to 100 out of 106 for Tab3

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
257397 | TAB3
Type: gene
Organism: human
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Gene
317546 | Tab3
Type: gene
Organism: rat
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Gene
473550 | TAB3
Type: gene
Organism: chimpanzee
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Gene
788288 | TAB3
Type: gene
Organism: cattle
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Gene
418588 | TAB3
Type: gene
Organism: chicken
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Gene
566547 | tab3
Type: gene
Organism: zebrafish
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Gene
707630 | TAB3
Type: gene
Organism: macaque, rhesus
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Gene
100495158 | tab3
Type: gene
Organism: frog, western clawed
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Gene
491807 | TAB3
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1913974 | Tab3
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
727682 | TAB3-AS1
Type: gene
Organism: human
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Gene
100873926 | TAB3-AS2
Type: gene
Organism: human
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Publication
28462515 | J:302264
First Author: Sheng Y
Year: 2017
Journal: Cell Biol Int
Title: TAB3 defect induces augmented cardioprotection loss from ischemic injury.
Volume: 41
Issue: 7
Pages: 787-797
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Publication
18345001 | J:133259
First Author: Shi M
Year: 2008
Journal: Nat Immunol
Title: TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation.
Volume: 9
Issue: 4
Pages: 369-77
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Publication
23509369 | J:195289
First Author: Ori D
Year: 2013
Journal: J Immunol
Title: Essential roles of K63-linked polyubiquitin-binding proteins TAB2 and TAB3 in B cell activation via MAPKs.
Volume: 190
Issue: 8
Pages: 4037-45
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Publication
36593296 | J:338377
First Author: Sun L
Year: 2023
Journal: Nat Microbiol
Title: Staphylococcal virulence factor HlgB targets the endoplasmic-reticulum-resident E3 ubiquitin ligase AMFR to promote pneumonia.
Volume: 8
Issue: 1
Pages: 107-120
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Publication
19927120 | J:155547
First Author: Sato Y
Year: 2009
Journal: EMBO J
Title: Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3.
Volume: 28
Issue: 24
Pages: 3903-9
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Publication
19955178 | J:159772
First Author: Broglie P
Year: 2010
Journal: J Biol Chem
Title: Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway.
Volume: 285
Issue: 4
Pages: 2333-9
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Protein Coding Gene
MGP_CAROLIEiJ_G0033216 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035888 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035873 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035791 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035564 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1913974 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036385 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034853 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035539 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035694 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035633 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035783 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035670 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036412 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034551 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034992 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031758 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034381 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:6275979
Age: embryonic day 13.5
Specimen Label: Liver
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737321
Stage: TS21
Assay Id: MGI:6275979
Age: embryonic day 13.5
Specimen Label: Kidney
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:6275979
Age: embryonic day 13.5
Specimen Label: Heart
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6275979
Age: embryonic day 13.5
Specimen Label: Brain
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672821
Stage: TS21
Assay Id: MGI:6275979
Age: embryonic day 13.5
Specimen Label: Lung
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:6275979
Age: postnatal month 3
Specimen Label: Ovary
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6275979
Age: postnatal month 3
Specimen Label: Liver
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6275979
Age: postnatal month 3
Specimen Label: Kidney
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:6275979
Age: postnatal month 3
Specimen Label: Adrenal gland
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6275979
Age: postnatal month 3
Specimen Label: Spleen
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6275979
Age: postnatal month 3
Specimen Label: Brain
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6275979
Age: postnatal month 3
Specimen Label: Heart
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:6275815
Assay Type: RT-PCR
Annotation Date: 2019-02-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6275979
Age: postnatal month 3
Specimen Label: Testis
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:3062215
Assay Type: RNA in situ
Annotation Date: 2004-12-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286019
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:3511233
Age: embryonic day 11.5
Image: 2N
Note: Expression restricted to the distal epithelium.
Specimen Label: 2N
Detected: true
Specimen Num: 1
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Publication
31127032 | J:276968
First Author: Lei CQ
Year: 2019
Journal: J Immunol
Title: USP19 Inhibits TNF-α- and IL-1β-Triggered NF-κB Activation by Deubiquitinating TAK1.
Volume: 203
Issue: 1
Pages: 259-268
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Publication
17431699 | J:121917
First Author: Olesen C
Year: 2007
Journal: Cell Tissue Res
Title: Global gene expression analysis in fetal mouse ovaries with and without meiosis and comparison of selected genes with meiosis in the testis.
Volume: 328
Issue: 1
Pages: 207-21
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Publication
19136968 | J:158069
First Author: Tokunaga F
Year: 2009
Journal: Nat Cell Biol
Title: Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.
Volume: 11
Issue: 2
Pages: 123-32
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Publication
26474655 | J:233920
First Author: Panda S
Year: 2015
Journal: Immunity
Title: Deubiquitinase MYSM1 Regulates Innate Immunity through Inactivation of TRAF3 and TRAF6 Complexes.
Volume: 43
Issue: 4
Pages: 647-59
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Publication
15328023 | J:93154
First Author: Lü J
Year: 2004
Journal: Dev Biol
Title: Global analysis of genes differentially expressed in branching and non-branching regions of the mouse embryonic lung.
Volume: 273
Issue: 2
Pages: 418-35
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Publication
20548051 | J:163340
First Author: Cox BJ
Year: 2010
Journal: Genome Res
Title: Phenotypic annotation of the mouse X chromosome.
Volume: 20
Issue: 8
Pages: 1154-64
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Publication
- | J:160967
     
First Author: Cox BJ
Year: 2010
Journal: MGI Direct Data Submission
Title: Phenotypic annotation of the mouse X chromosome
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Publication
- | J:345476
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
14633987 | -
First Author: Ishitani T
Year: 2003
Journal: EMBO J
Title: Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling.
Volume: 22
Issue: 23
Pages: 6277-88
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Interaction Experiment
Shi M (2008)
Description: TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation.
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Publication
35417191 | J:326758
First Author: Wang JN
Year: 2022
Journal: Sci Transl Med
Title: Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms.
Volume: 14
Issue: 640
Pages: eabk2709
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Interaction Experiment
Hong S (2007)
Description: Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2.
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Publication
17384642 | -
First Author: Hong S
Year: 2007
Journal: Nat Immunol
Title: Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2.
Volume: 8
Issue: 5
Pages: 504-13
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Publication
19935683 | -
First Author: Kulathu Y
Year: 2009
Journal: Nat Struct Mol Biol
Title: Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain.
Volume: 16
Issue: 12
Pages: 1328-30
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Publication
17449468 | -
First Author: Tian Y
Year: 2007
Journal: J Biol Chem
Title: RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation.
Volume: 282
Issue: 23
Pages: 16776-82
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Publication
10882101 | -
First Author: Takaesu G
Year: 2000
Journal: Mol Cell
Title: TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway.
Volume: 5
Issue: 4
Pages: 649-58
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Protein Domain
IPR041911 | TAB2/3_CUE
Type: Domain
Description: TAB2 (TGF-beta-activated kinase 1 and MAP3K7-binding protein 2) is an adaptor protein that regulates activation of TAK1, a MAP kinase kinase kinase (MAPKKK), through linking TAK1 to TRAF6 in the Interleukin-1 (IL-1) induced NF-kappaB activation pathway []. TAB3 is a TAB2-like TAK1-binding protein that activates NF-kappaB similar to TAB2 []. It activates TAK1 and regulates its association with TRAF2 and TRAF6. Moreover, TAB3 interacts with TRAF6 and TRAF2 in an IL-1- and a TNF-dependent manner, respectively. TAB2 and TAB3 function redundantly as mediators of TAK1 activation in IL-1 and TNF signal transduction []. Both of them contain an N-terminal CUE domain, a coiled-coil (CC) region, a TAK1-binding domain and a C-terminal Npl4 zinc finger (NZF) ubiquitin-binding domain (UBD) [].This entry represents the CUE domain found in TAB2 and TAB3.
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Protein
F7AT87
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
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Protein
D3Z216
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: true
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