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Search results 1 to 100 out of 409 for Tacr1

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
6869 | TACR1
Type: gene
Organism: human
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Gene
407133 | TACR1
Type: gene
Organism: cattle
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Gene
395677 | TACR1
Type: gene
Organism: chicken
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Gene
653008 | TACR1
Type: gene
Organism: macaque, rhesus
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Gene
100127678 | tacr1
Type: gene
Organism: frog, western clawed
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Gene
24807 | Tacr1
Type: gene
Organism: rat
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Gene
403815 | TACR1
Type: gene
Organism: dog, domestic
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Gene
470412 | TACR1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:98475 | Tacr1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:7543758
Assay Type: RNA in situ
Annotation Date: 2023-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3565728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7543898
Age: postnatal adult
Image: S6A - Tacr1
Note: High levels of colocalization are seen with Oprm1.
Specimen Label: S6A - Tacr1
Detected: true
Specimen Num: 1
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Publication
28150369 | J:331013
First Author: Nelson BS
Year: 2018
Journal: Addict Biol
Title: Bidirectional relationship between alcohol intake and sensitivity to social defeat: association with Tacr1 and Avp expression.
Volume: 23
Issue: 1
Pages: 142-153
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GXD Expression
GXD Expression
Probe: MGI:6758933
Assay Type: RNA in situ
Annotation Date: 2023-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3565728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7543881
Age: postnatal adult
Image: S6A - Tacr1
Note: High levels of colocalization are seen with Tacr1.
Specimen Label: S6A - Tacr1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6184666
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191414
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Tacr1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6184666
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191414
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Tacr1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6184666
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191414
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Tacr1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6184666
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191414
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Tacr1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6184666
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191414
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Tacr1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6184666
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191414
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Tacr1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6184666
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191414
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Tacr1
Detected: true
Specimen Num: 7
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Publication
27712014 | J:237538
First Author: Huang H
Year: 2016
Journal: Genesis
Title: Generation of a NK1R-CreER knockin mouse strain to study cells involved in Neurokinin 1 Receptor signaling.
Volume: 54
Issue: 11
Pages: 593-601
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Publication
33591273 | J:316084
   
First Author: Barik A
Year: 2021
Journal: Elife
Title: A spinoparabrachial circuit defined by Tacr1 expression drives pain.
Volume: 10
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Publication
33051347 | J:297529
First Author: Sheahan TD
Year: 2020
Journal: J Neurosci
Title: The Neurokinin-1 Receptor is Expressed with Gastrin-Releasing Peptide Receptor in Spinal Interneurons and Modulates Itch.
Volume: 40
Issue: 46
Pages: 8816-8830
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Publication
22884624 | J:192659
 
First Author: Dudley JA
Year: 2013
Journal: Neuropharmacology
Title: Antagonism of L-type Ca(v) channels with nifedipine differentially affects performance of wildtype and NK1R-/- mice in the 5-Choice Serial Reaction-Time Task.
Volume: 64
Pages: 329-36
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Publication
33116307 | J:297417
First Author: Choi S
Year: 2020
Journal: Nature
Title: Parallel ascending spinal pathways for affective touch and pain.
Volume: 587
Issue: 7833
Pages: 258-263
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Publication
23499760 | J:335063
 
First Author: Botz B
Year: 2013
Journal: Peptides
Title: Role of Pituitary Adenylate-Cyclase Activating Polypeptide and Tac1 gene derived tachykinins in sensory, motor and vascular functions under normal and neuropathic conditions.
Volume: 43
Pages: 105-12
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Publication
22471406 | J:198035
First Author: Berger A
Year: 2012
Journal: Genes Brain Behav
Title: Diminished pheromone-induced sexual behavior in neurokinin-1 receptor deficient (TACR1(-/-)) mice.
Volume: 11
Issue: 5
Pages: 568-76
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Publication
29459872 | J:337316
 
First Author: Pakai E
Year: 2018
Journal: Front Immunol
Title: The Neurokinin-1 Receptor Contributes to the Early Phase of Lipopolysaccharide-Induced Fever via Stimulation of Peripheral Cyclooxygenase-2 Protein Expression in Mice.
Volume: 9
Pages: 166
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Publication
32289251 | J:294594
First Author: Chiang MC
Year: 2020
Journal: Neuron
Title: Divergent Neural Pathways Emanating from the Lateral Parabrachial Nucleus Mediate Distinct Components of the Pain Response.
Volume: 106
Issue: 6
Pages: 927-939.e5
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Publication
34730998 | J:319932
First Author: Xu Q
Year: 2021
Journal: Sci Adv
Title: Astrocytes contribute to pain gating in the spinal cord.
Volume: 7
Issue: 45
Pages: eabi6287
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Protein Coding Gene
MGP_CAROLIEiJ_G0028529 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030873 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030883 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030827 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_98475 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031343 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029992 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030570 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030802 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030712 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029707 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030073 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022264 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029535 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
17434199 | J:343056
First Author: Makhortova NR
Year: 2007
Journal: Virology
Title: Neurokinin-1 enables measles virus trans-synaptic spread in neurons.
Volume: 362
Issue: 1
Pages: 235-44
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Publication
14622216 | J:89627
First Author: Morcuende S
Year: 2003
Journal: Eur J Neurosci
Title: Increased neurogenesis and brain-derived neurotrophic factor in neurokinin-1 receptor gene knockout mice.
Volume: 18
Issue: 7
Pages: 1828-36
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Publication
15814105 | J:102131
First Author: Herpfer I
Year: 2005
Journal: Neuropharmacology
Title: A comparison of neurokinin 1 receptor knock-out (NK1-/-) and wildtype mice: exploratory behaviour and extracellular noradrenaline concentration in the cerebral cortex of anaesthetised subjects.
Volume: 48
Issue: 5
Pages: 706-19
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Publication
14614952 | J:97157
First Author: Suzuki R
Year: 2003
Journal: Neuropharmacology
Title: The coding of noxious mechanical and thermal stimuli of deep dorsal horn neurones is attenuated in NK1 knockout mice.
Volume: 45
Issue: 8
Pages: 1093-100
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Publication
25558794 | J:235929
First Author: Porter AJ
Year: 2015
Journal: Genes Brain Behav
Title: A lack of functional NK1 receptors explains most, but not all, abnormal behaviours of NK1R-/- mice(1).
Volume: 14
Issue: 2
Pages: 189-99
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Publication
12527475 | J:97375
First Author: Ripley TL
Year: 2002
Journal: Neuropharmacology
Title: Lack of self-administration and behavioural sensitisation to morphine, but not cocaine, in mice lacking NK1 receptors.
Volume: 43
Issue: 8
Pages: 1258-68
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Publication
9748515 | J:171881
First Author: Pommier Y
Year: 1998
Journal: Biochim Biophys Acta
Title: Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme.
Volume: 1400
Issue: 1-3
Pages: 83-105
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Publication
10954331 | J:106301
First Author: Ptak K
Year: 2000
Journal: Pflugers Arch
Title: Substance P and central respiratory activity: a comparative in vitro study in NK1 receptor knockout and wild-type mice.
Volume: 440
Issue: 3
Pages: 446-51
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Publication
18276852 | J:132270
First Author: George DT
Year: 2008
Journal: Science
Title: Neurokinin 1 receptor antagonism as a possible therapy for alcoholism.
Volume: 319
Issue: 5869
Pages: 1536-9
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Publication
10854767 | J:119247
First Author: Laird JM
Year: 2000
Journal: Neuroscience
Title: Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene.
Volume: 98
Issue: 2
Pages: 345-52
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Publication
26876733 | J:307719
First Author: Moyes AJ
Year: 2016
Journal: Exp Physiol
Title: Raised arterial blood pressure in neurokinin-1 receptor-deficient mice (NK1R(-/-) ): evidence for a neural rather than a vascular mechanism.
Volume: 101
Issue: 5
Pages: 588-98
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Publication
17331215 | J:119793
First Author: Fisher AS
Year: 2007
Journal: Eur J Neurosci
Title: Disruption of noradrenergic transmission and the behavioural response to a novel environment in NK1R-/- mice.
Volume: 25
Issue: 4
Pages: 1195-204
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Publication
22155476 | J:185102
First Author: Roche M
Year: 2012
Journal: Behav Brain Res
Title: Neurokinin-1 receptor deletion modulates behavioural and neurochemical alterations in an animal model of depression.
Volume: 228
Issue: 1
Pages: 91-8
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Publication
15208590 | J:105592
First Author: De Swert KO
Year: 2004
Journal: J Allergy Clin Immunol
Title: The role of the tachykinin NK1 receptor in airway changes in a mouse model of allergic asthma.
Volume: 113
Issue: 6
Pages: 1093-9
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Publication
17914449 | J:133460
First Author: Pavlovic S
Year: 2008
Journal: J Invest Dermatol
Title: Further exploring the brain-skin connection: stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice.
Volume: 128
Issue: 2
Pages: 434-46
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Publication
18279320 | J:132717
First Author: McCutcheon JE
Year: 2008
Journal: Eur J Neurosci
Title: Genetic background influences the behavioural and molecular consequences of neurokinin-1 receptor knockout.
Volume: 27
Issue: 3
Pages: 683-90
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Publication
14625445 | J:103700
First Author: Kidd BL
Year: 2003
Journal: Neuroreport
Title: Inhibition of inflammation and hyperalgesia in NK-1 receptor knock-out mice.
Volume: 14
Issue: 17
Pages: 2189-92
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Publication
15236323 | J:109748
First Author: Löffler S
Year: 2004
Journal: Mol Reprod Dev
Title: Increased formation of corpora lutea in neurokinin 1-receptor deficient mice.
Volume: 68
Issue: 4
Pages: 408-14
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Publication
21408181 | J:171708
First Author: Yan TC
Year: 2011
Journal: PLoS One
Title: Performance deficits of NK1 receptor knockout mice in the 5-choice serial reaction-time task: effects of d-amphetamine, stress and time of day.
Volume: 6
Issue: 3
Pages: e17586
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Publication
34079054 | J:314356
First Author: van der Veen B
Year: 2021
Journal: Commun Biol
Title: Control of impulsivity by Gi-protein signalling in layer-5 pyramidal neurons of the anterior cingulate cortex.
Volume: 4
Issue: 1
Pages: 662
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Publication
11166975 | J:102989
First Author: Laird JM
Year: 2001
Journal: Pain
Title: Role of central and peripheral tachykinin NK1 receptors in capsaicin-induced pain and hyperalgesia in mice.
Volume: 90
Issue: 1-2
Pages: 97-103
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Publication
11157089 | J:109375
First Author: Bester H
Year: 2001
Journal: J Neurosci
Title: The NK1 receptor is essential for the full expression of noxious inhibitory controls in the mouse.
Volume: 21
Issue: 3
Pages: 1039-46
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Publication
15813946 | J:101074
First Author: Musazzi L
Year: 2005
Journal: Eur J Neurosci
Title: Changes in signaling pathways regulating neuroplasticity induced by neurokinin 1 receptor knockout.
Volume: 21
Issue: 5
Pages: 1370-8
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Publication
10817594 | J:103675
First Author: Martinez-Caro L
Year: 2000
Journal: Neuroreport
Title: Allodynia and hyperalgesia evoked by sciatic mononeuropathy in NKI receptor knockout mice.
Volume: 11
Issue: 6
Pages: 1213-7
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Publication
12967989 | J:85557
First Author: Gadd CA
Year: 2003
Journal: J Neurosci
Title: Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse.
Volume: 23
Issue: 23
Pages: 8271-80
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Publication
15145704 | J:101877
First Author: David DJ
Year: 2004
Journal: Eur J Pharmacol
Title: Serotonin transporter in substance P (neurokinin 1) receptor knock-out mice.
Volume: 492
Issue: 1
Pages: 41-8
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Publication
15964684 | J:106631
First Author: King T
Year: 2005
Journal: Pain
Title: Role of NK-1 neurotransmission in opioid-induced hyperalgesia.
Volume: 116
Issue: 3
Pages: 276-88
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Publication
12492418 | J:89428
First Author: Ptak K
Year: 2002
Journal: Eur J Neurosci
Title: The murine neurokinin NK1 receptor gene contributes to the adult hypoxic facilitation of ventilation.
Volume: 16
Issue: 12
Pages: 2245-52
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Publication
12473075 | J:89427
First Author: Rigual R
Year: 2002
Journal: Eur J Neurosci
Title: Chemoreceptor activity is normal in mice lacking the NK1 receptor.
Volume: 16
Issue: 11
Pages: 2078-84
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Publication
25703442 | J:330944
First Author: Porter AJ
Year: 2015
Journal: Eur Neuropsychopharmacol
Title: The angiotensin converting enzyme inhibitor, captopril, prevents the hyperactivity and impulsivity of neurokinin-1 receptor gene 'knockout' mice: sex differences and implications for the treatment of attention deficit hyperactivity disorder.
Volume: 25
Issue: 4
Pages: 512-21
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Publication
18987361 | J:147241
First Author: Janelsins BM
Year: 2009
Journal: Blood
Title: Proinflammatory tachykinins that signal through the neurokinin 1 receptor promote survival of dendritic cells and potent cellular immunity.
Volume: 113
Issue: 13
Pages: 3017-26
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Publication
14614953 | J:97156
First Author: Lever IJ
Year: 2003
Journal: Neuropharmacology
Title: Basal and activity-induced release of substance P from primary afferent fibres in NK1 receptor knockout mice: evidence for negative feedback.
Volume: 45
Issue: 8
Pages: 1101-10
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Publication
21562162 | J:175490
First Author: Chauhan VS
Year: 2011
Journal: J Immunol
Title: Prophylactic and therapeutic targeting of the neurokinin-1 receptor limits neuroinflammation in a murine model of pneumococcal meningitis.
Volume: 186
Issue: 12
Pages: 7255-63
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Publication
10702392 | J:60744
First Author: Saban R
Year: 2000
Journal: Am J Pathol
Title: Neurokinin-1 (NK-1) receptor is required in antigen-induced cystitis.
Volume: 156
Issue: 3
Pages: 775-80
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Publication
16269189 | J:112775
First Author: Costa SK
Year: 2006
Journal: J Neuroimmunol
Title: Pivotal role of endogenous tachykinins and the NK1 receptor in mediating leukocyte accumulation, in the absence of oedema formation, in response to TNFalpha in the cutaneous microvasculature.
Volume: 171
Issue: 1-2
Pages: 99-109
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Publication
17869190 | J:140285
First Author: Grasemann H
Year: 2007
Journal: Respir Physiol Neurobiol
Title: Ventilatory responses to acute hypoxia in neurokinin-1 receptor deficient mice.
Volume: 159
Issue: 2
Pages: 227-31
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Publication
11738504 | J:85904
First Author: Cao T
Year: 2001
Journal: Neuroscience
Title: Lack of a significant effect of deletion of the tachykinin neurokinin-1 receptor on wound healing in mouse skin.
Volume: 108
Issue: 4
Pages: 695-700
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Publication
10444554 | J:56869
First Author: Cao T
Year: 1999
Journal: Am J Physiol
Title: Use of NK(1) knockout mice to analyze substance P-induced edema formation.
Volume: 277
Issue: 2 Pt 2
Pages: R476-81
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Publication
9541482 | J:118792
First Author: Castagliuolo I
Year: 1998
Journal: J Clin Invest
Title: Neurokinin-1 (NK-1) receptor is required in Clostridium difficile- induced enteritis.
Volume: 101
Issue: 8
Pages: 1547-50
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Publication
20889569 | J:166250
First Author: Koon HW
Year: 2010
Journal: Am J Pathol
Title: Substance P modulates colitis-associated fibrosis.
Volume: 177
Issue: 5
Pages: 2300-9
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Publication
12010776 | J:103176
First Author: Castagliuolo I
Year: 2002
Journal: Br J Pharmacol
Title: Protective effects of neurokinin-1 receptor during colitis in mice: role of the epidermal growth factor receptor.
Volume: 136
Issue: 2
Pages: 271-9
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Publication
11465604 | J:106546
First Author: Weng HR
Year: 2001
Journal: Anesthesiology
Title: Sensory processing in the deep spinal dorsal horn of neurokinin-1 receptor knockout mice.
Volume: 94
Issue: 6
Pages: 1105-12
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Publication
10799908 | J:62122
First Author: Cao T
Year: 2000
Journal: J Immunol
Title: Neurokinin-1 receptor agonists are involved in mediating neutrophil accumulation in the inflamed, but not normal, cutaneous microvasculature: an in vivo study using neurokinin-1 receptor knockout mice.
Volume: 164
Issue: 10
Pages: 5424-9
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Publication
16272337 | J:119699
First Author: Svensson A
Year: 2005
Journal: J Immunol
Title: Neurokinin 1 receptor signaling affects the local innate immune defense against genital herpes virus infection.
Volume: 175
Issue: 10
Pages: 6802-11
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Publication
10739640 | J:61658
First Author: Mansikka H
Year: 2000
Journal: Exp Neurol
Title: Nerve injury-induced mechanical but not thermal hyperalgesia is attenuated in neurokinin-1 receptor knockout mice.
Volume: 162
Issue: 2
Pages: 343-9
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Publication
15618168 | J:94843
First Author: Walters N
Year: 2005
Journal: Infect Immun
Title: Enhanced immunoglobulin A response and protection against Salmonella enterica serovar typhimurium in the absence of the substance P receptor.
Volume: 73
Issue: 1
Pages: 317-24
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Publication
10600814 | J:59063
First Author: Saban R
Year: 1999
Journal: Am J Physiol
Title: Nerve-mediated motility of ileal segments isolated from NK(1) receptor knockout mice.
Volume: 277
Issue: 6 Pt 1
Pages: G1173-9
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Publication
12388184 | J:107858
First Author: Blum AM
Year: 2003
Journal: Am J Physiol Gastrointest Liver Physiol
Title: T cell substance P receptor governs antigen-elicited IFN-gamma production.
Volume: 284
Issue: 2
Pages: G197-204
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Publication
12231654 | J:105990
First Author: Grant AD
Year: 2002
Journal: J Physiol
Title: Neurokinin B induces oedema formation in mouse lung via tachykinin receptor-independent mechanisms.
Volume: 543
Issue: Pt 3
Pages: 1007-14
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Publication
16799078 | J:125777
First Author: Lucattelli M
Year: 2006
Journal: Am J Respir Crit Care Med
Title: Neurokinin-1 receptor blockade and murine lung tumorigenesis.
Volume: 174
Issue: 6
Pages: 674-83
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Publication
17640568 | J:123505
First Author: Gazzieri D
Year: 2007
Journal: Free Radic Biol Med
Title: Substance P released by TRPV1-expressing neurons produces reactive oxygen species that mediate ethanol-induced gastric injury.
Volume: 43
Issue: 4
Pages: 581-9
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Publication
12499446 | J:125999
First Author: Dozmorov I
Year: 2003
Journal: Physiol Genomics
Title: Neurokinin 1 receptors and neprilysin modulation of mouse bladder gene regulation.
Volume: 12
Issue: 3
Pages: 239-50
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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