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Search results 1 to 100 out of 107 for Taf5l

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Type Details Score
Protein Domain
IPR037826 | TAF5L
Type: Family
Description: TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65kDa subunit 5L (TAF5L) is a component of the a component of the PCAF complex, the human version of the yeast SAGA complex []. TAF5L is also a component of the STAGA transcription coactivator-HAT complex [].The transcription regulatory histone acetylation complex Spt-Ada-Gcn5 acetyltransferase (SAGA) is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes. SAGA preferentially acetylates histones H3 and H2B and deubiquitinates histone H2B []. SAGA is known as PCAF in vertebrates and PCAF acetylates nucleosomal histone H3 []. The SAGA complex consists of at least TRA1, CHD1, SPT7, TAF5, ADA3, SGF73, SPT20/ADA5, SPT8, TAF12, TAF6, HFI1/ADA1, UBP8, GCN5, ADA2, SPT3, SGF29, TAF10, TAF9, SGF11 and SUS1, and some of these components are present as two copies. The complex is built up from distinct modules, each of which has a separate function and crosslinks with either other proteins or other modules in the complex [].The STAGA transcription coactivator-HAT complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors. The STAGA complex is composed of at least SUPT3H, KAT2A, SUPT7L, TAF5L, TAF6L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9 [].
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Gene
27097 | TAF5L
Type: gene
Organism: human
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Gene
510413 | TAF5L
Type: gene
Organism: cattle
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Gene
421538 | TAF5L
Type: gene
Organism: chicken
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Gene
334055 | taf5l
Type: gene
Organism: zebrafish
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Gene
693770 | TAF5L
Type: gene
Organism: macaque, rhesus
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Gene
448469 | taf5l
Type: gene
Organism: frog, western clawed
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Gene
488982 | TAF5L
Type: gene
Organism: dog, domestic
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Gene
457807 | TAF5L
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1919039 | Taf5l
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
11564863 | J:320036
First Author: Martinez E
Year: 2001
Journal: Mol Cell Biol
Title: Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.
Volume: 21
Issue: 20
Pages: 6782-95
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Publication
9674425 | J:320277
First Author: Ogryzko VV
Year: 1998
Journal: Cell
Title: Histone-like TAFs within the PCAF histone acetylase complex.
Volume: 94
Issue: 1
Pages: 35-44
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Protein
Q91WQ5
Organism: Mus musculus/domesticus
Length: 589  
Fragment?: false
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Publication
31005419 | J:278440
First Author: Seruggia D
Year: 2019
Journal: Mol Cell
Title: TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network.
Volume: 74
Issue: 6
Pages: 1148-1163.e7
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Protein
A0A1D5RMJ9
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: true
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Protein
Q3U3C7
Organism: Mus musculus/domesticus
Length: 560  
Fragment?: true
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Publication
15647753 | -
First Author: Pray-Grant MG
Year: 2005
Journal: Nature
Title: Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation.
Volume: 433
Issue: 7024
Pages: 434-8
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Publication
25216679 | -
First Author: Han Y
Year: 2014
Journal: EMBO J
Title: Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex.
Volume: 33
Issue: 21
Pages: 2534-46
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Protein Coding Gene
MGP_CAROLIEiJ_G0031701 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034267 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034247 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034174 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034240 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033951 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1919039 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033278 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033924 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034080 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034024 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034169 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034071 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034779 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032980 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033395 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023299 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032819 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6406322
Assay Type: RT-PCR
Annotation Date: 2020-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674815
Stage: TS15
Assay Id: MGI:6406703
Age: embryonic day 9.25
Image: S9
Specimen Label: Control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6406322
Assay Type: RT-PCR
Annotation Date: 2020-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674815
Stage: TS15
Assay Id: MGI:6406703
Age: embryonic day 9.25
Image: S9
Specimen Label: TCre/+;Taf10
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2853323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1869223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13014
Specimen Label: GUDMAP:13014
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5001572
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542126
Age: embryonic day 15.5
Image: GUDMAP:13015
Specimen Label: GUDMAP:13015
Detected: true
Specimen Num: 2
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Publication
- | J:74871
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, similar to PCAF associated factor 65 beta, clone MGC: 19341 IMAGE: 4222283, mRNA, complete cds
Pages: BC013550
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Publication
17694077 | J:320276
First Author: Nagy Z
Year: 2007
Journal: Oncogene
Title: Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation.
Volume: 26
Issue: 37
Pages: 5341-57
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Publication
9880483 | J:320278
First Author: Schiltz RL
Year: 1999
Journal: J Biol Chem
Title: Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates.
Volume: 274
Issue: 3
Pages: 1189-92
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Publication
19114550 | J:320037
First Author: Nagy Z
Year: 2009
Journal: Mol Cell Biol
Title: The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.
Volume: 29
Issue: 6
Pages: 1649-60
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Publication
11406595 | J:320001
First Author: Brand M
Year: 2001
Journal: EMBO J
Title: UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation.
Volume: 20
Issue: 12
Pages: 3187-96
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Publication
10373431 | J:320038
First Author: Brand M
Year: 1999
Journal: J Biol Chem
Title: Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.
Volume: 274
Issue: 26
Pages: 18285-9
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Publication
18206972 | J:320111
First Author: Zhao Y
Year: 2008
Journal: Mol Cell
Title: A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.
Volume: 29
Issue: 1
Pages: 92-101
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Publication
28893950 | J:245730
First Author: Bardot P
Year: 2017
Journal: Development
Title: The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo.
Volume: 144
Issue: 20
Pages: 3808-3818
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Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
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Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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