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Search results 1 to 100 out of 1453 for Tagln

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Hits by Category

Hits by Strain

Type Details Score
Gene
key_980114 | Tagln
Type: gene
Organism: Not Specified
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Gene
6876 | TAGLN
Type: gene
Organism: human
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Gene
594967 | tagln
Type: gene
Organism: frog, western clawed
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Gene
106993487 | TAGLN
Type: gene
Organism: macaque, rhesus
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Gene
25123 | Tagln
Type: gene
Organism: rat
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Gene
479424 | TAGLN
Type: gene
Organism: dog, domestic
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Gene
513463 | TAGLN
Type: gene
Organism: cattle
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Gene
100615570 | TAGLN
Type: gene
Organism: chimpanzee
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Gene
396490 | TAGLN
Type: gene
Organism: chicken
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Gene
751758 | tagln
Type: gene
Organism: zebrafish
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Protein Domain
IPR029976 | TAGLN
Type: Family
Description: Transgelin (TAGLN) belongs to the calponin family, whose members have a N-terminal calponin homology domain (CH) and a C-terminal calponin-like repeat. Transgelin (also known as SM22) is an actin binding protein localised to the cytoskeletal apparatus []. Transgelin is required in agonist-induced smooth muscle contraction and is involved in cell migration [, ]. It has tumour suppressive functions in certain cells [, ].
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Protein Coding Gene
MGI:106012 | Tagln
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:1054549
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2622022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825734
Age: embryonic day 14.5
Image: Additional file 4 Tagln
Specimen Label: Additional file 4 Tagln
Detected: true
Specimen Num: 1
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Publication
29483576 | J:262618
First Author: Aldeiri B
Year: 2018
Journal: Sci Rep
Title: Abrogation of TGF-beta signalling in TAGLN expressing cells recapitulates Pentalogy of Cantrell in the mouse.
Volume: 8
Issue: 1
Pages: 3658
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Publication
34338296 | J:317269
 
First Author: Tsuji-Tamura K
Year: 2021
Journal: J Cell Sci
Title: The canonical smooth muscle cell marker TAGLN is present in endothelial cells and is involved in angiogenesis.
Volume: 134
Issue: 15
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Protein
P37804
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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Protein
A0A1L1STN8
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: true
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Publication
17082327 | -
First Author: Yang Z
Year: 2007
Journal: Mol Endocrinol
Title: Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth.
Volume: 21
Issue: 2
Pages: 343-58
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Publication
9384215 | -
First Author: Lawson D
Year: 1997
Journal: Cell Motil Cytoskeleton
Title: Fibroblast transgelin and smooth muscle SM22alpha are the same protein, the expression of which is down-regulated in many cell lines.
Volume: 38
Issue: 3
Pages: 250-7
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Publication
17464194 | -
First Author: Je HD
Year: 2007
Journal: Mol Cells
Title: SM22alpha is required for agonist-induced regulation of contractility: evidence from SM22alpha knockout mice.
Volume: 23
Issue: 2
Pages: 175-81
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Publication
12808045 | -
First Author: Gimona M
Year: 2003
Journal: Mol Biol Cell
Title: Calponin repeats regulate actin filament stability and formation of podosomes in smooth muscle cells.
Volume: 14
Issue: 6
Pages: 2482-91
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Publication
18378184 | -
First Author: Assinder SJ
Year: 2009
Journal: Int J Biochem Cell Biol
Title: Transgelin: an actin-binding protein and tumour suppressor.
Volume: 41
Issue: 3
Pages: 482-6
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Publication
38865240 | J:351035
First Author: Tan Z
Year: 2024
Journal: Cell Rep
Title: Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration.
Volume: 43
Issue: 6
Pages: 114342
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Publication
9693045 | J:49043
First Author: Stanier P
Year: 1998
Journal: Genomics
Title: Paralogous sm22alpha (Tagln) genes map to mouse chromosomes 1 and 9: further evidence for a paralogous relationship.
Volume: 51
Issue: 1
Pages: 144-7
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Publication
18245174 | J:136537
First Author: Yu H
Year: 2008
Journal: FASEB J
Title: Transgelin is a direct target of TGF-beta/Smad3-dependent epithelial cell migration in lung fibrosis.
Volume: 22
Issue: 6
Pages: 1778-89
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Publication
19841087 | J:154165
First Author: Fogelstrand P
Year: 2009
Journal: J Exp Med
Title: Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2).
Volume: 206
Issue: 11
Pages: 2397-406
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Publication
11020712 | J:69325
First Author: Kühbandner S
Year: 2000
Journal: Genesis
Title: Temporally controlled somatic mutagenesis in smooth muscle.
Volume: 28
Issue: 1
Pages: 15-22
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Publication
21778429 | J:188834
First Author: Shen D
Year: 2011
Journal: Circ Res
Title: Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells.
Volume: 109
Issue: 6
Pages: 616-28
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Publication
32493169 | J:318642
First Author: Wu W
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Mature Vascular Smooth Muscle Cells, but Not Endothelial Cells, Serve as the Major Cellular Source of Intimal Hyperplasia in Vein Grafts.
Volume: 40
Issue: 8
Pages: 1870-1890
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Publication
21212099 | J:169239
First Author: Malhowski AJ
Year: 2011
Journal: Hum Mol Genet
Title: Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
Volume: 20
Issue: 7
Pages: 1290-305
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Publication
8756287 | J:34770
First Author: Moessler H
Year: 1996
Journal: Development
Title: The SM 22 promoter directs tissue-specific expression in arterial but not in venous or visceral smooth muscle cells in transgenic mice.
Volume: 122
Issue: 8
Pages: 2415-25
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Publication
19705428 | J:152700
First Author: Mancini ML
Year: 2009
Journal: Dev Dyn
Title: Endoglin plays distinct roles in vascular smooth muscle cell recruitment and regulation of arteriovenous identity during angiogenesis.
Volume: 238
Issue: 10
Pages: 2479-93
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Publication
16887142 | J:114624
First Author: Frutkin AD
Year: 2006
Journal: J Mol Cell Cardiol
Title: A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre.
Volume: 41
Issue: 4
Pages: 724-31
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Publication
15132976 | J:118456
First Author: Wegener JW
Year: 2004
Journal: FASEB J
Title: An essential role of Cav1.2 L-type calcium channel for urinary bladder function.
Volume: 18
Issue: 10
Pages: 1159-61
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Publication
33390039 | J:343933
First Author: Sparks MA
Year: 2021
Journal: Hypertension
Title: Direct Actions of AT(1) (Type 1 Angiotensin) Receptors in Cardiomyocytes Do Not Contribute to Cardiac Hypertrophy.
Volume: 77
Issue: 2
Pages: 393-404
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Publication
22609406 | J:184892
First Author: Shen Z
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Smooth muscle protein 22 alpha-Cre is expressed in myeloid cells in mice.
Volume: 422
Issue: 4
Pages: 639-42
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Publication
27834190 | J:262021
First Author: Majesky MW
Year: 2017
Journal: Circ Res
Title: Differentiated Smooth Muscle Cells Generate a Subpopulation of Resident Vascular Progenitor Cells in the Adventitia Regulated by Klf4.
Volume: 120
Issue: 2
Pages: 296-311
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Publication
28043906 | J:265112
First Author: Qin X
Year: 2017
Journal: Gastroenterology
Title: Heterotrimeric G Stimulatory Protein α Subunit Is Required for Intestinal Smooth Muscle Contraction in Mice.
Volume: 152
Issue: 5
Pages: 1114-1125.e5
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Publication
22772757 | J:200735
First Author: Mao X
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Vascular smooth muscle cell Smad4 gene is important for mouse vascular development.
Volume: 32
Issue: 9
Pages: 2171-7
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Publication
21371421 | J:172088
First Author: Pan Y
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality.
Volume: 408
Issue: 3
Pages: 369-74
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Publication
22511778 | J:186203
First Author: Chen Z
Year: 2012
Journal: J Biol Chem
Title: DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice.
Volume: 287
Issue: 23
Pages: 19018-28
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Publication
25428889 | J:233357
First Author: Sheen CR
Year: 2015
Journal: J Bone Miner Res
Title: Pathophysiological role of vascular smooth muscle alkaline phosphatase in medial artery calcification.
Volume: 30
Issue: 5
Pages: 824-36
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Publication
20378849 | J:176638
First Author: Albinsson S
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function.
Volume: 30
Issue: 6
Pages: 1118-26
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Publication
16885339 | J:112093
First Author: Proweller A
Year: 2006
Journal: Cancer Res
Title: Impaired notch signaling promotes de novo squamous cell carcinoma formation.
Volume: 66
Issue: 15
Pages: 7438-44
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Publication
35798848 | J:326548
First Author: Ikeda S
Year: 2022
Journal: Sci Rep
Title: Smooth muscle protein 22α-Cre recombination in resting cardiac fibroblasts and hematopoietic precursors.
Volume: 12
Issue: 1
Pages: 11564
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Protein Coding Gene
MGP_CAROLIEiJ_G0032151 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034744 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034652 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034716 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034427 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_106012 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035237 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033749 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034399 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034558 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034499 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034639 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034543 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035258 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033454 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033862 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015021 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033290 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16475008 | J:106456
First Author: Zadelaar SM
Year: 2006
Journal: Transgenic Res
Title: Local Cre-mediated gene recombination in vascular smooth muscle cells in mice.
Volume: 15
Issue: 1
Pages: 31-6
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Publication
16484601 | J:119865
First Author: Zhang J
Year: 2006
Journal: Arterioscler Thromb Vasc Biol
Title: Generation of an adult smooth muscle cell-targeted Cre recombinase mouse model.
Volume: 26
Issue: 3
Pages: e23-4
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Publication
11158319 | J:67387
First Author: Zhang JC
Year: 2001
Journal: Mol Cell Biol
Title: Analysis of SM22alpha-deficient mice reveals unanticipated insights into smooth muscle cell differentiation and function.
Volume: 21
Issue: 4
Pages: 1336-44
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Publication
15044321 | J:97558
First Author: Feil S
Year: 2004
Journal: Circ Res
Title: SM22alpha modulates vascular smooth muscle cell phenotype during atherogenesis.
Volume: 94
Issue: 7
Pages: 863-5
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Publication
20428474 | J:160843
First Author: Yang M
Year: 2010
Journal: Int J Physiol Pathophysiol Pharmacol
Title: Sm22α transcription occurs at the early onset of the cardiovascular system and the intron 1 is dispensable for its transcription in smooth muscle cells during mouse development.
Volume: 2
Issue: 1
Pages: 12-9
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Publication
20224039 | J:172143
First Author: Shen J
Year: 2010
Journal: Circ Res
Title: Disruption of SM22 promotes inflammation after artery injury via nuclear factor kappaB activation.
Volume: 106
Issue: 8
Pages: 1351-62
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Publication
21183509 | J:186022
First Author: Shen J
Year: 2011
Journal: Cardiovasc Res
Title: Arterial injury promotes medial chondrogenesis in Sm22 knockout mice.
Volume: 90
Issue: 1
Pages: 28-37
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Publication
36758986 | J:353990
 
First Author: Wu X
Year: 2023
Journal: Eur Respir J
Title: Regulating the cell shift of endothelial cell-like myofibroblasts in pulmonary fibrosis.
Volume: 61
Issue: 6
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Publication
32819594 | J:302399
First Author: Gao Y
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Smooth muscle 22α deficiency impairs oxytocin-induced uterine contractility in mice at full-term pregnancy.
Volume: 529
Issue: 4
Pages: 884-889
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Publication
37897489 | J:348150
 
First Author: Huang J
Year: 2023
Journal: Endocrinology
Title: Adipocyte Subpopulations Mediate Growth Hormone-induced Lipolysis and Glucose Tolerance in Male Mice.
Volume: 164
Issue: 11
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Publication
23702880 | J:273494
First Author: Yoshida T
Year: 2013
Journal: J Am Heart Assoc
Title: Smooth muscle-selective inhibition of nuclear factor-κB attenuates smooth muscle phenotypic switching and neointima formation following vascular injury.
Volume: 2
Issue: 3
Pages: e000230
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Publication
37108281 | J:335259
 
First Author: Xu X
Year: 2023
Journal: Int J Mol Sci
Title: SM22α Deletion Contributes to Neurocognitive Impairment in Mice through Modulating Vascular Smooth Muscle Cell Phenotypes.
Volume: 24
Issue: 8
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Publication
27629412 | J:237265
First Author: Lv P
Year: 2016
Journal: Am J Physiol Cell Physiol
Title: SM22α inhibits lamellipodium formation and migration via Ras-Arp2/3 signaling in synthetic VSMCs.
Volume: 311
Issue: 5
Pages: C758-C767
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Publication
33859778 | J:316072
 
First Author: Lv P
Year: 2021
Journal: Oxid Med Cell Longev
Title: SM22α Loss Contributes to Apoptosis of Vascular Smooth Muscle Cells via Macrophage-Derived circRasGEF1B.
Volume: 2021
Pages: 5564884
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Publication
22469697 | J:184707
First Author: Daniel C
Year: 2012
Journal: Lab Invest
Title: Transgelin is a marker of repopulating mesangial cells after injury and promotes their proliferation and migration.
Volume: 92
Issue: 6
Pages: 812-26
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Publication
32616053 | J:304337
First Author: Zhang X
Year: 2020
Journal: J Exp Clin Cancer Res
Title: SM22α+ vascular mural cells are essential for vessel stability in tumors and undergo phenotype transition regulated by Notch signaling.
Volume: 39
Issue: 1
Pages: 124
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Publication
35762602 | J:329957
First Author: Ito R
Year: 2022
Journal: Am J Physiol Lung Cell Mol Physiol
Title: SM22α cell-specific HIF stabilization mitigates hyperoxia-induced neonatal lung injury.
Volume: 323
Issue: 2
Pages: L129-L141
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GXD Expression
GXD Expression
   
Probe: MGI:1934239
Assay Type: Western blot
Annotation Date: 2001-05-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672819
Stage: TS19
Assay Id: MGI:1934367
Age: embryonic day 11.5
Image: 1
Specimen Label: 11
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1934239
Assay Type: Western blot
Annotation Date: 2001-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672820
Stage: TS20
Assay Id: MGI:1934367
Age: embryonic day 12.5
Image: 1
Specimen Label: 12
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:1934239
Assay Type: Western blot
Annotation Date: 2001-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672821
Stage: TS21
Assay Id: MGI:1934367
Age: embryonic day 13.5
Image: 1
Specimen Label: 13
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:1934239
Assay Type: Western blot
Annotation Date: 2001-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672822
Stage: TS22
Assay Id: MGI:1934367
Age: embryonic day 14.5
Image: 1
Specimen Label: 14
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:1934239
Assay Type: Western blot
Annotation Date: 2001-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672823
Stage: TS23
Assay Id: MGI:1934367
Age: embryonic day 15.5
Image: 1
Specimen Label: 15
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:1934239
Assay Type: Western blot
Annotation Date: 2001-05-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:1934367
Age: postnatal
Image: 1
Specimen Label: *
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
       
Probe: MGI:3641063
Assay Type: RT-PCR
Annotation Date: 2006-08-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1860128
Stage: TS28
Assay Id: MGI:3641077
Age: postnatal adult
Specimen Label: Aorta
Specimen Num: 1
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GXD Expression
GXD Expression
       
Probe: MGI:3641063
Assay Type: RT-PCR
Annotation Date: 2006-08-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:3641077
Age: postnatal adult
Specimen Label: Bladder
Specimen Num: 2
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GXD Expression
GXD Expression
       
Probe: MGI:3641063
Assay Type: RT-PCR
Annotation Date: 2006-08-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3641077
Age: postnatal adult
Specimen Label: Brain
Specimen Num: 3
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GXD Expression
GXD Expression
       
Probe: MGI:3641063
Assay Type: RT-PCR
Annotation Date: 2006-08-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3641077
Age: postnatal adult
Specimen Label: Heart
Specimen Num: 4
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GXD Expression
GXD Expression
       
Probe: MGI:3641063
Assay Type: RT-PCR
Annotation Date: 2006-08-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3641077
Age: postnatal adult
Specimen Label: Kidney
Specimen Num: 5
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GXD Expression
GXD Expression
       
Probe: MGI:3641063
Assay Type: RT-PCR
Annotation Date: 2006-08-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3641077
Age: postnatal adult
Specimen Label: Liver
Specimen Num: 6
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GXD Expression
GXD Expression
       
Probe: MGI:3641063
Assay Type: RT-PCR
Annotation Date: 2006-08-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3641077
Age: postnatal adult
Specimen Label: Lung
Specimen Num: 7
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GXD Expression
GXD Expression
       
Probe: MGI:3641063
Assay Type: RT-PCR
Annotation Date: 2006-08-16
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3641077
Age: postnatal adult
Specimen Label: Sk. Muscle
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
       
Probe: MGI:3641063
Assay Type: RT-PCR
Annotation Date: 2006-08-16
Strength: Not Specified
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:3641077
Age: postnatal adult
Specimen Label: Uterus
Specimen Num: 9
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•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4820419
Assay Type: Western blot
Annotation Date: 2010-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1860128
Stage: TS28
Assay Id: MGI:4820420
Age: postnatal adult
Specimen Label: aorta +/+
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4820419
Assay Type: Western blot
Annotation Date: 2010-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1860128
Stage: TS28
Assay Id: MGI:4820420
Age: postnatal adult
Specimen Label: aorta +/-
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4820419
Assay Type: Western blot
Annotation Date: 2010-08-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1860128
Stage: TS28
Assay Id: MGI:4820420
Age: postnatal adult
Specimen Label: aorta -/-
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4820419
Assay Type: Western blot
Annotation Date: 2010-08-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:4820420
Age: postnatal adult
Specimen Label: bladder +/+
Detected: true
Specimen Num: 4
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•
•
•
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