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Search results 1 to 100 out of 1189 for Tagln

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0.039s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: Transgelin (TAGLN) belongs to the calponin family, whose members have a N-terminal calponin homology domain (CH) and a C-terminal calponin-like repeat. Transgelin (also known as SM22) is an actin binding protein localised to the cytoskeletal apparatus []. Transgelin is required in agonist-induced smooth muscle contraction and is involved in cell migration [, ]. It has tumour suppressive functions in certain cells [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression  
Probe: MGI:1054549
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2622022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825734
Age: embryonic day 14.5
Image: Additional file 4 Tagln
Detected: true
Specimen Num: 1
Publication
First Author: Malhowski AJ
Year: 2011
Journal: Hum Mol Genet
Title: Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
Volume: 20
Issue: 7
Pages: 1290-305
Publication
First Author: Fogelstrand P
Year: 2009
Journal: J Exp Med
Title: Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2).
Volume: 206
Issue: 11
Pages: 2397-406
Publication
First Author: Kühbandner S
Year: 2000
Journal: Genesis
Title: Temporally controlled somatic mutagenesis in smooth muscle.
Volume: 28
Issue: 1
Pages: 15-22
Publication
First Author: Shen D
Year: 2011
Journal: Circ Res
Title: Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells.
Volume: 109
Issue: 6
Pages: 616-28
Publication
First Author: Chen Z
Year: 2012
Journal: J Biol Chem
Title: DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice.
Volume: 287
Issue: 23
Pages: 19018-28
Publication
First Author: Mao X
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Vascular smooth muscle cell Smad4 gene is important for mouse vascular development.
Volume: 32
Issue: 9
Pages: 2171-7
Publication
First Author: Pan Y
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality.
Volume: 408
Issue: 3
Pages: 369-74
Publication
First Author: Frutkin AD
Year: 2006
Journal: J Mol Cell Cardiol
Title: A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre.
Volume: 41
Issue: 4
Pages: 724-31
Publication
First Author: Shen Z
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Smooth muscle protein 22 alpha-Cre is expressed in myeloid cells in mice.
Volume: 422
Issue: 4
Pages: 639-42
Publication
First Author: Majesky MW
Year: 2017
Journal: Circ Res
Title: Differentiated Smooth Muscle Cells Generate a Subpopulation of Resident Vascular Progenitor Cells in the Adventitia Regulated by Klf4.
Volume: 120
Issue: 2
Pages: 296-311
Publication
First Author: Sheen CR
Year: 2015
Journal: J Bone Miner Res
Title: Pathophysiological role of vascular smooth muscle alkaline phosphatase in medial artery calcification.
Volume: 30
Issue: 5
Pages: 824-36
Publication
First Author: Albinsson S
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function.
Volume: 30
Issue: 6
Pages: 1118-26
Publication
First Author: Moessler H
Year: 1996
Journal: Development
Title: The SM 22 promoter directs tissue-specific expression in arterial but not in venous or visceral smooth muscle cells in transgenic mice.
Volume: 122
Issue: 8
Pages: 2415-25
Publication
First Author: Wang Y
Year: 2014
Journal: Circ Res
Title: Deletion of yes-associated protein (YAP) specifically in cardiac and vascular smooth muscle cells reveals a crucial role for YAP in mouse cardiovascular development.
Volume: 114
Issue: 6
Pages: 957-65
Publication
First Author: Mancini ML
Year: 2009
Journal: Dev Dyn
Title: Endoglin plays distinct roles in vascular smooth muscle cell recruitment and regulation of arteriovenous identity during angiogenesis.
Volume: 238
Issue: 10
Pages: 2479-93
Publication
First Author: Wegener JW
Year: 2004
Journal: FASEB J
Title: An essential role of Cav1.2 L-type calcium channel for urinary bladder function.
Volume: 18
Issue: 10
Pages: 1159-61
Publication
First Author: Turlo KA
Year: 2010
Journal: Genetics
Title: When Cre-mediated recombination in mice does not result in protein loss.
Volume: 186
Issue: 3
Pages: 959-67
Publication
First Author: Qin X
Year: 2017
Journal: Gastroenterology
Title: Heterotrimeric G Stimulatory Protein α Subunit Is Required for Intestinal Smooth Muscle Contraction in Mice.
Volume: 152
Issue: 5
Pages: 1114-1125.e5
Publication
First Author: Jaffe M
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Transforming growth factor-β signaling in myogenic cells regulates vascular morphogenesis, differentiation, and matrix synthesis.
Volume: 32
Issue: 1
Pages: e1-11
Publication
First Author: Aldeiri B
Year: 2018
Journal: Sci Rep
Title: Abrogation of TGF-beta signalling in TAGLN expressing cells recapitulates Pentalogy of Cantrell in the mouse.
Volume: 8
Issue: 1
Pages: 3658
Publication  
First Author: Gong H
Year: 2019
Journal: J Mol Cell Cardiol
Title: Shp2 in myocytes is essential for cardiovascular and neointima development.
Volume: 137
Pages: 71-81
Publication  
First Author: Riascos-Bernal DF
Year: 2016
Journal: Nat Commun
Title: β-Catenin C-terminal signals suppress p53 and are essential for artery formation.
Volume: 7
Pages: 12389
Publication
First Author: Feng X
Year: 2010
Journal: Development
Title: Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion.
Volume: 137
Issue: 24
Pages: 4191-9
Publication
First Author: Proweller A
Year: 2006
Journal: Cancer Res
Title: Impaired notch signaling promotes de novo squamous cell carcinoma formation.
Volume: 66
Issue: 15
Pages: 7438-44
Publication
First Author: Zhang J
Year: 2006
Journal: Arterioscler Thromb Vasc Biol
Title: Generation of an adult smooth muscle cell-targeted Cre recombinase mouse model.
Volume: 26
Issue: 3
Pages: e23-4
Publication
First Author: Lv P
Year: 2016
Journal: Am J Physiol Cell Physiol
Title: SM22α inhibits lamellipodium formation and migration via Ras-Arp2/3 signaling in synthetic VSMCs.
Volume: 311
Issue: 5
Pages: C758-C767
Publication
First Author: Zadelaar SM
Year: 2006
Journal: Transgenic Res
Title: Local Cre-mediated gene recombination in vascular smooth muscle cells in mice.
Volume: 15
Issue: 1
Pages: 31-6
Publication
First Author: Yoshida T
Year: 2013
Journal: J Am Heart Assoc
Title: Smooth muscle-selective inhibition of nuclear factor-κB attenuates smooth muscle phenotypic switching and neointima formation following vascular injury.
Volume: 2
Issue: 3
Pages: e000230
Publication
First Author: Feil S
Year: 2004
Journal: Circ Res
Title: SM22alpha modulates vascular smooth muscle cell phenotype during atherogenesis.
Volume: 94
Issue: 7
Pages: 863-5
Publication
First Author: Ivins S
Year: 2015
Journal: Dev Cell
Title: The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development.
Volume: 33
Issue: 4
Pages: 455-68
Publication
First Author: Wen T
Year: 2019
Journal: Cell Death Differ
Title: Transcription factor TEAD1 is essential for vascular development by promoting vascular smooth muscle differentiation.
Volume: 26
Issue: 12
Pages: 2790-2806
Publication
First Author: Turlo KA
Year: 2012
Journal: Dev Biol
Title: An essential requirement for β1 integrin in the assembly of extracellular matrix proteins within the vascular wall.
Volume: 365
Issue: 1
Pages: 23-35
Publication
First Author: Turner CJ
Year: 2015
Journal: Development
Title: α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo.
Volume: 142
Issue: 4
Pages: 797-808
Publication
First Author: French WJ
Year: 2008
Journal: Mol Cell Biol
Title: Platelet-derived growth factor receptors direct vascular development independent of vascular smooth muscle cell function.
Volume: 28
Issue: 18
Pages: 5646-57
Publication
First Author: Lewandowski SL
Year: 2015
Journal: J Biol Chem
Title: Histone Deacetylase 3 Coordinates Deacetylase-independent Epigenetic Silencing of Transforming Growth Factor-β1 (TGF-β1) to Orchestrate Second Heart Field Development.
Volume: 290
Issue: 45
Pages: 27067-89
Publication
First Author: Cohen ED
Year: 2009
Journal: J Clin Invest
Title: Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway.
Volume: 119
Issue: 9
Pages: 2538-49
Publication
First Author: Huang J
Year: 2010
Journal: Circ Res
Title: Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression.
Volume: 106
Issue: 3
Pages: 583-92
Publication
First Author: Wang Y
Year: 2017
Journal: Nat Commun
Title: Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.
Volume: 8
Issue: 1
Pages: 578
Publication
First Author: High FA
Year: 2007
Journal: J Clin Invest
Title: An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.
Volume: 117
Issue: 2
Pages: 353-63
Publication
First Author: Greif DM
Year: 2012
Journal: Dev Cell
Title: Radial construction of an arterial wall.
Volume: 23
Issue: 3
Pages: 482-93
Publication      
First Author: Genetic Resource Science at The Jackson Laboratory
Year: 2013
Journal: Direct Data Submission from Genetic Resource Science
Title: Expression/Specificity Patterns of Cre Alleles, 2013
Publication
First Author: He WQ
Year: 2008
Journal: Gastroenterology
Title: Myosin light chain kinase is central to smooth muscle contraction and required for gastrointestinal motility in mice.
Volume: 135
Issue: 2
Pages: 610-20
Publication
First Author: Zhang WC
Year: 2010
Journal: J Biol Chem
Title: Myosin light chain kinase is necessary for tonic airway smooth muscle contraction.
Volume: 285
Issue: 8
Pages: 5522-31
Publication
First Author: Moosmang S
Year: 2003
Journal: EMBO J
Title: Dominant role of smooth muscle L-type calcium channel Cav1.2 for blood pressure regulation.
Volume: 22
Issue: 22
Pages: 6027-34
Publication
First Author: Yin KJ
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Vascular PPARδ protects against stroke-induced brain injury.
Volume: 31
Issue: 3
Pages: 574-81
Publication
First Author: Buchholz BM
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Myocyte TLR4 enhances enteric and systemic inflammation driving late murine endotoxic ileus.
Volume: 308
Issue: 10
Pages: G852-62
Publication  
First Author: Yang H
Year: 2020
Journal: J Mol Cell Cardiol
Title: Abnormal Ca2+ handling contributes to the impairment of aortic smooth muscle contractility in Zucker diabetic fatty rats.
Volume: 141
Pages: 82-92
Publication
First Author: Yin M
Year: 2019
Journal: Cell Rep
Title: CD34+KLF4+ Stromal Stem Cells Contribute to Endometrial Regeneration and Repair.
Volume: 27
Issue: 9
Pages: 2709-2724.e3
Publication
First Author: Wolf E
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Vascular type 1 angiotensin receptors control blood pressure by augmenting peripheral vascular resistance in female mice.
Volume: 315
Issue: 4
Pages: F997-F1005
Publication  
First Author: Zhao Y
Year: 2016
Journal: Sci Rep
Title: XBP1 splicing triggers miR-150 transfer from smooth muscle cells to endothelial cells via extracellular vesicles.
Volume: 6
Pages: 28627
Publication
First Author: He WQ
Year: 2011
Journal: Am J Physiol Heart Circ Physiol
Title: Role of myosin light chain kinase in regulation of basal blood pressure and maintenance of salt-induced hypertension.
Volume: 301
Issue: 2
Pages: H584-91
Publication
First Author: Wang L
Year: 2010
Journal: Am J Hum Genet
Title: Mutations in myosin light chain kinase cause familial aortic dissections.
Volume: 87
Issue: 5
Pages: 701-7
Publication
First Author: Bhat OM
Year: 2020
Journal: Sci Rep
Title: Arterial Medial Calcification through Enhanced small Extracellular Vesicle Release in Smooth Muscle-Specific Asah1 Gene Knockout Mice.
Volume: 10
Issue: 1
Pages: 1645
Publication
First Author: Yao Y
Year: 2015
Journal: Cell Mol Life Sci
Title: The cellular origin of laminin determines its role in blood pressure regulation.
Volume: 72
Issue: 5
Pages: 999-1008
Publication
First Author: Sparks MA
Year: 2013
Journal: Hypertension
Title: Thromboxane receptors in smooth muscle promote hypertension, vascular remodeling, and sudden death.
Volume: 61
Issue: 1
Pages: 166-73
Publication
First Author: Bielenberg DR
Year: 2012
Journal: Am J Pathol
Title: Increased smooth muscle contractility in mice deficient for neuropilin 2.
Volume: 181
Issue: 2
Pages: 548-59
Publication
First Author: Essin K
Year: 2007
Journal: J Physiol
Title: Indirect coupling between Cav1.2 channels and ryanodine receptors to generate Ca2+ sparks in murine arterial smooth muscle cells.
Volume: 584
Issue: Pt 1
Pages: 205-19
Publication
First Author: Fernández-Tenorio M
Year: 2010
Journal: Circ Res
Title: Short communication: genetic ablation of L-type Ca2+ channels abolishes depolarization-induced Ca2+ release in arterial smooth muscle.
Volume: 106
Issue: 7
Pages: 1285-9
Publication
First Author: Moosmang S
Year: 2006
Journal: Circ Res
Title: Antihypertensive effects of the putative T-type calcium channel antagonist mibefradil are mediated by the L-type calcium channel Cav1.2.
Volume: 98
Issue: 1
Pages: 105-10
Publication
First Author: Liu G
Year: 2015
Journal: Am J Physiol Cell Physiol
Title: Bladder function in mice with inducible smooth muscle-specific deletion of the manganese superoxide dismutase gene.
Volume: 309
Issue: 3
Pages: C169-78
Publication
First Author: Elrashidy RA
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Smooth muscle-specific deletion of MnSOD exacerbates diabetes-induced bladder dysfunction in mice.
Volume: 317
Issue: 4
Pages: F906-F912
Publication
First Author: Wegener JW
Year: 2006
Journal: FASEB J
Title: Control of intestinal motility by the Ca(v)1.2 L-type calcium channel in mice.
Volume: 20
Issue: 8
Pages: 1260-2
Publication
First Author: Katajisto P
Year: 2008
Journal: Nat Genet
Title: LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis.
Volume: 40
Issue: 4
Pages: 455-9
Publication
First Author: Galmiche G
Year: 2013
Journal: Circ Res
Title: Inactivation of serum response factor contributes to decrease vascular muscular tone and arterial stiffness in mice.
Volume: 112
Issue: 7
Pages: 1035-45
Publication
First Author: Mericskay M
Year: 2007
Journal: Gastroenterology
Title: Inducible mouse model of chronic intestinal pseudo-obstruction by smooth muscle-specific inactivation of the SRF gene.
Volume: 133
Issue: 6
Pages: 1960-70
Publication
First Author: Fry JL
Year: 2016
Journal: Hypertension
Title: Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic Stiffness.
Volume: 68
Issue: 3
Pages: 775-84
Publication
First Author: Angstenberger M
Year: 2007
Journal: Gastroenterology
Title: Severe intestinal obstruction on induced smooth muscle-specific ablation of the transcription factor SRF in adult mice.
Volume: 133
Issue: 6
Pages: 1948-59
Publication
First Author: Feil S
Year: 2014
Journal: Circ Res
Title: Transdifferentiation of vascular smooth muscle cells to macrophage-like cells during atherogenesis.
Volume: 115
Issue: 7
Pages: 662-7
Publication
First Author: McGowan SE
Year: 2014
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Regulation of fibroblast lipid storage and myofibroblast phenotypes during alveolar septation in mice.
Volume: 307
Issue: 8
Pages: L618-31
Publication
First Author: McGowan SE
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Fibroblast growth factor signaling in myofibroblasts differs from lipofibroblasts during alveolar septation in mice.
Volume: 309
Issue: 5
Pages: L463-74
Publication
First Author: Lutshumba J
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Deletion of BMAL1 in Smooth Muscle Cells Protects Mice From Abdominal Aortic Aneurysms.
Volume: 38
Issue: 5
Pages: 1063-1075
Publication
First Author: Shu YN
Year: 2017
Journal: Cardiovasc Res
Title: CKII-SIRT1-SM22α loop evokes a self-limited inflammatory response in vascular smooth muscle cells.
Volume: 113
Issue: 10
Pages: 1198-1207
Publication
First Author: Ding X
Year: 2019
Journal: J Am Heart Assoc
Title: Nucleotide-Binding Oligomerization Domain-Like Receptor Protein 3 Deficiency in Vascular Smooth Muscle Cells Prevents Arteriovenous Fistula Failure Despite Chronic Kidney Disease.
Volume: 8
Issue: 1
Pages: e011211
Publication
First Author: Qi W
Year: 2017
Journal: Diabetologia
Title: SHP-1 activation inhibits vascular smooth muscle cell proliferation and intimal hyperplasia in a rodent model of insulin resistance and diabetes.
Volume: 60
Issue: 3
Pages: 585-596
Publication
First Author: Liu Y
Year: 2016
Journal: J Exp Med
Title: Calorie restriction protects against experimental abdominal aortic aneurysms in mice.
Volume: 213
Issue: 11
Pages: 2473-2488
Publication
First Author: Rahman A
Year: 2014
Journal: J Physiol
Title: The small GTPase Rac1 is required for smooth muscle contraction.
Volume: 592
Issue: 5
Pages: 915-26
Publication  
First Author: Gautam J
Year: 2016
Journal: Sci Rep
Title: The role of pericytic laminin in blood brain barrier integrity maintenance.
Volume: 6
Pages: 36450
Publication
First Author: Mancarella S
Year: 2013
Journal: FASEB J
Title: Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle.
Volume: 27
Issue: 3
Pages: 893-906
Publication
First Author: de Cárcer G
Year: 2017
Journal: Nat Med
Title: Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis.
Volume: 23
Issue: 8
Pages: 964-974
Publication
First Author: Döring B
Year: 2006
Journal: J Cell Sci
Title: Ablation of connexin43 in uterine smooth muscle cells of the mouse causes delayed parturition.
Volume: 119
Issue: Pt 9
Pages: 1715-22
Publication
First Author: Dumas SJ
Year: 2018
Journal: Circulation
Title: NMDA-Type Glutamate Receptor Activation Promotes Vascular Remodeling and Pulmonary Arterial Hypertension.
Volume: 137
Issue: 22
Pages: 2371-2389
Publication
First Author: Hamblin M
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Vascular smooth muscle cell peroxisome proliferator-activated receptor-γ mediates pioglitazone-reduced vascular lesion formation.
Volume: 31
Issue: 2
Pages: 352-9
Publication
First Author: Chang L
Year: 2012
Journal: Circulation
Title: Loss of perivascular adipose tissue on peroxisome proliferator-activated receptor-γ deletion in smooth muscle cells impairs intravascular thermoregulation and enhances atherosclerosis.
Volume: 126
Issue: 9
Pages: 1067-78
Publication
First Author: Tamura Y
Year: 2018
Journal: J Clin Invest
Title: Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension.
Volume: 128
Issue: 5
Pages: 1956-1970
Publication
First Author: Fan G
Year: 2020
Journal: Aging Cell
Title: Age attenuates the T-type CaV 3.2-RyR axis in vascular smooth muscle.
Volume: 19
Issue: 4
Pages: e13134
Publication
First Author: Sparks MA
Year: 2015
Journal: J Am Soc Nephrol
Title: Vascular Type 1A Angiotensin II Receptors Control BP by Regulating Renal Blood Flow and Urinary Sodium Excretion.
Volume: 26
Issue: 12
Pages: 2953-62
Publication    
First Author: Angbohang A
Year: 2021
Journal: J Biol Chem
Title: X-box binding protein 1-mediated COL4A1s secretion regulates communication between vascular smooth muscle and stem/progenitor cells.
Pages: 100541
Publication
First Author: Zhou AX
Year: 2015
Journal: Circ Res
Title: C/EBP-Homologous Protein (CHOP) in Vascular Smooth Muscle Cells Regulates Their Proliferation in Aortic Explants and Atherosclerotic Lesions.
Volume: 116
Issue: 11
Pages: 1736-43
Publication  
First Author: Li H
Year: 2019
Journal: J Mol Cell Cardiol
Title: Smooth muscle-specific LKB1 deletion exaggerates angiotensin II-induced abdominal aortic aneurysm in mice.
Volume: 130
Pages: 131-139
Publication
First Author: Wegener JW
Year: 2014
Journal: FASEB J
Title: Phospholipase D1 is involved in α1-adrenergic contraction of murine vascular smooth muscle.
Volume: 28
Issue: 3
Pages: 1044-8
Publication
First Author: Fry JL
Year: 2015
Journal: J Am Heart Assoc
Title: Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II-Induced Hypertension.
Volume: 4
Issue: 9
Pages: e002384
Publication
First Author: McGowan SE
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Neuropilin-1 and platelet-derived growth factor receptors cooperatively regulate intermediate filaments and mesenchymal cell migration during alveolar septation.
Volume: 315
Issue: 1
Pages: L102-L115
Publication
First Author: Chen HZ
Year: 2016
Journal: Circ Res
Title: Age-Associated Sirtuin 1 Reduction in Vascular Smooth Muscle Links Vascular Senescence and Inflammation to Abdominal Aortic Aneurysm.
Volume: 119
Issue: 10
Pages: 1076-1088
Publication
First Author: McGowan SE
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Platelet-derived growth factor receptor-α and Ras-related C3 botulinum toxin substrate-1 regulate mechano-responsiveness of lung fibroblasts.
Volume: 313
Issue: 6
Pages: L1174-L1187