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Search results 1 to 100 out of 272 for Tank

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
10010 | TANK
Type: gene
Organism: human
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Gene
459685 | TANK
Type: gene
Organism: chimpanzee
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Gene
539513 | TANK
Type: gene
Organism: cattle
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Gene
424190 | TANK
Type: gene
Organism: chicken
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Gene
767660 | tank
Type: gene
Organism: zebrafish
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Gene
700942 | TANK
Type: gene
Organism: macaque, rhesus
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Gene
100486218 | tank
Type: gene
Organism: frog, western clawed
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Gene
252961 | Tank
Type: gene
Organism: rat
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Gene
608092 | TANK
Type: gene
Organism: dog, domestic
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Protein Domain
IPR039669 | TANK
Type: Family
Description: TANK-binding kinase 1 (TBK1) and inducible IkappaB-kinase (IKK) are central regulators of type-I interferon induction. TANK (TRAF family member-associated NF-kappa-B activator) is aadaptor protein that connects IKK complexes with IKK epsilon and TBK1 kinases [, ]. It negatively regulates NF-kappaB activation by DNA damage via inhibiting ubiquitination of TRAF6 []. It is also a negative regulator of osteoclastogenesis and bone formation [].
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Protein Coding Gene
MGI:107676 | Tank
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22773835 | J:190237
First Author: Maruyama K
Year: 2012
Journal: J Biol Chem
Title: TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation.
Volume: 287
Issue: 34
Pages: 29114-24
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Protein
Q05BS9
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: true
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Protein
Q8R383
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
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Gene
29110 | TBK1
Type: gene
Organism: human
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Gene
105373719 | TANK-AS1
Type: gene
Organism: human
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Publication
34819357 | J:320014
 
First Author: Wakabayashi A
Year: 2022
Journal: Life Sci Alliance
Title: TANK prevents IFN-dependent fatal diffuse alveolar hemorrhage by suppressing DNA-cGAS aggregation.
Volume: 5
Issue: 2
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Publication
12133833 | -
First Author: Chariot A
Year: 2002
Journal: J Biol Chem
Title: Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases.
Volume: 277
Issue: 40
Pages: 37029-36
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Publication
30721969 | J:272511
First Author: Müller CP
Year: 2019
Journal: Cereb Cortex
Title: The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study.
Volume: 29
Issue: 4
Pages: 1736-1751
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Publication
34540911 | J:310845
 
First Author: Pang Y
Year: 2021
Journal: Front Cardiovasc Med
Title: TANK Promotes Pressure Overload Induced Cardiac Hypertrophy via Activating AKT Signaling Pathway.
Volume: 8
Pages: 687540
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Publication
21949249 | J:177337
First Author: Clark K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling.
Volume: 108
Issue: 41
Pages: 17093-8
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Publication
10581243 | J:66310
First Author: Pomerantz JL
Year: 1999
Journal: EMBO J
Title: NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase.
Volume: 18
Issue: 23
Pages: 6694-704
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Publication
19668221 | J:151757
First Author: Kawagoe T
Year: 2009
Journal: Nat Immunol
Title: TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis.
Volume: 10
Issue: 9
Pages: 965-72
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Publication
17507294 | J:129859
First Author: Tank J
Year: 2007
Journal: Auton Neurosci
Title: Sympathetic nerve traffic and circulating norepinephrine levels in RGS2-deficient mice.
Volume: 136
Issue: 1-2
Pages: 52-7
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Publication
25428949 | J:228849
 
First Author: Tank J
Year: 2014
Journal: Physiol Rep
Title: Preserved functional autonomic phenotype in adult mice overexpressing moderate levels of human alpha-synuclein in oligodendrocytes.
Volume: 2
Issue: 11
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Publication
25861989 | -
First Author: Wang W
Year: 2015
Journal: J Biol Chem
Title: TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase.
Volume: 290
Issue: 21
Pages: 13372-85
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Protein
A2AR78
Organism: Mus musculus/domesticus
Length: 360  
Fragment?: false
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Publication
21931631 | -
First Author: Goncalves A
Year: 2011
Journal: PLoS One
Title: Functional dissection of the TBK1 molecular network.
Volume: 6
Issue: 9
Pages: e23971
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Protein
P70347
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: false
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Protein
Q8C2D3
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
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Protein
Q3UGW0
Organism: Mus musculus/domesticus
Length: 414  
Fragment?: false
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Protein
Q3TNB4
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
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Protein
A2AR76
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
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Allele
Map4k4<m1Btlr> | MGI:7549174
 
Name: mitogen-activated protein kinase kinase kinase kinase 4; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
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Publication
8608943 | J:35327
First Author: Cheng G
Year: 1996
Journal: Genes Dev
Title: TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation.
Volume: 10
Issue: 8
Pages: 963-73
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Publication
17327220 | J:121134
First Author: Guo B
Year: 2007
Journal: J Biol Chem
Title: Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK.
Volume: 282
Issue: 16
Pages: 11817-26
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Publication
23201825 | J:194184
 
First Author: Salerno KM
Year: 2013
Journal: Neuroscience
Title: TRAF family member-associated NF-kappa B activator (TANK) expression increases in injured sensory neurons and is transcriptionally regulated by Sox11.
Volume: 231
Pages: 28-37
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Gene
481145 | TBK1
Type: gene
Organism: dog, domestic
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Gene
452047 | TBK1
Type: gene
Organism: chimpanzee
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Gene
533141 | TBK1
Type: gene
Organism: cattle
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Gene
417825 | TBK1
Type: gene
Organism: chicken
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Gene
717427 | TBK1
Type: gene
Organism: macaque, rhesus
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Gene
100216212 | tbk1
Type: gene
Organism: frog, western clawed
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Publication
28159912 | J:246386
First Author: Bakshi S
Year: 2017
Journal: Biochem J
Title: Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β.
Volume: 474
Issue: 7
Pages: 1163-1174
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Protein Coding Gene
MGP_CAROLIEiJ_G0023587 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025765 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025741 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025736 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025497 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_107676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026183 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025477 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025608 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025570 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025696 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026240 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025038 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024509 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 20
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•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 21
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•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 22
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•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 23
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•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1742828
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 24
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•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3288928
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 25
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•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 26
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•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1775128
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 27
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•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1683328
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 28
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•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1788628
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 29
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GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1789128
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 30
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1885228
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 31
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1866628
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 32
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 33
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3519728
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 34
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3515128
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 35
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3528528
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 36
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:1205322
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3514028
Stage: TS28
Assay Id: MGI:1205324
Age: postnatal week 6-8
Image: st96_465
Specimen Label: None
Detected: true
Specimen Num: 37
•
•
•
•
•




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