Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Lier N |
Year: |
2012 |
Journal: |
Histochem Cell Biol |
Title: |
Immunofluorescent localization of the Rab-GAP protein TBC1D4 (AS160) in mouse kidney. |
Volume: |
138 |
Issue: |
1 |
Pages: |
101-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Larsen JK |
Year: |
2022 |
Journal: |
Diabetes |
Title: |
Illumination of the Endogenous Insulin-Regulated TBC1D4 Interactome in Human Skeletal Muscle. |
Volume: |
71 |
Issue: |
5 |
Pages: |
906-920 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kjøbsted R |
Year: |
2019 |
Journal: |
Diabetes |
Title: |
TBC1D4 Is Necessary for Enhancing Muscle Insulin Sensitivity in Response to AICAR and Contraction. |
Volume: |
68 |
Issue: |
9 |
Pages: |
1756-1766 |
|
•
•
•
•
•
|
Publication |
First Author: |
Treebak JT |
Year: |
2010 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle. |
Volume: |
298 |
Issue: |
2 |
Pages: |
C377-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chadt A |
Year: |
2015 |
Journal: |
Diabetes |
Title: |
“Deletion of both Rab-GTPase–activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport [corrected]. |
Volume: |
64 |
Issue: |
3 |
Pages: |
746-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Benninghoff T |
Year: |
2020 |
Journal: |
Diabetes |
Title: |
The RabGAPs TBC1D1 and TBC1D4 Control Uptake of Long-Chain Fatty Acids Into Skeletal Muscle via Fatty Acid Transporter SLC27A4/FATP4. |
Volume: |
69 |
Issue: |
11 |
Pages: |
2281-2293 |
|
•
•
•
•
•
|
Publication |
First Author: |
Di Chiara M |
Year: |
2015 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney. |
Volume: |
309 |
Issue: |
9 |
Pages: |
F779-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sáinz N |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Leptin reduces the expression and increases the phosphorylation of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4 in muscle of ob/ob mice. |
Volume: |
7 |
Issue: |
1 |
Pages: |
e29389 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou Z |
Year: |
2017 |
Journal: |
FEBS Lett |
Title: |
Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking. |
Volume: |
591 |
Issue: |
1 |
Pages: |
88-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Wendt C |
Year: |
2021 |
Journal: |
Diabetes |
Title: |
Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. |
Volume: |
70 |
Issue: |
12 |
Pages: |
2796-2809 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Bouzakri K |
Year: |
2008 |
Journal: |
Diabetes |
Title: |
Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells. |
Volume: |
57 |
Issue: |
5 |
Pages: |
1195-204 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang HY |
Year: |
2013 |
Journal: |
Biochem J |
Title: |
AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues. |
Volume: |
449 |
Issue: |
2 |
Pages: |
479-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alves DS |
Year: |
2015 |
Journal: |
J Am Soc Nephrol |
Title: |
Akt Substrate of 160 kD Regulates Na+,K+-ATPase Trafficking in Response to Energy Depletion and Renal Ischemia. |
Volume: |
26 |
Issue: |
11 |
Pages: |
2765-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen S |
Year: |
2011 |
Journal: |
Cell Metab |
Title: |
Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking. |
Volume: |
13 |
Issue: |
1 |
Pages: |
68-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kramer HF |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle. |
Volume: |
281 |
Issue: |
42 |
Pages: |
31478-85 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603910 |
|
Stage: |
TS10 |
Assay Id: |
MGI:3028435 |
Age: |
embryonic day 7.0 |
|
|
Specimen Label: |
e7 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603918 |
|
Stage: |
TS18 |
Assay Id: |
MGI:3028435 |
Age: |
embryonic day 11.0 |
|
|
Specimen Label: |
11 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603923 |
|
Stage: |
TS23 |
Assay Id: |
MGI:3028435 |
Age: |
embryonic day 15.0 |
|
|
Specimen Label: |
15 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603925 |
|
Stage: |
TS25 |
Assay Id: |
MGI:3028435 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
17 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3028435 |
Age: |
postnatal adult |
|
|
Specimen Label: |
hrt |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3028435 |
Age: |
postnatal adult |
|
|
Specimen Label: |
brn |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3028435 |
Age: |
postnatal adult |
|
|
Specimen Label: |
spl |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3028435 |
Age: |
postnatal adult |
|
|
Specimen Label: |
lng |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3028435 |
Age: |
postnatal adult |
|
|
Specimen Label: |
lvr |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3598828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3028435 |
Age: |
postnatal adult |
|
|
Specimen Label: |
msl |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3028435 |
Age: |
postnatal adult |
|
|
Specimen Label: |
kid |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3027973 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-02-20 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3028435 |
Age: |
postnatal adult |
|
|
Specimen Label: |
tst |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1876728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803781 |
|
Specimen Label: |
JAX_1803781 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1737328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803787 |
Note: |
kidney |
Specimen Label: |
JAX_1803787 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1619828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803789 |
|
Specimen Label: |
JAX_1803789 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3267828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803780 |
|
Specimen Label: |
JAX_1803780 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1697428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803773 |
|
Specimen Label: |
JAX_1803773 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1778728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803778 |
|
Specimen Label: |
JAX_1803778 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1610528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803788 |
|
Specimen Label: |
JAX_1803788 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1842628 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803791 |
|
Specimen Label: |
JAX_1803791 |
Detected: |
true |
Specimen Num: |
21 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1685328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803785 |
|
Specimen Label: |
JAX_1803785 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1750328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803782 |
|
Specimen Label: |
JAX_1803782 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803786 |
|
Specimen Label: |
JAX_1803786 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1876828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803772 |
|
Specimen Label: |
JAX_1803772 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1832128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803777 |
|
Specimen Label: |
JAX_1803777 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4428080 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:7540476 |
Age: |
embryonic day 14.5 |
|
Note: |
Caudal expression was greater than rostral. |
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1763128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803776 |
|
Specimen Label: |
JAX_1803776 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1929028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803774 |
|
Specimen Label: |
JAX_1803774 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3273028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803779 |
|
Specimen Label: |
JAX_1803779 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1757728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803784 |
|
Specimen Label: |
JAX_1803784 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2991528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803771 |
|
Specimen Label: |
JAX_1803771 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803790 |
|
Specimen Label: |
JAX_1803790 |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1881228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803770 |
|
Specimen Label: |
JAX_1803770 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1881228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692593 |
Age: |
postnatal adult |
Image: |
JAX_1803775 |
|
Specimen Label: |
JAX_1803775 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gridley S |
Year: |
2005 |
Journal: |
Cell Signal |
Title: |
Novel insulin-elicited phosphoproteins in adipocytes. |
Volume: |
17 |
Issue: |
1 |
Pages: |
59-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie B |
Year: |
2016 |
Journal: |
Diabetes |
Title: |
The Inactivation of RabGAP Function of AS160 Promotes Lysosomal Degradation of GLUT4 and Causes Postprandial Hyperglycemia and Hyperinsulinemia. |
Volume: |
65 |
Issue: |
11 |
Pages: |
3327-3340 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ducommun S |
Year: |
2012 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Thr649Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle. |
Volume: |
302 |
Issue: |
9 |
Pages: |
E1036-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stermann T |
Year: |
2018 |
Journal: |
Endocrinology |
Title: |
Deletion of the RabGAP TBC1D1 Leads to Enhanced Insulin Secretion and Fatty Acid Oxidation in Islets From Male Mice. |
Volume: |
159 |
Issue: |
4 |
Pages: |
1748-1761 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hargett SR |
Year: |
2016 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Rab GAPs AS160 and Tbc1d1 play nonredundant roles in the regulation of glucose and energy homeostasis in mice. |
Volume: |
310 |
Issue: |
4 |
Pages: |
E276-88 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
272
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Kramer HF |
Year: |
2006 |
Journal: |
Diabetes |
Title: |
Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle. |
Volume: |
55 |
Issue: |
7 |
Pages: |
2067-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lansey MN |
Year: |
2012 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis. |
Volume: |
303 |
Issue: |
10 |
Pages: |
E1273-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quan C |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart. |
Volume: |
10 |
Issue: |
4 |
Pages: |
e0124491 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kane S |
Year: |
2005 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Calmodulin binds to the Rab GTPase activating protein required for insulin-stimulated GLUT4 translocation. |
Volume: |
335 |
Issue: |
1 |
Pages: |
175-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eguez L |
Year: |
2005 |
Journal: |
Cell Metab |
Title: |
Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein. |
Volume: |
2 |
Issue: |
4 |
Pages: |
263-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim HY |
Year: |
2011 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Emerging role of Akt substrate protein AS160 in the regulation of AQP2 translocation. |
Volume: |
301 |
Issue: |
1 |
Pages: |
F151-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tan SX |
Year: |
2012 |
Journal: |
Mol Cell Biol |
Title: |
The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes. |
Volume: |
32 |
Issue: |
24 |
Pages: |
4946-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Treebak JT |
Year: |
2006 |
Journal: |
Diabetes |
Title: |
AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits. |
Volume: |
55 |
Issue: |
7 |
Pages: |
2051-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sano H |
Year: |
2007 |
Journal: |
Cell Metab |
Title: |
Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane. |
Volume: |
5 |
Issue: |
4 |
Pages: |
293-303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kusudo T |
Year: |
2011 |
Journal: |
Genes Cells |
Title: |
Fatty acid-binding protein 3 stimulates glucose uptake by facilitating AS160 phosphorylation in mouse muscle cells. |
Volume: |
16 |
Issue: |
6 |
Pages: |
681-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weimershaus M |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation. |
Volume: |
24 |
Issue: |
13 |
Pages: |
3568-3581 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chavez JA |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation. |
Volume: |
283 |
Issue: |
14 |
Pages: |
9187-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Balsevich G |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function. |
Volume: |
8 |
Issue: |
1 |
Pages: |
1725 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kislinger T |
Year: |
2006 |
Journal: |
Cell |
Title: |
Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling. |
Volume: |
125 |
Issue: |
1 |
Pages: |
173-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liang X |
Year: |
2010 |
Journal: |
Mol Biol Cell |
Title: |
AS160 modulates aldosterone-stimulated epithelial sodium channel forward trafficking. |
Volume: |
21 |
Issue: |
12 |
Pages: |
2024-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu L |
Year: |
2014 |
Journal: |
Dev Cell |
Title: |
Rab8a-AS160-MSS4 regulatory circuit controls lipid droplet fusion and growth. |
Volume: |
30 |
Issue: |
4 |
Pages: |
378-93 |
|
•
•
•
•
•
|