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Search results 1 to 100 out of 256 for Tbce

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0.069s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: Tubulin proteostasis is regulated by a group of molecular chaperones termed tubulin cofactors (TBC). This entry represents TBCE (tubulin-specific chaperone E), which is an alpha-tubulin binding protein that, together with Arl2 and cofactors D (TBCD), A (TBCA or p14), B (TBCB) and C (TBCC), participate in tubulin biogenesis []. TBCE contains an N-terminal cytoskeleton-associated protein with glycine-rich segment (CAP-Gly) domain, a leucine-rich repeat protein-protein interaction domain followed by leucine-rich repeat (LRR) domains, and a C-terminal ubiquitin-like (Ubl) domain [].Mutations in TBCE gene cause the Kenny-Caffey/Sanjad-Sakati syndrome, characterised by hypoparathyroidism, mental retardation and facial dysmorphism [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Parvari R
Year: 2002
Journal: Nat Genet
Title: Mutation of TBCE causes hypoparathyroidism-retardation-dysmorphism and autosomal recessive Kenny-Caffey syndrome.
Volume: 32
Issue: 3
Pages: 448-52
Publication
First Author: Serna M
Year: 2015
Journal: J Cell Sci
Title: The structure of the complex between α-tubulin, TBCE and TBCB reveals a tubulin dimer dissociation mechanism.
Volume: 128
Issue: 9
Pages: 1824-34
Publication
First Author: Martin N
Year: 2002
Journal: Nat Genet
Title: A missense mutation in Tbce causes progressive motor neuronopathy in mice.
Volume: 32
Issue: 3
Pages: 443-7
Publication
First Author: Schaefer MK
Year: 2007
Journal: J Neurosci
Title: Progressive motor neuronopathy: a critical role of the tubulin chaperone TBCE in axonal tubulin routing from the Golgi apparatus.
Volume: 27
Issue: 33
Pages: 8779-89
Publication  
First Author: Rak K
Year: 2013
Journal: Exp Neurol
Title: Mutation of the TBCE gene causes disturbance of microtubules in the auditory nerve and cochlear outer hair cell degeneration accompanied by progressive hearing loss in the pmn/pmn mouse.
Volume: 250
Pages: 333-40
Protein
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
Publication
First Author: Kortazar D
Year: 2007
Journal: Exp Cell Res
Title: Role of cofactors B (TBCB) and E (TBCE) in tubulin heterodimer dissociation.
Volume: 313
Issue: 3
Pages: 425-36
Protein
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 524  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
Publication  
First Author: Bieniussa L
Year: 2022
Journal: Front Neurol
Title: Pegylated Insulin-Like Growth Factor 1 attenuates Hair Cell Loss and promotes Presynaptic Maintenance of Medial Olivocochlear Cholinergic Fibers in the Cochlea of the Progressive Motor Neuropathy Mouse.
Volume: 13
Pages: 885026
Publication
First Author: Bommel H
Year: 2002
Journal: J Cell Biol
Title: Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease.
Volume: 159
Issue: 4
Pages: 563-9
Publication
First Author: Schmalbruch H
Year: 1991
Journal: J Neuropathol Exp Neurol
Title: A new mouse mutant with progressive motor neuronopathy.
Volume: 50
Issue: 3
Pages: 192-204
Publication
First Author: Sagot Y
Year: 1998
Journal: J Neurosci
Title: Differential effects of neurotrophic factors on motoneuron retrograde labeling in a murine model of motoneuron disease.
Volume: 18
Issue: 3
Pages: 1132-41
Publication
First Author: Kennel P
Year: 2000
Journal: J Neurol Sci
Title: Riluzole prolongs survival and delays muscle strength deterioration in mice with progressive motor neuronopathy (pmn).
Volume: 180
Issue: 1-2
Pages: 55-61
Publication
First Author: Duong F
Year: 1998
Journal: Br J Pharmacol
Title: The effect of the nonpeptide neurotrophic compound SR 57746A on the progression of the disease state of the pmn mouse.
Volume: 124
Issue: 4
Pages: 811-7
Publication
First Author: Kennel PF
Year: 1996
Journal: Neurobiol Dis
Title: Electromyographical and motor performance studies in the pmn mouse model of neurodegenerative disease.
Volume: 3
Issue: 2
Pages: 137-47
Publication  
First Author: Schmalbruch H
Year: 1990
Journal: Mouse Genome
Title: 'Progressive motor neuropathy' (pmn), a new neurological mutant in the mouse.
Volume: 87
Pages: 113
Publication
First Author: Bordet T
Year: 1999
Journal: J Clin Invest
Title: Adenoviral cardiotrophin-1 gene transfer protects pmn mice from progressive motor neuronopathy.
Volume: 104
Issue: 8
Pages: 1077-85
Publication
First Author: Sagot Y
Year: 1996
Journal: J Neurosci
Title: GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice.
Volume: 16
Issue: 7
Pages: 2335-41
Publication
First Author: Ferrer-Alcon M
Year: 2008
Journal: Neuroscience
Title: Low intensity exercise attenuates disease progression and stimulates cell proliferation in the spinal cord of a mouse model with progressive motor neuronopathy.
Volume: 152
Issue: 2
Pages: 291-5
Publication
First Author: Sendtner M
Year: 1992
Journal: Nature
Title: Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy.
Volume: 358
Issue: 6386
Pages: 502-4
Publication
First Author: Haase G
Year: 1997
Journal: Nat Med
Title: Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors.
Volume: 3
Issue: 4
Pages: 429-36
Publication
First Author: Jablonka S
Year: 2011
Journal: Exp Neurol
Title: Therapeutic effects of PEGylated insulin-like growth factor I in the pmn mouse model of motoneuron disease.
Volume: 232
Issue: 2
Pages: 261-9
Publication
First Author: Kretschmannová K
Year: 2004
Journal: Physiol Res
Title: Characterization of neuromuscular transmission in mice with progressive motoneuronopathy.
Volume: 53
Issue: 5
Pages: 541-8
Publication  
First Author: Haase G
Year: 1998
Journal: J Neurol Sci
Title: Adenovirus-mediated transfer of the neurotrophin-3 gene into skeletal muscle of pmn mice: therapeutic effects and mechanisms of action.
Volume: 160 Suppl 1
Pages: S97-105
Publication
First Author: Holtmann B
Year: 1999
Journal: J Neurol Sci
Title: Comparative analysis of motoneuron loss and functional deficits in PMN mice: implications for human motoneuron disease.
Volume: 169
Issue: 1-2
Pages: 140-7
Publication
First Author: Moos T
Year: 1995
Journal: J Neurocytol
Title: Increased accumulation of transferrin by motor neurons of the mouse mutant progressive motor neuronopathy (pmn/pmn).
Volume: 24
Issue: 5
Pages: 389-98
Publication
First Author: Sagot Y
Year: 1995
Journal: Eur J Neurosci
Title: Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse.
Volume: 7
Issue: 6
Pages: 1313-22
Publication
First Author: Ferrer-Alcon M
Year: 2007
Journal: Neuroreport
Title: Grafted neural stem cells increase the life span and protect motoneurons in pmn mice.
Volume: 18
Issue: 14
Pages: 1463-8
Publication
First Author: Simonin Y
Year: 2006
Journal: J Neurosci
Title: An inhibitor of serine proteases, neuroserpin, acts as a neuroprotective agent in a mouse model of neurodegenerative disease.
Volume: 26
Issue: 41
Pages: 10614-9
Publication
First Author: Ferri A
Year: 2003
Journal: Curr Biol
Title: Inhibiting axon degeneration and synapse loss attenuates apoptosis and disease progression in a mouse model of motoneuron disease.
Volume: 13
Issue: 8
Pages: 669-73
Publication
First Author: Simonin Y
Year: 2007
Journal: J Neurochem
Title: Axonal involvement in the Wlds neuroprotective effect: analysis of pure motoneurons in a mouse model protected from motor neuron disease at a pre-symptomatic age.
Volume: 101
Issue: 2
Pages: 530-42
Publication
First Author: Simonin Y
Year: 2007
Journal: Eur J Neurosci
Title: The neuroprotective effects of the WldS gene are correlated with proteasome expression rather than apoptosis.
Volume: 25
Issue: 8
Pages: 2269-74
Publication
First Author: Sagot Y
Year: 1995
Journal: J Neurosci
Title: Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease.
Volume: 15
Issue: 11
Pages: 7727-33
Publication
First Author: Bellouze S
Year: 2014
Journal: Hum Mol Genet
Title: Golgi fragmentation in pmn mice is due to a defective ARF1/TBCE cross-talk that coordinates COPI vesicle formation and tubulin polymerization.
Volume: 23
Issue: 22
Pages: 5961-75
Publication
First Author: Martin N
Year: 2001
Journal: Genomics
Title: Genetic and physical delineation of the region overlapping the progressive motor neuropathy (pmn) locus on mouse chromosome 13.
Volume: 75
Issue: 1-3
Pages: 9-16
Publication
First Author: Perrin FE
Year: 2006
Journal: J Neurochem
Title: Cell death pathways differ in several mouse models with motoneurone disease: analysis of pure motoneurone populations at a presymptomatic age.
Volume: 98
Issue: 6
Pages: 1959-72
Publication  
First Author: Ruiz M
Year: 2014
Journal: Neuropharmacology
Title: Neurodegenerative changes are prevented by Erythropoietin in the pmn model of motoneuron degeneration.
Volume: 83
Pages: 137-53
Publication
First Author: Sendtner M
Year: 1997
Journal: J Neurosci
Title: Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice.
Volume: 17
Issue: 18
Pages: 6999-7006
Publication
First Author: Efentakis P
Year: 2022
Journal: Eur Heart J
Title: Tubulin-folding cofactor E deficiency promotes vascular dysfunction by increased endoplasmic reticulum stress.
Volume: 43
Issue: 6
Pages: 488-500
Publication
First Author: Frey D
Year: 2000
Journal: J Neurosci
Title: Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases.
Volume: 20
Issue: 7
Pages: 2534-42
Publication
First Author: Selvaraj BT
Year: 2012
Journal: J Cell Biol
Title: Local axonal function of STAT3 rescues axon degeneration in the pmn model of motoneuron disease.
Volume: 199
Issue: 3
Pages: 437-51
Publication
First Author: Knudsen JG
Year: 2019
Journal: Cell Metab
Title: Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production.
Volume: 29
Issue: 2
Pages: 430-442.e4
Publication
First Author: Haenggeli C
Year: 2002
Journal: Neurosci Lett
Title: Differential vulnerability of cranial motoneurons in mouse models with motor neuron degeneration.
Volume: 335
Issue: 1
Pages: 39-43
Publication
First Author: Sedehizade F
Year: 1997
Journal: Muscle Nerve
Title: Expression of nerve-regulated genes in muscles of mouse mutants affected by spinal muscular atrophies and muscular dystrophies.
Volume: 20
Issue: 2
Pages: 186-94
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_07
Specimen Label: euxassay_004971_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_08
Specimen Label: euxassay_004971_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_09
Specimen Label: euxassay_004971_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_10
Specimen Label: euxassay_004971_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_12
Specimen Label: euxassay_004971_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_13
Specimen Label: euxassay_004971_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_14
Specimen Label: euxassay_004971_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_15
Specimen Label: euxassay_004971_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_05
Specimen Label: euxassay_004971_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_06
Specimen Label: euxassay_004971_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_07
Specimen Label: euxassay_004971_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_08
Specimen Label: euxassay_004971_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_09
Specimen Label: euxassay_004971_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_13
Specimen Label: euxassay_004971_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_14
Specimen Label: euxassay_004971_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_15
Specimen Label: euxassay_004971_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_16
Specimen Label: euxassay_004971_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_04
Specimen Label: euxassay_004971_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_05
Specimen Label: euxassay_004971_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_06
Specimen Label: euxassay_004971_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_07
Specimen Label: euxassay_004971_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_15
Specimen Label: euxassay_004971_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_16
Specimen Label: euxassay_004971_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:3140439
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4828613
Age: embryonic day 14.5
Image: euxassay_004971_17
Specimen Label: euxassay_004971_17
Detected: true
Specimen Num: 17