|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 924 for Tbp

<< First    < Previous  |  Next >    Last >>
0.022s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
6908 | TBP
Type: gene
Organism: human
•
•
•
•
•
Gene
549093 | tbp
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
key_31259 | TBP
Type: gene
Organism: hamster, golden
•
•
•
•
•
Gene
117526 | Tbp
Type: gene
Organism: rat
•
•
•
•
•
Gene
611193 | TBP
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
738472 | TBP
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
516578 | TBP
Type: gene
Organism: cattle
•
•
•
•
•
Gene
395995 | TBP
Type: gene
Organism: chicken
•
•
•
•
•
Gene
368882 | tbp
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
696258 | TBP
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Coding Gene
MGI:101838 | Tbp
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Domain
IPR000814 | TBP
Type: Family
Description: The TATA-box binding protein (TBP) is required for the initiation of transcription by RNA polymerases I, II and III, from promoters with or without a TATA box [, ]. TBP associates with a host of factors, including the general transcription factors SL1, TFIIA, -B, -D, -E, and -H, to form huge multi-subunit pre-initiation complexes on the core promoter. Through its association with different transcription factors, TBP can initiate transcription from different RNA polymerases. There are several related TBPs, including TBP-like (TBPL) proteins []. TBP binds directly to the TATA box promoter element, where it nucleates polymerase assembly, thus defining the transcription start site.The C-terminal core of TBP (~180 residues) is highly conserved and contains two 77-amino acid repeats that produce a saddle-shaped structure that straddles the DNA; this region binds to the TATA box and interacts with transcription factors and regulatory proteins []. By contrast, the N-terminal region varies in both length and sequence.
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3623381
Assay Type: RNA in situ
Annotation Date: 2006-05-26
Strength: Present
Sex: Female
Emaps: EMAPS:3562728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3623385
Age: postnatal adult
Image: 4B TBP
Specimen Label: 4B TBP
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3623381
Assay Type: RNA in situ
Annotation Date: 2006-05-26
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3623385
Age: postnatal adult
Image: 4B TBP
Specimen Label: 4B TBP
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5907637
Assay Type: RT-PCR
Annotation Date: 2017-08-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:5907669
Age: postnatal adult
Image: 4
Specimen Label: TBP
Detected: true
Specimen Num: 1
•
•
•
•
•
Protein
P29037
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: false
•
•
•
•
•
Publication
12878007 | -
First Author: Davidson I
Year: 2003
Journal: Trends Biochem Sci
Title: The genetics of TBP and TBP-related factors.
Volume: 28
Issue: 7
Pages: 391-8
•
•
•
•
•
Protein
E9Q084
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
•
•
•
•
•
Protein
P62340
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: false
•
•
•
•
•
Protein
Q8K073
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: false
•
•
•
•
•
Publication
10974559 | -
First Author: Pugh BF
Year: 2000
Journal: Gene
Title: Control of gene expression through regulation of the TATA-binding protein.
Volume: 255
Issue: 1
Pages: 1-14
•
•
•
•
•
Publication
12782648 | -
First Author: Hochheimer A
Year: 2003
Journal: Genes Dev
Title: Diversified transcription initiation complexes expand promoter selectivity and tissue-specific gene expression.
Volume: 17
Issue: 11
Pages: 1309-20
•
•
•
•
•
Protein
Q6SJ95
Organism: Mus musculus/domesticus
Length: 350  
Fragment?: false
•
•
•
•
•
Protein
Z4YMT0
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: true
•
•
•
•
•
Protein
B7ZMZ6
Organism: Mus musculus/domesticus
Length: 349  
Fragment?: false
•
•
•
•
•
Protein
Q6RI65
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: false
•
•
•
•
•
Protein
F8WJ67
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: true
•
•
•
•
•
Protein
A2T4N7
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: true
•
•
•
•
•
Protein
Q91YM5
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: false
•
•
•
•
•
Publication
1436073 | -
First Author: Nikolov DB
Year: 1992
Journal: Nature
Title: Crystal structure of TFIID TATA-box binding protein.
Volume: 360
Issue: 6399
Pages: 40-6
•
•
•
•
•
Publication
9027316 | J:38692
First Author: Mittal V
Year: 1997
Journal: Science
Title: Role for the amino-terminal region of human TBP in U6 snRNA transcription.
Volume: 275
Issue: 5303
Pages: 1136-40
•
•
•
•
•
Publication
8332475 | J:12850
First Author: Sumita K
Year: 1993
Journal: Nucleic Acids Res
Title: Structure of a mammalian TBP (TATA-binding protein) gene: isolation of the mouse TBP genome.
Volume: 21
Issue: 11
Pages: 2769
•
•
•
•
•
Publication
31612390 | J:293635
First Author: Zhao DM
Year: 2019
Journal: Curr Med Sci
Title: Role of Mutant TBP in Regulation of Myogenesis on Muscle Satellite Cells.
Volume: 39
Issue: 5
Pages: 734-740
•
•
•
•
•
Publication
29939130 | J:265882
   
First Author: Teves SS
Year: 2018
Journal: Elife
Title: A stable mode of bookmarking by TBP recruits RNA polymerase II to mitotic chromosomes.
Volume: 7
•
•
•
•
•
Publication
12150996 | J:77714
First Author: Hobbs NK
Year: 2002
Journal: Cell
Title: Removing the vertebrate-specific TBP N terminus disrupts placental beta2m-dependent interactions with the maternal immune system.
Volume: 110
Issue: 1
Pages: 43-54
•
•
•
•
•
Publication
11861477 | J:74970
First Author: Martianov I
Year: 2002
Journal: Development
Title: Distinct functions of TBP and TLF/TRF2 during spermatogenesis: requirement of TLF for heterochromatic chromocenter formation in haploid round spermatids.
Volume: 129
Issue: 4
Pages: 945-55
•
•
•
•
•
Protein
D3Z453
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: true
•
•
•
•
•
Protein
E9Q6D9
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: true
•
•
•
•
•
Protein
E9Q9Z7
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
•
•
•
•
•
Protein
Q6LEM2
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
•
•
•
•
•
Protein
C0LUL2
Organism: Mus musculus/domesticus
Length: 143  
Fragment?: false
•
•
•
•
•
Publication
17074809 | J:117728
First Author: Zhong S
Year: 2007
Journal: Mol Cell Biol
Title: TBP is differentially regulated by c-Jun N-terminal kinase 1 (JNK1) and JNK2 through Elk-1, controlling c-Jun expression and cell proliferation.
Volume: 27
Issue: 1
Pages: 54-64
•
•
•
•
•
Publication
17641088 | J:123297
First Author: Gazdag E
Year: 2007
Journal: Reproduction
Title: Analysis of TATA-binding protein 2 (TBP2) and TBP expression suggests different roles for the two proteins in regulation of gene expression during oogenesis and early mouse development.
Volume: 134
Issue: 1
Pages: 51-62
•
•
•
•
•
Gene
538929 | LOC538929
Type: gene
Organism: cattle
•
•
•
•
•
Publication
19515240 | J:151415
 
First Author: Pitulescu ME
Year: 2009
Journal: BMC Biochem
Title: TIPT2 and geminin interact with basal transcription factors to synergize in transcriptional regulation.
Volume: 10
Pages: 16
•
•
•
•
•
Publication
12411709 | J:79959
First Author: Martianov I
Year: 2002
Journal: Science
Title: RNA polymerase II transcription in murine cells lacking the TATA binding protein.
Volume: 298
Issue: 5595
Pages: 1036-9
•
•
•
•
•
Publication
8769130 | J:34974
First Author: Ohbayashi T
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Promoter structure of the mouse TATA-binding protein (TBP) gene.
Volume: 225
Issue: 1
Pages: 275-80
•
•
•
•
•
Publication
10648625 | J:60220
First Author: Oda T
Year: 2000
Journal: Mol Cell Biol
Title: A novel TATA-binding protein-binding protein, ABT1, activates basal transcription and has a yeast homolog that is essential for growth.
Volume: 20
Issue: 4
Pages: 1407-18
•
•
•
•
•
Publication
32107387 | J:286289
First Author: Liu Q
Year: 2020
Journal: Nat Commun
Title: Cerebellum-enriched protein INPP5A contributes to selective neuropathology in mouse model of spinocerebellar ataxias type 17.
Volume: 11
Issue: 1
Pages: 1101
•
•
•
•
•
Publication
22013162 | J:197741
First Author: Choukrallah MA
Year: 2012
Journal: Nucleic Acids Res
Title: Interconversion between active and inactive TATA-binding protein transcription complexes in the mouse genome.
Volume: 40
Issue: 4
Pages: 1446-59
•
•
•
•
•
Publication
9030607 | J:39160
First Author: Schmidt EE
Year: 1997
Journal: J Biol Chem
Title: Spermatid-specific overexpression of the TATA-binding protein gene involves recruitment of two potent testis-specific promoters.
Volume: 272
Issue: 8
Pages: 5326-34
•
•
•
•
•
Publication
29378605 | J:280119
First Author: Guo J
Year: 2018
Journal: Mol Neurodegener
Title: Piperine ameliorates SCA17 neuropathology by reducing ER stress.
Volume: 13
Issue: 1
Pages: 4
•
•
•
•
•
Publication
18218637 | J:135225
First Author: Friedman MJ
Year: 2008
Journal: J Biol Chem
Title: Polyglutamine expansion reduces the association of TATA-binding protein with DNA and induces DNA binding-independent neurotoxicity.
Volume: 283
Issue: 13
Pages: 8283-90
•
•
•
•
•
Publication
24462098 | J:213011
First Author: Yang S
Year: 2014
Journal: Neuron
Title: Age-dependent decrease in chaperone activity impairs MANF expression, leading to Purkinje cell degeneration in inducible SCA17 mice.
Volume: 81
Issue: 2
Pages: 349-65
•
•
•
•
•
Publication
12773572 | J:101819
First Author: Mohan WS Jr
Year: 2003
Journal: Mol Cell Biol
Title: TAF10 (TAF(II)30) is necessary for TFIID stability and early embryogenesis in mice.
Volume: 23
Issue: 12
Pages: 4307-18
•
•
•
•
•
Publication
9107673 | J:39622
First Author: Trachtulec Z
Year: 1997
Journal: Mamm Genome
Title: Isolation of candidate hybrid sterility 1 genes by cDNA selection in a 1.1 megabase pair region on mouse chromosome 17.
Volume: 8
Issue: 5
Pages: 312-6
•
•
•
•
•
Publication
26387956 | J:271036
First Author: Huang S
Year: 2015
Journal: Cell Rep
Title: Large Polyglutamine Repeats Cause Muscle Degeneration in SCA17 Mice.
Volume: 13
Issue: 1
Pages: 196-208
•
•
•
•
•
Publication
21419221 | J:173663
First Author: Wansleeben C
Year: 2011
Journal: Mech Dev
Title: An ENU-induced point mutation in the mouse Btaf1 gene causes post-gastrulation embryonic lethality and protein instability.
Volume: 128
Issue: 5-6
Pages: 279-88
•
•
•
•
•
Publication
26880551 | J:231014
   
First Author: Malecova B
Year: 2016
Journal: Elife
Title: TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells.
Volume: 5
•
•
•
•
•
Publication
12243750 | J:79204
First Author: Huang H
Year: 2002
Journal: Exp Cell Res
Title: Repression of transcription and interference with DNA binding of TATA-binding protein by C-terminal alternatively spliced p53.
Volume: 279
Issue: 2
Pages: 248-59
•
•
•
•
•
Publication
28821675 | J:248996
First Author: Yang Y
Year: 2017
Journal: J Neurosci
Title: Synergistic Toxicity of Polyglutamine-Expanded TATA-Binding Protein in Glia and Neuronal Cells: Therapeutic Implications for Spinocerebellar Ataxia 17.
Volume: 37
Issue: 38
Pages: 9101-9115
•
•
•
•
•
Publication
9286694 | J:42591
First Author: Trachtulec Z
Year: 1997
Journal: Genomics
Title: Linkage of TATA-binding protein and proteasome subunit C5 genes in mice and humans reveals synteny conserved between mammals and invertebrates.
Volume: 44
Issue: 1
Pages: 1-7
•
•
•
•
•
Publication
10441524 | J:56734
First Author: Aoki T
Year: 1999
Journal: Biochem Biophys Res Commun
Title: TIP120B: a novel TIP120-family protein that is expressed specifically in muscle tissues.
Volume: 261
Issue: 3
Pages: 911-6
•
•
•
•
•
Publication
8700832 | J:172495
First Author: Zhang H
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: A role for the Msx-1 homeodomain in transcriptional regulation: residues in the N-terminal arm mediate TATA binding protein interaction and transcriptional repression.
Volume: 93
Issue: 5
Pages: 1764-9
•
•
•
•
•
Publication
8835526 | J:31802
First Author: Gregorová S
Year: 1996
Journal: Mamm Genome
Title: Sub-milliMorgan map of the proximal part of mouse Chromosome 17 including the hybrid sterility 1 gene.
Volume: 7
Issue: 2
Pages: 107-13
•
•
•
•
•
Publication
11557891 | J:71679
First Author: Freiman RN
Year: 2001
Journal: Science
Title: Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development.
Volume: 293
Issue: 5537
Pages: 2084-7
•
•
•
•
•
Publication
16412700 | J:105948
First Author: Xiao L
Year: 2006
Journal: Gene Expr Patterns
Title: Developmental and cell type-specific regulation of core promoter transcription factors in germ cells of frogs and mice.
Volume: 6
Issue: 4
Pages: 409-19
•
•
•
•
•
Publication
9050847 | J:39012
First Author: Heix J
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1.
Volume: 94
Issue: 5
Pages: 1733-8
•
•
•
•
•
Publication
12471023 | J:81991
First Author: Schmidt EE
Year: 2003
Journal: J Biol Chem
Title: Fundamental cellular processes do not require vertebrate-specific sequences within the TATA-binding protein.
Volume: 278
Issue: 8
Pages: 6168-74
•
•
•
•
•
Publication
31167115 | J:278355
 
First Author: Moysés-Oliveira M
Year: 2019
Journal: Gene
Title: Search for appropriate reference genes for quantitative reverse transcription PCR studies in somite, prosencephalon and heart of early mouse embryo.
Volume: 710
Pages: 148-155
•
•
•
•
•
Publication
12665565 | J:83344
First Author: Pointud JC
Year: 2003
Journal: J Cell Sci
Title: The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.
Volume: 116
Issue: Pt 9
Pages: 1847-58
•
•
•
•
•
Publication
16522640 | J:112691
First Author: Prigge JR
Year: 2006
Journal: J Biol Chem
Title: Interaction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBP.
Volume: 281
Issue: 18
Pages: 12260-9
•
•
•
•
•
Publication
19752599 | J:156252
First Author: Svingen T
Year: 2009
Journal: Sex Dev
Title: Identification of suitable normalizing genes for quantitative real-time RT-PCR analysis of gene expression in fetal mouse gonads.
Volume: 3
Issue: 4
Pages: 194-204
•
•
•
•
•
Publication
21245044 | J:182882
First Author: Bottardi S
Year: 2011
Journal: Nucleic Acids Res
Title: Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation.
Volume: 39
Issue: 9
Pages: 3505-19
•
•
•
•
•
Publication
30094508 | J:266054
First Author: Barratt KS
Year: 2018
Journal: Mamm Genome
Title: Identification of reference genes suitable for RT-qPCR studies of murine gastrulation and patterning.
Volume: 29
Issue: 9-10
Pages: 656-662
•
•
•
•
•
Publication
14580349 | J:86236
First Author: Guermah M
Year: 2003
Journal: Mol Cell
Title: The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.
Volume: 12
Issue: 4
Pages: 991-1001
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0021096 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0023175 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0023141 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0023111 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0023141 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0022902 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_101838 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0023584 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0022419 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0022878 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0023011 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0022977 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0023085 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0023000 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0023620 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0022167 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0022478 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0023411 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0021997 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
1861978 | J:21431
First Author: Tamura T
Year: 1991
Journal: Nucleic Acids Res
Title: Striking homology of the 'variable' N-terminal as well as the 'conserved core' domains of the mouse and human TATA-factors (TFIID).
Volume: 19
Issue: 14
Pages: 3861-5
•
•
•
•
•
Publication
23665119 | J:198925
 
First Author: Portal E
Year: 2013
Journal: Behav Brain Res
Title: Automated home cage assessment shows behavioral changes in a transgenic mouse model of spinocerebellar ataxia type 17.
Volume: 250
Pages: 157-65
•
•
•
•
•
Publication
8359696 | J:14404
First Author: Danciger M
Year: 1993
Journal: Gene
Title: Transcription factor IID probes localize a single gene to the proximal region of mouse chromosome 17.
Volume: 130
Issue: 2
Pages: 283-6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:2660600
Assay Type: RT-PCR
Annotation Date: 2003-05-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:2660663
Age: embryonic day 8.5
Image: 4
Specimen Label: 8.5E +
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:2660600
Assay Type: RT-PCR
Annotation Date: 2003-05-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2660663
Age: postnatal adult
Image: 4
Specimen Label: 8.5d/p +
Detected: true
Specimen Num: 3
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom