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Search results 1 to 100 out of 934 for Tbx5

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0.022s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Nishimoto S
Year: 2015
Journal: Cell Rep
Title: RA Acts in a Coherent Feed-Forward Mechanism with Tbx5 to Control Limb Bud Induction and Initiation.
Volume: 12
Issue: 5
Pages: 879-91
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Bruneau BG
Year: 1999
Journal: Dev Biol
Title: Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome.
Volume: 211
Issue: 1
Pages: 100-8
Allele
Name: transgene insertion 1, Malcolm P Logan
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
GXD Expression    
Probe: MGI:6383138
Assay Type: RNA in situ
Annotation Date: 2020-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:6383160
Age: embryonic day 8.5
Image: 4 Tbx5 G4-/- G6-/-
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:6383138
Assay Type: RNA in situ
Annotation Date: 2020-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3799313
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:6383160
Age: embryonic day 8.5
Image: 4 Tbx5 G4+/+ G6+/+
Note: Predominantly expressed in primary heart field progenitor cells.
Detected: true
Specimen Num: 1
Publication
First Author: Hasson P
Year: 2007
Journal: Development
Title: Tbx5 is dispensable for forelimb outgrowth.
Volume: 134
Issue: 1
Pages: 85-92
Publication
First Author: Hiroi Y
Year: 2001
Journal: Nat Genet
Title: Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation.
Volume: 28
Issue: 3
Pages: 276-80
Publication
First Author: Lewandowski SL
Year: 2014
Journal: Hum Mol Genet
Title: Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis.
Volume: 23
Issue: 14
Pages: 3801-9
Publication
First Author: Sulaiman FA
Year: 2016
Journal: PLoS Genet
Title: Tbx5 Buffers Inherent Left/Right Asymmetry Ensuring Symmetric Forelimb Formation.
Volume: 12
Issue: 12
Pages: e1006521
Publication
First Author: Arnolds DE
Year: 2012
Journal: J Clin Invest
Title: TBX5 drives Scn5a expression to regulate cardiac conduction system function.
Volume: 122
Issue: 7
Pages: 2509-18
Publication
First Author: Xu H
Year: 2020
Journal: Hum Mol Genet
Title: Tbx5 inhibits hedgehog signaling in determination of digit identity.
Volume: 29
Issue: 9
Pages: 1405-1416
Publication
First Author: Rallis C
Year: 2003
Journal: Development
Title: Tbx5 is required for forelimb bud formation and continued outgrowth.
Volume: 130
Issue: 12
Pages: 2741-51
Publication
First Author: Liberatore CM
Year: 2000
Journal: Dev Biol
Title: Ventricular expression of tbx5 inhibits normal heart chamber development.
Volume: 223
Issue: 1
Pages: 169-80
Publication
First Author: Georges R
Year: 2008
Journal: Mol Cell Biol
Title: Distinct expression and function of alternatively spliced Tbx5 isoforms in cell growth and differentiation.
Volume: 28
Issue: 12
Pages: 4052-67
Publication
First Author: Takeuchi JK
Year: 2003
Journal: Development
Title: Tbx5 specifies the left/right ventricles and ventricular septum position during cardiogenesis.
Volume: 130
Issue: 24
Pages: 5953-64
Publication
First Author: Jeong HS
Year: 2015
Journal: Biochim Biophys Acta
Title: Fbxo25 controls Tbx5 and Nkx2-5 transcriptional activity to regulate cardiomyocyte development.
Volume: 1849
Issue: 6
Pages: 709-21
Publication
First Author: Miyao N
Year: 2020
Journal: PLoS One
Title: TBX5 R264K acts as a modifier to develop dilated cardiomyopathy in mice independently of T-box pathway.
Volume: 15
Issue: 4
Pages: e0227393
Publication
First Author: Cunningham TJ
Year: 2018
Journal: Cell Rep
Title: Genomic Knockout of Two Presumed Forelimb Tbx5 Enhancers Reveals They Are Nonessential for Limb Development.
Volume: 23
Issue: 11
Pages: 3146-3151
Publication
First Author: Waldron L
Year: 2016
Journal: Dev Cell
Title: The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation.
Volume: 36
Issue: 3
Pages: 262-75
Publication
First Author: Ng JK
Year: 2002
Journal: Development
Title: The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10.
Volume: 129
Issue: 22
Pages: 5161-70
Publication
First Author: Koshiba-Takeuchi K
Year: 2006
Journal: Nat Genet
Title: Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart.
Volume: 38
Issue: 2
Pages: 175-83
Publication
First Author: Diman NY
Year: 2014
Journal: Circ Res
Title: Tbx5 is required for avian and Mammalian epicardial formation and coronary vasculogenesis.
Volume: 115
Issue: 10
Pages: 834-44
Publication
First Author: Khan P
Year: 2002
Journal: Dev Biol
Title: Different regulation of T-box genes Tbx4 and Tbx5 during limb development and limb regeneration.
Volume: 250
Issue: 2
Pages: 383-92
Publication
First Author: Ghosh TK
Year: 2001
Journal: Hum Mol Genet
Title: Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome.
Volume: 10
Issue: 18
Pages: 1983-94
Publication
First Author: Hasson P
Year: 2010
Journal: Dev Cell
Title: Tbx4 and tbx5 acting in connective tissue are required for limb muscle and tendon patterning.
Volume: 18
Issue: 1
Pages: 148-56
Publication
First Author: Bickley SR
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Regulatory modulation of the T-box gene Tbx5 links development, evolution, and adaptation of the sternum.
Volume: 111
Issue: 50
Pages: 17917-22
Publication
First Author: Smemo S
Year: 2012
Journal: Hum Mol Genet
Title: Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease.
Volume: 21
Issue: 14
Pages: 3255-63
Publication
First Author: Puskaric S
Year: 2010
Journal: Hum Mol Genet
Title: Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart.
Volume: 19
Issue: 23
Pages: 4625-33
Publication
First Author: Plageman TF Jr
Year: 2004
Journal: J Biol Chem
Title: Differential expression and function of Tbx5 and Tbx20 in cardiac development.
Volume: 279
Issue: 18
Pages: 19026-34
Publication
First Author: Misra C
Year: 2014
Journal: Hum Mol Genet
Title: Disruption of myocardial Gata4 and Tbx5 results in defects in cardiomyocyte proliferation and atrioventricular septation.
Volume: 23
Issue: 19
Pages: 5025-35
Publication
First Author: Zhang Z
Year: 2019
Journal: Sci Rep
Title: Stoichiometric optimization of Gata4, Hand2, Mef2c, and Tbx5 expression for contractile cardiomyocyte reprogramming.
Volume: 9
Issue: 1
Pages: 14970
Publication
First Author: Maitra M
Year: 2009
Journal: Dev Biol
Title: Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development.
Volume: 326
Issue: 2
Pages: 368-77
Publication
First Author: Hoffmann AD
Year: 2014
Journal: PLoS Genet
Title: Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation.
Volume: 10
Issue: 10
Pages: e1004604
Publication
First Author: Minguillon C
Year: 2005
Journal: Dev Cell
Title: Tbx5 and Tbx4 are not sufficient to determine limb-specific morphologies but have common roles in initiating limb outgrowth.
Volume: 8
Issue: 1
Pages: 75-84
Publication
First Author: Arora R
Year: 2012
Journal: PLoS Genet
Title: Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system.
Volume: 8
Issue: 8
Pages: e1002866
Publication
First Author: Bruneau BG
Year: 2001
Journal: Cell
Title: A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.
Volume: 106
Issue: 6
Pages: 709-21
Publication
First Author: Moskowitz IP
Year: 2004
Journal: Development
Title: The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system.
Volume: 131
Issue: 16
Pages: 4107-16
Publication  
First Author: Polk RC
Year: 2015
Journal: BMC Dev Biol
Title: The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model.
Volume: 15
Pages: 30
Publication
First Author: Agarwal P
Year: 2003
Journal: Development
Title: Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo.
Volume: 130
Issue: 3
Pages: 623-33
Publication
First Author: Ding B
Year: 2006
Journal: J Biol Chem
Title: p204 is required for the differentiation of P19 murine embryonal carcinoma cells to beating cardiac myocytes: its expression is activated by the cardiac Gata4, Nkx2.5, and Tbx5 proteins.
Volume: 281
Issue: 21
Pages: 14882-92
Publication
First Author: Nishimoto S
Year: 2014
Journal: PLoS Genet
Title: A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity.
Volume: 10
Issue: 3
Pages: e1004245
Publication
First Author: Basson CT
Year: 1997
Journal: Nat Genet
Title: Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome.
Volume: 15
Issue: 1
Pages: 30-5
GXD Expression
Probe: MGI:1333201
Assay Type: RNA in situ
Annotation Date: 2009-06-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3846941
Age: embryonic day 10.5
Image: 1L
Note: Authors state that differential expression between Tbx4 and Tbx5 in limb mesenchyme is maintained.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1333201
Assay Type: RNA in situ
Annotation Date: 2009-06-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1677917
Stage: TS17
Assay Id: MGI:3846941
Age: embryonic day 10.5
Image: 1L
Note: Authors state that differential expression between Tbx4 and Tbx5 in limb mesenchyme is maintained.
Detected: false
Specimen Num: 2
Publication
First Author: Agulnik SI
Year: 1996
Journal: Genetics
Title: Evolution of mouse T-box genes by tandem duplication and cluster dispersion.
Volume: 144
Issue: 1
Pages: 249-54
Publication
First Author: Chapman DL
Year: 1996
Journal: Dev Dyn
Title: Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development.
Volume: 206
Issue: 4
Pages: 379-90
UniProt Feature
Begin: 1
Description: T-box transcription factor TBX5
Type: chain
End: 518
Publication
First Author: Li QY
Year: 1997
Journal: Nat Genet
Title: Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family.
Volume: 15
Issue: 1
Pages: 21-9
Publication
First Author: Stennard FA
Year: 2005
Journal: Development
Title: T-box transcription factors and their roles in regulatory hierarchies in the developing heart.
Volume: 132
Issue: 22
Pages: 4897-910
Publication
First Author: Breckenridge R
Year: 2007
Journal: Genesis
Title: Pan-myocardial expression of Cre recombinase throughout mouse development.
Volume: 45
Issue: 3
Pages: 135-44
Publication
First Author: Zhou YQ
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Abnormal cardiac inflow patterns during postnatal development in a mouse model of Holt-Oram syndrome.
Volume: 289
Issue: 3
Pages: H992-H1001
Publication
First Author: Gros J
Year: 2014
Journal: Science
Title: Vertebrate limb bud formation is initiated by localized epithelial-to-mesenchymal transition.
Volume: 343
Issue: 6176
Pages: 1253-6
Publication  
First Author: Ouimette JF
Year: 2010
Journal: Nat Commun
Title: Divergent transcriptional activities determine limb identity.
Volume: 1
Pages: 35
Publication    
First Author: Dai W
Year: 2019
Journal: Elife
Title: A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice.
Volume: 8
Publication
First Author: Zhu Y
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Tbx5-dependent pathway regulating diastolic function in congenital heart disease.
Volume: 105
Issue: 14
Pages: 5519-24
Publication
First Author: Luna-Zurita L
Year: 2016
Journal: Cell
Title: Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis.
Volume: 164
Issue: 5
Pages: 999-1014
Publication
First Author: Riazi AM
Year: 2005
Journal: J Biol Chem
Title: CSX/Nkx2.5 modulates differentiation of skeletal myoblasts and promotes differentiation into neuronal cells in vitro.
Volume: 280
Issue: 11
Pages: 10716-20
Publication
First Author: Minguillon C
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Tbx4/5 gene duplication and the origin of vertebrate paired appendages.
Volume: 106
Issue: 51
Pages: 21726-30
Publication
First Author: Nadadur RD
Year: 2016
Journal: Sci Transl Med
Title: Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm.
Volume: 8
Issue: 354
Pages: 354ra115
Publication
First Author: Valasek P
Year: 2011
Journal: Dev Biol
Title: Cellular and molecular investigations into the development of the pectoral girdle.
Volume: 357
Issue: 1
Pages: 108-16
Publication
First Author: Wang C
Year: 2011
Journal: PLoS One
Title: Synergistic activation of cardiac genes by myocardin and Tbx5.
Volume: 6
Issue: 8
Pages: e24242
Publication  
First Author: Beketaev I
Year: 2014
Journal: Int J Biochem Cell Biol
Title: Potentiation of Tbx5-mediated transactivation by SUMO conjugation and protein inhibitor of activated STAT 1 (PIAS1).
Volume: 50
Pages: 82-92
Publication
First Author: Munshi NV
Year: 2009
Journal: Development
Title: Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay.
Volume: 136
Issue: 15
Pages: 2665-74
Publication
First Author: Moskowitz IP
Year: 2007
Journal: Cell
Title: A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development.
Volume: 129
Issue: 7
Pages: 1365-76
Publication
First Author: Cebra-Thomas JA
Year: 2003
Journal: Dev Dyn
Title: T-box gene products are required for mesenchymal induction of epithelial branching in the embryonic mouse lung.
Volume: 226
Issue: 1
Pages: 82-90
Publication
First Author: Nadeau M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation.
Volume: 107
Issue: 45
Pages: 19356-61
Publication
First Author: Barron MR
Year: 2005
Journal: J Biol Chem
Title: Serum response factor, an enriched cardiac mesoderm obligatory factor, is a downstream gene target for Tbx genes.
Volume: 280
Issue: 12
Pages: 11816-28
Publication
First Author: Sowden JC
Year: 2001
Journal: Invest Ophthalmol Vis Sci
Title: Expression of Drosophila omb-related T-box genes in the developing human and mouse neural retina.
Volume: 42
Issue: 13
Pages: 3095-102
Publication  
First Author: Bai F
Year: 2015
Journal: Sci Rep
Title: Directed Differentiation of Embryonic Stem Cells Into Cardiomyocytes by Bacterial Injection of Defined Transcription Factors.
Volume: 5
Pages: 15014
Publication
First Author: Douglas NC
Year: 2012
Journal: Dev Dyn
Title: Dynamic expression of Tbx2 subfamily genes in development of the mouse reproductive system.
Volume: 241
Issue: 2
Pages: 365-75
Publication
First Author: Zhou CJ
Year: 2008
Journal: Dev Dyn
Title: Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes.
Volume: 237
Issue: 12
Pages: 3681-9
Publication  
First Author: Takeuchi JK
Year: 2011
Journal: Nat Commun
Title: Chromatin remodelling complex dosage modulates transcription factor function in heart development.
Volume: 2
Pages: 187
Publication
First Author: Gibson-Brown JJ
Year: 1996
Journal: Mech Dev
Title: Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity.
Volume: 56
Issue: 1-2
Pages: 93-101
Publication
First Author: De Bono C
Year: 2018
Journal: Hum Mol Genet
Title: T-box genes and retinoic acid signaling regulate the segregation of arterial and venous pole progenitor cells in the murine second heart field.
Volume: 27
Issue: 21
Pages: 3747-3760
Publication
First Author: Xie L
Year: 2012
Journal: Dev Cell
Title: Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.
Volume: 23
Issue: 2
Pages: 280-91
Publication
First Author: Lanctôt C
Year: 1999
Journal: Development
Title: Hindlimb patterning and mandible development require the Ptx1 gene.
Volume: 126
Issue: 9
Pages: 1805-10
Publication
First Author: Hoogaars WM
Year: 2004
Journal: Cardiovasc Res
Title: The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart.
Volume: 62
Issue: 3
Pages: 489-99
Publication
First Author: Plageman TF Jr
Year: 2006
Journal: Dev Dyn
Title: Microarray analysis of Tbx5-induced genes expressed in the developing heart.
Volume: 235
Issue: 10
Pages: 2868-80
Publication
First Author: Keyte AL
Year: 2010
Journal: Development
Title: Developmental origins of precocial forelimbs in marsupial neonates.
Volume: 137
Issue: 24
Pages: 4283-94
Publication
First Author: Zhou H
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes.
Volume: 112
Issue: 38
Pages: 11864-9
Publication
First Author: Hasegawa Y
Year: 2016
Journal: Development
Title: Emergence of dorsal-ventral polarity in ESC-derived retinal tissue.
Volume: 143
Issue: 21
Pages: 3895-3906
Publication
First Author: Molotkov A
Year: 2006
Journal: Development
Title: Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning.
Volume: 133
Issue: 10
Pages: 1901-10
Publication
First Author: Vanyai HK
Year: 2015
Journal: Dev Biol
Title: Mesodermal expression of Moz is necessary for cardiac septum development.
Volume: 403
Issue: 1
Pages: 22-9
Publication  
First Author: Foley TE
Year: 2019
Journal: Development
Title: Role of Cdx factors in early mesodermal fate decisions.
Volume: 146
Issue: 7
Publication  
First Author: Kim KH
Year: 2016
Journal: Sci Rep
Title: Irx3 is required for postnatal maturation of the mouse ventricular conduction system.
Volume: 6
Pages: 19197
Publication
First Author: Togi K
Year: 2004
Journal: Mol Cell Biol
Title: Role of Hand1/eHAND in the dorso-ventral patterning and interventricular septum formation in the embryonic heart.
Volume: 24
Issue: 11
Pages: 4627-35
Publication
First Author: Christoffels VM
Year: 2000
Journal: Dev Biol
Title: Chamber formation and morphogenesis in the developing mammalian heart.
Volume: 223
Issue: 2
Pages: 266-78
Publication
First Author: Pizard A
Year: 2005
Journal: Mol Cell Biol
Title: Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum.
Volume: 25
Issue: 12
Pages: 5073-83
Publication
First Author: Koibuchi N
Year: 2007
Journal: Circ Res
Title: CHF1/Hey2 plays a pivotal role in left ventricular maturation through suppression of ectopic atrial gene expression.
Volume: 100
Issue: 6
Pages: 850-5
Publication
First Author: DeLaurier A
Year: 2006
Journal: Dev Biol
Title: Pitx1 determines the morphology of muscle, tendon, and bones of the hindlimb.
Volume: 299
Issue: 1
Pages: 22-34
Publication
First Author: Pu WT
Year: 2004
Journal: Dev Biol
Title: GATA4 is a dosage-sensitive regulator of cardiac morphogenesis.
Volume: 275
Issue: 1
Pages: 235-44
Publication
First Author: Krishnan J
Year: 2008
Journal: Circ Res
Title: Essential role of developmentally activated hypoxia-inducible factor 1alpha for cardiac morphogenesis and function.
Volume: 103
Issue: 10
Pages: 1139-46
Publication
First Author: Asai R
Year: 2010
Journal: Development
Title: Endothelin receptor type A expression defines a distinct cardiac subdomain within the heart field and is later implicated in chamber myocardium formation.
Volume: 137
Issue: 22
Pages: 3823-33