| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
TCEAL1, also known as p21/SIIR, is a Ser/Arg/Pro-rich nuclear phosphoprotein that is 48% similar to transcription factor SII []. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7537400 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760621 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7537432 |
| Age: |
embryonic day 13.5 |
| Image: |
S7 Tceal1 |
|
| Specimen Label: |
S7 Tceal1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7537400 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1751821 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7537432 |
| Age: |
embryonic day 13.5 |
| Image: |
S7 Tceal1 |
|
| Specimen Label: |
S7 Tceal1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7537400 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672821 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7537432 |
| Age: |
embryonic day 13.5 |
| Image: |
S7 Tceal1 |
|
| Specimen Label: |
S7 Tceal1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7537400 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3598821 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7537432 |
| Age: |
embryonic day 13.5 |
| Image: |
S7 Tceal1 |
|
| Specimen Label: |
S7 Tceal1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7537400 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1666821 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7537432 |
| Age: |
embryonic day 13.5 |
| Image: |
S7 Tceal1 |
|
| Specimen Label: |
S7 Tceal1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7537400 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716821 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7537432 |
| Age: |
embryonic day 13.5 |
| Image: |
S7 Tceal1 upper right |
|
| Specimen Label: |
S7 Tceal1 upper right |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7537400 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737321 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7537432 |
| Age: |
embryonic day 13.5 |
| Image: |
S7 Tceal1 lower left |
|
| Specimen Label: |
S7 Tceal1 lower left |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7537400 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1783821 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7537432 |
| Age: |
embryonic day 13.5 |
| Image: |
S7 Tceal1 upper right |
|
| Specimen Label: |
S7 Tceal1 upper right |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7537400 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1702321 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7537432 |
| Age: |
embryonic day 13.5 |
| Image: |
S7 Tceal1 lower right |
|
| Specimen Label: |
S7 Tceal1 lower right |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7537400 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2023-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1679721 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7537432 |
| Age: |
embryonic day 13.5 |
| Image: |
S7 Tceal1 upper left |
|
| Specimen Label: |
S7 Tceal1 upper left |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pillutla RC |
| Year: |
1999 |
| Journal: |
Genomics |
| Title: |
Genomic structure and chromosomal localization of TCEAL1, a human gene encoding the nuclear phosphoprotein p21/SIIR. |
| Volume: |
56 |
| Issue: |
2 |
| Pages: |
217-20 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
165
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1507763 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1788323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828629 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006652_12 |
|
| Specimen Label: |
euxassay_006652_12 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1507763 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1788323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828629 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006652_13 |
|
| Specimen Label: |
euxassay_006652_13 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1507763 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1788323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828629 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006652_14 |
|
| Specimen Label: |
euxassay_006652_14 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1507763 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1788323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828629 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006652_15 |
|
| Specimen Label: |
euxassay_006652_15 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1507763 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1788323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828629 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006652_16 |
|
| Specimen Label: |
euxassay_006652_16 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1507763 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1788323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4828629 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_006652_17 |
|
| Specimen Label: |
euxassay_006652_17 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Navas-Pérez E |
| Year: |
2020 |
| Journal: |
Genome Biol |
| Title: |
Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions. |
| Volume: |
21 |
| Issue: |
1 |
| Pages: |
267 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suzuki H |
| Year: |
2001 |
| Journal: |
Genome Res |
| Title: |
Protein-protein interaction panel using mouse full-length cDNAs. |
| Volume: |
11 |
| Issue: |
10 |
| Pages: |
1758-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Strausberg RL |
| Year: |
2002 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
| Volume: |
99 |
| Issue: |
26 |
| Pages: |
16899-903 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
| Year: |
2001 |
|
| Title: |
LocusLink Collaboration |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI and IMPC |
| Year: |
2017 |
| Journal: |
MGI Direct Data Submission |
| Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yokoyama S |
| Year: |
2009 |
| Journal: |
Dev Cell |
| Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
| Volume: |
17 |
| Issue: |
6 |
| Pages: |
836-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Velocigene |
| Year: |
2008 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
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•
•
•
•
•
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| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
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| Title: |
Nomenclature Committee Use |
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•
•
•
•
•
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| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
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•
•
•
•
•
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| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
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| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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•
•
•
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| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
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•
•
•
•
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| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
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| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
•
•
•
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Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
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1 |
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e1000582 |
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•
•
•
•
|
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| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
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Entrez Gene Load |
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•
•
•
•
•
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Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
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Allen Brain Atlas: mouse riboprobes |
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•
•
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•
•
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| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
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Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Bairoch A |
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1999 |
| Journal: |
Database Release |
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SWISS-PROT Annotated protein sequence database |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
200
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
117
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
104
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
200
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
98
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
200
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
200
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
176
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
56
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
46
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rattan R |
| Year: |
2010 |
| Journal: |
Oncogene |
| Title: |
TCEAL7, a putative tumor suppressor gene, negatively regulates NF-kappaB pathway. |
| Volume: |
29 |
| Issue: |
9 |
| Pages: |
1362-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kazi JU |
| Year: |
2015 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Brain-Expressed X-linked (BEX) proteins in human cancers. |
| Volume: |
1856 |
| Issue: |
2 |
| Pages: |
226-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chien J |
| Year: |
2005 |
| Journal: |
Oncogene |
| Title: |
Epigenetic silencing of TCEAL7 (Bex4) in ovarian cancer. |
| Volume: |
24 |
| Issue: |
32 |
| Pages: |
5089-100 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This is a family of transcription elongation factors which includes those referred to as Bex (brain-expressed X-linked) proteins as well as those named TCEAL (transcription elongation factor A protein-like). Bex proteins are expressed in a wide range of tissues and are known to play a role in neuronal development. They seem to have have distinct roles in cancers []. Bex1 was shown to be a novel link between neurotrophin signalling, the cell cycle, and neuronal differentiation, suggesting it might function by coordinating internal cellular states with the ability of cells to respond to external signals []. TCEAL7 has been shown negatively to regulate the NF-kappaB pathway, hence being important in ovarian cancer as it one of the genes frequently downregulated in this cancer [, ]. Apart from TCEAL7, there are other five members of the TCEAL family, i.e. TCEAL1, TCEAL3, TCEAL4, TCEAL5 and TCEAL8. TCEAL1 was shown involved in the apoptosis of human cancer cells []. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
124
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
114
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
129
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
118
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
128
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
118
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vilar M |
| Year: |
2006 |
| Journal: |
EMBO J |
| Title: |
Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle. |
| Volume: |
25 |
| Issue: |
6 |
| Pages: |
1219-30 |
|
•
•
•
•
•
|